4MHZ
Crystal structure of apo-form glutaminyl cyclase from Ixodes scapularis in complex with PBD150
Summary for 4MHZ
Entry DOI | 10.2210/pdb4mhz/pdb |
Related | 4MHN 4MHP 4MHY |
Descriptor | Glutaminyl cyclase, putative, 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea (3 entities in total) |
Functional Keywords | alpha/beta-mixed fold, glutaminyl cyclase, pbd150, secreted protein, transferase |
Biological source | Ixodes scapularis (blacklegged tick,deer tick,shoulder tick) |
Total number of polymer chains | 1 |
Total formula weight | 38129.07 |
Authors | Huang, K.F.,Hsu, H.L.,Wang, A.H.J. (deposition date: 2013-08-30, release date: 2014-03-12, Last modification date: 2023-11-08) |
Primary citation | Huang, K.F.,Hsu, H.L.,Karim, S.,Wang, A.H. Structural and functional analyses of a glutaminyl cyclase from Ixodes scapularis reveal metal-independent catalysis and inhibitor binding. Acta Crystallogr.,Sect.D, 70:789-801, 2014 Cited by PubMed: 24598748DOI: 10.1107/S1399004713033488 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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