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PDB: 15 件
4UNG
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BU of 4ung by Molmil
Human insulin B26Asn mutant crystal structure
分子名称: INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION
著者Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M.
登録日2014-05-28
公開日2014-10-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex
Acta Crystallogr.,Sect.D, 70, 2014
4UNH
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BU of 4unh by Molmil
Human insulin B26Gly mutant crystal structure
分子名称: INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION
著者Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M.
登録日2014-05-28
公開日2014-10-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex
Acta Crystallogr.,Sect.D, 70, 2014
2WS7
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BU of 2ws7 by Molmil
Semi-synthetic analogue of human insulin ProB26-DTI
分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
著者Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G.
登録日2009-09-03
公開日2010-02-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
2WRU
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BU of 2wru by Molmil
Semi-synthetic highly active analogue of human insulin NMeAlaB26-DTI- NH2
分子名称: ACETATE ION, INSULIN A CHAIN, INSULIN B CHAIN
著者Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G.
登録日2009-09-02
公開日2010-02-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
2WS4
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BU of 2ws4 by Molmil
Semi-synthetic analogue of human insulin ProB26-DTI in monomer form
分子名称: INSULIN A CHAIN, INSULIN B CHAIN
著者Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G.
登録日2009-09-03
公開日2010-02-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
2WS0
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BU of 2ws0 by Molmil
Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 7.5
分子名称: INSULIN A CHAIN, INSULIN B CHAIN
著者Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G.
登録日2009-09-03
公開日2010-02-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
2WRX
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BU of 2wrx by Molmil
Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 3.0
分子名称: INSULIN A CHAIN, INSULIN B CHAIN, SODIUM ION
著者Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G.
登録日2009-09-02
公開日2010-02-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
2WS1
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BU of 2ws1 by Molmil
Semi-synthetic analogue of human insulin NMeTyrB26-insulin in monomer form
分子名称: ACETATE ION, INSULIN A CHAIN, INSULIN B CHAIN
著者Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G.
登録日2009-09-03
公開日2010-02-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
2WRV
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BU of 2wrv by Molmil
Semi-synthetic highly active analogue of human insulin NMeHisB26-DTI- NH2
分子名称: ACETATE ION, INSULIN A CHAIN, INSULIN B CHAIN
著者Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G.
登録日2009-09-02
公開日2010-02-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
2WRW
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BU of 2wrw by Molmil
Semi-synthetic highly active analogue of human insulin D-ProB26-DTI- NH2
分子名称: INSULIN A CHAIN, INSULIN B CHAIN
著者Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G.
登録日2009-09-02
公開日2010-02-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
2WS6
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BU of 2ws6 by Molmil
Semi-synthetic analogue of human insulin NMeTyrB26-insulin in hexamer form
分子名称: CHLORIDE ION, GLYCEROL, INSULIN A CHAIN, ...
著者Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G.
登録日2009-09-03
公開日2010-02-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
4UNE
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BU of 4une by Molmil
Human insulin B26Phe mutant crystal structure
分子名称: INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION
著者Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M.
登録日2014-05-28
公開日2014-10-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex
Acta Crystallogr.,Sect.D, 70, 2014
3ZI3
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BU of 3zi3 by Molmil
Crystal structure of the B24His-insulin - human analogue
分子名称: INSULIN, SULFATE ION
著者Zakova, L, Kletvikova, E, Veverka, V, Lepsik, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M.
登録日2013-01-02
公開日2013-03-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Integrity of the B24 Site in Human Insulin is Important for Hormone Functionality
J.Biol.Chem., 288, 2013
3ZS2
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BU of 3zs2 by Molmil
TyrB25,NMePheB26,LysB28,ProB29-insulin analogue crystal structure
分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
著者Antolikova, E, Zakova, L, Turkenburg, J.P, Watson, C.J, Hanclova, I, Sanda, M, Cooper, A, Kraus, T, Brzozowski, A.M, Jiracek, J.A.
登録日2011-06-21
公開日2011-08-31
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Non-Equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface.
J.Biol.Chem., 286, 2011
3ZQR
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BU of 3zqr by Molmil
NMePheB25 insulin analogue crystal structure
分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
著者Antolikova, E, Zakova, L, Turkenburg, J.P, Watson, C.J, Hanclova, I, Sanda, M, Cooper, A, Kraus, T, Brzozowski, A.M, Jiracek, J.A.
登録日2011-06-10
公開日2011-08-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Non-Equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface.
J.Biol.Chem., 286, 2011

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