8YYR

Structure of the HitB T293G mutant

This is a non-PDB format compatible entry.

Summary for 8YYR

• Entry DOI: 10.2210/pdb8yyr/pdb
• Descriptor: Putative ATP-dependent b-aminoacyl-ACP synthetase, [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[(3~{S})-3-azanyl-3-(2-bromophenyl)propanoyl]sulfamate (3 entities in total)
• Functional Keywords: hitachimycin, polyketide biosynthesis, atp binding, adenylation, ligase
• Biological source: Embleya scabrispora
• Total number of polymer chains: 1
• Total formula weight: 60203.04

Authors

Wang, D.,Miyanaga, A.,Chisuga, T.,Kudo, F.,Eguchi, T. (deposition date: 2024-04-04, release date: 2024-06-05)

• Primary citation: Wang, D.,Miyanaga, A.,Chisuga, T.,Kudo, F.,Eguchi, T.; Engineering the Substrate Specificity of (S)-beta-Phenylalanine Adenylation Enzyme HitB.; Chembiochem, :e202400383-e202400383, 2024; PubMed: 38805007; DOI: 10.1002/cbic.202400383

Experimental method

X-RAY DIFFRACTION (1.8 Å)