3ONA
| The SECRET domain in complex with CX3CL1 | Descriptor: | CX3CL1 protein, Tumour necrosis factor receptor | Authors: | Wang, X.Q, Xue, X.G, Wang, D.L. | Deposit date: | 2010-08-28 | Release date: | 2011-08-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis of chemokine sequestration by CrmD, a poxvirus-encoded tumor necrosis factor receptor Plos Pathog., 7, 2011
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3NFC
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1AQL
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1AKN
| STRUCTURE OF BILE-SALT ACTIVATED LIPASE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BILE-SALT ACTIVATED LIPASE | Authors: | Wang, X, Zhang, X. | Deposit date: | 1997-05-23 | Release date: | 1998-05-27 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The crystal structure of bovine bile salt activated lipase: insights into the bile salt activation mechanism. Structure, 5, 1997
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3OD5
| Crystal structure of active caspase-6 bound with Ac-VEID-CHO | Descriptor: | CACODYLATE ION, Caspase-6, peptide aldehyde inhibitor AC-VEID-CHO | Authors: | Wang, X.-J, Liu, X, Wang, K.-T, Cao, Q, Su, X.-D. | Deposit date: | 2010-08-11 | Release date: | 2010-10-27 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structures of human caspase 6 reveal a new mechanism for intramolecular cleavage self-activation Embo Rep., 11, 2010
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3TKQ
| Crystal structure of full-length human peroxiredoxin 4 with mixed conformation | Descriptor: | Peroxiredoxin-4 | Authors: | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | Deposit date: | 2011-08-28 | Release date: | 2011-10-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4 Biochem.J., 2011
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6LW2
| The N-arylsulfonyl-indole-2-carboxamide-based inhibitors against fructose-1,6-bisphosphatase | Descriptor: | 7-chloranyl-4-[(3-methoxyphenyl)amino]-N-(4-methoxyphenyl)sulfonyl-1-methyl-indole-2-carboxamide, Fructose-1,6-bisphosphatase 1 | Authors: | Wang, X.Y, Zhou, J, Xu, B.L. | Deposit date: | 2020-02-07 | Release date: | 2020-05-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Discovery of N -Arylsulfonyl-Indole-2-Carboxamide Derivatives as Potent, Selective, and Orally Bioavailable Fructose-1,6-Bisphosphatase Inhibitors-Design, Synthesis, In Vivo Glucose Lowering Effects, and X-ray Crystal Complex Analysis. J.Med.Chem., 63, 2020
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6NJD
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3TKR
| Crystal structure of full-length human peroxiredoxin 4 with T118E mutation | Descriptor: | Peroxiredoxin-4 | Authors: | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | Deposit date: | 2011-08-28 | Release date: | 2011-10-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4 Biochem.J., 2011
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6OYL
| The structure of the PP2A B56 subunit KIF4A complex | Descriptor: | Chromosome-associated kinesin KIF4A, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | Authors: | Wang, X, Page, R, Peti, W. | Deposit date: | 2019-05-14 | Release date: | 2020-03-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment. Elife, 9, 2020
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8JUB
| Crystal structure of glutaminase C in complex with compound 27 | Descriptor: | 3-[2-oxidanylidene-2-[[5-[[(3R)-1-pyridazin-3-ylpyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]amino]ethyl]benzoic acid, Glutaminase kidney isoform, mitochondrial | Authors: | Wang, X, Hanyu, S, Tingting, D. | Deposit date: | 2023-06-26 | Release date: | 2023-10-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Targeting the Subpocket Enables the Discovery of Thiadiazole-Pyridazine Derivatives as Glutaminase C Inhibitors. Acs Med.Chem.Lett., 14, 2023
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8JUE
| Crystal structure of glutaminase C in complex with compound 11 | Descriptor: | 2-(3-phenoxyphenyl)-N-[5-[[(3R)-1-pyridazin-3-ylpyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]ethanamide, Glutaminase kidney isoform, mitochondrial | Authors: | Wang, X, Hanyu, S, Tingting, D. | Deposit date: | 2023-06-26 | Release date: | 2023-10-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Targeting the Subpocket Enables the Discovery of Thiadiazole-Pyridazine Derivatives as Glutaminase C Inhibitors. Acs Med.Chem.Lett., 14, 2023
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3O4O
| Crystal structure of an Interleukin-1 receptor complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 beta, ... | Authors: | Wang, X.Q, Wang, D.L, Zhang, S.Y, Li, L, Liu, X, Mei, K.R. | Deposit date: | 2010-07-27 | Release date: | 2010-09-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural insights into the assembly and activation of IL-1beta with its receptors Nat.Immunol., 11, 2010
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8GSD
| Echovirus3 full particle in complex with 6D10 Fab | Descriptor: | Genome polyprotein, Genome polyprotein (Fragment), Heavy chain of 6D10, ... | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-09-06 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural Basis for the Immunogenicity of the C-Terminus of VP1 of Echovirus 3 Revealed by the Binding of a Neutralizing Antibody. Viruses, 14, 2022
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8GSF
| Echovirus3 empty particle in complex with 6D10 Fab (sideling) | Descriptor: | Heavy chain of 6D10, Light chain of 6D10, VP0, ... | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-09-06 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural Basis for the Immunogenicity of the C-Terminus of VP1 of Echovirus 3 Revealed by the Binding of a Neutralizing Antibody. Viruses, 14, 2022
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8GSC
| Echovirus3 A-particle in complex with 6D10 Fab | Descriptor: | Heavy chain of 6D10, Light chain of 6D10, VP1, ... | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-09-06 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural Basis for the Immunogenicity of the C-Terminus of VP1 of Echovirus 3 Revealed by the Binding of a Neutralizing Antibody. Viruses, 14, 2022
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8GSE
| Echovirus3 capsid protein in complex with 6D10 Fab (upright) | Descriptor: | Heavy chain of 6D10, Light chain of 6D10, VP0, ... | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-09-06 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural Basis for the Immunogenicity of the C-Terminus of VP1 of Echovirus 3 Revealed by the Binding of a Neutralizing Antibody. Viruses, 14, 2022
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1PSJ
| ACIDIC PHOSPHOLIPASE A2 FROM AGKISTRODON HALYS PALLAS | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2 | Authors: | Wang, X.Q, Lin, Z.J. | Deposit date: | 1995-05-24 | Release date: | 1996-07-11 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of an acidic phospholipase A2 from the venom of Agkistrodon halys pallas at 2.0 A resolution. J.Mol.Biol., 255, 1996
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5J8V
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1M8W
| CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE1-19 RNA | Descriptor: | 5'-R(P*UP*GP*UP*AP*UP*AP*U)-3', 5'-R(P*UP*GP*UP*CP*CP*AP*G)-3', 5'-R(P*UP*UP*GP*UP*AP*UP*AP*U)-3', ... | Authors: | Wang, X, McLachlan, J, Zamore, P.D, Hall, T.M.T. | Deposit date: | 2002-07-26 | Release date: | 2002-09-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | MODULAR RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY DOMAIN CELL(CAMBRIDGE,MASS.), 110, 2002
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1M8Y
| CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE2-10 RNA | Descriptor: | 5'-R(P*AP*UP*UP*GP*UP*AP*CP*AP*UP*A)-3', Pumilio 1 | Authors: | Wang, X, McLachlan, J, Zamore, P.D, Hall, T.M.T. | Deposit date: | 2002-07-26 | Release date: | 2002-09-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | MODULAR RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY DOMAIN CELL(CAMBRIDGE,MASS.), 110, 2002
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1M8Z
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1M8X
| CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE1-14 RNA | Descriptor: | 5'-R(P*UP*GP*UP*AP*UP*AP*U)-3', 5'-R(P*UP*UP*GP*UP*AP*UP*AP*U)-3', Pumilio 1 | Authors: | Wang, X, McLachlan, J, Zamore, P.D, Hall, T.M.T. | Deposit date: | 2002-07-26 | Release date: | 2002-09-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | MODULAR RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY DOMAIN CELL(CAMBRIDGE,MASS.), 110, 2002
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7MIZ
| Atomic structure of cortical microtubule from Toxoplasma gondii | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Wang, X, Brown, A, Sibley, L.D, Zhang, R. | Deposit date: | 2021-04-18 | Release date: | 2021-06-02 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structure of cortical microtubules from human parasite Toxoplasma gondii identifies their microtubule inner proteins. Nat Commun, 12, 2021
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5IL1
| Crystal structure of SAM-bound METTL3-METTL14 complex | Descriptor: | 1,2-ETHANEDIOL, METTL14, METTL3, ... | Authors: | Wang, X, Guan, Z, Zou, T, Yin, P. | Deposit date: | 2016-03-04 | Release date: | 2016-05-25 | Last modified: | 2016-06-29 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Structural basis of N6-adenosine methylation by the METTL3-METTL14 complex Nature, 534, 2016
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