1KZA
 
 | | Complex of MBP-C and Man-a13-Man | | Descriptor: | CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN C, ... | | Authors: | Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | | Deposit date: | 2002-02-06 | | Release date: | 2002-07-05 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
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3BCT
 | | THE ARMADILLO REPEAT REGION FROM MURINE BETA-CATENIN | | Descriptor: | BETA-CATENIN, CHLORIDE ION, UREA | | Authors: | Huber, A.H, Nelson, W.J, Weis, W.I. | | Deposit date: | 1997-07-31 | | Release date: | 1997-11-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Three-dimensional structure of the armadillo repeat region of beta-catenin.
Cell(Cambridge,Mass.), 90, 1997
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1KZE
 | | Complex of MBP-C and bivalent Man-terminated glycopeptide | | Descriptor: | CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN C, ... | | Authors: | Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | | Deposit date: | 2002-02-06 | | Release date: | 2002-07-05 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
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1KWX
 | | Rat mannose protein A complexed with b-Me-Fuc. | | Descriptor: | CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN A, ... | | Authors: | Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | | Deposit date: | 2002-01-30 | | Release date: | 2002-07-05 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
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1LVF
 | | syntaxin 6 | | Descriptor: | syntaxin 6 | | Authors: | Misura, K.M.S, Bock, J.B, Gonzalez, L.C, Scheller, R.H, Weis, W.I. | | Deposit date: | 2002-05-28 | | Release date: | 2002-07-17 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Three-dimensional structure of the amino-terminal domain of syntaxin 6, a SNAP-25 C homolog.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1M1E
 | | Beta-catenin armadillo repeat domain bound to ICAT | | Descriptor: | Beta-catenin, ICAT | | Authors: | Daniels, D.L, Weis, W.I. | | Deposit date: | 2002-06-18 | | Release date: | 2002-10-16 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | ICAT inhibits Beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules.
Mol.Cell, 10, 2002
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1IFQ
 | | Sec22b N-terminal domain | | Descriptor: | GLYCEROL, vesicle trafficking protein Sec22b | | Authors: | Gonzalez Jr, L.C, Weis, W.I, Scheller, R.H. | | Deposit date: | 2001-04-13 | | Release date: | 2001-05-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A novel snare N-terminal domain revealed by the crystal structure of Sec22b.
J.Biol.Chem., 276, 2001
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1JTH
 | | Crystal structure and biophysical properties of a complex between the N-terminal region of SNAP25 and the SNARE region of syntaxin 1a | | Descriptor: | SNAP25, syntaxin 1a | | Authors: | Misura, K.M.S, Gonzalez Jr, L.C, May, A.P, Scheller, R.H, Weis, W.I. | | Deposit date: | 2001-08-21 | | Release date: | 2001-11-28 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure and biophysical properties of a complex between the N-terminal SNARE region of SNAP25 and syntaxin 1a.
J.Biol.Chem., 276, 2001
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1EPU
 | | X-RAY crystal structure of neuronal SEC1 from squid | | Descriptor: | S-SEC1 | | Authors: | Bracher, A, Perrakis, A, Dresbach, T, Betz, H, Weissenhorn, W. | | Deposit date: | 2000-03-29 | | Release date: | 2000-08-09 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The X-ray crystal structure of neuronal Sec1 from squid sheds new light on the role of this protein in exocytosis.
Structure Fold.Des., 8, 2000
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1DOV
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1DOW
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1DK8
 | | CRYSTAL STRUCTURE OF THE RGS-HOMOLOGOUS DOMAIN OF AXIN | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, AXIN, GLYCEROL, ... | | Authors: | Spink, K.E, Polakis, P, Weis, W.I. | | Deposit date: | 1999-12-06 | | Release date: | 2000-07-12 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | Structural basis of the Axin-adenomatous polyposis coli interaction.
EMBO J., 19, 2000
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1EGI
 | | STRUCTURE OF A C-TYPE CARBOHYDRATE-RECOGNITION DOMAIN (CRD-4) FROM THE MACROPHAGE MANNOSE RECEPTOR | | Descriptor: | CALCIUM ION, MACROPHAGE MANNOSE RECEPTOR | | Authors: | Feinberg, H, Park-Snyder, S, Kolatkar, A.R, Heise, C.T, Taylor, M.E, Weis, W.I. | | Deposit date: | 2000-02-15 | | Release date: | 2000-08-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of a C-type carbohydrate recognition domain from the macrophage mannose receptor.
J.Biol.Chem., 275, 2000
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1EMU
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2BCT
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3KMB
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3C98
 | | Revised structure of the munc18a-syntaxin1 complex | | Descriptor: | Syntaxin-1A, Syntaxin-binding protein 1 | | Authors: | Hattendorf, D.A, Misura, K.M, Burkhardt, P, Scheller, R.H, Fasshauer, D, Weis, W.I. | | Deposit date: | 2008-02-15 | | Release date: | 2008-03-25 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.601 Å) | | Cite: | Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptide
Embo J., 27, 2008
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3KJ6
 | | Crystal structure of a Methylated beta2 Adrenergic Receptor-Fab complex | | Descriptor: | Beta-2 adrenergic receptor, Fab heavy chain, Fab light chain, ... | | Authors: | Bokoch, M.P, Zou, Y, Rasmussen, S.G.F, Liu, C.W, Nygaard, R, Rosenbaum, D.M, Fung, J.J, Choi, H.-J, Thian, F.S, Kobilka, T.S, Puglisi, J.D, Weis, W.I, Pardo, L, Prosser, S, Mueller, L, Kobilka, B.K. | | Deposit date: | 2009-11-02 | | Release date: | 2010-02-16 | | Last modified: | 2021-10-13 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.
Nature, 463, 2010
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1ES6
 | | CRYSTAL STRUCTURE OF THE MATRIX PROTEIN OF EBOLA VIRUS | | Descriptor: | MATRIX PROTEIN VP40 | | Authors: | Dessen, A, Volchkov, V, Dolnik, O, Klenk, H.-D, Weissenhorn, W. | | Deposit date: | 2000-04-07 | | Release date: | 2000-08-30 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the matrix protein VP40 from Ebola virus.
EMBO J., 19, 2000
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5X7D
 | | Structure of beta2 adrenoceptor bound to carazolol and an intracellular allosteric antagonist | | Descriptor: | (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, 1,4-BUTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Liu, X, Ahn, S, Kahsai, A.W, Meng, K.-C, Latorraca, N.R, Pani, B, Venkatakrishnan, A.J, Masoudi, A, Weis, W.I, Dror, R.O, Chen, X, Lefkowitz, R.J, Kobilka, B.K. | | Deposit date: | 2017-02-25 | | Release date: | 2017-08-16 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.703 Å) | | Cite: | Mechanism of intracellular allosteric beta 2AR antagonist revealed by X-ray crystal structure.
Nature, 548, 2017
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3JQH
 | | Structure of the neck region of the glycan-binding receptor DC-SIGNR | | Descriptor: | C-type lectin domain family 4 member M | | Authors: | Feinberg, H, Tso, C.K.W, Taylor, M.E, Drickamer, K, Weis, W.I. | | Deposit date: | 2009-09-06 | | Release date: | 2009-11-10 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.201 Å) | | Cite: | Segmented helical structure of the neck region of the glycan-binding receptor DC-SIGNR.
J.Mol.Biol., 394, 2009
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2KMB
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3CF2
 | | Structure of P97/vcp in complex with ADP/AMP-PNP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | | Authors: | Davies, J.M, Delabarre, B, Brunger, A.T, Weis, W.I. | | Deposit date: | 2008-03-01 | | Release date: | 2008-04-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change.
Structure, 16, 2008
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3CF3
 | | Structure of P97/vcp in complex with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | | Authors: | Davies, J.M, Delabarre, B, Brunger, A.T, Weis, W.I. | | Deposit date: | 2008-03-01 | | Release date: | 2008-04-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (4.25 Å) | | Cite: | Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change.
Structure, 16, 2008
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3CF1
 | | Structure of P97/vcp in complex with ADP/ADP.alfx | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Transitional endoplasmic reticulum ATPase | | Authors: | Davies, J.M, Delabarre, B, Brunger, A.T, Weis, W.I. | | Deposit date: | 2008-03-01 | | Release date: | 2008-04-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (4.4 Å) | | Cite: | Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change.
Structure, 16, 2008
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