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PDB: 462 件
4WIL
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BU of 4wil by Molmil
Crystal structure of DCoH2 S51T
分子名称: Pterin-4-alpha-carbinolamine dehydratase 2
著者Wang, D, Rose, R.B.
登録日2014-09-26
公開日2014-12-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Interactions with the Bifunctional Interface of the Transcriptional Coactivator DCoH1 Are Kinetically Regulated.
J.Biol.Chem., 290, 2015
3M4O
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BU of 3m4o by Molmil
RNA polymerase II elongation complex B
分子名称: DNA (28-MER), DNA (5'-D(P*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
著者Wang, D, Zhu, G, Huang, X, Lippard, S.J.
登録日2010-03-11
公開日2010-05-12
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.57 Å)
主引用文献X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M3Y
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BU of 3m3y by Molmil
RNA polymerase II elongation complex C
分子名称: DNA (28-MER), DNA (5'-D(*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
著者Wang, D, Zhu, G, Huang, X, Lippard, S.J.
登録日2010-03-10
公開日2010-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct.
Proc.Natl.Acad.Sci.USA, 107, 2010
1S9K
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BU of 1s9k by Molmil
Crystal Structure of Human NFAT1 and Fos-Jun on the IL-2 ARRE1 Site
分子名称: Human IL-2 ARRE1 Promoter Element, Minus Strand, Plus Strand, ...
著者Wang, D, Stroud, J.C, Chen, L.
登録日2004-02-04
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of Human NFAT1 and Fos-Jun on the IL-2 ARRE1 Site
To be Published
6A8G
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BU of 6a8g by Molmil
The crystal structure of muPAin-1-IG in complex with muPA-SPD at pH8.5
分子名称: PHOSPHATE ION, Urokinase-type plasminogen activator chain B, muPAin-1-IG
著者Wang, D, Yang, Y.S, Jiang, L.G, Huang, M.D, Li, J.Y, Andreasen, P.A, Xu, P, Chen, Z.
登録日2018-07-08
公開日2019-02-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides.
J.Med.Chem., 62, 2019
6A8N
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BU of 6a8n by Molmil
The crystal structure of muPAin-1-IG-2 in complex with muPA-SPD at pH8.5
分子名称: CYS-PRO-ALA-TYR-SER-ARG-TYR-ILE-GLY-CYS, Urokinase-type plasminogen activator B
著者Wang, D, Yang, Y.S, Jiang, L.G, Huang, M.D, Li, J.Y, Andreasen, P.A, Xu, P, Chen, Z.
登録日2018-07-09
公開日2019-02-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.489 Å)
主引用文献Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides.
J.Med.Chem., 62, 2019
2YU9
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BU of 2yu9 by Molmil
RNA polymerase II elongation complex in 150 mm MG+2 with UTP
分子名称: 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ...
著者Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
登録日2007-04-06
公開日2007-04-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
Cell(Cambridge,Mass.), 127, 2006
4FF5
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BU of 4ff5 by Molmil
Structure basis of a novel virulence factor GHIP a glycosyl hydrolase 25 of Streptococcus pneumoniae participating in host cell invasion
分子名称: 1,2-ETHANEDIOL, Glycosyl hydrolase 25
著者Wang, D.
登録日2012-05-31
公開日2013-07-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural basis of the novel S. pneumoniae virulence factor, GHIP, a glycosyl hydrolase 25 participating in host-cell invasion.
Plos One, 8, 2013
3OSV
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BU of 3osv by Molmil
The crytsal structure of FLGD from P. Aeruginosa
分子名称: Flagellar basal-body rod modification protein FlgD, GLYCEROL
著者Wang, D, Luo, M, Niu, S.
登録日2010-09-10
公開日2011-05-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structure of a novel dimer form of FlgD from P. aeruginosa PAO1
Proteins, 79, 2011
8YYR
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BU of 8yyr by Molmil
Structure of the HitB T293G mutant
分子名称: Putative ATP-dependent b-aminoacyl-ACP synthetase, [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[(3~{S})-3-azanyl-3-(2-bromophenyl)propanoyl]sulfamate
著者Wang, D, Miyanaga, A, Chisuga, T, Kudo, F, Eguchi, T.
登録日2024-04-04
公開日2024-06-05
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Engineering the Substrate Specificity of (S)-beta-Phenylalanine Adenylation Enzyme HitB.
Chembiochem, 25, 2024
8YYQ
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BU of 8yyq by Molmil
Structure of the HitB F328L mutant
分子名称: Putative ATP-dependent b-aminoacyl-ACP synthetase, [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[(3~{S})-3-azanyl-3-(3-cyanophenyl)propanoyl]sulfamate
著者Wang, D, Miyanaga, A, Chisuga, T, Kudo, F, Eguchi, T.
登録日2024-04-04
公開日2024-06-05
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Engineering the Substrate Specificity of (S)-beta-Phenylalanine Adenylation Enzyme HitB.
Chembiochem, 25, 2024
2E2J
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BU of 2e2j by Molmil
RNA polymerase II elongation complex in 5 mM Mg+2 with GMPCPP
分子名称: 27-MER DNA template strand, 5'-D(P*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*A)-3', 5'-R(P*AP*UP*CP*GP*AP*GP*AP*GP*G)-3', ...
著者Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
登録日2006-11-14
公開日2006-12-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2E2H
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BU of 2e2h by Molmil
RNA polymerase II elongation complex at 5 mM Mg2+ with GTP
分子名称: 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ...
著者Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
登録日2006-11-14
公開日2006-12-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2E2I
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BU of 2e2i by Molmil
RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dGTP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', ...
著者Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
登録日2006-11-14
公開日2006-12-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.41 Å)
主引用文献Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2CGA
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BU of 2cga by Molmil
BOVINE CHYMOTRYPSINOGEN A. X-RAY CRYSTAL STRUCTURE ANALYSIS AND REFINEMENT OF A NEW CRYSTAL FORM AT 1.8 ANGSTROMS RESOLUTION
分子名称: CHYMOTRYPSINOGEN A
著者Wang, D, Bode, W, Huber, R.
登録日1987-01-16
公開日1987-04-16
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Bovine chymotrypsinogen A X-ray crystal structure analysis and refinement of a new crystal form at 1.8 A resolution.
J.Mol.Biol., 185, 1985
5IFF
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BU of 5iff by Molmil
Crystal structure of R.PabI-nonspecific DNA complex
分子名称: DNA (5'-D(*GP*CP*AP*CP*TP*AP*GP*TP*TP*CP*GP*AP*AP*CP*TP*AP*GP*TP*GP*C)-3'), Uncharacterized protein
著者Wang, D, Miyazono, K, Tanokura, M.
登録日2016-02-26
公開日2016-11-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Tetrameric structure of the restriction DNA glycosylase R.PabI in complex with nonspecific double-stranded DNA.
Sci Rep, 6, 2016
5X8Y
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BU of 5x8y by Molmil
A Mutation identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in vitro
分子名称: ZIKV NS1
著者Wang, D, Chen, C, Liu, S, Zhou, H, Yang, K, Zhao, Q, Ji, X, Chen, C, Xie, W, Wang, Z, Mi, L.Z, Yang, H.
登録日2017-03-03
公開日2017-05-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.817 Å)
主引用文献A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in Vitro
Sci Rep, 7, 2017
5CRL
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BU of 5crl by Molmil
Crystal Structure of the Transcription Activator Tn501 MerR in Complex with Mercury (II)
分子名称: MERCURY (II) ION, Mercuric resistance operon regulatory protein
著者Wang, D, Gan, J.H, Chen, H.
登録日2015-07-23
公開日2016-09-07
最終更新日2023-04-12
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Analysis of the Hg(II)-Regulatory Protein Tn501 MerR from Pseudomonas aeruginosa.
Sci Rep, 6, 2016
3GTK
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BU of 3gtk by Molmil
Backtracked RNA polymerase II complex with 18mer RNA
分子名称: DNA (29-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
著者Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
登録日2009-03-27
公開日2009-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTP
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BU of 3gtp by Molmil
Backtracked RNA polymerase II complex with 24mer RNA
分子名称: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
著者Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
登録日2009-03-27
公開日2009-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTL
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BU of 3gtl by Molmil
Backtracked RNA polymerase II complex with 13mer with G<>U mismatch
分子名称: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
著者Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
登録日2009-03-27
公開日2009-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.38 Å)
主引用文献Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTQ
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BU of 3gtq by Molmil
Backtracked RNA polymerase II complex induced by damage
分子名称: DNA (5'-D(*CP*TP*AP*CP*CP*CP*AP*TP*AP*AP*CP*CP*AP*CP*AP*GP*GP*CP*TP*CP*CP*TP*CP*TP*CP*CP*AP*TP*C)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
著者Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
登録日2009-03-27
公開日2009-06-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTO
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BU of 3gto by Molmil
Backtracked RNA polymerase II complex with 15mer RNA
分子名称: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
著者Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
登録日2009-03-27
公開日2009-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTG
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BU of 3gtg by Molmil
Backtracked RNA polymerase II complex with 12mer RNA
分子名称: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
著者Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
登録日2009-03-27
公開日2009-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.78 Å)
主引用文献Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTM
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BU of 3gtm by Molmil
Co-complex of Backtracked RNA polymerase II with TFIIS
分子名称: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
著者Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
登録日2009-03-27
公開日2009-06-09
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009

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