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PDB: 683 results

4EGL
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BU of 4egl by Molmil
Crystal structure of two tandem RNA recognition motifs of Human antigen R
Descriptor: ELAV-like protein 1, GLYCEROL, SULFATE ION
Authors:Wang, H, Zeng, F, Liu, H, Teng, M, Li, X.
Deposit date:2012-03-31
Release date:2012-05-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of two tandem RNA recognition motifs of Human antigen R
To be Published
4QBR
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BU of 4qbr by Molmil
Crystal structure of DNMT3a ADD domain G550D mutant bound to H3 peptide
Descriptor: DNA (cytosine-5)-methyltransferase 3A, Histone H3, ZINC ION
Authors:Wang, H, Li, H.
Deposit date:2014-05-08
Release date:2015-05-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs
To be Published
3WOH
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BU of 3woh by Molmil
Structure of Ketoreductase SiaM from Streptomyces sp. A7248
Descriptor: SiaM
Authors:Wang, H, Zhang, H.
Deposit date:2013-12-29
Release date:2014-08-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insight into the tetramerization of an iterative ketoreductase siam through aromatic residues in the interfaces
Plos One, 9, 2014
3O47
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BU of 3o47 by Molmil
Crystal structure of ARFGAP1-ARF1 fusion protein
Descriptor: ADP-ribosylation factor GTPase-activating protein 1, ADP-ribosylation factor 1, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Wang, H, Tong, Y, Nedyalkova, L, Tempel, W, Guan, X, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2010-07-26
Release date:2010-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of ARFGAP1-ARF1 fusion protein
to be published
4MM8
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BU of 4mm8 by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with (R)-fluoxetine
Descriptor: (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MMF
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BU of 4mmf by Molmil
Crystal structure of LeuBAT (delta5 mutant) in complex with mazindol
Descriptor: (5R)-5-(4-chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol, SODIUM ION, Transporter, ...
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MM4
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BU of 4mm4 by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with paroxetine
Descriptor: CHLORIDE ION, Paroxetine, SODIUM ION, ...
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.886 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MMA
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BU of 4mma by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with clomipramine
Descriptor: 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
8X0U
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BU of 8x0u by Molmil
Crystal structure of cupin-like fold protein StrC from Stachybotrys sp.g12
Descriptor: Cupin conserved barrel domain protein
Authors:Wang, H, Wang, W.G.
Deposit date:2023-11-06
Release date:2024-09-11
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural and Computational Insights into the Noncanonical Aromatization in Fungal Polyketide Biosynthesis
Acs Catalysis, 14, 2024
8X0V
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BU of 8x0v by Molmil
Crystal structure of cupin-like fold protein StrC in complex with substrate analogue from Stachybotrys sp.g12
Descriptor: (5~{R})-2-(hydroxymethyl)-3-[(~{E})-non-3-enyl]-5-oxidanyl-cyclohex-2-en-1-one, Cupin conserved barrel domain protein
Authors:Wang, H, Wang, W.G.
Deposit date:2023-11-06
Release date:2024-09-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and Computational Insights into the Noncanonical Aromatization in Fungal Polyketide Biosynthesis
Acs Catalysis, 14, 2024
4MM7
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BU of 4mm7 by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with desvenlafaxine
Descriptor: 4-[(1R)-2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MMC
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BU of 4mmc by Molmil
Crystal structure of LeuBAT (delta6 mutant) in complex with desvenlafaxine
Descriptor: 4-[(1R)-2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol, SODIUM ION, Transporter, ...
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MM6
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BU of 4mm6 by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with (S)-duloxetine
Descriptor: (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MME
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BU of 4mme by Molmil
Crystal structure of LeuBAT (delta6 mutant) in complex with mazindol
Descriptor: (5R)-5-(4-chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol, SODIUM ION, Transporter, ...
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4ZYO
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BU of 4zyo by Molmil
Crystal Structure of Human Integral Membrane Stearoyl-CoA Desaturase with Substrate
Descriptor: Acyl-CoA desaturase, DODECYL-BETA-D-MALTOSIDE, STEAROYL-COENZYME A, ...
Authors:Wang, H, Klein, M.G, Lane, W, Snell, G, Levin, I, Li, K, Zou, H, Sang, B.-C.
Deposit date:2015-05-21
Release date:2015-06-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Crystal structure of human stearoyl-coenzyme A desaturase in complex with substrate.
Nat.Struct.Mol.Biol., 22, 2015
4MMD
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BU of 4mmd by Molmil
Crystal structure of LeuBAT (delta6 mutant) in complex with (S)-duloxetine
Descriptor: (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine, SODIUM ION, Transporter, ...
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
3PFN
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BU of 3pfn by Molmil
Crystal Structure of human NAD kinase
Descriptor: NAD kinase, UNKNOWN ATOM OR ION
Authors:Wang, H, Tempel, W, Wernimont, A.K, Tong, Y, Guan, X, Shen, Y, Li, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2010-10-28
Release date:2010-11-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of human NAD kinase
to be published
4MM9
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BU of 4mm9 by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with fluvoxamine
Descriptor: Fluvoxamine, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MM5
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BU of 4mm5 by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with sertraline
Descriptor: (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MMB
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BU of 4mmb by Molmil
Crystal structure of LeuBAT (delta6 mutant) in complex with sertraline
Descriptor: (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, SODIUM ION, Transporter, ...
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
3Q3J
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BU of 3q3j by Molmil
Crystal structure of plexin A2 RBD in complex with Rnd1
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Plexin-A2, ...
Authors:Wang, H, Tempel, W, Tong, Y, Guan, X, Shen, L, Buren, L, Zhang, N, Wernimont, A.K, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2010-12-21
Release date:2011-01-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.971 Å)
Cite:Crystal structure of plexin A2 RBD in complex with Rnd1
to be published
4ED5
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BU of 4ed5 by Molmil
Crystal structure of the two N-terminal RRM domains of HuR complexed with RNA
Descriptor: 1,2-ETHANEDIOL, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, 5'-R(*A*UP*UP*UP*UP*UP*AP*UP*UP*UP*U)-3', ...
Authors:Wang, H, Zeng, F, Liu, Q, Niu, L, Teng, M, Li, X.
Deposit date:2012-03-27
Release date:2012-05-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of the ARE-binding domains of Hu antigen R (HuR) undergoes conformational changes during RNA binding.
Acta Crystallogr.,Sect.D, 69, 2013
7MOJ
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BU of 7moj by Molmil
Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with a metaphosphate intermediate
Descriptor: PHOSPHITE ION, Tyrosine-protein phosphatase DSP1
Authors:Wang, H, Shears, S.B.
Deposit date:2021-05-01
Release date:2022-03-02
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.
Nat Commun, 13, 2022
7MOM
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BU of 7mom by Molmil
Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) in complex with a metaphosphate intermediate
Descriptor: BETA-MERCAPTOETHANOL, PHOSPHITE ION, Tyrosine-protein phosphatase DSP1
Authors:Wang, H, Shears, S.B.
Deposit date:2021-05-01
Release date:2022-03-02
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.
Nat Commun, 13, 2022
7MOF
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BU of 7mof by Molmil
Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with 6-diphosphoinositol 1,2,3,4,5-pentakisphosphate 6-InsP7
Descriptor: (1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, INOSITOL HEXAKISPHOSPHATE, Tyrosine-protein phosphatase DSP1
Authors:Wang, H, Shears, S.B.
Deposit date:2021-05-01
Release date:2022-03-02
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.
Nat Commun, 13, 2022

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數據於2024-11-13公開中

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