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PDB: 447 件

8WTE
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Crystal structure of TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK)
分子名称: Beta-2-microglobulin, KRAS-G12V nonamer peptide, MHC class I antigen (Fragment), ...
著者Zhang, M.Y, Luo, L.J, Xu, W, Guan, F.H, Wang, X.Y, Zhu, P, Zhang, J.H, Zhou, X.Y, Wang, F, Ye, S.
登録日2023-10-18
公開日2024-05-01
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Identification and affinity enhancement of T-cell receptor targeting a KRAS G12V cancer neoantigen.
Commun Biol, 7, 2024
4IFT
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BU of 4ift by Molmil
Crystal structure of double mutant thermostable NPPase from Geobacillus stearothermophilus
分子名称: Thermostable NPPase
著者Guo, Z, Huang, J, Wang, F, Qiu, R, Wang, Y, Ji, C.
登録日2012-12-15
公開日2013-12-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.995 Å)
主引用文献Crystal structure of thermostable NPPase from Geobacillus stearothermophilus
To be Published
4IG4
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Crystal structure of single mutant thermostable NPPase (N86S) from Geobacillus stearothermophilus
分子名称: Thermostable NPPase
著者Guo, Z, Wang, F, Huang, J, Qiu, R, Yang, Z, Wang, Y, Gong, W, Ji, C.
登録日2012-12-16
公開日2013-12-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Crystal structure of thermostable NPPase from Geobacillus stearothermophilus
To be Published
8TIB
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BU of 8tib by Molmil
Cryo-EM of tri-pilus from S. islandicus REY15A
分子名称: DUF973 family protein
著者Eastep, G.N, Liu, J, Rich-New, S.T, Egelman, E.H, Krupovic, M, Wang, F.
登録日2023-07-19
公開日2024-01-10
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Two distinct archaeal type IV pili structures formed by proteins with identical sequence.
Nat Commun, 15, 2024
8TIF
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BU of 8tif by Molmil
Cryo-EM of mono-pilus from S. islandicus REY15A
分子名称: DUF973 family protein
著者Eastep, G.N, Liu, J, Rich-New, S.T, Egelman, E.H, Krupovic, M, Wang, F.
登録日2023-07-19
公開日2024-01-10
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.89 Å)
主引用文献Two distinct archaeal type IV pili structures formed by proteins with identical sequence.
Nat Commun, 15, 2024
4QY0
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BU of 4qy0 by Molmil
Structure of H10 from human-infecting H10N8
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin
著者Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
登録日2014-07-23
公開日2015-01-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
4QY2
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Structure of H10 from human-infecting H10N8 virus in complex with human receptor analog
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid, hemagglutinin
著者Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
登録日2014-07-23
公開日2015-01-28
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.399 Å)
主引用文献Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
6K9N
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BU of 6k9n by Molmil
Rice_OTUB_like_catalytic domain
分子名称: Ubiquitin thioesterase
著者Lu, L.N, Liu, L, Wang, F.
登録日2019-06-17
公開日2020-06-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains
Nat Commun, 13, 2022
6KBE
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Structure of Deubiquitinase
分子名称: Polyubiquitin-C, Ubiquitin thioesterase
著者Lu, L.N, Liu, L, Wang, F.
登録日2019-06-24
公開日2020-06-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.339 Å)
主引用文献Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains
Nat Commun, 13, 2022
6K9P
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Structure of Deubiquitinase
分子名称: Ubiquitin, Ubiquitin thioesterase
著者Lu, L.N, Liu, L, Wang, F.
登録日2019-06-17
公開日2020-06-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.047 Å)
主引用文献Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains
Nat Commun, 13, 2022
1T3P
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BU of 1t3p by Molmil
Half-sandwich arene ruthenium(II)-enzyme complex
分子名称: ACETATE ION, CHLORIDE ION, Lysozyme C, ...
著者McNae, I.W, Fishburne, K, Habtemariam, A, Hunter, T.M, Melchart, M, Wang, F, Walkinshaw, M.D, Sadler, P.J.
登録日2004-04-27
公開日2005-07-26
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Half-sandwich arene ruthenium(II)-enzyme complex
CHEM.COMMUN.(CAMB.), 16, 2004
6U8O
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Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
分子名称: 5-bromo-N-[5-(1-cyanocyclobutyl)-2-hydroxyphenyl]-2-hydroxybenzene-1-sulfonamide, WD repeat-containing protein 5
著者Zhao, B, Wang, F.
登録日2019-09-05
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019
6U8L
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Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
分子名称: 3-{[(5-bromo-2-hydroxyphenyl)sulfonyl]amino}-5-cyclopropyl-6-fluoro-2-hydroxybenzoic acid, N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]isoquinolin-1-amine, WD repeat-containing protein 5
著者Zhao, B, Wang, F.
登録日2019-09-05
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019
4KN8
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BU of 4kn8 by Molmil
Crystal structure of Bs-TpNPPase
分子名称: Thermostable NPPase
著者Guo, Z, Wang, F, Huang, J, Gong, W, Ji, C.
登録日2013-05-09
公開日2014-04-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.502 Å)
主引用文献Crystal Structure of Thermostable p-nitrophenylphosphatase from Bacillus Stearothermophilus (Bs-TpNPPase)
PROTEIN PEPT.LETT., 21, 2014
6IIL
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BU of 6iil by Molmil
USP14 catalytic domain bind to IU1-47
分子名称: 1-[1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(piperidin-1-yl)ethan-1-one, Ubiquitin carboxyl-terminal hydrolase 14
著者Mei, Z.Q, Wang, Y.W, Wang, F, Wang, J.W, He, W, Ding, S, Li, J.W.
登録日2018-10-07
公開日2018-12-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade.
Cell Res., 28, 2018
6IIM
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BU of 6iim by Molmil
USP14 catalytic domain with IU1-206
分子名称: 1-[1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(4-hydroxypiperidin-1-yl)ethan-1-one, Ubiquitin carboxyl-terminal hydrolase 14
著者Mei, Z.Q, Wang, J.W, Wang, F, Wang, Y.W.
登録日2018-10-07
公開日2018-12-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade.
Cell Res., 28, 2018
6IIN
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BU of 6iin by Molmil
USP14 catalytic domain with IU1-248
分子名称: 4-{3-[(4-hydroxypiperidin-1-yl)acetyl]-2,5-dimethyl-1H-pyrrol-1-yl}benzonitrile, Ubiquitin carboxyl-terminal hydrolase 14
著者Mei, Z.Q, Wang, J.W, Wang, F, Wang, Y.W.
登録日2018-10-07
公開日2018-12-19
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade.
Cell Res., 28, 2018
5EPO
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BU of 5epo by Molmil
The three-dimensional structure of Clostridium absonum 7alpha-hydroxysteroid dehydrogenase
分子名称: 7-alpha-hydroxysteroid deydrogenase, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Lou, D, Wang, B, Wang, F.
登録日2015-11-12
公開日2016-03-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The three-dimensional structure of Clostridium absonum 7 alpha-hydroxysteroid dehydrogenase: new insights into the conserved arginines for NADP(H) recognition
Sci Rep, 6, 2016
8FJS
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BU of 8fjs by Molmil
Structure of the Saccharolobus solfataricus archaeal type IV pilus at 3 Angstrom resolution
分子名称: Pilin_N domain-containing protein
著者Kreutzberger, M.A, Wang, F, Krupovic, M, Egelman, E.H.
登録日2022-12-20
公開日2023-06-28
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The evolution of archaeal flagellar filaments.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FK0
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Asymmetric cryo-EM structure of a curved Saccharolobus solfataricus type IV pilus
分子名称: Pilin_N domain-containing protein
著者Kreutzberger, M.A, Wang, F, Krupovic, M, Egelman, E.H.
登録日2022-12-20
公開日2023-06-28
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献The evolution of archaeal flagellar filaments.
Proc.Natl.Acad.Sci.USA, 120, 2023
7SLZ
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BU of 7slz by Molmil
CRYSTAL STRUCTURE OF GID4 IN COMPLEX WITH BPF023596
分子名称: Glucose-induced degradation protein 4 homolog, N-[(1s,4s)-4-(1H-benzimidazol-2-yl)cyclohexyl]-N~2~-[(1H-indol-2-yl)methyl]glycinamide
著者Song, X, Dong, A, Calabrese, M, Wang, F, Owen, D, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2021-10-25
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献CRYSTAL STRUCTURE OF GID4 IN COMPLEX WITH BPF023596
To Be Published
7SQD
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BU of 7sqd by Molmil
Cryo-EM structure of the Achromobacter flagellar filament
分子名称: Flagellin
著者Kreutzberger, M.A, Wang, F, Egelman, E.H.
登録日2021-11-05
公開日2022-03-16
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Flagellin outer domain dimerization modulates motility in pathogenic and soil bacteria from viscous environments.
Nat Commun, 13, 2022
7SN4
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Cryo-EM structure of the enterohemorrhagic E. coli O157:H7 flagellar filament
分子名称: Flagellin
著者Kreutzberger, M.A.B, Wang, F, Egelman, E.H.
登録日2021-10-27
公開日2022-03-16
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Flagellin outer domain dimerization modulates motility in pathogenic and soil bacteria from viscous environments.
Nat Commun, 13, 2022
8FXP
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Structure of capsid of Agrobacterium phage Milano
分子名称: Linking protein 1, gp16, Linking protein 2, ...
著者Sonani, R.R, Wang, F, Esteves, N.C, Kelly, R.J, Sebastian, A, Kreutzberger, M.A.B, Leiman, P.G, Scharf, B.E, Egelman, E.H.
登録日2023-01-25
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (4.04 Å)
主引用文献Neck and capsid architecture of the robust Agrobacterium phage Milano.
Commun Biol, 6, 2023
8FXR
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Structure of neck with portal vertex of capsid of Agrobacterium phage Milano
分子名称: Collar sheath protein, gp13, Linking protein 1, ...
著者Sonani, R.R, Wang, F, Esteves, N.C, Kelly, R.J, Sebastian, A, Kreutzberger, M.A.B, Leiman, P.G, Scharf, B.E, Egelman, E.H.
登録日2023-01-25
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Neck and capsid architecture of the robust Agrobacterium phage Milano.
Commun Biol, 6, 2023

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