3J7L
 
 | | Full virus map of brome mosaic virus | | 分子名称: | Capsid protein | | 著者 | Wang, Z, Hryc, C, Bammes, B, Afonine, P.V, Jakana, J, Chen, D.H, Liu, X, Baker, M.L, Kao, C, Ludtke, S.J, Schmid, M.F, Adams, P.D, Chiu, W. | | 登録日 | 2014-07-18 | | 公開日 | 2014-09-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | An atomic model of brome mosaic virus using direct electron detection and real-space optimization.
Nat Commun, 5, 2014
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7Q48
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7QIO
 | | Homology model of myosin neck domain in skeletal sarcomere | | 分子名称: | Myosin light chain 1/3, skeletal muscle isoform, Myosin regulatory light chain 2, ... | | 著者 | Wang, Z, Grange, M, Pospich, S, Wagner, T, Kho, A.L, Gautel, M, Raunser, S. | | 登録日 | 2021-12-15 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin.
Science, 375, 2022
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7QIN
 | | In situ structure of actomyosin complex in skeletal sarcomere | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Wang, Z, Grange, M, Pospich, S, Wagner, T, Kho, A.L, Gautel, M, Raunser, S. | | 登録日 | 2021-12-15 | | 公開日 | 2022-02-16 | | 最終更新日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | | 主引用文献 | Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin.
Science, 375, 2022
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7Q6L
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7QA2
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3CZR
 | | Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Arylsulfonylpiperazine Inhibitor | | 分子名称: | (2R)-1-[(4-tert-butylphenyl)sulfonyl]-2-methyl-4-(4-nitrophenyl)piperazine, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Corticosteroid 11-beta-dehydrogenase isozyme 1, ... | | 著者 | Wang, Z, Sudom, A, Walker, N.P. | | 登録日 | 2008-04-29 | | 公開日 | 2008-06-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Discovery and Initial SAR of Arylsulfonylpiperazine Inhibitors of 11beta-Hydroxysteroid Dehydrogenase Type 1 (11beta-HSD1)
Bioorg.Med.Chem.Lett., 18, 2008
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3D3E
 | | Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Benzamide Inhibitor | | 分子名称: | Corticosteroid 11-beta-dehydrogenase isozyme 1, N-cyclopropyl-N-(trans-4-pyridin-3-ylcyclohexyl)-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Wang, Z, Sudom, A, Liu, J, Walker, N.P. | | 登録日 | 2008-05-09 | | 公開日 | 2008-07-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Discovery of Novel, Potent Benzamide Inhibitors of 11beta-Hydroxysteroid Dehydrogenase Type 1 (11beta-HSD1) Exhibiting Oral Activity in an Enzyme Inhibition ex Vivo Model
J.Med.Chem., 51, 2008
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7QIM
 | | In situ structure of nebulin bound to actin filament in skeletal sarcomere | | 分子名称: | ACTS protein, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Wang, Z, Grange, M, Pospich, S, Wagner, T, Kho, A.L, Gautel, M, Raunser, S. | | 登録日 | 2021-12-15 | | 公開日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin.
Science, 375, 2022
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3D5Q
 | | Crystal Structure of 11b-HSD1 in Complex with Triazole Inhibitor | | 分子名称: | 3-[1-(4-fluorophenyl)cyclopropyl]-4-(1-methylethyl)-5-[4-(trifluoromethoxy)phenyl]-4H-1,2,4-triazole, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Wang, Z, Liu, J, Sudom, A, Walker, N.P.C. | | 登録日 | 2008-05-16 | | 公開日 | 2008-10-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Distinctive molecular inhibition mechanisms for selective inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.
Bioorg.Med.Chem., 16, 2008
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8JRN
 | | Structure of E6AP-E6 complex in Att1 state | | 分子名称: | Protein E6, Ubiquitin-protein ligase E3A, ZINC ION | | 著者 | Wang, Z, Yu, X. | | 登録日 | 2023-06-17 | | 公開日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural insights into the functional mechanism of the ubiquitin ligase E6AP.
Nat Commun, 15, 2024
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8JRQ
 | | Structure of E6AP-E6 complex in Det1 state | | 分子名称: | Protein E6, Ubiquitin-protein ligase E3A, ZINC ION | | 著者 | Wang, Z, Yu, X. | | 登録日 | 2023-06-17 | | 公開日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (4.15 Å) | | 主引用文献 | Structural insights into the functional mechanism of the ubiquitin ligase E6AP.
Nat Commun, 15, 2024
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8JRP
 | | Structure of E6AP-E6 complex in Att3 state | | 分子名称: | Protein E6, Ubiquitin-protein ligase E3A, ZINC ION | | 著者 | Wang, Z, Yu, X. | | 登録日 | 2023-06-17 | | 公開日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | Structural insights into the functional mechanism of the ubiquitin ligase E6AP.
Nat Commun, 15, 2024
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8JRR
 | | Structure of E6AP-E6 complex in Det2 state | | 分子名称: | Protein E6, Ubiquitin-protein ligase E3A, ZINC ION | | 著者 | Wang, Z, Yu, X. | | 登録日 | 2023-06-17 | | 公開日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (4.35 Å) | | 主引用文献 | Structural insights into the functional mechanism of the ubiquitin ligase E6AP.
Nat Commun, 15, 2024
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8JRO
 | | Structure of E6AP-E6 complex in Att2 state | | 分子名称: | Protein E6, Ubiquitin-protein ligase E3A, ZINC ION | | 著者 | Wang, Z, Yu, X. | | 登録日 | 2023-06-17 | | 公開日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | | 主引用文献 | Structural insights into the functional mechanism of the ubiquitin ligase E6AP.
Nat Commun, 15, 2024
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3D4N
 | | Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Sulfonamide Inhibitor | | 分子名称: | 1-{[(3R)-3-methyl-4-({4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]phenyl}sulfonyl)piperazin-1-yl]methyl}cyclopropanecarboxamide, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Wang, Z, Liu, J, Sudom, A, Walker, N.P. | | 登録日 | 2008-05-14 | | 公開日 | 2008-07-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery of Novel, Potent Benzamide Inhibitors of 11beta-Hydroxysteroid Dehydrogenase Type 1 (11beta-HSD1) Exhibiting Oral Activity in an Enzyme Inhibition ex Vivo Model
J.Med.Chem., 51, 2008
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8TVF
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8TVE
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8TVG
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8TVH
 | | Langya henipavirus postfusion F protein in complex with 4G5 Fab, local refinement of the viral membrane proximal region | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4G5 heavy chain, 4G5 light chain, ... | | 著者 | Wang, Z, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D. | | 登録日 | 2023-08-18 | | 公開日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
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7KH1
 | | Baseplate Complex for Myoviridae Phage XM1 | | 分子名称: | baseplate organization protein, gp11, baseplate stabilizing protein, ... | | 著者 | Wang, Z, Klose, T, Jiang, W, Kuhn, R.J. | | 登録日 | 2020-10-19 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of Vibrio phage XM1, a simple contractile DNA injection machine
Biorxiv, 2021
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7KLN
 | | Myoviridae Phage XM1 Neck Region (12-fold) | | 分子名称: | Head completion protein, gp1, Portal protein | | 著者 | Wang, Z, Klose, T, Jiang, W, Kuhn, R.J. | | 登録日 | 2020-10-30 | | 公開日 | 2021-11-03 | | 最終更新日 | 2022-05-25 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure of Vibrio phage XM1, a simple contractile DNA injection machine
Biorxiv, 2021
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7KJK
 | | The Neck region of Phage XM1 (6-fold symmetry) | | 分子名称: | Collar spike protein, Head completion protein, Tail sheath protein, ... | | 著者 | Wang, Z, Klose, T, Jiang, W, Kuhn, R.J. | | 登録日 | 2020-10-26 | | 公開日 | 2021-11-03 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure of Vibrio phage XM1, a simple contractile DNA injection machine
Biorxiv, 2021
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7KMX
 | | The capsid of Myoviridae Phage XM1 | | 分子名称: | Major capsid protein, Minor capsid protein | | 著者 | Wang, Z, Klose, T, Jiang, W, Kuhn, R.J. | | 登録日 | 2020-11-03 | | 公開日 | 2021-11-10 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of Vibrio phage XM1, a simple contractile DNA injection machine
Biorxiv, 2021
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2FG4
 | | Structure of Human Ferritin L Chain | | 分子名称: | CADMIUM ION, Ferritin light chain | | 著者 | Wang, Z, Li, C, Ellenburg, M, Ruble, J, Ho, J.X, Carter, D.C. | | 登録日 | 2005-12-21 | | 公開日 | 2006-07-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of human ferritin L chain.
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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