5MGH
 
 | | Crystal structure of pathogenic mutants of human mitochodnrial PheRS | | Descriptor: | PHENYLALANINE, Phenylalanine--tRNA ligase, mitochondrial | | Authors: | Kartvelishvili, E, Tworowski, D, Vernon, H, Chrzanowska-Lightowlers, Z, Moor, N, Wang, J, Wong, L.-J, Safro, M. | | Deposit date: | 2016-11-21 | | Release date: | 2017-05-03 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Kinetic and structural changes in HsmtPheRS, induced by pathogenic mutations in human FARS2.
Protein Sci., 26, 2017
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8GHS
 | | Empty HBV Cp183 capsid with importin-beta, subparticle reconstruction at 2-fold location | | Descriptor: | Capsid protein | | Authors: | Kim, C, Schlicksup, C.J, Hadden-Perilla, J.A, Wang, J.C.-Y, Zlotnick, A. | | Deposit date: | 2023-03-10 | | Release date: | 2023-08-09 | | Last modified: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structure of the Hepatitis B virus capsid quasi-6-fold with a trapped C-terminal domain reveals capsid movements associated with domain exit.
J.Biol.Chem., 299, 2023
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5NEF
 | | The structure of the G. violaceus guanidine II riboswitch P1 stem-loop with guanidine | | Descriptor: | GUANIDINE, RNA (5'-R(*GP*GP*UP*GP*GP*GP*GP*AP*CP*GP*AP*CP*CP*CP*CP*AP*(CBV)P*C)-3'), SODIUM ION, ... | | Authors: | Huang, L, Wang, J, Lilley, D.M.J. | | Deposit date: | 2017-03-10 | | Release date: | 2017-06-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | The Structure of the Guanidine-II Riboswitch.
Cell Chem Biol, 24, 2017
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5NDH
 | | The structure of the G. violaceus guanidine II riboswitch P2 stem-loop | | Descriptor: | GUANIDINE, MAGNESIUM ION, RNA (5'-R(*GP*(CBV)P*GP*GP*GP*GP*AP*CP*GP*AP*CP*CP*CP*CP*GP*C)-3'), ... | | Authors: | Huang, L, Wang, J, Lilley, D.M.J. | | Deposit date: | 2017-03-08 | | Release date: | 2017-05-31 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | The Structure of the Guanidine-II Riboswitch.
Cell Chem Biol, 24, 2017
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5JJA
 | | Crystal structure of a PP2A B56gamma/BubR1 complex | | Descriptor: | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | | Authors: | Wang, Z, Wang, J, Rao, Z, Xu, W. | | Deposit date: | 2016-04-22 | | Release date: | 2016-07-13 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Crystal structure of a PP2A B56-BubR1 complex and its implications for PP2A substrate recruitment and localization.
Protein Cell, 7, 2016
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4YR8
 | | Crystal structure of JNK in complex with a regulator protein | | Descriptor: | CHLORIDE ION, Dual specificity protein phosphatase 16, Mitogen-activated protein kinase 8 | | Authors: | Liu, X, Wang, J, Wu, J.W, Wang, Z.X. | | Deposit date: | 2015-03-14 | | Release date: | 2016-03-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation.
Nat Commun, 7, 2016
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7TUL
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7TUK
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5NOM
 | | The structure of the G. violaceus guanidine II riboswitch P1 stem-loop with guanidine | | Descriptor: | GUANIDINE, RNA (5'-R(*GP*GP*UP*GP*GP*GP*GP*AP*CP*GP*AP*CP*CP*CP*CP*AP*(CBV)P*C)-3'), SODIUM ION, ... | | Authors: | Huang, L, Wang, J, Lilley, D.M.J. | | Deposit date: | 2017-04-12 | | Release date: | 2017-05-31 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | The Structure of the Guanidine-II Riboswitch.
Cell Chem Biol, 24, 2017
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5NDI
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1QU3
 | | INSIGHTS INTO EDITING FROM AN ILE-TRNA SYNTHETASE STRUCTURE WITH TRNA(ILE) AND MUPIROCIN | | Descriptor: | ISOLEUCYL-TRNA, ISOLEUCYL-TRNA SYNTHETASE, MUPIROCIN, ... | | Authors: | Silvian, L.F, Wang, J, Steitz, T.A. | | Deposit date: | 1999-07-06 | | Release date: | 1999-08-31 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin.
Science, 285, 1999
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4TZ7
 | | Crystal structure of type I phosphatidylinositol 4-phosphate 5-kinase alpha from Zebrafish | | Descriptor: | Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | | Authors: | Hu, J, Qin, Y, Wang, J, Li, L, Wu, D, Ha, Y. | | Deposit date: | 2014-07-09 | | Release date: | 2015-09-02 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.31 Å) | | Cite: | Resolution of structure of PIP5K1A reveals molecular mechanism for its regulation by dimerization and dishevelled.
Nat Commun, 6, 2015
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6Z71
 | | Structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state | | Descriptor: | Aq128 | | Authors: | Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H. | | Deposit date: | 2020-05-29 | | Release date: | 2021-12-01 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | The structure of the Aquifex aeolicus MATE family multidrug resistance transporter and sequence comparisons suggest the existence of a new subfamily.
Proc.Natl.Acad.Sci.USA, 118, 2021
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1IH7
 | | High-Resolution Structure of Apo RB69 DNA Polymerase | | Descriptor: | DNA POLYMERASE, GUANOSINE, POTASSIUM ION | | Authors: | Franklin, M.C, Wang, J, Steitz, T.A. | | Deposit date: | 2001-04-18 | | Release date: | 2001-06-13 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Structure of the Replicating Complex of a Pol alpha Family DNA Polymerase
Cell(Cambridge,Mass.), 105, 2001
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4CSU
 | | Cryo-EM structures of the 50S ribosome subunit bound with ObgE | | Descriptor: | 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L11, ... | | Authors: | Feng, B, Mandava, C.S, Guo, Q, Wang, J, Cao, W, Li, N, Zhang, Y, Zhang, Y, Wang, Z, Wu, J, Sanyal, S, Lei, J, Gao, N. | | Deposit date: | 2014-03-10 | | Release date: | 2014-06-04 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (5.5 Å) | | Cite: | Structural and Functional Insights Into the Mode of Action of a Universally Conserved Obg Gtpase.
Plos Biol., 12, 2014
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4D90
 | | Crystal Structure of Del-1 EGF domains | | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Chen, Q, Schurpf, T, Springer, T, Wang, J. | | Deposit date: | 2012-01-11 | | Release date: | 2012-05-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.601 Å) | | Cite: | The RGD finger of Del-1 is a unique structural feature critical for integrin binding.
Faseb J., 26, 2012
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3ID4
 | | Crystal Structure of RseP PDZ2 domain fused GKASPV peptide | | Descriptor: | Regulator of sigma E protease | | Authors: | Li, X, Wang, B, Feng, L, Wang, J, Shi, Y. | | Deposit date: | 2009-07-20 | | Release date: | 2009-08-11 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.604 Å) | | Cite: | Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage
Proc.Natl.Acad.Sci.USA, 106, 2009
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5C4W
 | | Crystal structure of coxsackievirus A16 | | Descriptor: | CHLORIDE ION, POTASSIUM ION, SODIUM ION, ... | | Authors: | Ren, J, Wang, X, Zhu, L, Hu, Z, Gao, Q, Yang, P, Li, X, Wang, J, Shen, X, Fry, E.E, Rao, Z, Stuart, D.I. | | Deposit date: | 2015-06-18 | | Release date: | 2015-08-26 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity.
J.Virol., 89, 2015
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5C9A
 | | Crystal structure of empty coxsackievirus A16 particle | | Descriptor: | CHLORIDE ION, POTASSIUM ION, SPHINGOSINE, ... | | Authors: | Ren, J, Wang, X, Zhu, L, Hu, Z, Gao, Q, Yang, P, Li, X, Wang, J, Shen, X, Fry, E.E, Rao, Z, Stuart, D.I. | | Deposit date: | 2015-06-26 | | Release date: | 2015-08-26 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity.
J.Virol., 89, 2015
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3ID1
 | | Crystal Structure of RseP PDZ1 domain | | Descriptor: | Regulator of sigma E protease | | Authors: | Li, X, Wang, B, Feng, L, Wang, J, Shi, Y. | | Deposit date: | 2009-07-20 | | Release date: | 2009-08-11 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage
Proc.Natl.Acad.Sci.USA, 106, 2009
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3ID3
 | | Crystal Structure of RseP PDZ2 I304A domain | | Descriptor: | Regulator of sigma E protease | | Authors: | Li, X, Wang, B, Feng, L, Wang, J, Shi, Y. | | Deposit date: | 2009-07-20 | | Release date: | 2009-08-11 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage
Proc.Natl.Acad.Sci.USA, 106, 2009
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5MV1
 | | Crystal structure of the E protein of the Japanese encephalitis virulent virus | | Descriptor: | E protein | | Authors: | Liu, X, Zhao, X, Na, R, Li, L, Warkentin, E, Witt, J, Lu, X, Wei, Y, Peng, G, Li, Y, Wang, J. | | Deposit date: | 2017-01-14 | | Release date: | 2018-05-23 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism.
Protein Cell, 10, 2019
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8D8O
 | | Cryo-EM structure of substrate unbound PAPP-A | | Descriptor: | Pappalysin-1, ZINC ION | | Authors: | Judge, R.A, Jain, R, Hao, Q, Ouch, C, Sridar, J, Smith, C.L, Wang, J.C.K, Eaton, D. | | Deposit date: | 2022-06-08 | | Release date: | 2022-09-28 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition
Nat Commun, 13, 2022
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3KID
 | | The Crystal Structures of 2-Aminobenzothiazole-based Inhibitors in Complexes with Urokinase-type Plasminogen Activator | | Descriptor: | Urokinase-type plasminogen activator, ethyl 2-amino-1,3-benzothiazole-6-carboxylate | | Authors: | Jiang, L.-G, Yu, H.Y, Yuan, C, Wang, J.D, Chen, L.Q, Meehan, E.J, Huang, Z.-X, Huang, M.-D. | | Deposit date: | 2009-11-01 | | Release date: | 2009-12-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Crystal Structures of 2-Aminobenzothiazole-based Inhibitors in Complexes with Urokinase-type Plasminogen Activator
CHIN.J.STRUCT.CHEM., 28, 2009
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3K3O
 | | Crystal structure of the catalytic core domain of human PHF8 complexed with alpha-ketoglutarate | | Descriptor: | 2-OXOGLUTARIC ACID, FE (II) ION, PHD finger protein 8 | | Authors: | Yu, L, Wang, Y, Huang, S, Wang, J, Deng, Z, Wu, W, Gong, W, Chen, Z. | | Deposit date: | 2009-10-03 | | Release date: | 2010-01-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural insights into a novel histone demethylase PHF8
Cell Res., 20, 2010
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