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4MHY

Crystal structure of a glutaminyl cyclase from Ixodes scapularis in complex with PBD150

Summary for 4MHY
Entry DOI10.2210/pdb4mhy/pdb
Related4MHN 4MHP 4MHZ
DescriptorGlutaminyl cyclase, putative, ZINC ION, 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, ... (4 entities in total)
Functional Keywordsalpha/beta-mixed fold, glutaminyl cyclase, pbd150, secreted protein, transferase
Biological sourceIxodes scapularis (blacklegged tick,deer tick,shoulder tick)
Total number of polymer chains1
Total formula weight38194.48
Authors
Huang, K.F.,Hsu, H.L.,Wang, A.H.J. (deposition date: 2013-08-30, release date: 2014-03-12, Last modification date: 2023-11-08)
Primary citationHuang, K.F.,Hsu, H.L.,Karim, S.,Wang, A.H.
Structural and functional analyses of a glutaminyl cyclase from Ixodes scapularis reveal metal-independent catalysis and inhibitor binding.
Acta Crystallogr.,Sect.D, 70:789-801, 2014
Cited by
PubMed: 24598748
DOI: 10.1107/S1399004713033488
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.38 Å)
Structure validation

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