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PDB: 40 件

6YCV
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BU of 6ycv by Molmil
2'-F-riboguanosine and LNA modified hybrid type G-quadruplex with V-loop
分子名称: DNA (5'-D(*GP*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*(GF2))-R(P*(LCG))-D(P*GP*GP*AP*CP*GP*GP*G)-3')
著者Weisz, K, Haase, L.
登録日2020-03-19
公開日2020-09-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Locked nucleic acid building blocks as versatile tools for advanced G-quadruplex design.
Nucleic Acids Res., 48, 2020
6YEP
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BU of 6yep by Molmil
LNA modified G-quadruplex with flipped G-tract and central tetrad
分子名称: DNA (5'-D(*GP*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*G)-R(P*(LCG))-D(P*GP*GP*AP*CP*GP*GP*G)-3')
著者Weisz, K, Haase, L.
登録日2020-03-25
公開日2020-09-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Locked nucleic acid building blocks as versatile tools for advanced G-quadruplex design.
Nucleic Acids Res., 48, 2020
6ZTE
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BU of 6zte by Molmil
Structure of a parallel c-myc modified with 5' duplex stem-loop and 3' diagonal snap-back loop
分子名称: DNA (36-MER)
著者Vianney, Y.M, Weisz, K.
登録日2020-07-20
公開日2020-10-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Quadruplex-Duplex Junction: A High-Affinity Binding Site for Indoloquinoline Ligands.
Chemistry, 26, 2020
6R9K
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BU of 6r9k by Molmil
A quadruplex hybrid structure with lpp loop orientation and 3 syn residues
分子名称: DNA (25-MER)
著者Karg, B, Weisz, K.
登録日2019-04-03
公開日2019-07-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Duplex-Guided Refolding into Novel G-Quadruplex (3+1) Hybrid Conformations.
Angew.Chem.Int.Ed.Engl., 58, 2019
6R9L
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BU of 6r9l by Molmil
A quadruplex hybrid structure with lpp loop orientation and 5 syn residues
分子名称: DNA (25-MER)
著者Karg, B, Weisz, K.
登録日2019-04-03
公開日2019-07-03
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Duplex-Guided Refolding into Novel G-Quadruplex (3+1) Hybrid Conformations.
Angew.Chem.Int.Ed.Engl., 58, 2019
7O1H
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BU of 7o1h by Molmil
Hybrid-2R quadruplex-duplex with (-p-p-l) topology and 3 syn residues
分子名称: DNA (31-MER)
著者Mohr, S, Vianney, Y.M, Weisz, K.
登録日2021-03-29
公開日2021-05-19
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Expanding the Topological Landscape by a G-Column Flip of a Parallel G-Quadruplex.
Chemistry, 27, 2021
7ATZ
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BU of 7atz by Molmil
G-quadruplex with V-shaped loop from the first repeat of KCNN4 minisatellite
分子名称: DNA (5'-D(*GP*GP*TP*CP*TP*GP*AP*GP*GP*GP*AP*GP*AP*GP*GP*GP*GP*CP*TP*GP*GP*GP*T)-3')
著者Vianney, Y.M, Weisz, K.
登録日2020-11-02
公開日2021-04-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献First Tandem Repeat of a Potassium Channel KCNN4 Minisatellite Folds into a V-Loop G-Quadruplex Structure.
Biochemistry, 60, 2021
5OV2
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BU of 5ov2 by Molmil
2'F-ANA-G modified quadruplex with a flipped tetrad
分子名称: artificial quadruplex with propeller, diagonal, and lateral loop
著者Dickerhoff, J, Weisz, K.
登録日2017-08-27
公開日2017-10-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Nonconventional C-HF Hydrogen Bonds Support a Tetrad Flip in Modified G-Quadruplexes.
J Phys Chem Lett, 8, 2017
7PNE
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BU of 7pne by Molmil
Parallel Q-D hybrid with 3' duplex stem-loop as a lateral snapback loop
分子名称: TTAMycdup-3sbl
著者Vianney, Y.M, Weisz, K.
登録日2021-09-06
公開日2021-12-29
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Indoloquinoline Ligands Favor Intercalation at Quadruplex-Duplex Interfaces.
Chemistry, 28, 2022
7PNG
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BU of 7png by Molmil
Solution structure of 1:1 complex of an indoloquinoline derivative SYUIQ-5 to parallel quadruplex-duplex (Q-D) hybrid
分子名称: DNA (37-MER), ~{N}-(5~{H}-indolo[3,2-b]quinolin-11-yl)-~{N}',~{N}'-dimethyl-propane-1,3-diamine
著者Vianney, Y.M, Weisz, K.
登録日2021-09-06
公開日2021-12-29
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Indoloquinoline Ligands Favor Intercalation at Quadruplex-Duplex Interfaces.
Chemistry, 28, 2022
5MBR
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BU of 5mbr by Molmil
Quadruplex with flipped tetrad formed by a human telomeric sequence
分子名称: G-quadruplex formed by a human telomeric sequence modified with 2'-fluoro-2'-deoxyriboguanosine
著者Dickerhoff, J, Haase, L, Langel, W, Weisz, K.
登録日2016-11-08
公開日2017-04-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Tracing Effects of Fluorine Substitutions on G-Quadruplex Conformational Changes.
ACS Chem. Biol., 12, 2017
5MCR
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BU of 5mcr by Molmil
Quadruplex with flipped tetrad formed by an artificial sequence
分子名称: Artificial quadruplex with propeller, diagonal and lateral loop
著者Dickerhoff, J, Haase, L, Langel, W, Weisz, K.
登録日2016-11-10
公開日2017-04-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Tracing Effects of Fluorine Substitutions on G-Quadruplex Conformational Changes.
ACS Chem. Biol., 12, 2017
7ZEM
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BU of 7zem by Molmil
Structure of a parallel G-quadruplex with a snapback loop
分子名称: DNA (5'-D(*(DT5)P*GP*GP*CP*TP*AP*GP*GP*GP*TP*CP*AP*GP*GP*GP*TP*GP*GP*GP*TP*CP*AP*(DG3))-3')
著者Jana, J, Vianney, Y.M, Schroeder, N, Weisz, K.
登録日2022-03-31
公開日2022-06-15
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Guiding the folding of G-quadruplexes through loop residue interactions.
Nucleic Acids Res., 50, 2022
8ABD
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BU of 8abd by Molmil
Solution structure of Phen-DC3 intercalating into a quadruplex-duplex hybrid
分子名称: DNA (36-MER), N2,N9-bis(1-methylquinolin-3-yl)-1,10-phenanthroline-2,9-dicarboxamide
著者Vianney, Y.M, Weisz, K.
登録日2022-07-04
公開日2022-11-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献High-affinity binding at quadruplex-duplex junctions: rather the rule than the exception.
Nucleic Acids Res., 50, 2022
8ABN
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BU of 8abn by Molmil
Solution structure of a phenyl-indoloquinoline intercalating into a quadruplex-duplex hybrid
分子名称: DNA (27-MER), diethyl-[3-[[4-(4,5,9-trimethyl-10H-indolo[3,2-b]quinolin-5-ium-11-yl)phenyl]carbonylamino]propyl]azanium
著者Vianney, Y.M, Weisz, K.
登録日2022-07-04
公開日2022-11-16
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献High-affinity binding at quadruplex-duplex junctions: rather the rule than the exception.
Nucleic Acids Res., 50, 2022
7ZEO
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BU of 7zeo by Molmil
Structure of a hybrid-type G-quadruplex with a snapback loop and an all-syn G-column (hybrid-1R)
分子名称: DNA (5'-D(*(DG5)P*(BGM)P*CP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*CP*AP*(DG3))-3')
著者Jana, J, Vianney, Y.M, Schroeder, N, Weisz, K.
登録日2022-03-31
公開日2022-06-15
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Guiding the folding of G-quadruplexes through loop residue interactions.
Nucleic Acids Res., 50, 2022
7ZEK
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BU of 7zek by Molmil
Structure of a hybrid-type G-quadruplex with a snapback loop (hybrid 1R')
分子名称: DNA (5'-D(*(DG5)P*GP*CP*TP*AP*(BG)P*GP*GP*TP*CP*AP*GP*GP*GP*TP*GP*GP*GP*TP*CP*AP*(DG3))-3')
著者Jana, J, Vianney, Y.M, Schroeder, N, Weisz, K.
登録日2022-03-31
公開日2022-06-22
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Guiding the folding of G-quadruplexes through loop residue interactions.
Nucleic Acids Res., 50, 2022
2KTT
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BU of 2ktt by Molmil
Solution Structure of a Covalently Bound Pyrrolo[2,1-c][1,4]benzodiazepine-Benzimidazole Hybrid to a 10mer DNA Duplex
分子名称: (11aS)-7-methoxy-8-(3-{4-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]phenoxy}propoxy)-1,2,3,10,11,11a-hexahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one, 5'-D(*AP*AP*CP*AP*AP*TP*TP*GP*TP*T)-3'
著者Rettig, M, Weingarth, M, Langel, W, Kamal, A, Kumar, P.P, Weisz, K.
登録日2010-02-08
公開日2010-03-09
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of a covalently bound pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole hybrid to a 10mer DNA duplex.
Biochemistry, 48, 2009
2KY7
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BU of 2ky7 by Molmil
NMR Structural Studies on the Covalent DNA Binding of a Pyrrolobenzodiazepine-Naphthalimide Conjugate
分子名称: 2-{2-[4-(3-{[(11aS)-7-methoxy-5-oxo-2,3,5,10,11,11a-hexahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepin-8-yl]oxy}propyl)piperazin-1-yl]ethyl}-1H-benzo[de]isoquinoline-1,3(2H)-dione, 5'-D(*AP*AP*CP*AP*AP*TP*TP*GP*TP*T)-3'
著者Rettig, M, Langel, W, Kamal, A, Weisz, K.
登録日2010-05-17
公開日2010-06-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR structural studies on the covalent DNA binding of a pyrrolobenzodiazepine-naphthalimide conjugate
Org.Biomol.Chem., 8, 2010
6TC8
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BU of 6tc8 by Molmil
2'-F-arabinoguanosine and 2'-F-riboguanosine modified hybrid type G-quadruplex with V-loop
分子名称: DNA (5'-D(*GP*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*(GFL)P*(GF2)P*GP*GP*AP*CP*GP*GP*G)-3')
著者Haase, L, Weisz, K.
登録日2019-11-05
公開日2020-03-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Switching the type of V-loop in sugar-modified G-quadruplexes through altered fluorine interactions.
Chem.Commun.(Camb.), 56, 2020
6TCG
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BU of 6tcg by Molmil
2'-F-riboguanosine and 2'-F-arabinoguanosine modified G-quadruplex with V-loop and all-syn G-tract
分子名称: DNA (5'-D(*GP*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*(GF2)P*(GFL)P*GP*GP*AP*CP*GP*GP*G)-3')
著者Haase, L, Weisz, K.
登録日2019-11-06
公開日2020-03-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Switching the type of V-loop in sugar-modified G-quadruplexes through altered fluorine interactions.
Chem.Commun.(Camb.), 56, 2020
6RS3
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BU of 6rs3 by Molmil
2'-F-riboguanosine modified G-quadruplex with V-loop
分子名称: F1415
著者Haase, L, Weisz, K.
登録日2019-05-21
公開日2019-11-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Sugar Puckering Drives G-Quadruplex Refolding: Implications for V-Shaped Loops.
Chemistry, 26, 2020
6ZL2
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BU of 6zl2 by Molmil
Structure of a parallel c-Myc modified with 3' duplex stem-loop overhang
分子名称: DNA (36-MER)
著者Vianney, Y.M, Weisz, K.
登録日2020-06-30
公開日2020-10-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Quadruplex-Duplex Junction: A High-Affinity Binding Site for Indoloquinoline Ligands.
Chemistry, 26, 2020
6ZL9
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BU of 6zl9 by Molmil
Structure of a parallel c-Myc modified with 5' duplex stem-loop overhang
分子名称: DNA (35-MER)
著者Vianney, Y.M, Weisz, K.
登録日2020-06-30
公開日2020-10-07
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Quadruplex-Duplex Junction: A High-Affinity Binding Site for Indoloquinoline Ligands.
Chemistry, 26, 2020
6ERL
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BU of 6erl by Molmil
Quadruplex with flipped tetrad formed by the c-myc promoter sequence
分子名称: cmbr-481317
著者Karg, B, Weisz, K.
登録日2017-10-18
公開日2018-06-13
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Loop Length Affects Syn-Anti Conformational Rearrangements in Parallel G-Quadruplexes.
Chemistry, 2018

 

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