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PDB: 815 件

1X24
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Prl-1 (ptp4a)
分子名称: protein tyrosine phosphatase 4a1
著者Zhang, Z.Y, Sun, J.P, Liu, S, Wang, W.Q, Yang, H.
登録日2005-04-20
公開日2005-10-11
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure and Biochemical Properties of PRL-1, a Phosphatase Implicated in Cell Growth, Differentiation, and Tumor Invasion(,)
Biochemistry, 44, 2005
7V4Y
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TTHA1264/TTHA1265 complex
分子名称: Putative zinc protease, ZINC ION, Zinc-dependent peptidase
著者Xu, M, Xu, Q, Ran, T, Wang, W, Sun, B, Wang, Q.
登録日2021-08-16
公開日2022-06-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of TTHA1265 and TTHA1264/TTHA1265 complex reveal an intrinsic heterodimeric assembly.
Int.J.Biol.Macromol., 207, 2022
3PHJ
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Shikimate 5-Dehydrogenase (aroE) from Helicobacter pylori in complex with 3-Dehydroshikimate
分子名称: 3-DEHYDROSHIKIMATE, Shikimate dehydrogenase
著者Cheng, W.C, Lin, S.C, Lin, C.H, Wang, W.C.
登録日2010-11-04
公開日2011-11-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Shikimate 5-Dehydrogenase (aroE) from Helicobacter pylori in complex with 3-Dehydroshikimate
To be Published
8H0O
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Crystal structure of human serum albumin and ruthenium PZA complex adduct
分子名称: Albumin, CHLORIDE ION, NITRIC OXIDE, ...
著者Gong, W.J, Wang, Y, Bai, H.H, Wang, W.M, Wang, H.F.
登録日2022-09-30
公開日2023-10-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.479 Å)
主引用文献Crystal structure of human serum albumin and ruthenium PZA complex adduct
To Be Published
7VIB
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Crystal structure of human ACE2 and GX/P2V RBD
分子名称: Angiotensin-converting enzyme 2, Spike glycoprotein, ZINC ION
著者Guo, Y, Cao, W, Jia, N, Wang, W, Yuan, S, Wang, Y.
登録日2021-09-26
公開日2022-10-05
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of human ACE2 and GX/P2V RBD
To Be Published
3PHH
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Shikimate 5-Dehydrogenase (aroE) from Helicobacter pylori in complex with Shikimate
分子名称: (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, Shikimate dehydrogenase
著者Cheng, W.C, Lin, S.C, Wang, W.C.
登録日2010-11-04
公開日2011-11-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Shikimate 5-Dehydrogenase (aroE) from Helicobacter pylori in complex with Shikimate
To be Published
3PHG
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Crystal structure of the Shikimate 5-Dehydrogenase (aroE) from Helicobacter pylori
分子名称: Shikimate dehydrogenase
著者Cheng, W.C, Lin, S.C, Wang, W.C.
登録日2010-11-04
公開日2011-11-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Crystal structure of the Shikimate 5-Dehydrogenase (aroE) from Helicobacter pylori
To be Published
3PHI
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Shikimate 5-Dehydrogenase (aroE) from Helicobacter pylori in complex with Shikimate and NADPH
分子名称: (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Shikimate dehydrogenase
著者Cheng, W.C, Lin, S.C, Wang, W.C.
登録日2010-11-04
公開日2011-11-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Shikimate 5-Dehydrogenase (aroE) from Helicobacter pylori in complex with Shikimate and NADPH
To be Published
4LC7
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Aminooxazoline inhibitor of BACE-1
分子名称: (3aR,7aR)-3a-[3-(5-chloropyridin-3-yl)phenyl]-3a,4,5,6,7,7a-hexahydro-1,3-benzoxazol-2-amine, Beta-Secretase-1, NICKEL (II) ION
著者Huestis, M.P, Liu, W, Volgraf, M, Purkey, H.E, Wu, C, Wang, W, Smith, D, Vigers, G.P.A, Dutcher, D, Hunt, K.W, Siu, M.
登録日2013-06-21
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Diethylaminosulfur Trifluoride-Mediated Intramolecular Cyclization of 2-hydroxycycloalkylureas to Fused Bicyclic Aminooxazoline Compounds and Evaluation of Their Biochemical Activity Against β-Secretase-1 (BACE-1)
Tetrahedron Lett., 2013
4L7G
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Diethylaminosulfur Trifluoride-Mediated Intramolecular Cyclization of 2-hydroxy-benzylureas to Fused Bicyclic Aminooxazoline Compounds and Evaluation of Their Biochemical Activity Against Beta-Secretase-1 (BACE1)
分子名称: (3aS,7aR)-7a-[3-(pyrimidin-5-yl)phenyl]-3a,6,7,7a-tetrahydro-4H-pyrano[4,3-d][1,3]oxazol-2-amine, Beta-secretase 1, DIMETHYL SULFOXIDE
著者Huestis, M.P, Liu, W, Volgraf, M, Purkey, H, Wang, W, Yu, C, Wu, P, Smith, D, Vigers, G, Dutcher, D, Geck Do, M.K, Hunt, K.W, Siu, M.
登録日2013-06-13
公開日2013-09-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Diethylaminosulfur Trifluoride-Mediated Intramolecular Cyclization of 2-hydroxycycloalkylureas to Fused Bicyclic Aminooxazoline Compounds and Evaluation of Their Biochemical Activity Against β-Secretase-1 (BACE-1)
Tetrahedron Lett., 2013
5VFP
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Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome
分子名称: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ...
著者Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y.
登録日2017-04-09
公開日2018-07-18
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
6D5Y
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Crystal structure of ERK2 G169D mutant
分子名称: Mitogen-activated protein kinase 1
著者Yin, J, Jaiswal, B.S, Wang, W.
登録日2018-04-19
公開日2019-02-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献ERK Mutations and Amplification Confer Resistance to ERK-Inhibitor Therapy.
Clin. Cancer Res., 24, 2018
8WCK
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FCP tetramer in Chaetoceros gracilis
分子名称: (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'- yl acetate, CHLOROPHYLL A, Chlorophyll a/b-binding protein, ...
著者Feng, Y, Li, Z, Zhou, C, Shen, J.-R, Liu, C, Wang, W.
登録日2023-09-12
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (2.71 Å)
主引用文献Structural and spectroscopic insights into fucoxanthin chlorophyll a/c-binding proteins of diatoms in diverse oligomeric states.
Plant Commun., 2024
8WCL
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FCP pentamer in Chaetoceros gracilis
分子名称: (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'- yl acetate, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, CHLOROPHYLL A, ...
著者Feng, Y, Li, Z, Zhou, C, Liu, C, Shen, J.-R, Wang, W.
登録日2023-09-12
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Structural and spectroscopic insights into fucoxanthin chlorophyll a/c-binding proteins of diatoms in diverse oligomeric states.
Plant Commun., 2024
5VFR
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Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome
分子名称: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ...
著者Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y.
登録日2017-04-09
公開日2018-07-18
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
5VFU
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Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome
分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
著者Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y.
登録日2017-04-09
公開日2018-07-18
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
5VFS
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Nucleotide-Driven Triple-State Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome
分子名称: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ...
著者Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y.
登録日2017-04-09
公開日2018-07-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
5VFT
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Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome
分子名称: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ...
著者Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y.
登録日2017-04-09
公開日2018-07-18
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
2XUV
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The structure of HdeB
分子名称: HDEB, SULFATE ION
著者Naismith, J.H, Wang, W.
登録日2010-10-21
公開日2011-08-24
最終更新日2012-01-25
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Salt Bridges Regulate Both Dimer Formation and Monomeric Flexibility in Hdeb and May Have a Role in Periplasmic Chaperone Function.
J.Mol.Biol., 415, 2012
5VFQ
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Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome
分子名称: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ...
著者Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y.
登録日2017-04-09
公開日2018-07-18
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
5VFO
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Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome
分子名称: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ...
著者Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y.
登録日2017-04-08
公開日2018-07-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
3QBE
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Crystal structure of the 3-Dehydroquinate Synthase (aroB) from Mycobacterium tuberculosis
分子名称: 3-dehydroquinate synthase, CHLORIDE ION, ZINC ION
著者Cheng, W.C, Wen, Y.H, Wang, W.C.
登録日2011-01-13
公開日2012-01-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Crystal structure of the 3-Dehydroquinate Synthase (aroB) from Mycobacterium tuberculosis
To be Published
4L7J
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Diethylaminosulfur Trifluoride-Mediated Intramolecular Cyclization of 2-hydroxy-benzylureas to Fused Bicyclic Aminooxazoline Compounds and Evaluation of Their Biochemical Activity Against Beta-Secretase-1 (BACE-1)
分子名称: 2-[(3aS,7aR)-2-amino-3a-(2,4-difluorophenyl)-3a,6,7,7a-tetrahydro[1,3]oxazolo[4,5-c]pyridin-5(4H)-yl]pyridine-3-carbonitrile, ACETATE ION, Beta-secretase 1
著者Huestis, M.P, Liu, W, Volgraf, M, Purkey, H.E, Wang, W, Yu, C, Wu, P, Smith, D, Vigers, G, Dutcher, D, Geck Do, M.K, Hunt, K.W, Siu, M.
登録日2013-06-13
公開日2013-09-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.651 Å)
主引用文献Diethylaminosulfur Trifluoride-Mediated Intramolecular Cyclization of 2-hydroxycycloalkylureas to Fused Bicyclic Aminooxazoline Compounds and Evaluation of Their Biochemical Activity Against β-Secretase-1 (BACE-1)
Tetrahedron Lett., 2013
4L7H
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Diethylaminosulfur Trifluoride-Mediated Intramolecular Cyclization of 2-hydroxy-benzylureas to Fused Bicyclic Aminooxazoline Compounds and Evaluation of Their Biochemical Activity Against Beta-Secretase-1 (BACE-1)
分子名称: 2-[(3aR,7aR)-2-amino-7a-(2,4-difluorophenyl)-3a,6,7,7a-tetrahydro[1,3]oxazolo[5,4-c]pyridin-5(4H)-yl]pyridine-3-carbonitrile, ACETATE ION, Beta-secretase 1, ...
著者Huestis, M.P, Liu, W, Volgraf, M, Purkey, H.E, Wang, W, Yu, C, Wu, P, Smith, D, Vigers, G, Dutcher, D, Geck Do, M.K, Hunt, K.W, Siu, M.
登録日2013-06-13
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Diethylaminosulfur Trifluoride-Mediated Intramolecular Cyclization of 2-hydroxycycloalkylureas to Fused Bicyclic Aminooxazoline Compounds and Evaluation of Their Biochemical Activity Against β-Secretase-1 (BACE-1)
Tetrahedron Lett., 2013
7KED
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RNA polymerase II elongation complex with unnatural base dTPT3
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Oh, J, Wang, W, Wang, D.
登録日2020-10-10
公開日2021-06-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II.
Nat.Chem.Biol., 17, 2021

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