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PDB: 11 件
2A3D
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BU of 2a3d by Molmil
SOLUTION STRUCTURE OF A DE NOVO DESIGNED SINGLE CHAIN THREE-HELIX BUNDLE (A3D)
分子名称: PROTEIN (DE NOVO THREE-HELIX BUNDLE)
著者Walsh, S.T.R, Cheng, H, Bryson, J.W, Roder, H, Degrado, W.F.
登録日1999-04-01
公開日1999-05-05
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of a de novo designed three-helix bundle protein.
Proc.Natl.Acad.Sci.USA, 96, 1999
7S5B
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BU of 7s5b by Molmil
Unbound State of a De novo designed Protein Binder to the Human Interleukin-7 Receptor
分子名称: Miniprotein Binder
著者Walsh, S.T.R, Cao, L, Baker, D.
登録日2021-09-10
公開日2022-05-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
6P67
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Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha 2B8 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-IL-7R 2B8 Fab heavy chain, ...
著者Walsh, S.T.R, Kashi, L, Kohnhorst, C.L.
登録日2019-06-03
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models.
Leukemia, 34, 2020
6P4Y
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Crystal Structure of anti-IL-7Ralpha 4A10 Fab
分子名称: 4A10 Fab heavy chain, 4A10 Fab light chain
著者Walsh, S.T.R, Kashi, L, Kohnhorst, C.L.
登録日2019-05-29
公開日2019-09-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models.
Leukemia, 34, 2020
6P50
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Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha Fab 4A10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-7 receptor subunit alpha, anti-IL-7R 4A10 Fab heavy chain, ...
著者Walsh, S.T.R, Kashi, L, Kohnhorst, C.L.
登録日2019-05-29
公開日2019-09-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models.
Leukemia, 34, 2020
1Z7C
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BU of 1z7c by Molmil
Crystal Structure of Human Placental Lactogen
分子名称: Chorionic somatomammotropin hormone
著者Walsh, S.T.R, Kossiakoff, A.A.
登録日2005-03-24
公開日2006-03-07
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure and Site 1 Binding Energetics of Human Placental Lactogen.
J.Mol.Biol., 358, 2006
3JUY
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BU of 3juy by Molmil
Crystal Structure of a 3B3 Variant, a Broadly Neutralizing HIV-1 scFv Antibody
分子名称: 3B3 single chain variant HIV-1 antibody
著者Clark, K.R, Walsh, S.T.
登録日2009-09-15
公開日2009-12-08
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of a 3B3 variant-A broadly neutralizing HIV-1 scFv antibody.
Protein Sci., 18, 2009
3UP1
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BU of 3up1 by Molmil
Crystal structure of the unliganded human interleukin-7 receptor extracellular domain
分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者McElroy, C.A, Holland, P.J, Walsh, S.T.R.
登録日2011-11-17
公開日2012-02-08
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural reorganization of the interleukin-7 signaling complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
3DI2
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BU of 3di2 by Molmil
Crystal structure of the complex of human interleukin-7 with unglycosylated human interleukin-7 receptor alpha ectodomain
分子名称: Interleukin-7, Interleukin-7 receptor subunit alpha, PENTAETHYLENE GLYCOL
著者McElroy, C.A, Dohm, J.A, Walsh, S.T.R.
登録日2008-06-19
公開日2009-01-27
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and Biophysical Studies of the Human IL-7/IL-7Ralpha Complex.
Structure, 17, 2009
3DI3
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BU of 3di3 by Molmil
Crystal structure of the complex of human interleukin-7 with glycosylated human interleukin-7 receptor alpha ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-7, Interleukin-7 receptor subunit alpha
著者McElroy, C.A, Dohm, J.A, Walsh, S.T.R.
登録日2008-06-19
公開日2009-01-27
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and Biophysical Studies of the Human IL-7/IL-7Ralpha Complex.
Structure, 17, 2009
1KF9
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PHAGE DISPLAY DERIVED VARIANT OF HUMAN GROWTH HORMONE COMPLEXED WITH TWO COPIES OF THE EXTRACELLULAR DOMAIN OF ITS RECEPTOR
分子名称: EXTRACELLULAR DOMAIN HUMAN GROWTH HORMONE RECEPTOR (1-238), PHAGE DISPLAY DERIVED VARIANT HUMAN GROWTH HORMONE
著者Schiffer, C.A, Ultsch, M, Walsh, S, Somers, W, De Vos, A.M, Kossiakoff, A.A.
登録日2001-11-19
公開日2002-11-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of a Phage Display Derived Variant of Human Growth Hormone Complexed to Two Copies of the Extracellular Domain of its Receptor: Evidence for Strong Structural Coupling between Receptor Binding Sites
J.Mol.Biol., 316, 2002

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件を2024-07-03に公開中

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