8HRN
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![BU of 8hrn by Molmil](/molmil-images/mine/8hrn) | Cryo-EM structure of ACE2 | 分子名称: | Angiotensin-converting enzyme 2 | 著者 | Xu, J, Liu, N, Wang, H.W. | 登録日 | 2022-12-15 | 公開日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Self-assembled monolayers guided free-standing atomic-crystal/molecule superstructure To Be Published
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8HRL
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![BU of 8hrl by Molmil](/molmil-images/mine/8hrl) | SARS-CoV-2 Delta S-RBD-ACE2 | 分子名称: | Processed angiotensin-converting enzyme 2, Spike protein S1 | 著者 | Xu, J, Meng, F, Liu, N, Wang, H.W. | 登録日 | 2022-12-15 | 公開日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Self-assembled monolayers guided free-standing atomic-crystal/molecule superstructure To Be Published
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4LH6
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![BU of 4lh6 by Molmil](/molmil-images/mine/4lh6) | Crystal structure of a LigA inhibitor | 分子名称: | 4-amino-2-bromothieno[3,2-c]pyridine-7-carboxamide, ACETATE ION, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, ... | 著者 | Benenato, K, Wang, H, Mcguire, H.M, Davis, H, Gao, N, Prince, D.B, Jahic, H, Stokes, S.S, Boriack-Sjodin, P.A. | 登録日 | 2013-06-30 | 公開日 | 2013-12-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Identification through structure-based methods of a bacterial NAD(+)-dependent DNA ligase inhibitor that avoids known resistance mutations. Bioorg.Med.Chem.Lett., 24, 2014
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3B57
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![BU of 3b57 by Molmil](/molmil-images/mine/3b57) | Crystal structure of the Lin1889 protein (Q92AN1) from Listeria innocua. Northeast Structural Consortium target LkR65 | 分子名称: | Lin1889 protein, MAGNESIUM ION | 著者 | Kuzin, A.P, Abashidze, M, Seetharaman, J, Benach, J, Forouhar, F, Vorobiev, S.M, Wang, H, Janjua, H, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-10-25 | 公開日 | 2007-11-06 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of the Lin1889 protein (Q92AN1) from Listeria innocua. To be Published
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4E0A
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![BU of 4e0a by Molmil](/molmil-images/mine/4e0a) | Crystal Structure of the mutant F44R BH1408 protein from Bacillus halodurans, Northeast Structural Genomics Consortium (NESG) Target BhR182 | 分子名称: | ACETIC ACID, BH1408 protein, GLYCEROL, ... | 著者 | Kuzin, A, Neely, H, Seetharaman, J, Patel, P, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2012-03-02 | 公開日 | 2012-05-02 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target BhR182 To be Published
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8HXX
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3E1E
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![BU of 3e1e by Molmil](/molmil-images/mine/3e1e) | Crystal structure of a Thioesterase family protein from Silicibacter pomeroyi. NorthEast Structural Genomics target SiR180A | 分子名称: | Thioesterase family protein | 著者 | Seetharaman, J, Abashidze, M, Wang, H, Janjua, H, Foote, E.L, Xiao, R, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-08-04 | 公開日 | 2008-09-30 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of a Thioesterase family protein from Silicibacter pomeroyi. NorthEast Structural Genomics target SiR180A To be Published
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2K8U
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![BU of 2k8u by Molmil](/molmil-images/mine/2k8u) | Solution NMR structure of trans-4-hydroxynonenal derived dG adduct of (6S,8R,11S)-configuration matched with dC | 分子名称: | (2S,5R)-5-pentyltetrahydrofuran-2-ol, 5'-D(*DGP*DCP*DTP*DAP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DCP*DTP*DCP*DGP*DCP*DTP*DAP*DGP*DC)-3' | 著者 | Huang, H, Wang, H, Qi, N, Lloyd, R.S, Rizzo, C.J, Stone, M.P. | 登録日 | 2008-09-23 | 公開日 | 2008-11-04 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The stereochemistry of trans-4-hydroxynonenal-derived exocyclic 1,N2-2'-deoxyguanosine adducts modulates formation of interstrand cross-links in the 5'-CpG-3' sequence. Biochemistry, 47, 2008
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4ICZ
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![BU of 4icz by Molmil](/molmil-images/mine/4icz) | HER2 1221/1222 phosphorylation regulated by PTPN9 | 分子名称: | HER2, Tyrosine-protein phosphatase non-receptor type 9 | 著者 | Xu, Y.F, Wang, H.M, Liu, C.H, Yu, X, Sun, J.P. | 登録日 | 2012-12-11 | 公開日 | 2013-12-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | HER2 1221/1222 phosphorylation regulated by PTPN9 To be Published
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2YY0
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![BU of 2yy0 by Molmil](/molmil-images/mine/2yy0) | Crystal Structure of MS0802, c-Myc-1 binding protein domain from Homo sapiens | 分子名称: | C-Myc-binding protein | 著者 | Xie, Y, Wang, H, Ihsanawati, K.T, Kishishita, S, Takemoto, C, Shirozu, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-27 | 公開日 | 2008-04-29 | 最終更新日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | crystal structure of c-Myc-1 binding protein domain from Homo sapiens To be Published
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4KUD
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![BU of 4kud by Molmil](/molmil-images/mine/4kud) | Crystal structure of N-terminal acetylated Sir3 BAH domain D205N mutant in complex with yeast nucleosome core particle | 分子名称: | Histone H2A.2, Histone H2B.1, Histone H3, ... | 著者 | Yang, D, Fang, Q, Wang, M, Ren, R, Wang, H, He, M, Sun, Y, Yang, N, Xu, R.M. | 登録日 | 2013-05-22 | 公開日 | 2013-08-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.203 Å) | 主引用文献 | N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain. Nat.Struct.Mol.Biol., 20, 2013
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2WOE
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![BU of 2woe by Molmil](/molmil-images/mine/2woe) | Crystal Structure of the D97N variant of dinitrogenase reductase- activating glycohydrolase (DRAG) from Rhodospirillum rubrum in complex with ADP-ribose | 分子名称: | ADP-RIBOSYL-[DINITROGEN REDUCTASE] GLYCOHYDROLASE, GLYCEROL, L(+)-TARTARIC ACID, ... | 著者 | Berthold, C.L, Wang, H, Nordlund, S, Hogbom, M. | 登録日 | 2009-07-23 | 公開日 | 2009-08-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanism of Adp-Ribosylation Removal Revealed by the Structure and Ligand Complexes of the Dimanganese Mono-Adp-Ribosylhydrolase Drag. Proc.Natl.Acad.Sci.USA, 106, 2009
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4H58
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![BU of 4h58 by Molmil](/molmil-images/mine/4h58) | BRAF in complex with compound 3 | 分子名称: | CHLORIDE ION, N-(4-{[(2-methoxyethyl)amino]methyl}phenyl)-6-(pyridin-4-yl)quinazolin-2-amine, Serine/threonine-protein kinase B-raf | 著者 | Vasbinder, M, Aquila, B, Augustin, M, Chueng, T, Cook, D, Drew, L, Fauber, B, Glossop, S, Godin, R, Grondine, M, Hennessy, E, Johannes, J, Lee, S, Lyne, P, Moertl, M, Omer, C, Palakurthi, S, Pontz, T, Read, J, Sha, L, Shen, M, Steinbacher, S, Wang, H, Wu, A, Ye, M, Bagal, B. | 登録日 | 2012-09-18 | 公開日 | 2013-02-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Discovery and Optimization of a Novel Series of Potent Mutant B-Raf(V600E) Selective Kinase Inhibitors. J.Med.Chem., 56, 2013
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5ZAM
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![BU of 5zam by Molmil](/molmil-images/mine/5zam) | Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate | 分子名称: | Endoribonuclease Dicer, RISC-loading complex subunit TARBP2, RNA (73-mer) | 著者 | Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. | 登録日 | 2018-02-07 | 公開日 | 2018-05-09 | 最終更新日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | 主引用文献 | Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate. Cell, 173, 2018
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2WOD
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![BU of 2wod by Molmil](/molmil-images/mine/2wod) | Crystal Structure of the dinitrogenase reductase-activating glycohydrolase (DRAG) from Rhodospirillum rubrum in complex with ADP- ribsoyllysine | 分子名称: | ADP-RIBOSYL-[DINITROGEN REDUCTASE] GLYCOHYDROLASE, CHLORIDE ION, GLYCEROL, ... | 著者 | Berthold, C.L, Wang, H, Nordlund, S, Hogbom, M. | 登録日 | 2009-07-23 | 公開日 | 2009-08-11 | 最終更新日 | 2018-01-17 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Mechanism of Adp-Ribosylation Removal Revealed by the Structure and Ligand Complexes of the Dimanganese Mono-Adp-Ribosylhydrolase Drag. Proc.Natl.Acad.Sci.USA, 106, 2009
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2KAS
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![BU of 2kas by Molmil](/molmil-images/mine/2kas) | HNE-dG adduct mismatched with dA in basic solution | 分子名称: | (4S)-nonane-1,4-diol, 5'-D(*DGP*DCP*DTP*DAP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DCP*DTP*DAP*DGP*DCP*DTP*DAP*DGP*DC)-3' | 著者 | Huang, H, Wang, H, Lloyd, R.S, Rizzo, C.J, Stone, M.P. | 登録日 | 2008-11-13 | 公開日 | 2009-05-26 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformational interconversion of the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N(2)-deoxyguanosine adduct when mismatched with deoxyadenosine in DNA Chem.Res.Toxicol., 22, 2009
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5F7H
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![BU of 5f7h by Molmil](/molmil-images/mine/5f7h) | Human T-cell immunoglobulin and mucin domain protein 4 (hTIM-4) complex with phosphoserine | 分子名称: | CALCIUM ION, PHOSPHOSERINE, T-cell immunoglobulin and mucin domain-containing protein 4 | 著者 | Gao, G.F, Lu, G, Wang, H, Qi, J. | 登録日 | 2015-12-08 | 公開日 | 2016-02-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of human TIM members: Ebolavirus entry-enhancing receptors Chin.Sci.Bull., 60, 2015
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1YD1
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![BU of 1yd1 by Molmil](/molmil-images/mine/1yd1) | Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima bound to its catalytic divalent cation: magnesium | 分子名称: | GLYCEROL, MAGNESIUM ION, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
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1YD5
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![BU of 1yd5 by Molmil](/molmil-images/mine/1yd5) | Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima: Point mutant N88A bound to its catalytic divalent cation | 分子名称: | MANGANESE (II) ION, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
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1YD4
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![BU of 1yd4 by Molmil](/molmil-images/mine/1yd4) | Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima: Point mutant Y29F bound to its catalytic divalent cation | 分子名称: | MANGANESE (II) ION, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
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2K8T
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![BU of 2k8t by Molmil](/molmil-images/mine/2k8t) | Solution NMR structure of trans-4-hydroxynonenal derived dG adduct of (6R,8S,11R)-configuration opposite dC | 分子名称: | (2S,5R)-5-pentyltetrahydrofuran-2-ol, 5'-D(*DGP*DCP*DTP*DAP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DCP*DTP*DCP*DGP*DCP*DTP*DAP*DGP*DC)-3' | 著者 | Huang, H, Wang, H, Qi, N, Lloyd, R.S, Rizzo, C.J, Stone, M.P. | 登録日 | 2008-09-23 | 公開日 | 2008-11-04 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The stereochemistry of trans-4-hydroxynonenal-derived exocyclic 1,N2-2'-deoxyguanosine adducts modulates formation of interstrand cross-links in the 5'-CpG-3' sequence. Biochemistry, 47, 2008
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2KAR
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![BU of 2kar by Molmil](/molmil-images/mine/2kar) | HNE-dG adduct mismatched with dA in acidic solution | 分子名称: | (4S)-nonane-1,4-diol, 5'-D(*DGP*DCP*DTP*DAP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DCP*DTP*DAP*DGP*DCP*DTP*DAP*DGP*DC)-3' | 著者 | Huang, H, Wang, H, Lloyd, R.S, Rizzo, C.J, Stone, M.P. | 登録日 | 2008-11-13 | 公開日 | 2009-05-26 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformational interconversion of the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N(2)-deoxyguanosine adduct when mismatched with deoxyadenosine in DNA Chem.Res.Toxicol., 22, 2009
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3GGN
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![BU of 3ggn by Molmil](/molmil-images/mine/3ggn) | Crystal structure of DR_A0006 from Deinococcus radiodurans. Northeast Structural Genomics Consortium Target DrR147D | 分子名称: | Uncharacterized protein DR_A0006 | 著者 | Seetharaman, J, Neely, H, Wang, H, Janjua, H, Foote, E.L, Xiao, R, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-02-28 | 公開日 | 2009-03-24 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of DR_A0006 from Deinococcus radiodurans. To be Published
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1YD0
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![BU of 1yd0 by Molmil](/molmil-images/mine/1yd0) | Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima bound to its catalytic divalent cation: manganese | 分子名称: | GLYCEROL, MANGANESE (II) ION, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
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3GAD
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![BU of 3gad by Molmil](/molmil-images/mine/3gad) | Structure of apomif | 分子名称: | ACETIC ACID, Macrophage migration inhibitory factor-like protein, SULFATE ION | 著者 | Zhou, Y.-F, Su, X.-D, Shao, D, Wang, H. | 登録日 | 2009-02-17 | 公開日 | 2009-12-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and functional comparison of MIF ortholog from Plasmodium yoelii with MIF from its rodent host Mol.Immunol., 47, 2010
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