7FCH
 
 | | IL-18Rbeta TIR domain | | Descriptor: | Interleukin-18 receptor accessory protein | | Authors: | Wang, X, Zhou, J. | | Deposit date: | 2021-07-14 | | Release date: | 2022-07-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.883 Å) | | Cite: | Structural basis of the IL-1 receptor TIR domain-mediated IL-1 signaling
Iscience, 25, 2022
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7FCL
 | | Zebrafish SIGIRR TIR domain | | Descriptor: | SIGIRR protein | | Authors: | Wang, X, Zhou, J. | | Deposit date: | 2021-07-15 | | Release date: | 2022-07-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.04 Å) | | Cite: | Structural basis of the IL-1 receptor TIR domain-mediated IL-1 signaling
Iscience, 25, 2022
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6LGZ
 | | Crystal structure of a cysteine-pair mutant (P10C-S291C) of a bacterial bile acid transporter in an inward-facing state complexed with sulfate | | Descriptor: | 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, SULFATE ION, Transporter, ... | | Authors: | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | | Deposit date: | 2019-12-06 | | Release date: | 2020-12-09 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.428 Å) | | Cite: | Substrate binding in the bile acid transporter ASBT Yf from Yersinia frederiksenii.
Acta Crystallogr D Struct Biol, 77, 2021
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6LH1
 | | Crystal structure of a cysteine-pair mutant (Y113C-P190C) of a bacterial bile acid transporter trapped in an outward-facing conformation | | Descriptor: | 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CITRIC ACID, Transporter, ... | | Authors: | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | | Deposit date: | 2019-12-06 | | Release date: | 2020-12-09 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.861 Å) | | Cite: | An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter.
Acta Crystallogr D Struct Biol, 77, 2021
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6LGV
 | | Crystal structure of a cysteine-pair mutant (P10C-S291C) of a bacterial bile acid transporter in an inward-facing state complexed with citrate | | Descriptor: | 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CITRIC ACID, Transporter, ... | | Authors: | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | | Deposit date: | 2019-12-06 | | Release date: | 2020-12-09 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.847 Å) | | Cite: | Substrate binding in the bile acid transporter ASBT Yf from Yersinia frederiksenii.
Acta Crystallogr D Struct Biol, 77, 2021
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7CYH
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6M4X
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6M4Z
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2KJK
 | | Solution structure of the second domain of the listeria protein Lin2157, Northeast Structural Genomics Consortium target Lkr136b | | Descriptor: | Lin2157 protein | | Authors: | Wang, X, Hamilton, K, Xiao, R.H, Lee, D, Ciccosanti, C.H, Nair, R, Rost, B, Acton, T.B, Swapna, G, Everett, J.K, Montelione, G.T, Prestegard, J.H, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-05-29 | | Release date: | 2009-07-07 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of Lkr136b
To be Published
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2P6V
 | | Structure of TAFH domain of the human TAF4 subunit of TFIID | | Descriptor: | SULFATE ION, Transcription initiation factor TFIID subunit 4 | | Authors: | Wang, X, Truckses, D.M, Takada, S, Matsumura, T, Tanese, N, Jacobson, R.H. | | Deposit date: | 2007-03-19 | | Release date: | 2007-05-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Conserved region I of human coactivator TAF4 binds to a short hydrophobic motif present in transcriptional regulators.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2GMG
 | | Solution NMR Structure of protein PF0610 from Pyrococcus furiosus, Northeast Structural Genomics Consortium Target PfG3 | | Descriptor: | hypothetical protein Pf0610 | | Authors: | Wang, X, Lee, H.S, Adams, M.W, Northeast Structural Genomics Consortium (NESG), Montelione, G.T, Prestegard, J.H. | | Deposit date: | 2006-04-06 | | Release date: | 2006-11-28 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | PF0610, a novel winged helix-turn-helix variant possessing a rubredoxin-like Zn ribbon motif from the hyperthermophilic archaeon, Pyrococcus furiosus.
Biochemistry, 46, 2007
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2JZC
 | | NMR solution structure of ALG13: The sugar donor subunit of a yeast N-acetylglucosamine transferase. Northeast Structural Genomics Consortium target YG1 | | Descriptor: | UDP-N-acetylglucosamine transferase subunit ALG13 | | Authors: | Wang, X, Weldeghorghis, T, Zhang, G, Imepriali, B, Montelione, G.T, Prestegard, J.H, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-01-04 | | Release date: | 2008-02-19 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution structure of Alg13: the sugar donor subunit of a yeast N-acetylglucosamine transferase.
Structure, 16, 2008
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7VFX
 | | The structure of Formyl Peptide Receptor 1 in complex with Gi and peptide agonist fMIFL | | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Wang, X.K, Chen, G, Liao, Q.W, Du, Y, Hu, H.L, Ye, D.Q. | | Deposit date: | 2021-09-14 | | Release date: | 2022-09-21 | | Last modified: | 2022-12-07 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns.
Nat Commun, 13, 2022
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5XGL
 | | Co-crystal structure of Ac-AChBPP in complex with alpha-conotoxin LvIA | | Descriptor: | Alpha-conotoxin LvIA, Soluble acetylcholine receptor | | Authors: | Wang, X.Q, Xu, M.Y, Luo, S.L, Zhu, X.P. | | Deposit date: | 2017-04-14 | | Release date: | 2018-06-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.439 Å) | | Cite: | The crystal structure of Ac-AChBP in complex with alpha-conotoxin LvIA reveals the mechanism of its selectivity towards different nAChR subtypes
Protein Cell, 8, 2017
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7FD3
 | | IL-1RAPL2 TIR domain | | Descriptor: | X-linked interleukin-1 receptor accessory protein-like 2 | | Authors: | Wang, X, Zhou, J. | | Deposit date: | 2021-07-15 | | Release date: | 2022-07-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | Structural basis of the IL-1 receptor TIR domain-mediated IL-1 signaling
Iscience, 25, 2022
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6L77
 | | Crystal structure of MS5 from Brassica napus | | Descriptor: | MS5a | | Authors: | Wang, X, Guan, Z.Y, Yin, P. | | Deposit date: | 2019-10-31 | | Release date: | 2020-06-03 | | Last modified: | 2020-12-09 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural analysis of the meiosis-related protein MS5 reveals non-canonical papain enhancement by cystatin-like folds.
Febs Lett., 594, 2020
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8I3W
 | | BANAL-20-236 Spike trimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Wang, X, Xu, G. | | Deposit date: | 2023-01-18 | | Release date: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | The selective effect of fecal-oral transmission on the S proteins of bat SARS-CoV-2 related coronaviruses in favor of stability over infectivity
To Be Published
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2GYZ
 | | Crystal structure of human artemin | | Descriptor: | neurotrophic factor artemin isoform 3 | | Authors: | Wang, X.Q, Garcia, K.C. | | Deposit date: | 2006-05-10 | | Release date: | 2006-06-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Structure of Artemin Complexed with Its Receptor GFRalpha3: Convergent Recognition of Glial Cell Line-Derived Neurotrophic Factors.
Structure, 14, 2006
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2K2R
 | | The NMR structure of alpha-parvin CH2/paxillin LD1 complex | | Descriptor: | Alpha-parvin, Paxillin | | Authors: | Wang, X, Fukuda, K, Byeon, I, Velyvis, A, Wu, C, Gronenborn, A, Qin, J. | | Deposit date: | 2008-04-10 | | Release date: | 2008-05-27 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | The Structure of {alpha}-Parvin CH2-Paxillin LD1 Complex Reveals a Novel Modular Recognition for Focal Adhesion Assembly.
J.Biol.Chem., 283, 2008
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2LQU
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7VHN
 | | Spike of SARS-CoV-2 spike protein(1 up) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Wang, X. | | Deposit date: | 2021-09-22 | | Release date: | 2022-12-07 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Spike of SARS-CoV-2 spike protein(1 up)
To Be Published
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7CN8
 | | Cryo-EM structure of PCoV_GX spike glycoprotein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein, ... | | Authors: | Wang, X, Yu, J, Zhang, S, Qiao, S, Zeng, J, Tian, L. | | Deposit date: | 2020-07-30 | | Release date: | 2021-03-03 | | Last modified: | 2021-03-24 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution.
Nat Commun, 12, 2021
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7WHH
 | | Crystal structure of SARS-CoV-2 omicron RBD and human ACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Processed angiotensin-converting enzyme 2, ... | | Authors: | Wang, X.Q, Lan, J. | | Deposit date: | 2021-12-30 | | Release date: | 2022-06-01 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of SARS-CoV-2 omicron RBD and human ACE2
To Be Published
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7CN4
 | | Cryo-EM structure of bat RaTG13 spike glycoprotein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Wang, X, Zhang, S, Qiao, S, Yu, J, Zeng, J, Tian, L. | | Deposit date: | 2020-07-30 | | Release date: | 2021-03-03 | | Last modified: | 2021-03-24 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution.
Nat Commun, 12, 2021
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7DH6
 | | Crystal structure of PLRG1 | | Descriptor: | CALCIUM ION, NICKEL (II) ION, Pleiotropic regulator 1, ... | | Authors: | Wang, X, Xu, C. | | Deposit date: | 2020-11-13 | | Release date: | 2020-12-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.584 Å) | | Cite: | Crystal structure of the WD40 domain of human PLRG1.
Biochem.Biophys.Res.Commun., 534, 2021
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