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PDB: 24 件
6L9M
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BU of 6l9m by Molmil
H2-Ld complexed with AH1 peptide
分子名称: H2-Ld, SER-PRO-SER-TYR-VAL-TYR-HIS-GLN-PHE, b2m
著者Wei, P.C, Yin, L.
登録日2019-11-10
公開日2020-11-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer.
Proc.Natl.Acad.Sci.USA, 118, 2021
8IVL
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BU of 8ivl by Molmil
FABP7 complexed with Cholesterol
分子名称: CHOLESTEROL, Fatty acid-binding protein, brain
著者Wei, P.C, Zhao, K, Yin, L.
登録日2023-03-28
公開日2024-02-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Fatty acid-binding proteins 3, 7, and 8 bind cholesterol and facilitate its egress from lysosomes.
J.Cell Biol., 223, 2024
8IVF
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BU of 8ivf by Molmil
FABP7 complexed with 25-HC
分子名称: 25-HYDROXYCHOLESTEROL, Fatty acid-binding protein, brain
著者Wei, P.C, Zhao, K, Yin, L.
登録日2023-03-27
公開日2024-02-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Fatty acid-binding proteins 3, 7, and 8 bind cholesterol and facilitate its egress from lysosomes.
J.Cell Biol., 223, 2024
5YLF
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BU of 5ylf by Molmil
MCR-1 complex with D-glucose
分子名称: Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION, beta-D-glucopyranose
著者Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L.
登録日2017-10-17
公開日2017-11-08
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
5YLC
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BU of 5ylc by Molmil
Crystal Structure of MCR-1 Catalytic Domain
分子名称: Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION
著者Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L.
登録日2017-10-17
公開日2017-11-08
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
5YLE
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BU of 5yle by Molmil
MCR-1 complex with ethanolamine (ETA)
分子名称: ETHANOLAMINE, Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION
著者Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L.
登録日2017-10-17
公開日2017-11-08
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
5XS3
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BU of 5xs3 by Molmil
Crystal structure of HLA Class I antigen
分子名称: Heavy Chain, Light Chain, P
著者Wei, P.C, Yang, Y, Liu, Z.X, Luo, Z.Q, Tu, W.Y, Han, J.Y, Deng, Y.H, Yin, L.
登録日2017-06-12
公開日2017-09-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Characterization of Autoantigen Presentation by HLA-C*06:02 in Psoriasis
J. Invest. Dermatol., 137, 2017
6L9K
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BU of 6l9k by Molmil
H2-Ld a1a2 complexed with A5 peptide
分子名称: H2-Ld a1a2, SER-PRO-SER-TYR-ALA-TYR-HIS-GLN-PHE
著者Wei, P.C, Yin, L.
登録日2019-11-10
公開日2020-11-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer.
Proc.Natl.Acad.Sci.USA, 118, 2021
6L9N
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BU of 6l9n by Molmil
H2-Ld complexed with A5 peptide
分子名称: MHC, SER-PRO-SER-TYR-ALA-TYR-HIS-GLN-PHE, b2m
著者Wei, P.C, Yin, L.
登録日2019-11-10
公開日2020-11-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer.
Proc.Natl.Acad.Sci.USA, 118, 2021
6L9L
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BU of 6l9l by Molmil
1D4 TCR recognition of H2-Ld a1a2 A5 Peptide Complexes
分子名称: H2-Ld a1a2, SER-PRO-SER-TYR-ALA-TYR-HIS-GLN-PHE, T Cell Receptor
著者Wei, P.C, Yin, L.
登録日2019-11-10
公開日2020-11-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.399 Å)
主引用文献Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer.
Proc.Natl.Acad.Sci.USA, 118, 2021
6L9O
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BU of 6l9o by Molmil
Crystal structure of FABP7 apo
分子名称: Fatty acid-binding protein, brain
著者Wei, P.C, Yin, L.
登録日2019-11-10
公開日2020-11-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Crystal structure of FABP7 apo
To Be Published
6BCA
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BU of 6bca by Molmil
A Complex between PH Domain of LbcRhoGEF (AKAP-Lbc) and Activated RhoA Bound to a GTP Analog
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, A-kinase anchor protein 13, MAGNESIUM ION, ...
著者Sternweis, P.C, Chen, Z.
登録日2017-10-20
公開日2017-12-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.995 Å)
主引用文献Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
Data Brief, 17, 2018
6BCB
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BU of 6bcb by Molmil
A Complex between PH Domain of p114RhoGEF and Activated RhoA Bound to a GTP Analog
分子名称: 1,2-ETHANEDIOL, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ...
著者Sternweis, P.C, Chen, Z.
登録日2017-10-20
公開日2017-12-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
Data Brief, 17, 2018
5FMA
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BU of 5fma by Molmil
human Notch 1, EGF 4-7
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Weisshuhn, P.C, Sheppard, D, Taylor, P, Whiteman, P, Lea, S.M, Handford, P.A, Redfield, C.
登録日2015-11-02
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies.
Structure, 24, 2016
5FM9
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BU of 5fm9 by Molmil
human Notch 1, EGF 4-7
分子名称: CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1
著者Weisshuhn, P.C, Sheppard, D, Taylor, P, Whiteman, P, Lea, S.M, Handford, P.A, Redfield, C.
登録日2015-11-02
公開日2016-04-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies.
Structure, 24, 2016
5Z9S
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BU of 5z9s by Molmil
Functional and Structural Characterization of a beta-Glucosidase Involved in Saponin Metabolism from Intestinal Bacteria
分子名称: Glycosyl hydrolase family 3 protein, beta-D-glucopyranose
著者Yan, S, Wei, P.C, Li, J.R.
登録日2018-02-05
公開日2018-03-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Functional and structural characterization of a beta-glucosidase involved in saponin metabolism from intestinal bacteria.
Biochem. Biophys. Res. Commun., 496, 2018
6BC0
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BU of 6bc0 by Molmil
A Complex between PH Domain of p190RhoGEF and Activated RhoA Bound to a GTP Analog
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho guanine nucleotide exchange factor 28, ...
著者Chen, Z, Sternweis, P.C.
登録日2017-10-20
公開日2017-12-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.198 Å)
主引用文献Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
J. Struct. Biol., 202, 2018
6BC1
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BU of 6bc1 by Molmil
A Complex between PH Domain of p190RhoGEF and Activated Rac1 Bound to a GTP Analog
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1, ...
著者Chen, Z, Sternweis, P.C.
登録日2017-10-20
公開日2017-12-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
J. Struct. Biol., 202, 2018
1SHZ
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BU of 1shz by Molmil
Crystal Structure of the p115RhoGEF rgRGS Domain in A Complex with Galpha(13):Galpha(i1) Chimera
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine Nucleotide-Binding Protein Galpha(13):Galpha(i1) Chimera, MAGNESIUM ION, ...
著者Chen, Z, Singer, W.D, Sternweis, P.C, Sprang, S.R.
登録日2004-02-26
公開日2005-01-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure of the p115RhoGEF rgRGS domain-Galpha13/i1 chimera complex suggests convergent evolution of a GTPase activator.
Nat.Struct.Mol.Biol., 12, 2005
3P6A
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BU of 3p6a by Molmil
Crystal Structure of the DH/PH domains of p115-RhoGEF (R399E mutant)
分子名称: Rho guanine nucleotide exchange factor 1
著者Chen, Z, Guo, L, Sprang, S.R, Sternweis, P.C.
登録日2010-10-11
公開日2011-01-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3ODX
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BU of 3odx by Molmil
Crystal Structure of an N-terminally Truncated Linker-DH/PH Domains of p115-RhoGEF
分子名称: Rho guanine nucleotide exchange factor 1
著者Chen, Z, Guo, L, Sprang, S.R, Sternweis, P.C.
登録日2010-08-12
公開日2011-01-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3ODO
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BU of 3odo by Molmil
Crystal Structure of the DH/PH Domains of p115-RhoGEF
分子名称: Rho guanine nucleotide exchange factor 1
著者Chen, Z, Guo, L, Sprang, S.R, Sternweis, P.C.
登録日2010-08-11
公開日2011-01-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3ODW
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BU of 3odw by Molmil
Crystal Structure of the Linker-DH/PH domains of p115-RhoGEF
分子名称: Rho guanine nucleotide exchange factor 1
著者Chen, Z, Guo, L, Sprang, S.R, Sternweis, P.C.
登録日2010-08-11
公開日2011-01-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3KZ1
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BU of 3kz1 by Molmil
Crystal Structure of the Complex of PDZ-RhoGEF DH/PH domains with GTP-gamma-S Activated RhoA
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho guanine nucleotide exchange factor 11, ...
著者Chen, Z, Sternweis, P.C, Sprang, S.R.
登録日2009-12-07
公開日2010-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation.
J.Biol.Chem., 285, 2010

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件を2024-07-17に公開中

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