3A7H
| Human MST3 kinase in complex with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Serine/threonine kinase 24 (STE20 homolog, yeast) | Authors: | Ko, T.P, Jeng, W.Y, Liu, C.I, Lai, M.D, Wang, A.H.J. | Deposit date: | 2009-09-26 | Release date: | 2010-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structures of human MST3 kinase in complex with adenine, ADP and Mn2+. Acta Crystallogr.,Sect.D, 66, 2010
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1JP3
| Structure of E.coli undecaprenyl pyrophosphate synthase | Descriptor: | 2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, undecaprenyl pyrophosphate synthase | Authors: | Ko, T.P, Chen, Y.K, Robinson, H, Tsai, P.C, Gao, Y.G, Chen, A.P.C, Wang, A.H.J, Liang, P.H. | Deposit date: | 2001-07-31 | Release date: | 2001-08-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mechanism of product chain length determination and the role of a flexible loop in Escherichia coli undecaprenyl-pyrophosphate synthase catalysis. J.Biol.Chem., 276, 2001
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1KUK
| Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with pEKW. | Descriptor: | CADMIUM ION, EKW, metalloproteinase | Authors: | Huang, K.F, Chiou, S.H, Ko, T.P, Wang, A.H.J. | Deposit date: | 2002-01-22 | Release date: | 2002-07-10 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues. Eur.J.Biochem., 269, 2002
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1KUF
| High-resolution Crystal Structure of a Snake Venom Metalloproteinase from Taiwan Habu | Descriptor: | CADMIUM ION, metalloproteinase | Authors: | Huang, K.F, Chiou, S.H, Ko, T.P, Yuann, J.M, Wang, A.H.J. | Deposit date: | 2002-01-21 | Release date: | 2002-07-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | The 1.35 A structure of cadmium-substituted TM-3, a snake-venom metalloproteinase from Taiwan habu: elucidation of a TNFalpha-converting enzyme-like active-site structure with a distorted octahedral geometry of cadmium. Acta Crystallogr.,Sect.D, 58, 2002
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1KUG
| Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with its endogenous inhibitor pENW | Descriptor: | CADMIUM ION, ENW, metalloproteinase | Authors: | Huang, K.F, Chiou, S.H, Ko, T.P, Wang, A.H.J. | Deposit date: | 2002-01-22 | Release date: | 2002-07-10 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues. Eur.J.Biochem., 269, 2002
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1KUI
| Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with pEQW. | Descriptor: | CADMIUM ION, EQW, metalloproteinase | Authors: | Huang, K.F, Chiou, S.H, Ko, T.P, Wang, A.H.J. | Deposit date: | 2002-01-22 | Release date: | 2002-07-10 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues. Eur.J.Biochem., 269, 2002
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2AFM
| Crystal structure of human glutaminyl cyclase at pH 6.5 | Descriptor: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | Authors: | Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J. | Deposit date: | 2005-07-26 | Release date: | 2005-08-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation Proc.Natl.Acad.Sci.Usa, 102, 2005
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2AFX
| Crystal structure of human glutaminyl cyclase in complex with 1-benzylimidazole | Descriptor: | 1-BENZYL-1H-IMIDAZOLE, Glutaminyl-peptide cyclotransferase, SULFATE ION, ... | Authors: | Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J. | Deposit date: | 2005-07-26 | Release date: | 2005-08-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation Proc.Natl.Acad.Sci.Usa, 102, 2005
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2AFO
| Crystal structure of human glutaminyl cyclase at pH 8.0 | Descriptor: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | Authors: | Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J. | Deposit date: | 2005-07-26 | Release date: | 2005-08-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation Proc.Natl.Acad.Sci.Usa, 102, 2005
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2AFW
| Crystal structure of human glutaminyl cyclase in complex with N-acetylhistamine | Descriptor: | Glutaminyl-peptide cyclotransferase, N-[2-(1H-IMIDAZOL-4-YL)ETHYL]ACETAMIDE, SULFATE ION, ... | Authors: | Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J. | Deposit date: | 2005-07-26 | Release date: | 2005-08-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation Proc.Natl.Acad.Sci.Usa, 102, 2005
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2AFZ
| Crystal structure of human glutaminyl cyclase in complex with 1-vinylimidazole | Descriptor: | 1-VINYLIMIDAZOLE, Glutaminyl-peptide cyclotransferase, SULFATE ION, ... | Authors: | Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J. | Deposit date: | 2005-07-26 | Release date: | 2005-08-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation Proc.Natl.Acad.Sci.Usa, 102, 2005
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2AFS
| Crystal structure of the genetic mutant R54W of human glutaminyl cyclase | Descriptor: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | Authors: | Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J. | Deposit date: | 2005-07-26 | Release date: | 2005-08-23 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation Proc.Natl.Acad.Sci.Usa, 102, 2005
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2AFU
| Crystal structure of human glutaminyl cyclase in complex with glutamine t-butyl ester | Descriptor: | Glutaminyl-peptide cyclotransferase, TERT-BUTYL D-ALPHA-GLUTAMINATE, ZINC ION | Authors: | Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J. | Deposit date: | 2005-07-26 | Release date: | 2005-08-23 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation Proc.Natl.Acad.Sci.Usa, 102, 2005
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4MHZ
| Crystal structure of apo-form glutaminyl cyclase from Ixodes scapularis in complex with PBD150 | Descriptor: | 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, Glutaminyl cyclase, putative | Authors: | Huang, K.F, Hsu, H.L, Wang, A.H.J. | Deposit date: | 2013-08-30 | Release date: | 2014-03-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural and functional analyses of a glutaminyl cyclase from Ixodes scapularis reveal metal-independent catalysis and inhibitor binding. Acta Crystallogr.,Sect.D, 70, 2014
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4MHN
| Crystal structure of a glutaminyl cyclase from Ixodes scapularis | Descriptor: | Glutaminyl cyclase, putative, ZINC ION | Authors: | Huang, K.F, Hsu, H.L, Wang, A.H.J. | Deposit date: | 2013-08-30 | Release date: | 2014-03-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Structural and functional analyses of a glutaminyl cyclase from Ixodes scapularis reveal metal-independent catalysis and inhibitor binding. Acta Crystallogr.,Sect.D, 70, 2014
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4MHY
| Crystal structure of a glutaminyl cyclase from Ixodes scapularis in complex with PBD150 | Descriptor: | 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, Glutaminyl cyclase, putative, ... | Authors: | Huang, K.F, Hsu, H.L, Wang, A.H.J. | Deposit date: | 2013-08-30 | Release date: | 2014-03-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Structural and functional analyses of a glutaminyl cyclase from Ixodes scapularis reveal metal-independent catalysis and inhibitor binding. Acta Crystallogr.,Sect.D, 70, 2014
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4MHP
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3VJB
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3VJC
| Crystal structure of the human squalene synthase in complex with zaragozic acid A | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, Squalene synthase, ... | Authors: | Liu, C.I, Jeng, W.Y, Chang, W.J, Ko, T.P, Wang, A.H.J. | Deposit date: | 2011-10-14 | Release date: | 2012-04-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase J.Biol.Chem., 287, 2012
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3VJ9
| Crystal structure of the human squalene synthase | Descriptor: | CALCIUM ION, NICKEL (II) ION, Squalene synthase | Authors: | Liu, C.I, Jeng, W.Y, Chang, W.J, Wang, A.H.J. | Deposit date: | 2011-10-14 | Release date: | 2012-04-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase J.Biol.Chem., 287, 2012
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3VJ8
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3W9D
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3WEF
| Crystal structure of the human squalene synthase in complex with farnesyl thiopyrophosphate | Descriptor: | S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, Squalene synthase | Authors: | Liu, C.I, Jeng, W.Y, Wang, A.H.J. | Deposit date: | 2013-07-07 | Release date: | 2014-02-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural insights into the catalytic mechanism of human squalene synthase. Acta Crystallogr.,Sect.D, 70, 2014
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3WEJ
| Crystal structure of the human squalene synthase F288A mutant in complex with presqualene pyrophosphate | Descriptor: | MAGNESIUM ION, Squalene synthase, {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl}methyl trihydrogen diphosphate | Authors: | Liu, C.I, Jeng, W.Y, Wang, A.H.J. | Deposit date: | 2013-07-07 | Release date: | 2014-02-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into the catalytic mechanism of human squalene synthase. Acta Crystallogr.,Sect.D, 70, 2014
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3X1B
| Crystal structure of laccase from Lentinus sp. at 1.8 A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Jeng, W.Y, Shyur, L.F, Wang, A.H.J. | Deposit date: | 2014-10-31 | Release date: | 2014-12-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of laccase from Lentinus sp. at 1.8 A resolution To be Published
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