6HAG
 
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5HQ3
 | | Stable, high-expression variant of human acetylcholinesterase | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acetylcholinesterase, O-ETHYLMETHYLPHOSPHONIC ACID ESTER GROUP | | Authors: | Goldenzweig, A, Goldsmith, M, Hill, S.E, Gertman, O, Laurino, P, Ashani, Y, Dym, O, Albeck, S, Unger, T, Prilusky, J, Lieberman, R.L, Aharoni, A, Silman, I, Sussman, J.L, Tawfik, D.S, Fleishman, S.J. | | Deposit date: | 2016-01-21 | | Release date: | 2016-07-27 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability.
Mol.Cell, 63, 2016
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4WJW
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4KNT
 | | Copper nitrite reductase from Nitrosomonas europaea pH 8.5 | | Descriptor: | COPPER (II) ION, GLYCEROL, Multicopper oxidase type 1 | | Authors: | Rosenzweig, A.C, Lawton, T.L, Sayavedra-Soto, L.A, Arp, D.J. | | Deposit date: | 2013-05-10 | | Release date: | 2013-07-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Characterization of a nitrite reductase involved in nitrifier denitrification.
J.Biol.Chem., 288, 2013
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1VJ9
 | | Urokinase Plasminogen Activator B-Chain-JT464 Complex | | Descriptor: | N-(BENZYLSULFONYL)-L-SERYL-N~1~-{4-[AMINO(IMINO)METHYL]BENZYL}-O-BENZYL-L-SERINAMIDE, SULFATE ION, plasminogen activator, ... | | Authors: | Schweinitz, A, Steinmetzer, T, Banke, I.J, Arlt, M.J.E, Stuerzebecher, A, Schuster, O, Geissler, A, Giersiefen, H, Zeslawska, E, Jacob, U, Kruger, A, Stuerzebecher, J. | | Deposit date: | 2004-02-03 | | Release date: | 2004-06-22 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents
J.Biol.Chem., 279, 2004
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1VJA
 | | Urokinase Plasminogen Activator B-Chain-JT463 Complex | | Descriptor: | N-(BENZYLSULFONYL)SERYL-N~1~-{4-[(Z)-AMINO(IMINO)METHYL]BENZYL}SERINAMIDE, SULFATE ION, plasminogen activator, ... | | Authors: | Schweinitz, A, Steinmetzer, T, Banke, I.J, Arlt, M.J.E, Stuerzebecher, A, Schuster, O, Geissler, A, Giersiefen, H, Zeslawska, E, Jacob, U, Kruger, A, Stuerzebecher, J. | | Deposit date: | 2004-02-03 | | Release date: | 2004-06-22 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents
J.Biol.Chem., 279, 2004
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6DXI
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4KNS
 | | Reduced crystal structure of the Nitrosomonas europaea copper nitrite reductase at pH 6.5 | | Descriptor: | CHLORIDE ION, COPPER (II) ION, GLYCEROL, ... | | Authors: | Rosenzweig, A.C, Lawton, T.L, Sayavedra-Soto, L.A, Arp, D.J. | | Deposit date: | 2013-05-10 | | Release date: | 2013-07-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Characterization of a nitrite reductase involved in nitrifier denitrification.
J.Biol.Chem., 288, 2013
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4KNU
 | | Copper nitrite reductase from Nitrosomonas europaea at pH 6.5 | | Descriptor: | CHLORIDE ION, COPPER (II) ION, GLYCEROL, ... | | Authors: | Rosenzweig, A.C, Lawton, T.L, Sayavedra-Soto, L.A, Arp, D.J. | | Deposit date: | 2013-05-10 | | Release date: | 2013-07-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Characterization of a nitrite reductase involved in nitrifier denitrification.
J.Biol.Chem., 288, 2013
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1MTY
 | | METHANE MONOOXYGENASE HYDROXYLASE FROM METHYLOCOCCUS CAPSULATUS (BATH) | | Descriptor: | FE (III) ION, METHANE MONOOXYGENASE HYDROXYLASE | | Authors: | Rosenzweig, A.C, Nordlund, P, Lippard, S.J, Frederick, C.A. | | Deposit date: | 1996-07-10 | | Release date: | 1997-04-21 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structures of the methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath): implications for substrate gating and component interactions.
Proteins, 29, 1997
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1NP1
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1NTF
 | | Crystal Structure of Cimex Nitrophorin | | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, salivary nitrophorin | | Authors: | Weichsel, A, Maes, E.M, Andersen, J.F, Valenzuela, J.G, Walker, F.A, Montfort, W.R. | | Deposit date: | 2003-01-29 | | Release date: | 2004-03-16 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Heme-assisted S-nitrosation of a proximal thiolate in a nitric oxide transport protein.
Proc.Natl.Acad.Sci.USA, 102, 2005
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4JJI
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1TSD
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1MMO
 | | CRYSTAL STRUCTURE OF A BACTERIAL NON-HAEM IRON HYDROXYLASE THAT CATALYSES THE BIOLOGICAL OXIDATION OF METHANE | | Descriptor: | ACETIC ACID, FE (III) ION, METHANE MONOOXYGENASE HYDROLASE (ALPHA CHAIN), ... | | Authors: | Rosenzweig, A.C, Frederick, C.A, Lippard, S.J, Nordlund, P. | | Deposit date: | 1994-02-22 | | Release date: | 1995-02-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of a bacterial non-haem iron hydroxylase that catalyses the biological oxidation of methane.
Nature, 366, 1993
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1T68
 | | Crystal structure of nitrophorin 2 complex with NO | | Descriptor: | NITRIC OXIDE, Nitrophorin 2, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Weichsel, A, Montfort, W.R. | | Deposit date: | 2004-05-05 | | Release date: | 2005-05-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Conformational change and heme ruffling in nitrophorin 2, a nitric oxide carrier from kissing bug
To be Published
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1TLC
 | | THYMIDYLATE SYNTHASE COMPLEXED WITH DGMP AND FOLATE ANALOG 1843U89 | | Descriptor: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, S)-2-(5(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUINAZOLIN-9-YL)METHYL)AMINO)1-OXO-2-ISOINDOLINYL)GLUTARIC ACID, THYMIDYLATE SYNTHASE | | Authors: | Weichsel, A, Montfort, W.R, Ciesla, J, Maley, F. | | Deposit date: | 1995-03-07 | | Release date: | 1995-06-03 | | Last modified: | 2018-04-18 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Promotion of purine nucleotide binding to thymidylate synthase by a potent folate analogue inhibitor, 1843U89.
Proc.Natl.Acad.Sci.USA, 92, 1995
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4NP1
 | | NITROPHORIN 1 COMPLEX WITH NITRIC OXIDE | | Descriptor: | NITRIC OXIDE, NITROPHORIN 1, PHOSPHATE ION, ... | | Authors: | Weichsel, A, Andersen, J.F, Walker, F.A, Montfort, W.R. | | Deposit date: | 1998-06-26 | | Release date: | 1998-11-11 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Nitric Oxide Binding to the Ferri-and Ferroheme States of Nitrophorin 1, a Reversible No-Binding Heme Protein from the Saliva of the Blood-Sucking Insect, Rhodnius Prolixus
To be Published
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4L0Q
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1ERX
 | | CRYSTAL STRUCTURE OF NITROPHORIN 4 COMPLEXED WITH NO | | Descriptor: | 5,8-DIMETHYL-1,2,3,4-TETRAVINYLPORPHINE-6,7-DIPROPIONIC ACID FERROUS COMPLEX, CITRIC ACID, NITRIC OXIDE, ... | | Authors: | Weichsel, A, Andersen, J.F, Roberts, S.A, Montfort, W.R. | | Deposit date: | 2000-04-06 | | Release date: | 2000-05-03 | | Last modified: | 2018-04-18 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Nitric oxide binding to nitrophorin 4 induces complete distal pocket burial.
Nat.Struct.Biol., 7, 2000
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4GRJ
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4GNW
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1D2U
 | | 1.15 A CRYSTAL STRUCTURE OF NITROPHORIN 4 FROM RHODNIUS PROLIXUS | | Descriptor: | AMMONIA, NITROPHORIN 4, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Weichsel, A, Andersen, J.F, Roberts, S.A, Montfort, W.R. | | Deposit date: | 1999-09-28 | | Release date: | 2001-10-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Ligand-induced heme ruffling and bent no geometry in ultra-high-resolution structures of nitrophorin 4.
Biochemistry, 40, 2001
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1EQD
 | | CRYSTAL STRUCTURE OF NITROPHORIN 4 COMPLEXED WITH CN | | Descriptor: | 5,8-DIMETHYL-1,2,3,4-TETRAVINYLPORPHINE-6,7-DIPROPIONIC ACID FERROUS COMPLEX, CITRIC ACID, CYANIDE ION, ... | | Authors: | Weichsel, A, Andersen, J.F, Roberts, S.A, Montfort, W.R. | | Deposit date: | 2000-04-03 | | Release date: | 2000-05-03 | | Last modified: | 2018-04-18 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Nitric oxide binding to nitrophorin 4 induces complete distal pocket burial.
Nat.Struct.Biol., 7, 2000
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1PEE
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