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PDB: 578 results

2OF5
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BU of 2of5 by Molmil
Oligomeric Death Domain complex
Descriptor: Death domain-containing protein CRADD, Leucine-rich repeat and death domain-containing protein
Authors:Park, H.H, Logette, E, Raunser, S, Cuenin, S, Walz, T, Tschopp, J, Wu, H.
Deposit date:2007-01-02
Release date:2007-04-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Death domain assembly mechanism revealed by crystal structure of the oligomeric PIDDosome core complex.
Cell(Cambridge,Mass.), 128, 2007
6WWZ
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BU of 6wwz by Molmil
Cryo-EM structure of the human chemokine receptor CCR6 in complex with CCL20 and a Go protein
Descriptor: C-C chemokine receptor type 6,C-C chemokine receptor type 6, C-C motif chemokine 20, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Wasilko, D.J, Johnson, Z.L, Ammirati, M, Han, S, Wu, H.
Deposit date:2020-05-09
Release date:2020-06-24
Last modified:2020-07-01
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20.
Nat Commun, 11, 2020
5V9I
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BU of 5v9i by Molmil
Crystal structure of catalytic domain of G9a with MS0105
Descriptor: GLYCEROL, Histone-lysine N-methyltransferase EHMT2, N~2~-cyclohexyl-N~4~-(1-ethylpiperidin-4-yl)-6,7-dimethoxy-N~2~-methylquinazoline-2,4-diamine, ...
Authors:Dong, A, Zeng, H, Liu, J, Xiong, Y, Babault, N, Jin, J, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Wu, H, Brown, P.J, Structural Genomics Consortium (SGC)
Deposit date:2017-03-23
Release date:2018-03-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of catalytic domain of G9a with MS0105
to be published
6W8N
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BU of 6w8n by Molmil
Structure of a trans-membrane protein
Descriptor: Endosomal/lysosomal potassium channel TMEM175
Authors:Shen, C, Fu, T.M, Wang, L.F, Rawson, S, Wu, H.
Deposit date:2020-03-20
Release date:2021-08-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of a trans-membrane protein
To Be Published
6W8P
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BU of 6w8p by Molmil
Structure of membrane protein with ions
Descriptor: Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION
Authors:Shen, C, Fu, T.M, Wang, L.F, Rawson, S, Wu, H.
Deposit date:2020-03-21
Release date:2021-08-04
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of membrane protein with ions
To Be Published
6W8O
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BU of 6w8o by Molmil
Structure of an Apo membrane protein
Descriptor: Endosomal/lysosomal potassium channel TMEM175
Authors:Shen, C, Fu, T.M, Wang, L.F, Rawson, S, Wu, H.
Deposit date:2020-03-20
Release date:2021-08-04
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of an Apo membrane protein
To Be Published
5VBB
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BU of 5vbb by Molmil
Human RNA Pseudouridylate Synthase Domain Containing 1
Descriptor: CHLORIDE ION, GLYCEROL, RNA pseudouridylate synthase domain-containing protein 1, ...
Authors:DONG, A, ZENG, H, WALKER, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, WU, H, Structural Genomics Consortium (SGC)
Deposit date:2017-03-29
Release date:2017-04-19
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Human RNA Pseudouridylate Synthase Domain Containing 1
to be published
5WCI
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BU of 5wci by Molmil
Human MYST histone acetyltransferase 1
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Histone acetyltransferase KAT8, ...
Authors:Dong, A, Zeng, H, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Zheng, Y.G, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC)
Deposit date:2017-06-30
Release date:2017-07-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Human MYST histone acetyltransferase 1
to be published
5WCG
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BU of 5wcg by Molmil
SET and MYND Domain Containing protein 2
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIMETHYL SULFOXIDE, N-lysine methyltransferase SMYD2, ...
Authors:Dong, A, Zeng, H, Walker, J.R, Hutch, A, Seitova, A, Tatlock, J, Kumpf, R, Owen, A, Taylor, A, Casimiro-Garcia, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC)
Deposit date:2017-06-30
Release date:2017-08-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:The crystal structure of SMYD2 in complex with compound MTF003
to be published
2PWP
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BU of 2pwp by Molmil
Crystal structure of spermidine synthase from Plasmodium falciparum in complex with spermidine
Descriptor: GLYCEROL, SPERMIDINE, SULFATE ION, ...
Authors:Qiu, W, Dong, A, Ren, H, Wu, H, Zhao, Y, Schapira, M, Wasney, G, Vedadi, M, Lew, J, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Plotnikov, A.N, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC)
Deposit date:2007-05-11
Release date:2007-05-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of spermidine synthase from Plasmodium falciparum in complex with spermidine.
To be Published
3M0A
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BU of 3m0a by Molmil
Crystal structure of TRAF2:cIAP2 complex
Descriptor: Baculoviral IAP repeat-containing protein 3, TNF receptor-associated factor 2, ZINC ION
Authors:Kabaleeswaran, V, Wu, H.
Deposit date:2010-03-02
Release date:2010-04-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation.
Mol.Cell, 38, 2010
2PXX
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BU of 2pxx by Molmil
Human putative methyltransferase MGC2408
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, UNKNOWN ATOM OR ION, Uncharacterized protein MGC2408
Authors:Tempel, W, Wu, H, Dombrovsky, L, Zeng, H, Zhu, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2007-05-14
Release date:2007-05-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:An intact SAM-dependent methyltransferase fold is encoded by the human endothelin-converting enzyme-2 gene.
Proteins, 74, 2009
3QKJ
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BU of 3qkj by Molmil
The PWWP domain of human DNA (CYTOSINE-5-)-METHYLTRANSFERASE 3 BETA in complex with a bis-tris molecule
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA cytosine-5 methyltransferase 3 beta isoform 6 variant, SULFATE ION
Authors:Zeng, H, Amaya, M.F, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC)
Deposit date:2011-02-01
Release date:2011-03-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural and Histone Binding Ability Characterizations of Human PWWP Domains.
Plos One, 6, 2011
2R3A
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BU of 2r3a by Molmil
Methyltransferase domain of human suppressor of variegation 3-9 homolog 2
Descriptor: Histone-lysine N-methyltransferase SUV39H2, S-ADENOSYLMETHIONINE, SERINE, ...
Authors:Lunin, V.V, Wu, H, Zeng, H, Ren, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2007-08-29
Release date:2007-09-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural biology of human H3K9 methyltransferases
Plos One, 5, 2010
3PFS
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BU of 3pfs by Molmil
PWWP Domain of Human Bromodomain and PHD finger-containing protein 3
Descriptor: Bromodomain and PHD finger-containing protein 3, SULFATE ION, ZINC ION
Authors:Lam, R, Zeng, H, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC)
Deposit date:2010-10-29
Release date:2010-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and histone binding ability characterizations of human PWWP domains.
Plos One, 6, 2011
3QJ6
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BU of 3qj6 by Molmil
The crystal structure of PWWP domain of human Hepatoma-derived growth factor 2 in complex with H3K79me3 peptide
Descriptor: H3K79me3, Hepatoma-derived growth factor-related protein 2, SULFATE ION, ...
Authors:Zeng, H, Amaya, M.F, Tempel, W, Walker, J.R, Mackenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC)
Deposit date:2011-01-28
Release date:2011-02-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Histone Binding Ability Characterizations of Human PWWP Domains.
Plos One, 6, 2011
1CA9
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BU of 1ca9 by Molmil
STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A PEPTIDE FROM TNF-R2
Descriptor: PROTEIN (TNF RECEPTOR ASSOCIATED FACTOR 2), PROTEIN (TNF-R2)
Authors:Park, Y.C, Burkitt, V, Villa, A.R, Tong, L, Wu, H.
Deposit date:1999-02-25
Release date:1999-04-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for self-association and receptor recognition of human TRAF2.
Nature, 398, 1999
6MIX
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BU of 6mix by Molmil
Human TRPM2 ion channel in apo state
Descriptor: Transient receptor potential cation channel subfamily M member 2
Authors:Wang, L, Fu, T.M, Xia, S, Wu, H.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures and gating mechanism of human TRPM2.
Science, 362, 2018
6MIZ
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BU of 6miz by Molmil
Human TRPM2 ion channel in an ADPR-bound state
Descriptor: Transient receptor potential cation channel subfamily M member 2
Authors:Wang, L, Fu, T.M, Xia, S, Wu, H.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structures and gating mechanism of human TRPM2.
Science, 362, 2018
6BZE
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BU of 6bze by Molmil
Cryo-EM structure of BCL10 CARD filament
Descriptor: B-cell lymphoma/leukemia 10
Authors:David, L, Li, Y, Ma, J, Garner, E, Zhang, X, Wu, H.
Deposit date:2017-12-23
Release date:2018-02-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Assembly mechanism of the CARMA1-BCL10-MALT1-TRAF6 signalosome.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2O28
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BU of 2o28 by Molmil
Crystal Structure of GNPNAT1
Descriptor: 2-acetamido-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, COENZYME A, Glucosamine 6-phosphate N-acetyltransferase
Authors:Min, J, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-11-29
Release date:2006-12-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Glucosamine-Phosphate N-Acetyltransferase 1
To be Published
2O07
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BU of 2o07 by Molmil
Human spermidine synthase
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, SPERMIDINE, Spermidine synthase
Authors:Min, J, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-11-27
Release date:2006-12-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structure and mechanism of spermidine synthases.
Biochemistry, 46, 2007
6NHW
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Structure of the transmembrane domain of the Death Receptor 5 - Dimer of Trimer
Descriptor: Tumor necrosis factor receptor superfamily member 10B
Authors:Chou, J.J, Pan, L, Fu, Q, Zhao, L, Chen, W, Piai, A, Fu, T, Wu, H.
Deposit date:2018-12-24
Release date:2019-02-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling.
Cell, 176, 2019
2O06
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BU of 2o06 by Molmil
Human spermidine synthase
Descriptor: 1,4-DIAMINOBUTANE, 5'-DEOXY-5'-METHYLTHIOADENOSINE, MAGNESIUM ION, ...
Authors:Min, J, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-11-27
Release date:2006-12-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and mechanism of spermidine synthases.
Biochemistry, 46, 2007
2O8J
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BU of 2o8j by Molmil
Human euchromatic histone methyltransferase 2
Descriptor: Histone-lysine N-methyltransferase, H3 lysine-9 specific 3, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Min, J, Wu, H, Antoshenko, T, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-12-12
Release date:2007-01-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural biology of human H3K9 methyltransferases
Plos One, 5, 2010

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