8YHK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yhk by Molmil](/molmil-images/mine/8yhk) | The Crystal Structure of P21-Activated Kinases Pak4 from Biortus | Descriptor: | Serine/threonine-protein kinase PAK 4, TRIETHYLENE GLYCOL | Authors: | Wang, F, Cheng, W, Lv, Z, Qi, J, Wu, B. | Deposit date: | 2024-02-28 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The Crystal Structure of P21-Activated Kinases Pak4 from Biortus To Be Published
|
|
8ZGD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8zgd by Molmil](/molmil-images/mine/8zgd) | The Crystal Structure of the NLRP1_LRR domain from Biortus. | Descriptor: | GLYCEROL, NACHT, LRR and PYD domains-containing protein 1, ... | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Pan, W. | Deposit date: | 2024-05-09 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The Crystal Structure of the NLRP1_LRR domain from Biortus. To Be Published
|
|
8YGX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ygx by Molmil](/molmil-images/mine/8ygx) | |
8YHS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yhs by Molmil](/molmil-images/mine/8yhs) | The Crystal Structure of BRDT from Biortus. | Descriptor: | 1,2-ETHANEDIOL, 2,4-dimethyl-6-[6-(oxan-4-yl)-1-[(1~{S})-1-phenylethyl]imidazo[4,5-c]pyridin-2-yl]pyridazin-3-one, Bromodomain testis-specific protein | Authors: | Wang, F, Cheng, W, Lv, Z, Meng, Q, Lu, Y. | Deposit date: | 2024-02-28 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The Crystal Structure of BRDT from Biortus. To Be Published
|
|
4M83
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m83 by Molmil](/molmil-images/mine/4m83) | Ensemble refinement of protein crystal structure (2IYF) of macrolide glycosyltransferases OleD complexed with UDP and Erythromycin A | Descriptor: | ERYTHROMYCIN A, MAGNESIUM ION, Oleandomycin glycosyltransferase, ... | Authors: | Wang, F, Helmich, K.E, Xu, W, Singh, S, Olmos Jr, J.L, Martinez iii, E, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2013-08-12 | Release date: | 2013-09-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.698 Å) | Cite: | Crystal structure of macrolide glycosyltransferases OleD To be Published
|
|
4L7I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4l7i by Molmil](/molmil-images/mine/4l7i) | Crystal structure of S-Adenosylmethionine synthase from Sulfolobus solfataricus complexed with SAM and PPi | Descriptor: | DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Wang, F, Hurley, K.A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2013-06-13 | Release date: | 2013-07-03 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.189 Å) | Cite: | Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus. Febs J., 281, 2014
|
|
4M7P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m7p by Molmil](/molmil-images/mine/4m7p) | Ensemble refinement of protein crystal structure of macrolide glycosyltransferases OleD | Descriptor: | Oleandomycin glycosyltransferase, SODIUM ION | Authors: | Wang, F, Helmich, K.E, Xu, W, Singh, S, Olmos Jr, J.L, Martinez iii, E, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2013-08-12 | Release date: | 2013-09-11 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Crystal structure of macrolide glycosyltransferases OleD To be Published
|
|
2HVC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hvc by Molmil](/molmil-images/mine/2hvc) | The Crystal Structure of Ligand-binding Domain (LBD) of human Androgen Receptor in Complex with a selective modulator LGD2226 | Descriptor: | 6-[BIS(2,2,2-TRIFLUOROETHYL)AMINO]-4-(TRIFLUOROMETHYL)QUINOLIN-2(1H)-ONE, Androgen receptor | Authors: | Wang, F, Liu, X.-Q, Li, H, Liang, K.-N, Miner, J.N, Hong, M, Kallel, E.A, van Oeveren, A, Zhi, L, Jiang, T. | Deposit date: | 2006-07-28 | Release date: | 2007-07-31 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the ligand-binding domain (LBD) of human androgen receptor in complex with a selective modulator LGD2226 ACTA CRYSTALLOGR.,SECT.F, 62, 2006
|
|
2NTJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ntj by Molmil](/molmil-images/mine/2ntj) | Mycobacterium tuberculosis InhA bound with PTH-NAD adduct | Descriptor: | Enoyl-[acyl-carrier-protein] reductase [NADH, {(2R,3S,4R,5R)-5-[(4S)-3-(AMINOCARBONYL)-4-(2-PROPYLISONICOTINOYL)PYRIDIN-1(4H)-YL]-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL}M ETHYL [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE | Authors: | Wang, F, Sacchettini, J.C. | Deposit date: | 2006-11-07 | Release date: | 2007-01-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mechanism of thioamide drug action against tuberculosis and leprosy. J.Exp.Med., 204, 2007
|
|
8GZB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gzb by Molmil](/molmil-images/mine/8gzb) | SARS-CoV-2 3CLpro | Descriptor: | 1,2-ETHANEDIOL, 2-(4-chlorophenyl)-1,3,4-oxadiazole, 3C-like proteinase nsp5 | Authors: | Wang, F, Cen, Y.X, Tian, P. | Deposit date: | 2022-09-26 | Release date: | 2023-09-27 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Nature-inspired catalytic asymmetric rearrangement of cyclopropylcarbinyl cation. Sci Adv, 9, 2023
|
|
2NTV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ntv by Molmil](/molmil-images/mine/2ntv) | Mycobacterium leprae InhA bound with PTH-NAD adduct | Descriptor: | Enoyl-[ACP] reductase, {(2R,3S,4R,5R)-5-[(4S)-3-(AMINOCARBONYL)-4-(2-PROPYLISONICOTINOYL)PYRIDIN-1(4H)-YL]-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL}M ETHYL [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE | Authors: | Wang, F, Sacchettini, J.C. | Deposit date: | 2006-11-08 | Release date: | 2007-01-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mechanism of thioamide drug action against tuberculosis and leprosy. J.Exp.Med., 204, 2007
|
|
2K86
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2k86 by Molmil](/molmil-images/mine/2k86) | Solution Structure of FOXO3a Forkhead domain | Descriptor: | Forkhead box protein O3 | Authors: | Wang, F, Marshall, C.B, Li, G, Plevin, M.J, Ikura, M. | Deposit date: | 2008-09-02 | Release date: | 2008-10-14 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Biochemical and structural characterization of an intramolecular interaction in FOXO3a and its binding with p53. J.Mol.Biol., 384, 2008
|
|
5WJY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wjy by Molmil](/molmil-images/mine/5wjy) | |
5WJU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wju by Molmil](/molmil-images/mine/5wju) | Cryo-EM structure of B. subtilis flagellar filaments A39V, N133H | Descriptor: | Flagellin | Authors: | Wang, F, Burrage, A.M, Kearns, D.B, Egelman, E.H. | Deposit date: | 2017-07-24 | Release date: | 2017-10-25 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | A structural model of flagellar filament switching across multiple bacterial species. Nat Commun, 8, 2017
|
|
5WK6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wk6 by Molmil](/molmil-images/mine/5wk6) | |
5WJT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wjt by Molmil](/molmil-images/mine/5wjt) | |
7WKU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wku by Molmil](/molmil-images/mine/7wku) | Structure of PDCoV Mpro in complex with an inhibitor | Descriptor: | N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE, Peptidase C30 | Authors: | Wang, F.H, Yang, H.T. | Deposit date: | 2022-01-11 | Release date: | 2022-05-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Structure of the Porcine Deltacoronavirus Main Protease Reveals a Conserved Target for the Design of Antivirals. Viruses, 14, 2022
|
|
5WK5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wk5 by Molmil](/molmil-images/mine/5wk5) | |
5WJX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wjx by Molmil](/molmil-images/mine/5wjx) | Cryo-EM structure of B. subtilis flagellar filaments S17P | Descriptor: | Flagellin | Authors: | Wang, F, Burrage, A.M, Orlova, A, Kearns, D.B, Egelman, E.H. | Deposit date: | 2017-07-24 | Release date: | 2017-10-25 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (6.7 Å) | Cite: | A structural model of flagellar filament switching across multiple bacterial species. Nat Commun, 8, 2017
|
|
5WJW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wjw by Molmil](/molmil-images/mine/5wjw) | Cryo-EM structure of B. subtilis flagellar filaments H84R | Descriptor: | Flagellin | Authors: | Wang, F, Burrage, A.M, Orlova, A, Kearns, D.B, Egelman, E.H. | Deposit date: | 2017-07-24 | Release date: | 2017-10-25 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | A structural model of flagellar filament switching across multiple bacterial species. Nat Commun, 8, 2017
|
|
8J67
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j67 by Molmil](/molmil-images/mine/8j67) | Crystal structure of Toxoplasma gondii M2AP | Descriptor: | MIC2-associated protein | Authors: | Wang, F.F, Zhang, D.J, Zhang, S, Springer, T.A, Song, G.J. | Deposit date: | 2023-04-24 | Release date: | 2023-08-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Structural insights into MIC2 recognition by MIC2-associated protein in Toxoplasma gondii. Commun Biol, 6, 2023
|
|
5WJV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wjv by Molmil](/molmil-images/mine/5wjv) | |
5WJZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wjz by Molmil](/molmil-images/mine/5wjz) | Cryo-EM structure of B. subtilis flagellar filaments E115G | Descriptor: | Flagellin | Authors: | Wang, F, Burrage, A.M, Orlova, A, Kearns, D.B, Egelman, E.H. | Deposit date: | 2017-07-24 | Release date: | 2017-10-25 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (5.7 Å) | Cite: | A structural model of flagellar filament switching across multiple bacterial species. Nat Commun, 8, 2017
|
|
5VXX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vxx by Molmil](/molmil-images/mine/5vxx) | Cryo-EM reconstruction of Neisseria gonorrhoeae Type IV pilus | Descriptor: | Fimbrial protein, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, alpha-D-galactopyranose-(1-3)-2,4-bisacetamido-2,4,6-trideoxy-beta-D-glucopyranose | Authors: | Wang, F, Orlova, A, Altindal, T, Craig, L, Egelman, E.H. | Deposit date: | 2017-05-24 | Release date: | 2017-07-12 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Cryoelectron Microscopy Reconstructions of the Pseudomonas aeruginosa and Neisseria gonorrhoeae Type IV Pili at Sub-nanometer Resolution. Structure, 25, 2017
|
|
2GDN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gdn by Molmil](/molmil-images/mine/2gdn) | |