6LH1

Crystal structure of a cysteine-pair mutant (Y113C-P190C) of a bacterial bile acid transporter trapped in an outward-facing conformation

Summary for 6LH1

Entry DOI	10.2210/pdb6lh1/pdb
Related	7CYG 7CYK
Descriptor	Transporter, sodium/bile acid symporter family, CITRIC ACID, 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... (4 entities in total)
Functional Keywords	bile acid transporter, asbt, ntcp, slc10, transport protein
Biological source	Yersinia frederiksenii
Total number of polymer chains	1
Total formula weight	34217.01
Authors	Wang, X.,Lyu, Y.,Ji, Y.,Sun, Z.,Zhou, X. (deposition date: 2019-12-06, release date: 2020-12-09, Last modification date: 2023-11-22)
Primary citation	Wang, X.,Lyu, Y.,Ji, Y.,Sun, Z.,Zhou, X. An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter. Acta Crystallogr D Struct Biol, 77:108-116, 2021 Cited by PubMed: 33404530 DOI: 10.1107/S205979832001517X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.861 Å)

Structure validation