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PDB: 471 件

8EWG
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Cryo-EM structure of a riboendonclease
分子名称: CRISPR-associated endonuclease Cas9, RNA (56-MER)
著者Li, Z, Wang, F.
登録日2022-10-23
公開日2023-08-30
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural Basis for the Ribonuclease Activity of a Thermostable CRISPR-Cas13a from Thermoclostridium caenicola.
J.Mol.Biol., 435, 2023
3TLQ
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BU of 3tlq by Molmil
Crystal structure of EAL-like domain protein YdiV
分子名称: GLYCEROL, PHOSPHATE ION, Regulatory protein YdiV
著者Li, B, Li, N, Wang, F, Guo, L, Liu, C, Zhu, D, Xu, S, Gu, L.
登録日2011-08-30
公開日2012-09-12
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structural insight of a concentration-dependent mechanism by which YdiV inhibits Escherichia coli flagellum biogenesis and motility
Nucleic Acids Res., 40, 2012
1HM1
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THE SOLUTION NMR STRUCTURE OF A THERMALLY STABLE FAPY ADDUCT OF AFLATOXIN B1 IN AN OLIGODEOXYNUCLEOTIDE DUPLEX REFINED FROM DISTANCE RESTRAINED MOLECULAR DYNAMICS SIMULATED ANNEALING, MINIMIZED AVERAGE STRUCTURE
分子名称: DNA (5'-D(*CP*TP*AP*TP*(FAG)P*AP*TP*TP*CP*A)-3'), DNA (5'-D(TP*GP*AP*AP*TP*CP*AP*TP*AP*G)-3')
著者Mao, H, Deng, Z, Wang, F, Harris, T.M, Stone, M.P.
登録日1998-05-11
公開日1998-10-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献An intercalated and thermally stable FAPY adduct of aflatoxin B1 in a DNA duplex: structural refinement from 1H NMR.
Biochemistry, 37, 1998
3RLR
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BU of 3rlr by Molmil
Co-crystal structure of the HSP90 ATP binding domain in complex with 4-(2,4-dichloro-5-methoxyphenyl)-2,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
分子名称: 4-(2,4-dichloro-5-methoxyphenyl)-2,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Heat shock protein HSP 90-alpha, PHOSPHATE ION
著者Kung, P.-P, Sinnema, P.-J, Richardson, P, Hickey, M.J, Gajiwala, K.S, Wang, F, Huang, B, McClellan, G, Wang, J, Maegley, K, Bergqvist, S, Mehta, P.P, Kania, R.
登録日2011-04-20
公開日2011-06-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Design strategies to target crystallographic waters applied to the Hsp90 molecular chaperone.
Bioorg.Med.Chem.Lett., 21, 2011
4KN8
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BU of 4kn8 by Molmil
Crystal structure of Bs-TpNPPase
分子名称: Thermostable NPPase
著者Guo, Z, Wang, F, Huang, J, Gong, W, Ji, C.
登録日2013-05-09
公開日2014-04-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.502 Å)
主引用文献Crystal Structure of Thermostable p-nitrophenylphosphatase from Bacillus Stearothermophilus (Bs-TpNPPase)
PROTEIN PEPT.LETT., 21, 2014
8TIB
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BU of 8tib by Molmil
Cryo-EM of tri-pilus from S. islandicus REY15A
分子名称: DUF973 family protein
著者Eastep, G.N, Liu, J, Rich-New, S.T, Egelman, E.H, Krupovic, M, Wang, F.
登録日2023-07-19
公開日2024-01-10
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Two distinct archaeal type IV pili structures formed by proteins with identical sequence.
Nat Commun, 15, 2024
8TIF
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Cryo-EM of mono-pilus from S. islandicus REY15A
分子名称: DUF973 family protein
著者Eastep, G.N, Liu, J, Rich-New, S.T, Egelman, E.H, Krupovic, M, Wang, F.
登録日2023-07-19
公開日2024-01-10
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.89 Å)
主引用文献Two distinct archaeal type IV pili structures formed by proteins with identical sequence.
Nat Commun, 15, 2024
3J3T
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Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
分子名称: Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
著者Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N.
登録日2013-04-18
公開日2013-05-15
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3J3R
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Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
分子名称: Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
著者Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N.
登録日2013-04-18
公開日2013-05-15
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (9.4 Å)
主引用文献Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine
J.Biol.Chem., 288, 2013
4Y2I
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Gold ion bound to GolB
分子名称: GOLD ION, Putative metal-binding transport protein
著者Wei, W, Wang, F, Ma, L, Zhao, J.
登録日2015-02-10
公開日2016-02-10
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights and the Surprisingly Low Mechanical Stability of the Au-S Bond in the Gold-Specific Protein GolB
J.Am.Chem.Soc., 137, 2015
3JCP
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Structure of yeast 26S proteasome in M2 state derived from Titan dataset
分子名称: 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ...
著者Luan, B, Huang, X.L, Wu, J.P, Shi, Y.G, Wang, F.
登録日2016-01-06
公開日2016-06-15
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structure of an endogenous yeast 26S proteasome reveals two major conformational states.
Proc.Natl.Acad.Sci.USA, 113, 2016
4Y2K
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reduced form of apo-GolB
分子名称: Putative metal-binding transport protein
著者Wei, W, Wang, F, Ma, L, Zhao, J.
登録日2015-02-10
公開日2016-02-10
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Insights and the Surprisingly Low Mechanical Stability of the Au-S Bond in the Gold-Specific Protein GolB
J.Am.Chem.Soc., 137, 2015
3J3U
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BU of 3j3u by Molmil
Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
分子名称: Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
著者Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N.
登録日2013-04-18
公開日2013-05-15
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
4Y2M
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apo-GolB protein
分子名称: GOLD ION, Putative metal-binding transport protein
著者Wei, W, Zhao, J, Wang, F.
登録日2015-02-10
公開日2016-02-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural Insights and the Surprisingly Low Mechanical Stability of the Au-S Bond in the Gold-Specific Protein GolB
J.Am.Chem.Soc., 137, 2015
3J3S
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BU of 3j3s by Molmil
Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
分子名称: Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
著者Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N.
登録日2013-04-18
公開日2013-05-15
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (11 Å)
主引用文献Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3RLP
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BU of 3rlp by Molmil
Co-crystal structure of the HSP90 ATP binding domain in complex with 4-(2,4-dichloro-5-methoxyphenyl)-6-methylpyrimidin-2-amine
分子名称: 4-(2,4-dichloro-5-methoxyphenyl)-6-methylpyrimidin-2-amine, Heat shock protein HSP 90-alpha, PHOSPHATE ION
著者Kung, P.-P, Sinnema, P.-J, Richardson, P, Hickey, M.J, Gajiwala, K.S, Wang, F, Huang, B, McClellan, G, Wang, J, Maegley, K, Bergqvist, S, Mehta, P.P, Kania, R.
登録日2011-04-20
公開日2011-06-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Design strategies to target crystallographic waters applied to the Hsp90 molecular chaperone.
Bioorg.Med.Chem.Lett., 21, 2011
5VSR
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BU of 5vsr by Molmil
ABA-mimicking ligand AMF4 in complex with ABA receptor PYL2 and PP2C HAB1
分子名称: Abscisic acid receptor PYL2, MAGNESIUM ION, N-(2-oxo-1-propyl-1,2,3,4-tetrahydroquinolin-6-yl)-1-(2,3,5,6-tetrafluoro-4-methylphenyl)methanesulfonamide, ...
著者Cao, M.-J, Zhang, Y.-L, Liu, X, Huang, H, Zhou, X.E, Wang, W.-L, Zeng, A, Zhao, C.-Z, Si, T, Du, J.-M, Wu, W.-W, Wang, F.-X, Xu, H.X, Zhu, J.-K.
登録日2017-05-12
公開日2017-11-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.618 Å)
主引用文献Combining chemical and genetic approaches to increase drought resistance in plants.
Nat Commun, 8, 2017
5VRO
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BU of 5vro by Molmil
ABA-mimicking ligand AMF1beta in complex with ABA receptor PYL2 and PP2C HAB1
分子名称: 1-(3-fluoro-4-methylphenyl)-N-(2-oxo-1-propyl-1,2,3,4-tetrahydroquinolin-6-yl)methanesulfonamide, Abscisic acid receptor PYL2, MAGNESIUM ION, ...
著者Cao, M.-J, Zhang, Y.-L, Liu, X, Huang, H, Zhou, X.E, Wang, W.-L, Zeng, A, Zhao, C.-Z, Si, T, Du, J.-M, Wu, W.-W, Wang, F.-X, Xu, H.X, Zhu, J.-K.
登録日2017-05-11
公開日2017-11-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.257 Å)
主引用文献Combining chemical and genetic approaches to increase drought resistance in plants.
Nat Commun, 8, 2017
5VT7
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BU of 5vt7 by Molmil
ABA-mimicking ligand AMC1beta in complex with ABA receptor PYL2 and PP2C HAB1
分子名称: 1-(3-chloro-4-methylphenyl)-N-(2-oxo-1-propyl-1,2,3,4-tetrahydroquinolin-6-yl)methanesulfonamide, Abscisic acid receptor PYL2, MAGNESIUM ION, ...
著者Cao, M.-J, Zhang, Y.-L, Liu, X, Huang, H, Zhou, X.E, Wang, W.-L, Zeng, A, Zhao, C.-Z, Si, T, Du, J.-M, Wu, W.-W, Wang, F.-X, Xu, H.X, Zhu, J.-K.
登録日2017-05-15
公開日2017-11-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.624 Å)
主引用文献Combining chemical and genetic approaches to increase drought resistance in plants.
Nat Commun, 8, 2017
6U80
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Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
分子名称: 5-bromo-N-(4-hydroxy[1,1'-biphenyl]-3-yl)-2-methoxybenzene-1-sulfonamide, WD repeat-containing protein 5
著者Zhao, B, Wang, F.
登録日2019-09-04
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019
6U7M
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BU of 6u7m by Molmil
Cryo-EM Structure of Helical Lipoprotein Lipase
分子名称: Lipoprotein lipase
著者Gunn, K.H, Wang, F, Egelman, E.H, Neher, S.B.
登録日2019-09-03
公開日2020-04-08
最終更新日2020-05-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage.
Proc.Natl.Acad.Sci.USA, 117, 2020
5X7U
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Trehalose synthase from Thermobaculum terrenum
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, Trehalose synthase
著者Su, J, Wang, F.
登録日2017-02-27
公開日2018-02-28
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Structural Characteristics and Function of a New Kind of Thermostable Trehalose Synthase from Thermobaculum terrenum.
J. Agric. Food Chem., 65, 2017
6U5Y
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Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
分子名称: 3-{[(5-bromo-3-chloro-2-hydroxyphenyl)sulfonyl]amino}-5-(1-cyanocyclobutyl)-2-hydroxy-N-methylbenzamide, WD repeat-containing protein 5
著者Zhao, B, Wang, F.
登録日2019-08-28
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.532 Å)
主引用文献Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019
6U5M
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Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
分子名称: 5-bromo-2-hydroxy-N-[3-(methylsulfonyl)-5-(pentafluoro-lambda~6~-sulfanyl)phenyl]benzene-1-sulfonamide, WD repeat-containing protein 5
著者Zhao, B, Wang, F.
登録日2019-08-28
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019
6U8O
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BU of 6u8o by Molmil
Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
分子名称: 5-bromo-N-[5-(1-cyanocyclobutyl)-2-hydroxyphenyl]-2-hydroxybenzene-1-sulfonamide, WD repeat-containing protein 5
著者Zhao, B, Wang, F.
登録日2019-09-05
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019

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件を2024-08-21に公開中

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