6F4H
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![BU of 6f4h by Molmil](/molmil-images/mine/6f4h) | Crystal structure of the Drosophila melanogaster SNF/U1-SL2 complex | Descriptor: | CITRATE ANION, U1 small nuclear ribonucleoprotein A, U1-SL2 | Authors: | Weber, G, Holton, N, Hall, K.B, DeKoster, G, Wahl, M.C. | Deposit date: | 2017-11-29 | Release date: | 2018-06-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular principles underlying dual RNA specificity in the Drosophila SNF protein. Nat Commun, 9, 2018
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6F4G
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![BU of 6f4g by Molmil](/molmil-images/mine/6f4g) | 'Crystal structure of the Drosophila melanogaster SNF/U2A'/U2-SL4 complex | Descriptor: | CHLORIDE ION, Probable U2 small nuclear ribonucleoprotein A', SULFATE ION, ... | Authors: | Weber, G, DeKoster, G, Holton, N, Hall, K.B, Wahl, M.C. | Deposit date: | 2017-11-29 | Release date: | 2018-06-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular principles underlying dual RNA specificity in the Drosophila SNF protein. Nat Commun, 9, 2018
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6F4J
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![BU of 6f4j by Molmil](/molmil-images/mine/6f4j) | Crystal structure of Drosophila melanogaster SNF/U2A' complex | Descriptor: | POLYETHYLENE GLYCOL (N=34), Probable U2 small nuclear ribonucleoprotein A', SULFATE ION, ... | Authors: | Weber, G, DeKoster, G, Holton, N, Hall, K.B, Wahl, M.C. | Deposit date: | 2017-11-29 | Release date: | 2018-06-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Molecular principles underlying dual RNA specificity in the Drosophila SNF protein. Nat Commun, 9, 2018
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6F4I
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![BU of 6f4i by Molmil](/molmil-images/mine/6f4i) | Crystal structure of Drosophila melanogaster SNF | Descriptor: | U1 small nuclear ribonucleoprotein A | Authors: | Weber, G, Holton, N, Hall, K.B, DeKoster, G, Wahl, M.C. | Deposit date: | 2017-11-29 | Release date: | 2018-06-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Molecular principles underlying dual RNA specificity in the Drosophila SNF protein. Nat Commun, 9, 2018
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7O4F
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![BU of 7o4f by Molmil](/molmil-images/mine/7o4f) | The DYW domain of A. thaliana OTP86 in its active state | Descriptor: | Pentatricopeptide repeat-containing protein At3g63370, chloroplastic, ZINC ION | Authors: | Weber, G, Palm, G.J, Takenaka, M, Barthel, T, Feiler, C, Weiss, M.S. | Deposit date: | 2021-04-06 | Release date: | 2021-06-30 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | DYW domain structures imply an unusual regulation principle in plant organellar RNA editing catalysis. Nat Catal, 4, 2021
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7O4E
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![BU of 7o4e by Molmil](/molmil-images/mine/7o4e) | The DYW domain of A. thaliana OTP86 in its inactive state | Descriptor: | Pentatricopeptide repeat-containing protein At3g63370, chloroplastic, ZINC ION | Authors: | Weber, G, Palm, G.J, Takenaka, M, Barthel, T, Feiler, C, Weiss, M.S. | Deposit date: | 2021-04-06 | Release date: | 2021-06-30 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | DYW domain structures imply an unusual regulation principle in plant organellar RNA editing catalysis. Nat Catal, 4, 2021
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4ILI
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![BU of 4ili by Molmil](/molmil-images/mine/4ili) | |
4ILJ
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![BU of 4ilj by Molmil](/molmil-images/mine/4ilj) | |
4ILG
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![BU of 4ilg by Molmil](/molmil-images/mine/4ilg) | Crystal structure of Aar2p in complex with the Prp8p RNaseH and Jab1/MPN domains | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 | Authors: | Weber, G, Heroven, A.C, Santos, K.F, Wahl, M.C. | Deposit date: | 2012-12-31 | Release date: | 2013-03-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for dual roles of Aar2p in U5 snRNP assembly. Genes Dev., 27, 2013
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4ILH
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![BU of 4ilh by Molmil](/molmil-images/mine/4ilh) | |
3PGW
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![BU of 3pgw by Molmil](/molmil-images/mine/3pgw) | Crystal structure of human U1 snRNP | Descriptor: | DNA 5'-D(*AP*GP*GP*TP*AP*AP*GP*TP*A)-3', Sm B, Sm G, ... | Authors: | Weber, G, Trowitzsch, S, Kastner, B, Luehrmann, R, Wahl, M.C. | Deposit date: | 2010-11-02 | Release date: | 2010-12-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (4.4 Å) | Cite: | Functional organization of the Sm core in the crystal structure of human U1 snRNP. Embo J., 29, 2010
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3SBS
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![BU of 3sbs by Molmil](/molmil-images/mine/3sbs) | |
3SBT
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![BU of 3sbt by Molmil](/molmil-images/mine/3sbt) | Crystal structure of a Aar2-Prp8 complex | Descriptor: | A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, S-1,2-PROPANEDIOL, ... | Authors: | Weber, G, Santos, K.F, Holton, N, Wahl, M.C. | Deposit date: | 2011-06-06 | Release date: | 2011-07-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | Mechanism for Aar2p function as a U5 snRNP assembly factor. Genes Dev., 25, 2011
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3SBG
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![BU of 3sbg by Molmil](/molmil-images/mine/3sbg) | |
7OS2
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![BU of 7os2 by Molmil](/molmil-images/mine/7os2) | Cryo-EM structure of Brr2 in complex with Jab1/MPN and C9ORF78 | Descriptor: | Pre-mRNA-processing-splicing factor 8, Telomere length and silencing protein 1 homolog, U5 small nuclear ribonucleoprotein 200 kDa helicase | Authors: | Bergfort, A, Hilal, T, Weber, G, Wahl, M.C. | Deposit date: | 2021-06-07 | Release date: | 2022-02-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling. Nucleic Acids Res., 50, 2022
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7OS1
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![BU of 7os1 by Molmil](/molmil-images/mine/7os1) | Cryo-EM structure of Brr2 in complex with Fbp21 | Descriptor: | U5 small nuclear ribonucleoprotein 200 kDa helicase, WW domain-binding protein 4 | Authors: | Bergfort, A, Hilal, T, Weber, G, Wahl, M.C. | Deposit date: | 2021-06-07 | Release date: | 2022-02-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling. Nucleic Acids Res., 50, 2022
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7XG6
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![BU of 7xg6 by Molmil](/molmil-images/mine/7xg6) | Crystal structure of an (R)-selective omega-transaminase mutant from Aspergillus terreus with covalently bound PLP | Descriptor: | omega-transaminase | Authors: | Xiang, C, Wu, S.K, Weber, G, Liu, W.D, Wei, R, Bornscheuer, U.T. | Deposit date: | 2022-04-03 | Release date: | 2022-12-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | A growth selection system for the directed evolution of amine-forming or converting enzymes. Nat Commun, 13, 2022
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7XG5
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![BU of 7xg5 by Molmil](/molmil-images/mine/7xg5) | Crystal structure of an (R)-selective omega-transaminase mutant from Aspergillus terreus with PLP | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, omega-transaminase | Authors: | Xiang, C, Wu, S.K, Weber, G, Liu, W.D, Wei, R, Bornscheuer, U.T. | Deposit date: | 2022-04-03 | Release date: | 2022-12-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | A growth selection system for the directed evolution of amine-forming or converting enzymes. Nat Commun, 13, 2022
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3LSA
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![BU of 3lsa by Molmil](/molmil-images/mine/3lsa) | Padron0.9-OFF (non-fluorescent state) | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Padron0.9, ... | Authors: | Brakemann, T, Weber, G, Trowitzsch, S, Wahl, M.C, Jakobs, S. | Deposit date: | 2010-02-12 | Release date: | 2010-03-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron. J.Biol.Chem., 285, 2010
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3LS3
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![BU of 3ls3 by Molmil](/molmil-images/mine/3ls3) | Padron0.9-ON (fluorescent state) | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Padron0.9, ... | Authors: | Brakemann, T, Weber, G, Trowitzsch, S, Wahl, M.C, Jakobs, S. | Deposit date: | 2010-02-12 | Release date: | 2010-03-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron. J.Biol.Chem., 285, 2010
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4RZ9
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![BU of 4rz9 by Molmil](/molmil-images/mine/4rz9) | Pre-mRNA-splicing factor 38A AS 1-179 | Descriptor: | Pre-mRNA-splicing factor 38A | Authors: | Schuetze, T, Weber, G, Wahl, M.C. | Deposit date: | 2014-12-19 | Release date: | 2015-12-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | The N-terminal domain of the unusual SR protein hPrp38 is an interaction hub in the spliceosome To be Published
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7PJH
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![BU of 7pjh by Molmil](/molmil-images/mine/7pjh) | Crystal structure of the human spliceosomal maturation factor AAR2 bound to the RNAse H domain of PRPF8 | Descriptor: | Pre-mRNA-processing-splicing factor 8, Protein AAR2 homolog | Authors: | Preussner, M, Santos, K, Heroven, A.C, Alles, J, Heyd, F, Wahl, M.C, Weber, G. | Deposit date: | 2021-08-24 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural and functional investigation of the human snRNP assembly factor AAR2 in complex with the RNase H-like domain of PRPF8. Acta Crystallogr D Struct Biol, 78, 2022
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3IPD
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![BU of 3ipd by Molmil](/molmil-images/mine/3ipd) | Helical extension of the neuronal SNARE complex into the membrane, spacegroup I 21 21 21 | Descriptor: | Synaptosomal-associated protein 25, Syntaxin-1A, Vesicle-associated membrane protein 2 | Authors: | Stein, A, Weber, G, Wahl, M.C, Jahn, R. | Deposit date: | 2009-08-17 | Release date: | 2009-09-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (4.8 Å) | Cite: | Helical extension of the neuronal SNARE complex into the membrane Nature, 460, 2009
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6QG9
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![BU of 6qg9 by Molmil](/molmil-images/mine/6qg9) | Crystal structure of Ideonella sakaiensis MHETase | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | Authors: | Palm, G.J, Reisky, L, Boettcher, D, Mueller, H, Michels, E.A.P, Walczak, C, Berndt, L, Weiss, M.S, Bornscheuer, U.T, Weber, G. | Deposit date: | 2019-01-10 | Release date: | 2019-04-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate. Nat Commun, 10, 2019
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6QGA
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![BU of 6qga by Molmil](/molmil-images/mine/6qga) | Crystal structure of Ideonella sakaiensis MHETase bound to the non-hydrolyzable ligand MHETA | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-hydroxyethylcarbamoyl)benzoic acid, CALCIUM ION, ... | Authors: | Palm, G.J, Reisky, L, Boettcher, D, Mueller, H, Michels, E.A.P, Walczak, C, Berndt, L, Weiss, M.S, Bornscheuer, U.T, Weber, G. | Deposit date: | 2019-01-10 | Release date: | 2019-04-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate. Nat Commun, 10, 2019
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