3O6Q
| The Structure of SpoIISA and SpoIISB, a Toxin - Antitoxin System | Descriptor: | Stage II sporulation protein SA, Stage II sporulation protein SB | Authors: | Levdikov, V.M, Blagova, E.V, Lebedev, A.A, Wilkinson, A.J, Florek, P, Barak, I. | Deposit date: | 2010-07-29 | Release date: | 2010-12-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The structure and interactions of SpoIISA and SpoIISB, a toxin-antitoxin system in Bacillus subtilis. J.Biol.Chem., 161, 2010
|
|
3O9P
| The structure of the Escherichia coli murein tripeptide binding protein MppA | Descriptor: | L-ALA-GAMMA-D-GLU-MESO-DIAMINOPIMELIC ACID, Periplasmic murein peptide-binding protein, ZINC ION | Authors: | Maqbool, A, Levdikov, V.M, Blagova, E.V, Wilkinson, A.J, Thomas, G.H. | Deposit date: | 2010-08-04 | Release date: | 2011-07-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Compensating Stereochemical Changes Allow Murein Tripeptide to Be Accommodated in a Conventional Peptide-binding Protein. J.Biol.Chem., 286, 2011
|
|
7ATR
| |
6I3G
| Crystal structure of a putative peptide binding protein AppA from Clostridium difficile | Descriptor: | ABC transporter, substrate-binding protein, family 5, ... | Authors: | Hughes, A.M, Wilkinson, A, Dodson, E. | Deposit date: | 2018-11-06 | Release date: | 2019-04-10 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the putative peptide-binding protein AppA from Clostridium difficile. Acta Crystallogr.,Sect.F, 75, 2019
|
|
3DD6
| Crystal structure of Rph, an exoribonuclease from Bacillus anthracis at 1.7 A resolution | Descriptor: | Ribonuclease PH, SULFATE ION | Authors: | Rawlings, A.E, Blagova, E.V, Levdikov, V.M, Fogg, M.J, Wilson, K.S, Wilkinson, A.J, Structural Proteomics in Europe 2 (SPINE-2) | Deposit date: | 2008-06-05 | Release date: | 2009-02-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.702 Å) | Cite: | The structure of Rph, an exoribonuclease from Bacillus anthracis, at 1.7 A resolution. Acta Crystallogr.,Sect.F, 65, 2009
|
|
2W41
| Crystal structure of Plasmodium falciparum glycerol kinase with ADP | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL KINASE, ... | Authors: | Schnick, C, Polley, S.D, Fivelman, Q.L, Ranford-Cartwright, L, Wilkinson, S.R, Brannigan, J.A, Wilkinson, A.J, Baker, D.A. | Deposit date: | 2008-11-18 | Release date: | 2008-12-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Structure and Non-Essential Function of Glycerol Kinase in Plasmodium Falciparum Blood Stages. Mol.Microbiol., 71, 2009
|
|
2W40
| Crystal structure of Plasmodium falciparum glycerol kinase with bound glycerol | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, GLYCEROL KINASE, ... | Authors: | Schnick, C, Polley, S.D, Fivelman, Q.L, Ranford-Cartwright, L, Wilkinson, S.R, Brannigan, J.A, Wilkinson, A.J, Baker, D.A. | Deposit date: | 2008-11-18 | Release date: | 2008-12-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Structure and Non-Essential Function of Glycerol Kinase in Plasmodium Falciparum Blood Stages. Mol.Microbiol., 71, 2009
|
|
5O4V
| P.vivax NMT with aminomethylindazole and quinoline inhibitors bound | Descriptor: | 1-[5-(4-fluoranyl-2-methyl-phenyl)-1~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine, 2-oxopentadecyl-CoA, CHLORIDE ION, ... | Authors: | Brannigan, J.A, Wilkinson, A.J. | Deposit date: | 2017-05-31 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus. Nat Chem, 10, 2018
|
|
5O6J
| Human NMT1 in complex with myristoyl-CoA and inhibitor IMP-1031 | Descriptor: | 1-[5-[3-fluoranyl-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-1-methyl-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine, Glycylpeptide N-tetradecanoyltransferase 1, MAGNESIUM ION, ... | Authors: | Brannigan, J.A, Wilkinson, A.J. | Deposit date: | 2017-06-06 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus. Nat Chem, 10, 2018
|
|
5O6H
| Human NMT1 in complex with myristoyl-CoA and inhibitor IMP-917 | Descriptor: | 1-[5-[4-fluoranyl-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-2~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Brannigan, J.A, Wilkinson, A.J. | Deposit date: | 2017-06-06 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus. Nat Chem, 10, 2018
|
|
5O48
| P.vivax NMT with an aminomethylindazole inhibitor bound | Descriptor: | 1-[5-(4-fluoranyl-2-methyl-phenyl)-1~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine, 2-oxopentadecyl-CoA, CHLORIDE ION, ... | Authors: | Brannigan, J.A, Wilkinson, A.J. | Deposit date: | 2017-05-26 | Release date: | 2018-05-16 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus. Nat Chem, 10, 2018
|
|
2PFM
| Crystal Structure of Adenylosuccinate Lyase (PurB) from Bacillus anthracis | Descriptor: | Adenylosuccinate lyase, MALONATE ION | Authors: | Levdikov, V.M, Blagova, E.V, Baumgart, M, Moroz, O.V, Wilkinson, A.J, Wilson, K.S. | Deposit date: | 2007-04-05 | Release date: | 2007-04-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Adenylosuccinate Lyase (PurB) from Bacillus anthracis To be Published
|
|
4TPS
| Sporulation Inhibitor of DNA Replication, SirA, in complex with Domain I of DnaA | Descriptor: | ACETATE ION, BETA-MERCAPTOETHANOL, Chromosomal replication initiator protein DnaA, ... | Authors: | Jameson, K.H, Turkenburg, J.P, Fogg, M.J, Grahl, A, Wilkinson, A.J. | Deposit date: | 2014-06-09 | Release date: | 2014-07-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure and interactions of the Bacillus subtilis sporulation inhibitor of DNA replication, SirA, with domain I of DnaA. Mol.Microbiol., 93, 2014
|
|
4PEL
| S1C mutant of Penicillin G acylase from Kluyvera citrophila | Descriptor: | CALCIUM ION, Penicillin G acylase subunit alpha, Penicillin G acylase subunit beta | Authors: | Ramasamy, S, Chand, D, Varshney, N.K, Brannigan, J.A, Wilkinson, A.J, Suresh, C.G. | Deposit date: | 2014-04-24 | Release date: | 2015-07-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Penicillin G acylase To Be Published
|
|
1JEU
| OLIGO-PEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH KEK | Descriptor: | OLIGO-PEPTIDE BINDING PROTEIN, PEPTIDE LYS GLU LYS, URANYL (VI) ION | Authors: | Tame, J, Wilkinson, A.J. | Deposit date: | 1996-07-03 | Release date: | 1997-05-15 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | The role of water in sequence-independent ligand binding by an oligopeptide transporter protein. Nat.Struct.Biol., 3, 1996
|
|
1JEV
| OLIGO-PEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH KWK | Descriptor: | OLIGO-PEPTIDE BINDING PROTEIN, PEPTIDE LYS TRP LYS, URANYL (VI) ION | Authors: | Tame, J, Wilkinson, A.J. | Deposit date: | 1996-07-03 | Release date: | 1997-05-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | The role of water in sequence-independent ligand binding by an oligopeptide transporter protein. Nat.Struct.Biol., 3, 1996
|
|
1JET
| OLIGO-PEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH KAK | Descriptor: | OLIGO-PEPTIDE BINDING PROTEIN, PEPTIDE LYS ALA LYS, URANYL (VI) ION | Authors: | Tame, J, Wilkinson, A.J. | Deposit date: | 1996-07-03 | Release date: | 1997-05-15 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | The role of water in sequence-independent ligand binding by an oligopeptide transporter protein. Nat.Struct.Biol., 3, 1996
|
|
4PEM
| Crystal Structure of S1G mutant of Penicillin G Acylase from Kluyvera citrophila | Descriptor: | CALCIUM ION, Penicillin G acylase Alpha, Penicillin G acylase Beta | Authors: | Ramasamy, S, Varshney, N.K, Brannigan, J.A, Wilkinson, A.J, Suresh, C.G. | Deposit date: | 2014-04-24 | Release date: | 2015-07-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of S1G mutant of Penicillin G Acylase from Kluyvera citrophilla To be Published
|
|
3T9Q
| |
3T91
| Structure of the Phosphatase Domain of the Cell Fate Determinant SpoIIE from Bacillus subtilis | Descriptor: | MANGANESE (II) ION, Stage II sporulation protein E, alpha-D-mannopyranose, ... | Authors: | Levdikov, V.M, Blagova, E.V, Wilkinson, A.J. | Deposit date: | 2011-08-02 | Release date: | 2011-12-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Structure of the phosphatase domain of the cell fate determinant SpoIIE from Bacillus subtilis. J.Mol.Biol., 415, 2012
|
|
4ACI
| Structure of the C. glutamicum AcnR Crystal Form II | Descriptor: | CITRIC ACID, GLYCEROL, HTH-TYPE TRANSCRIPTIONAL REPRESSOR ACNR, ... | Authors: | Garcia-Nafria, J, Baumgart, M, Turkenburg, J.P, Wilkinson, A.J, Bott, M, Wilson, K.S. | Deposit date: | 2011-12-15 | Release date: | 2012-12-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal and Solution Studies Reveal that the Transcriptional Regulator Acnr of Corynebacterium Glutamicum is Regulated by Citrate:Mg2+ Binding to a Non-Canonical Pocket. J.Biol.Chem., 288, 2013
|
|
3TUF
| |
3QQ6
| The N-terminal DNA binding domain of SinR from Bacillus subtilis | Descriptor: | HTH-type transcriptional regulator sinR | Authors: | Colledge, V, Fogg, M.J, Levdikov, V.M, Dodson, E.J, Wilkinson, A.J. | Deposit date: | 2011-02-15 | Release date: | 2011-06-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and Organisation of SinR, the Master Regulator of Biofilm Formation in Bacillus subtilis. J.Mol.Biol., 411, 2011
|
|
1RKM
| STRUCTURE OF OPPA | Descriptor: | OLIGO-PEPTIDE BINDING PROTEIN | Authors: | Sleigh, S.H, Tame, J.R.H, Wilkinson, A.J. | Deposit date: | 1997-03-25 | Release date: | 1997-07-29 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Peptide binding in OppA, the crystal structures of the periplasmic oligopeptide binding protein in the unliganded form and in complex with lysyllysine. Biochemistry, 36, 1997
|
|
4AF5
| Structure of the C. glutamicum AcnR Crystal Form I | Descriptor: | CITRIC ACID, HTH-TYPE TRANSCRIPTIONAL REPRESSOR ACNR COMPND 2, MAGNESIUM ION | Authors: | Garcia-Nafria, J, Baumgart, M, Turkenburg, J.P, Wilkinson, A.J, Bott, M, Wilson, K.S. | Deposit date: | 2012-01-17 | Release date: | 2013-01-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal and Solution Studies Reveal that the Transcriptional Regulator Acnr of Corynebacterium Glutamicum is Regulated by Citrate:Mg2+ Binding to a Non-Canonical Pocket. J.Biol.Chem., 288, 2013
|
|