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PDB: 80 件

4PSG
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Crystal Structure of C.elegans Thymidylate Synthase in complex with an inhibitor N(4)OHdCMP
分子名称: 2'-deoxy-N-hydroxycytidine 5'-(dihydrogen phosphate), Thymidylate synthase
著者Wilk, P, Jarmula, A, Rode, W.
登録日2014-03-07
公開日2015-02-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of C.elegans Thymidylate Synthase in complex with an inhibitor N(4)OHdCMP
To be Published
6QSB
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Crystal Structure of Arg470His mutant of Human Prolidase with Mn ions
分子名称: GLYCEROL, MANGANESE (II) ION, Xaa-Pro dipeptidase
著者Wilk, P, Wator, E, Weiss, M.S.
登録日2019-02-20
公開日2020-03-18
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural analysis of new compound heterozygous variants in PEPD gene identified in a patient with Prolidase Deficiency diagnosed by exome sequencing.
Genet Mol Biol, 44, 2021
6QSC
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Crystal Structure of Arg470His mutant of Human Prolidase with Mn ions and GlyPro ligand
分子名称: GLYCEROL, GLYCINE, MANGANESE (II) ION, ...
著者Wilk, P, Wator, E, Weiss, M.S.
登録日2019-02-20
公開日2020-03-18
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.569 Å)
主引用文献Structural analysis of new compound heterozygous variants in PEPD gene identified in a patient with Prolidase Deficiency diagnosed by exome sequencing.
Genet Mol Biol, 44, 2021
6TXN
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Crystal structure of thermotoga maritima Ferritin in apo form
分子名称: EICOSANE, Ferritin, GLYCEROL, ...
著者Wilk, P, Grudnik, P, Kumar, M, Heddle, J, Chakraborti, S.
登録日2020-01-14
公開日2021-07-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献A single residue can modulate nanocage assembly in salt dependent ferritin.
Nanoscale, 13, 2021
6TXH
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Crystal structure of thermotoga maritima Ferritin in apo form
分子名称: EICOSANE, Ferritin, GLYCEROL, ...
著者Wilk, P, Grudnik, P, Kumar, M, Heddle, J, Chakraborti, S.
登録日2020-01-14
公開日2021-07-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.198 Å)
主引用文献A single residue can modulate nanocage assembly in salt dependent ferritin.
Nanoscale, 13, 2021
6TXM
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Crystal structure of thermotoga maritima E65R Ferritin
分子名称: EICOSANE, Ferritin, GLYCEROL, ...
著者Wilk, P, Grudnik, P, Kumar, M, Heddle, J, Chakraborti, S.
登録日2020-01-14
公開日2021-07-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.198 Å)
主引用文献A single residue can modulate nanocage assembly in salt dependent ferritin.
Nanoscale, 13, 2021
6TXL
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Crystal structure of thermotoga maritima E65Q Ferritin
分子名称: EICOSANE, FE (III) ION, Ferritin, ...
著者Wilk, P, Grudnik, P, Kumar, M, Heddle, J, Chakraborti, S.
登録日2020-01-14
公開日2021-07-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献A single residue can modulate nanocage assembly in salt dependent ferritin.
Nanoscale, 13, 2021
6TXJ
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Crystal structure of thermotoga maritima A42V E65D Ferritin
分子名称: EICOSANE, FE (III) ION, Ferritin, ...
著者Wilk, P, Grudnik, P, Kumar, M, Heddle, J, Chakraborti, S, Biela, A.P.
登録日2020-01-14
公開日2021-07-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献A single residue can modulate nanocage assembly in salt dependent ferritin.
Nanoscale, 13, 2021
6TXK
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Crystal structure of thermotoga maritima E65K Ferritin
分子名称: EICOSANE, FE (III) ION, Ferritin, ...
著者Wilk, P, Grudnik, P, Kumar, M, Heddle, J, Chakraborti, S.
登録日2020-01-14
公開日2021-07-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.359 Å)
主引用文献A single residue can modulate nanocage assembly in salt dependent ferritin.
Nanoscale, 13, 2021
6TXI
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Crystal structure of thermotoga maritima E65A Ferritin
分子名称: EICOSANE, FE (III) ION, Ferritin, ...
著者Wilk, P, Grudnik, P, Kumar, M, Heddle, J, Chakraborti, S.
登録日2020-01-14
公開日2021-07-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.759 Å)
主引用文献A single residue can modulate nanocage assembly in salt dependent ferritin.
Nanoscale, 13, 2021
6F6Z
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Mouse Thymidylate Synthase Cocrystallized with N(4)OHdCMP and Soaked in Methylenetetrahydrofolate
分子名称: (2~{S})-2-[[4-[[(6~{R})-2-azanyl-4-oxidanylidene-5,6,7,8-tetrahydro-1~{H}-pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acid, 2'-deoxy-N-hydroxycytidine 5'-(dihydrogen phosphate), Thymidylate synthase
著者Wilk, P, Jarmula, A, Maj, P, Rode, W.
登録日2017-12-06
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.127 Å)
主引用文献Molecular Mechanism of Thymidylate Synthase Inhibition by N4-Hydroxy-dCMP in View of Spectrophotometric and Crystallographic Studies
Int J Mol Sci, 22, 2021
6ZQ5
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BU of 6zq5 by Molmil
Crystal structure of Chaetomium thermophilum Glycerol Kinase in P2221 space group
分子名称: 1,2-ETHANEDIOL, Glycerol kinase-like protein
著者Wilk, P, Wator, E, Malecki, P, Grudnik, P.
登録日2020-07-09
公開日2020-12-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structural Characterization of Glycerol Kinase from the Thermophilic Fungus Chaetomium thermophilum .
Int J Mol Sci, 21, 2020
6ZQ8
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Crystal structure of Chaetomium thermophilum Glycerol Kinase in P3221 space group
分子名称: Glycerol kinase-like protein
著者Wilk, P, Wator, E, Malecki, P, Tokarz, P, Grudnik, P.
登録日2020-07-09
公開日2020-12-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structural Characterization of Glycerol Kinase from the Thermophilic Fungus Chaetomium thermophilum .
Int J Mol Sci, 21, 2020
4IQB
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High Resolution Crystal Structure of C.elegans Thymidylate Synthase
分子名称: SULFATE ION, Thymidylate synthase
著者Wilk, P, Dowiercial, A, Banaszak, K, Jarmula, A, Rypniewski, W, Rode, W.
登録日2013-01-11
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS.
J. Mol. Graph. Model., 77, 2017
7B9P
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Structure of Ribonucleotide reductase from Rhodobacter sphaeroides
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, Vitamin B12-dependent ribonucleotide reductase
著者Wilk, P, Feiler, C, Loderer, C, Kabinger, F.
登録日2020-12-14
公開日2022-01-12
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.646 Å)
主引用文献HUG Domain Is Responsible for Active Dimer Stabilization in an NrdJd Ribonucleotide Reductase.
Biochemistry, 61, 2022
6ZQ4
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Crystal structure of Chaetomium thermophilum Glycerol Kinase in complex with substrate in P1 space group
分子名称: GLYCEROL, Glycerol kinase-like protein, PHOSPHATE ION
著者Wilk, P, Wator, E, Grudnik, P.
登録日2020-07-09
公開日2020-12-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural Characterization of Glycerol Kinase from the Thermophilic Fungus Chaetomium thermophilum .
Int J Mol Sci, 21, 2020
6ZQ6
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BU of 6zq6 by Molmil
Crystal structure of Chaetomium thermophilum Glycerol Kinase in complex with glycerol in P21212 space group
分子名称: ACETATE ION, GLYCEROL, Glycerol kinase-like protein
著者Wilk, P, Wator, E, Grudnik, P.
登録日2020-07-09
公開日2020-12-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Characterization of Glycerol Kinase from the Thermophilic Fungus Chaetomium thermophilum .
Int J Mol Sci, 21, 2020
6ZQ7
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Crystal structure of Chaetomium thermophilum Glycerol Kinase in I222 space group
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Glycerol kinase-like protein
著者Wilk, P, Wator, E, Grudnik, P.
登録日2020-07-09
公開日2020-12-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.421 Å)
主引用文献Structural Characterization of Glycerol Kinase from the Thermophilic Fungus Chaetomium thermophilum .
Int J Mol Sci, 21, 2020
6H2P
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Crystal Structure of Arg184Gln mutant of Human Prolidase with Mn ions and Cacodylate ligand
分子名称: CACODYLATE ION, GLYCEROL, MANGANESE (II) ION, ...
著者Wilk, P, Piwowarczyk, R, Weiss, M.S.
登録日2018-07-14
公開日2018-08-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.479 Å)
主引用文献Structural basis for prolidase deficiency disease mechanisms.
FEBS J., 285, 2018
6H2Q
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Crystal Structure of Arg184Gln mutant of Human Prolidase with Mn ions and LeuPro ligand
分子名称: GLYCEROL, LEUCINE, MANGANESE (II) ION, ...
著者Wilk, P, Piwowarczyk, R, Weiss, M.S.
登録日2018-07-14
公開日2018-08-15
最終更新日2020-04-22
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural basis for prolidase deficiency disease mechanisms.
FEBS J., 285, 2018
4IRR
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BU of 4irr by Molmil
Crystal Structure of C.elegans Thymidylate Synthase in Complex with dUMP
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Thymidylate synthase
著者Wilk, P, Dowiercial, A, Banaszak, K, Jarmula, A, Rypniewski, W, Rode, W.
登録日2013-01-15
公開日2014-01-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Crystal Structure of C.elegans Thymidylate Synthase in Complex with dUMP
To be Published
4ISW
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Crystal Structure of Phosphorylated C.elegans Thymidylate Synthase in Complex with dUMP
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase
著者Wilk, P, Dowiercial, A, Banaszak, K, Jarmula, A, Rypniewski, W, Rode, W.
登録日2013-01-17
公開日2013-12-11
最終更新日2014-01-15
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Crystal structure of phosphoramide-phosphorylated thymidylate synthase reveals pSer127, reflecting probably pHis to pSer phosphotransfer.
Bioorg.Chem., 52C, 2013
7PQF
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Crystal structure of Campylobacter jejuni DsbA2
分子名称: Thiol:disulfide interchange protein DsbA/DsbL
著者Wilk, P, Banas, A.M, Bocian-Ostrzycka, K.M, Jagusztyn-Krynicka, E.K.
登録日2021-09-17
公開日2021-12-29
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Interplay between DsbA1, DsbA2 and C8J_1298 Periplasmic Oxidoreductases of Campylobacter jejuni and Their Impact on Bacterial Physiology and Pathogenesis.
Int J Mol Sci, 22, 2021
7PQ7
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Crystal structure of Campylobacter jejuni DsbA1
分子名称: TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, Thiol:disulfide interchange protein DsbA
著者Wilk, P, Orlikowska, M, Banas, A.M, Bocian-Ostrzycka, K.M, Jagusztyn-Krynicka, E.K.
登録日2021-09-16
公開日2021-12-29
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Interplay between DsbA1, DsbA2 and C8J_1298 Periplasmic Oxidoreductases of Campylobacter jejuni and Their Impact on Bacterial Physiology and Pathogenesis.
Int J Mol Sci, 22, 2021
5M4Z
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Crystal structure of the complex of T.spiralis thymidylate synthase with N(4)-hydroxy-2'-deoxycytidine-5'-monophosphate, crystallized in the presence of N(5,10)-methylenetetrahydrofolate
分子名称: GLYCEROL, Thymidylate synthase, [(2~{R},3~{S},5~{R})-5-[(4~{E})-4-hydroxyimino-2-oxidanylidene-1,3-diazinan-1-yl]-3-oxidanyl-oxolan-2-yl]methyl dihydrogen phosphate
著者Wilk, P, Maj, P, Jarmula, A, Dowiercial, A, Rode, W.
登録日2016-10-19
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.179 Å)
主引用文献Molecular Mechanism of Thymidylate Synthase Inhibition by N 4 -Hydroxy-dCMP in View of Spectrophotometric and Crystallographic Studies.
Int J Mol Sci, 22, 2021

 

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