5HDK
 
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3FHW
 | | Crystal structure of the protein priB from Bordetella parapertussis. Northeast Structural Genomics Consortium target BpR162. | | Descriptor: | DI(HYDROXYETHYL)ETHER, Primosomal replication protein n, SODIUM ION | | Authors: | Kuzin, A.P, Neely, H, Seetharaman, J, Forouhar, F, Wang, D, Mao, L, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-12-10 | | Release date: | 2008-12-30 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of the protein priB from Bordetella parapertussis. Northeast Structural Genomics Consortium target BpR162.
To be Published
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5C65
 | | Structure of the human glucose transporter GLUT3 / SLC2A3 | | Descriptor: | CHOLESTEROL HEMISUCCINATE, Octyl Glucose Neopentyl Glycol, Solute carrier family 2, ... | | Authors: | Pike, A.C.W, Quigley, A, Chu, A, Tessitore, A, Xia, X, Mukhopadhyay, S, Wang, D, Kupinska, K, Strain-Damerell, C, Chalk, R, Burgess-Brown, N.A, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | | Deposit date: | 2015-06-22 | | Release date: | 2015-07-08 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structure of the human glucose transporter GLUT3 / SLC2A3
To Be Published
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5HSO
 | | Crystal structure of MYCOBACTERIUM TUBERCULOSIS MARR FAMILY PROTEIN Rv2887 complex with DNA | | Descriptor: | DNA (30-MER), the upstream sequence of Rv0560c, Uncharacterized HTH-type transcriptional regulator Rv2887 | | Authors: | Gao, Y.R, Li, D.F, Wang, D.C, Bi, L.J. | | Deposit date: | 2016-01-26 | | Release date: | 2017-02-01 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural analysis of the regulatory mechanism of MarR protein Rv2887 in M. tuberculosis
Sci Rep, 7, 2017
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5DAJ
 | | Crystal structure of NalD, the secondary repressor of MexAB-OprM multidrug efflux pump in Pseudomonas aeruginosa | | Descriptor: | NalD | | Authors: | Chen, W.Z, Wang, D, Huang, S.Q, Hu, Q.Y, Liu, X.C, Gan, J.H, Chen, H. | | Deposit date: | 2015-08-20 | | Release date: | 2016-04-20 | | Last modified: | 2023-04-12 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Novobiocin binding to NalD induces the expression of the MexAB-OprM pump in Pseudomonas aeruginosa
Mol.Microbiol., 100, 2016
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3HC3
 | | BHA10 IgG1 Fab double mutant variant - antibody directed at human LTBR | | Descriptor: | ACETATE ION, IMMUNOGLOBULIN IGG1 FAB, HEAVY CHAIN, ... | | Authors: | Arndt, J.W, Jordan, J.L, Lugovskoy, A, Wang, D. | | Deposit date: | 2009-05-05 | | Release date: | 2009-08-04 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Structural understanding of stabilization patterns in engineered bispecific Ig-like antibody molecules
Proteins, 77, 2009
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3HC4
 | | BHA10 IgG1 Fab quadruple mutant variant - antibody directed at human LTBR | | Descriptor: | ACETATE ION, IMMUNOGLOBULIN IGG1 FAB, HEAVY CHAIN, ... | | Authors: | Arndt, J.W, Jordan, J.L, Lugovskoy, A, Wang, D. | | Deposit date: | 2009-05-05 | | Release date: | 2009-08-04 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Structural understanding of stabilization patterns in engineered bispecific Ig-like antibody molecules
Proteins, 77, 2009
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3SP4
 | | Crystal structure of aprataxin ortholog Hnt3 from Schizosaccharomyces pombe | | Descriptor: | Aprataxin-like protein, SULFATE ION, ZINC ION | | Authors: | Gong, Y, Zhu, D, Ding, J, Dou, C, Ren, X, Jiang, T, Wang, D. | | Deposit date: | 2011-07-01 | | Release date: | 2011-10-12 | | Last modified: | 2013-07-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA
Nat.Struct.Mol.Biol., 18, 2011
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3GWW
 | | Leucine transporter LeuT in complex with S-fluoxetine | | Descriptor: | (3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, LEUCINE, SODIUM ION, ... | | Authors: | Zhou, Z, Zhen, J, Karpowich, N.K, Law, C.J, Reith, M.E.A, Wang, D.N. | | Deposit date: | 2009-04-01 | | Release date: | 2009-05-12 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.46 Å) | | Cite: | Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures.
Nat.Struct.Mol.Biol., 16, 2009
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3TC1
 | | Crystal Structure of Octaprenyl Pyrophosphate Synthase from Helicobacter pylori | | Descriptor: | MAGNESIUM ION, Octaprenyl Pyrophosphate Synthase | | Authors: | Zhang, J.Y, Zhang, X.L, Li, D.F, Zou, Q.M, Wang, D.C. | | Deposit date: | 2011-08-08 | | Release date: | 2011-08-31 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of Octaprenyl Pyrophosphate Synthase from Helicobacter pylori
To be Published
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6JBI
 | | Structure of Tps1 apo structure | | Descriptor: | Trehalose-6-phosphate synthase | | Authors: | Wang, S, Zhao, Y, Yi, L, Wang, D, Liu, J. | | Deposit date: | 2019-01-25 | | Release date: | 2019-12-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1.
Biochem.J., 476, 2019
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3C96
 | | Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa. Northeast Structural Genomics Consortium target PaR240 | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Flavin-containing monooxygenase | | Authors: | Vorobiev, S.M, Chen, Y, Seetharaman, J, Wang, D, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-02-15 | | Release date: | 2008-02-26 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa.
To be Published
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7A6U
 | | Cryo-EM structure of the cytoplasmic domain of human TRPC6 | | Descriptor: | Short transient receptor potential channel 6, UNKNOWN ATOM OR ION | | Authors: | Grieben, M, Pike, A.C.W, Wang, D, Mukhopadhyay, S.M.M, Chalk, R, Marsden, B.D, Burgess-Brown, N.A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | | Deposit date: | 2020-08-26 | | Release date: | 2020-09-30 | | Last modified: | 2021-07-07 | | Method: | ELECTRON MICROSCOPY (3.62 Å) | | Cite: | Cryo-EM structure of the cytoplasmic domain of human TRPC6
TO BE PUBLISHED
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2P3Y
 | | Crystal structure of VPA0735 from Vibrio parahaemolyticus. NorthEast Structural Genomics target VpR109 | | Descriptor: | Hypothetical protein VPA0735 | | Authors: | Seetharaman, J, Neely, H, Forouhar, F, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xia, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2007-03-10 | | Release date: | 2007-03-27 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of VPA0735 from Vibrio parahaemolyticus.
To be Published
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3DA1
 | | X-Ray structure of the glycerol-3-phosphate dehydrogenase from Bacillus halodurans complexed with FAD. Northeast Structural Genomics Consortium target BhR167. | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Glycerol-3-phosphate dehydrogenase | | Authors: | Kuzin, A.P, Abashidze, M, Seetharaman, J, Wang, D, Janjua, H, Owens, L, Xiao, R, Nair, R, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-05-28 | | Release date: | 2008-07-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | X-Ray structure of the glycerol-3-phosphate dehydrogenase from Bacillus halodurans complexed with FAD. Northeast Structural Genomics Consortium target BhR167.
To be Published
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3DME
 | | Crystal structure of conserved exported protein from Bordetella pertussis. NorthEast Structural Genomics target BeR141 | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, L(+)-TARTARIC ACID, conserved exported protein | | Authors: | Seetharaman, J, Abashidze, M, Wang, D, Janjua, H, Foote, E.L, Xiao, R, Liu, J, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-06-30 | | Release date: | 2008-08-26 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of conserved exported protein from Bordetella pertussis. NorthEast Structural Genomics target BeR141
To be Published
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2PIH
 | | Crystal structure of Protein ymcA from Bacillus subtilis, NorthEast Structural Genomics target SR375 | | Descriptor: | Protein ymcA | | Authors: | Seetharaman, J, Abashidze, M, Forouhar, F, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xia, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2007-04-13 | | Release date: | 2007-05-01 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of Protein ymcA from Bacillus subtilis.
To be Published
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3K2T
 | | Crystal structure of Lmo2511 protein from Listeria monocytogenes, northeast structural genomics consortium target LkR84A | | Descriptor: | Lmo2511 protein | | Authors: | Seetharaman, J, Su, M, Wang, D, Janjua, H, Cunningham, K, Owens, L, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-09-30 | | Release date: | 2009-11-03 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of Lmo2511 protein from Listeria monocytogenes, northeast structural genomics consortium target LkR84A
To be Published
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2Q00
 | | Crystal structure of the P95883_SULSO protein from Sulfolobus solfataricus. NESG target SsR10. | | Descriptor: | Orf c02003 protein | | Authors: | Vorobiev, S.M, Chen, Y, Seetharaman, J, Wang, D, Owens, L, Ma, L.-C, Cunningham, K, Fang, Y, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2007-05-18 | | Release date: | 2007-05-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the P95883_SULSO protein from Sulfolobus solfataricus.
To be Published
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5T0U
 | | CTCF ZnF2-7 and DNA complex structure | | Descriptor: | DNA (5'-D(*CP*CP*TP*CP*AP*CP*TP*AP*GP*CP*GP*CP*CP*CP*CP*CP*TP*GP*CP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*GP*GP*CP*GP*CP*TP*AP*GP*TP*GP*AP*GP*G)-3'), Transcriptional repressor CTCF, ... | | Authors: | Hashimoto, H, Wang, D, Cheng, X. | | Deposit date: | 2016-08-16 | | Release date: | 2017-05-24 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3.199 Å) | | Cite: | Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Mol. Cell, 66, 2017
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3VNC
 | | Crystal Structure of TIP-alpha N25 from Helicobacter Pylori in its natural dimeric form | | Descriptor: | TIP-alpha | | Authors: | Gao, M, Li, D, Hu, Y, Zou, Q, Wang, D.-C. | | Deposit date: | 2012-01-11 | | Release date: | 2012-10-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structure of TNF-alpha-Inducing Protein from Helicobacter Pylori in Active Form Reveals the Intrinsic Molecular Flexibility for Unique DNA-Binding
Plos One, 7, 2012
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3ELI
 | | Crystal structure of the AHSA1 (SPO3351) protein from Silicibacter pomeroyi, Northeast Structural Genomics Consortium Target SiR160 | | Descriptor: | Aha1 domain protein | | Authors: | Forouhar, F, Su, M, Seetharaman, J, Janjua, H, Xiao, R, Ciccosanti, C, Foote, E.L, Wang, D, Tong, S, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-09-22 | | Release date: | 2008-09-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of the AHSA1 (SPO3351) protein from Silicibacter pomeroyi, Northeast Structural Genomics Consortium Target SiR160
To be Published
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3PU2
 | | Crystal Structure of the Q3J4M4_RHOS4 protein from Rhodobacter sphaeroides. Northeast Structural Genomics Consortium Target RhR263. | | Descriptor: | uncharacterized protein | | Authors: | Vorobiev, S, Chen, Y, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-12-03 | | Release date: | 2010-12-15 | | Last modified: | 2012-02-22 | | Method: | X-RAY DIFFRACTION (2.606 Å) | | Cite: | Crystal Structure of the Q3J4M4_RHOS4 protein from Rhodobacter sphaeroides.
To be Published
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3KW6
 | | Crystal Structure of a domain of 26S proteasome regulatory subunit 8 from homo sapiens. Northeast Structural Genomics Consortium target id HR3102A | | Descriptor: | 26S protease regulatory subunit 8 | | Authors: | Seetharaman, J, Su, M, Wang, D, Janjua, H, Cunningham, K, Owens, L, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-11-30 | | Release date: | 2009-12-22 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structure of a domain of 26S proteasome regulatory subunit 8 from homo sapiens. Northeast Structural Genomics Consortium target id HR3102A
To be Published
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5HDN
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