8PFG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8pfg by Molmil](/molmil-images/mine/8pfg) | autoinhibited RfaH bound to E. coli transcription complex paused at ops site (encounter complex), not fully complementary scaffold | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | Deposit date: | 2023-06-15 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
|
|
8PIB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8pib by Molmil](/molmil-images/mine/8pib) | autoinhibited RfaH bound to E. coli transcription complex paused at ops site (encounter complex) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | Deposit date: | 2023-06-21 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
|
|
8PIM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8pim by Molmil](/molmil-images/mine/8pim) | fully recruited RfaH bound to E. coli transcription complex paused at ops site (not complementary scaffold) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | Deposit date: | 2023-06-22 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
|
|
8PHK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8phk by Molmil](/molmil-images/mine/8phk) | fully recruited RfaH bound to E. coli transcription complex paused at ops site | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | Deposit date: | 2023-06-20 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
|
|
4RZ9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rz9 by Molmil](/molmil-images/mine/4rz9) | Pre-mRNA-splicing factor 38A AS 1-179 | Descriptor: | Pre-mRNA-splicing factor 38A | Authors: | Schuetze, T, Weber, G, Wahl, M.C. | Deposit date: | 2014-12-19 | Release date: | 2015-12-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | The N-terminal domain of the unusual SR protein hPrp38 is an interaction hub in the spliceosome To be Published
|
|
4RKE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rke by Molmil](/molmil-images/mine/4rke) | Drosophila melanogaster Rab2 bound to GMPPNP | Descriptor: | GH01619p, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | Authors: | Lardong, J.A, Driller, J.H, Depner, H, Weise, C, Petzoldt, A, Wahl, M.C, Sigrist, S.J, Loll, B. | Deposit date: | 2014-10-13 | Release date: | 2014-12-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.0006 Å) | Cite: | Structures of Drosophila melanogaster Rab2 and Rab3 bound to GMPPNP. Acta Crystallogr F Struct Biol Commun, 71, 2015
|
|
4RVQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rvq by Molmil](/molmil-images/mine/4rvq) | PWI-like domain of Chaetomium thermophilum Brr2 | Descriptor: | 1,2-ETHANEDIOL, Pre-mRNA splicing helicase-like protein, SULFATE ION | Authors: | Absmeier, E, Rosenberger, L, Santos, K.F, Becke, C, Wahl, M.C. | Deposit date: | 2014-11-27 | Release date: | 2015-04-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.135 Å) | Cite: | A noncanonical PWI domain in the N-terminal helicase-associated region of the spliceosomal Brr2 protein. Acta Crystallogr.,Sect.D, 71, 2015
|
|
4RZA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rza by Molmil](/molmil-images/mine/4rza) | Pre-mRNA-splicing factor 38A AS 1-205 | Descriptor: | Pre-mRNA-splicing factor 38A | Authors: | Schuetze, T, Ulrich, A, Wahl, M.C. | Deposit date: | 2014-12-19 | Release date: | 2015-12-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The N-terminal domain of the unusual SR protein hPrp38 is an interaction hub in the spliceosome To be Published
|
|
3LSA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lsa by Molmil](/molmil-images/mine/3lsa) | Padron0.9-OFF (non-fluorescent state) | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Padron0.9, ... | Authors: | Brakemann, T, Weber, G, Trowitzsch, S, Wahl, M.C, Jakobs, S. | Deposit date: | 2010-02-12 | Release date: | 2010-03-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron. J.Biol.Chem., 285, 2010
|
|
3LS3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ls3 by Molmil](/molmil-images/mine/3ls3) | Padron0.9-ON (fluorescent state) | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Padron0.9, ... | Authors: | Brakemann, T, Weber, G, Trowitzsch, S, Wahl, M.C, Jakobs, S. | Deposit date: | 2010-02-12 | Release date: | 2010-03-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron. J.Biol.Chem., 285, 2010
|
|
4PSM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4psm by Molmil](/molmil-images/mine/4psm) | Crystal structure of pfuThermo-DBP-RP1 (crystal form II) | Descriptor: | SULFATE ION, ssDNA binding protein | Authors: | Gahlei, H, von Moeller, H, Eppers, D, Loll, B, Wahl, M.C. | Deposit date: | 2014-03-07 | Release date: | 2014-04-30 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Entrapment of DNA in an intersubunit tunnel system of a single-stranded DNA-binding protein. Nucleic Acids Res., 42, 2014
|
|
4PSN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4psn by Molmil](/molmil-images/mine/4psn) | Crystal structure of apeThermo-DBP-RP2 | Descriptor: | GLYCEROL, IMIDAZOLE, ssDNA binding protein | Authors: | Gahlei, H, von Moeller, H, Eppers, D, Loll, B, Wahl, M.C. | Deposit date: | 2014-03-07 | Release date: | 2014-04-30 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Entrapment of DNA in an intersubunit tunnel system of a single-stranded DNA-binding protein. Nucleic Acids Res., 42, 2014
|
|
4PSL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4psl by Molmil](/molmil-images/mine/4psl) | Crystal structure of pfuThermo-DBP-RP1 (crystal form I) | Descriptor: | SULFATE ION, ssDNA binding protein | Authors: | Gahlei, H, von Moeller, H, Eppers, D, Sohmen, D, Wilson, D.N, Loll, B, Wahl, M.C. | Deposit date: | 2014-03-07 | Release date: | 2014-04-30 | Last modified: | 2014-06-25 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Entrapment of DNA in an intersubunit tunnel system of a single-stranded DNA-binding protein. Nucleic Acids Res., 42, 2014
|
|
4PSO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pso by Molmil](/molmil-images/mine/4pso) | Crystal structure of apeThermo-DBP-RP2 bound to ssDNA dT10 | Descriptor: | PHOSPHATE ION, polydeoxyribonucleotide, ssDNA binding protein | Authors: | Gahlei, H, von Moeller, H, Eppers, D, Loll, B, Wahl, M.C. | Deposit date: | 2014-03-07 | Release date: | 2014-04-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Entrapment of DNA in an intersubunit tunnel system of a single-stranded DNA-binding protein. Nucleic Acids Res., 42, 2014
|
|
4R3E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r3e by Molmil](/molmil-images/mine/4r3e) | |
6S8Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s8q by Molmil](/molmil-images/mine/6s8q) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 | Descriptor: | Pre-mRNA-processing-splicing factor 8, SULFATE ION, U5 small nuclear ribonucleoprotein 200 kDa helicase | Authors: | Santos, K.F, Vester, K, Wahl, M.C. | Deposit date: | 2019-07-10 | Release date: | 2020-01-22 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.391 Å) | Cite: | The inactive C-terminal cassette of the dual-cassette RNA helicase BRR2 both stimulates and inhibits the activity of the N-terminal helicase unit. J.Biol.Chem., 295, 2020
|
|
6S9I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s9i by Molmil](/molmil-images/mine/6s9i) | |
6TQN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tqn by Molmil](/molmil-images/mine/6tqn) | rrn anti-termination complex without S4 | Descriptor: | 30S ribosomal protein S10, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N. | Deposit date: | 2019-12-17 | Release date: | 2020-08-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis. Mol.Cell, 79, 2020
|
|
6TEO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6teo by Molmil](/molmil-images/mine/6teo) | Crystal structure of a yeast Snu114-Prp8 complex | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-splicing factor 8, ... | Authors: | Ganichkin, O, Jia, J, Loll, B, Absmeier, E, Wahl, M.C. | Deposit date: | 2019-11-12 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | A Snu114-GTP-Prp8 module forms a relay station for efficient splicing in yeast. Nucleic Acids Res., 48, 2020
|
|
6S8O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s8o by Molmil](/molmil-images/mine/6s8o) | Human Brr2 Helicase Region M641C/A1582C | Descriptor: | U5 small nuclear ribonucleoprotein 200 kDa helicase | Authors: | Vester, K, Santos, K.F, Wahl, M.C. | Deposit date: | 2019-07-10 | Release date: | 2020-01-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.172 Å) | Cite: | The inactive C-terminal cassette of the dual-cassette RNA helicase BRR2 both stimulates and inhibits the activity of the N-terminal helicase unit. J.Biol.Chem., 295, 2020
|
|
6TW2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tw2 by Molmil](/molmil-images/mine/6tw2) | Re-refined crystal structure of di-phosphorylated human CLK1 in complex with a novel substituted indole inhibitor | Descriptor: | Dual specificity protein kinase CLK1, ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate | Authors: | Loll, B, Haltenhof, T, Heyd, F, Wahl, M.C. | Deposit date: | 2020-01-12 | Release date: | 2020-02-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Conserved Kinase-Based Body-Temperature Sensor Globally Controls Alternative Splicing and Gene Expression. Mol.Cell, 78, 2020
|
|
6TQO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tqo by Molmil](/molmil-images/mine/6tqo) | rrn anti-termination complex | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S4, DNA-directed RNA polymerase subunit alpha, ... | Authors: | Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N. | Deposit date: | 2019-12-17 | Release date: | 2020-08-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis. Mol.Cell, 79, 2020
|
|
6ZWX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zwx by Molmil](/molmil-images/mine/6zwx) | Crystal structure of E. coli RNA helicase HrpA | Descriptor: | ATP-dependent RNA helicase HrpA | Authors: | Grass, L.M, Wollenhaupt, J, Barthel, T, Loll, B, Wahl, M.C. | Deposit date: | 2020-07-29 | Release date: | 2021-06-30 | Last modified: | 2021-08-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
6ZWW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zww by Molmil](/molmil-images/mine/6zww) | Crystal structure of E. coli RNA helicase HrpA in complex with RNA | Descriptor: | ATP-dependent RNA helicase HrpA, CALCIUM ION, ssRNA | Authors: | Grass, L.M, Wollenhaupt, J, Barthel, T, Loll, B, Wahl, M.C. | Deposit date: | 2020-07-29 | Release date: | 2021-06-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.16 Å) | Cite: | Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7B3A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7b3a by Molmil](/molmil-images/mine/7b3a) | Crystal structure of PamZ | Descriptor: | ACETATE ION, ACETYL COENZYME *A, CHLORIDE ION, ... | Authors: | Loll, B, Dang, T, Mainz, A, Suessmuth, R, Wahl, M.C. | Deposit date: | 2020-11-30 | Release date: | 2021-11-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Molecular basis of antibiotic self-resistance in a bee larvae pathogen. Nat Commun, 13, 2022
|
|