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PDB: 270 件
8BQN
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BU of 8bqn by Molmil
Structure of empty Coxsackievirus A10 embedded in crystalline ice frozen at -140 degree
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3
著者Shi, H, Wu, C, Zhang, X.
登録日2022-11-21
公開日2023-01-11
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Addressing compressive deformation of proteins embedded in crystalline ice.
Structure, 31, 2023
7V3P
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BU of 7v3p by Molmil
Cryo-EM structure of the IGF1R/insulin complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ...
著者Zhang, J, Liu, C, Zhang, X, Wei, T, Wu, C.
登録日2021-08-11
公開日2022-08-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structure of the IGF1R/insulin complex
To Be Published
8SZG
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BU of 8szg by Molmil
Cryo-EM structure of cinacalcet-bound human calcium-sensing receptor CaSR-Gq complex in lipid nanodiscs
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者He, F, Wu, C, Gao, Y, Skiniotis, G.
登録日2023-05-29
公開日2024-02-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Allosteric modulation and G-protein selectivity of the Ca 2+ -sensing receptor.
Nature, 626, 2024
2VXV
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BU of 2vxv by Molmil
Crystal structure of human IgG ABT-325 Fab Fragment
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GLYCEROL, HUMAN IGG ABT-325
著者Argiriadi, M.A, Xiang, T, Wu, C, Ghayur, T, Borhani, D.W.
登録日2008-07-10
公開日2009-06-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Unusual Water-Mediated Antigenic Recognition of the Proinflammatory Cytokine Interleukin-18.
J.Biol.Chem., 284, 2009
2VXT
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BU of 2vxt by Molmil
Crystal structure of human IL-18 complexed to murine reference antibody 125-2H Fab
分子名称: CHLORIDE ION, INTERLEUKIN-18, MAGNESIUM ION, ...
著者Argiriadi, M.A, Xiang, T, Wu, C, Ghayur, T, Borhani, D.W.
登録日2008-07-10
公開日2009-06-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Unusual Water-Mediated Antigenic Recognition of the Proinflammatory Cytokine Interleukin-18.
J.Biol.Chem., 284, 2009
2VXU
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BU of 2vxu by Molmil
Crystal structure of murine reference antibody 125-2H Fab fragment
分子名称: MURINE IGG 125-2H
著者Argiriadi, M.A, Xiang, T, Wu, C, Ghayur, T, Borhani, D.W.
登録日2008-07-10
公開日2009-06-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Unusual Water-Mediated Antigenic Recognition of the Proinflammatory Cytokine Interleukin-18.
J.Biol.Chem., 284, 2009
8SZH
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BU of 8szh by Molmil
Cryo-EM structure of cinacalcet-bound human calcium-sensing receptor CaSR-Gi complex in lipid nanodiscs
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者He, F, Wu, C, Gao, Y, Skiniotis, G.
登録日2023-05-29
公開日2024-02-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Allosteric modulation and G-protein selectivity of the Ca 2+ -sensing receptor.
Nature, 626, 2024
8SZI
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BU of 8szi by Molmil
Cryo-EM structure of PAM-free human calcium-sensing receptor CaSR-Gi complex in lipid nanodiscs
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者He, F, Wu, C, Gao, Y, Skiniotis, G.
登録日2023-05-29
公開日2024-02-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Allosteric modulation and G-protein selectivity of the Ca 2+ -sensing receptor.
Nature, 626, 2024
6LN1
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BU of 6ln1 by Molmil
A natural inhibitor of DYRK1A for treatment of diabetes mellitus
分子名称: 1,3,5,8-tetrakis(oxidanyl)xanthen-9-one, Dual specificity tyrosine-phosphorylation-regulated kinase 1A
著者Li, H, Chen, L.X, Zheng, M.Z, Zhang, Q.Z, Zhang, C.L, Wu, C.R, Yang, K.Y, Song, Z.R, Wang, Q.Q, Li, C, Zhou, Y.R, Chen, J.C.
登録日2019-12-28
公開日2021-10-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.699 Å)
主引用文献A natural DYRK1A inhibitor as a potential stimulator for beta-cell proliferation in diabetes.
Clin Transl Med, 11, 2021
8SZF
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BU of 8szf by Molmil
Cryo-EM structure of cinacalcet-bound active-state human calcium-sensing receptor CaSR in lipid nanodiscs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者He, F, Wu, C, Gao, Y, Skiniotis, G.
登録日2023-05-29
公開日2024-02-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Allosteric modulation and G-protein selectivity of the Ca 2+ -sensing receptor.
Nature, 626, 2024
5B7C
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BU of 5b7c by Molmil
Crystal structure of octopus S-crystallin Q108F mutant in complex with glutathione
分子名称: GLUTATHIONE, S-crystallin OctvuS4, SULFATE ION
著者Chou, C.-Y, Tan, W.-H, Wu, C.-G.
登録日2016-06-07
公開日2016-08-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure of a Highly Active Cephalopod S-crystallin Mutant: New Molecular Evidence for Evolution from an Active Enzyme into Lens-Refractive Protein.
Sci Rep, 6, 2016
1XPY
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BU of 1xpy by Molmil
Structural Basis for Catalytic Racemization and Substrate Specificity of an N-Acylamino Acid Racemase Homologue from Deinococcus radiodurans
分子名称: MAGNESIUM ION, N-acylamino acid racemase, N~2~-ACETYL-L-GLUTAMINE
著者Wang, W.-C, Chiu, W.-C, Hsu, S.-K, Wu, C.-L, Chen, C.-Y, Liu, J.-S, Hsu, W.-H.
登録日2004-10-10
公開日2004-10-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for catalytic racemization and substrate specificity of an N-acylamino acid racemase homologue from Deinococcus radiodurans
J.Mol.Biol., 342, 2004
1XS2
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BU of 1xs2 by Molmil
Structural Basis for Catalytic Racemization and Substrate Specificity of an N-Acylamino Acid Racemase Homologue from Deinococcus radiodurans
分子名称: MAGNESIUM ION, N-Acylamino Acid Racemase
著者Wang, W.-C, Chiu, W.-C, Hsu, S.-K, Wu, C.-L, Chen, C.-Y, Liu, J.-S, Hsu, W.-H.
登録日2004-10-18
公開日2004-11-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for catalytic racemization and substrate specificity of an N-acylamino acid racemase homologue from Deinococcus radiodurans
J.Mol.Biol., 342, 2004
3R7C
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BU of 3r7c by Molmil
The structure of a hexahestidine-tagged form of augmenter of liver regeneration reveals a novel Cd(2)Cl(4)O(6) cluster that aids in crystal packing
分子名称: CADMIUM ION, CHLORIDE ION, FAD-linked sulfhydryl oxidase ALR, ...
著者Florence, Q.J, Wu, C.-K, Swindell II, J.T, Wang, B.C, Rose, J.P.
登録日2011-03-22
公開日2012-03-28
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of a hexahestidine-tagged form of augmenter of liver regeneration reveals a novel Cd(2)Cl(4)O(6) cluster that aids in crystal packing
To be Published
8IWS
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BU of 8iws by Molmil
hSPCA1 in the CaE2P state
分子名称: BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, Calcium-transporting ATPase type 2C member 1, ...
著者Liu, Z.M, Wu, M.Q, Wu, C.
登録日2023-03-31
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Structure and transport mechanism of the human calcium pump SPCA1.
Cell Res., 33, 2023
8IWT
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BU of 8iwt by Molmil
hSPCA1 in the early E2P state
分子名称: BERYLLIUM TRIFLUORIDE ION, Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION
著者Liu, Z.M, Wu, M.Q, Wu, C.
登録日2023-03-31
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structure and transport mechanism of the human calcium pump SPCA1.
Cell Res., 33, 2023
8IWR
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BU of 8iwr by Molmil
hSPCA1 in the CaE1-ATP state
分子名称: CALCIUM ION, Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION, ...
著者Liu, Z.M, Wu, M.Q, Wu, C.
登録日2023-03-31
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Structure and transport mechanism of the human calcium pump SPCA1.
Cell Res., 33, 2023
8IWU
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BU of 8iwu by Molmil
hSPCA1 in the E2~P state
分子名称: Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION, TETRAFLUOROALUMINATE ION
著者Liu, Z.M, Wu, M.Q, Wu, C.
登録日2023-03-31
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.31 Å)
主引用文献Structure and transport mechanism of the human calcium pump SPCA1.
Cell Res., 33, 2023
8IWW
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BU of 8iww by Molmil
hSPCA1 in the CaE1P-ADP state
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Calcium-transporting ATPase type 2C member 1, ...
著者Liu, Z.M, Wu, M.Q, Wu, C.
登録日2023-03-31
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Structure and transport mechanism of the human calcium pump SPCA1.
Cell Res., 33, 2023
8EW2
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BU of 8ew2 by Molmil
Cryo-EM structure of Aldolase embedded in crystalline ice
分子名称: Fructose-bisphosphate aldolase A
著者Shi, H, Wu, C, Zhang, X.
登録日2022-10-21
公開日2023-01-11
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Addressing compressive deformation of proteins embedded in crystalline ice.
Structure, 31, 2023
8F49
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BU of 8f49 by Molmil
1.8 angstrom structure of apoferritin embedded in crystalline ice
分子名称: Ferritin heavy chain
著者Shi, H, Wu, C, Zhang, X.
登録日2022-11-10
公開日2023-01-11
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (1.8 Å)
主引用文献Addressing compressive deformation of proteins embedded in crystalline ice.
Structure, 31, 2023
8EW0
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BU of 8ew0 by Molmil
Cryo-EM structure of glutamate dehydrogenase frozen at various temperature
分子名称: Glutamate dehydrogenase 1, mitochondrial
著者Shi, H, Wu, C, Zhang, X.
登録日2022-10-21
公開日2023-01-11
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Addressing compressive deformation of proteins embedded in crystalline ice.
Structure, 31, 2023
8F7Y
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BU of 8f7y by Molmil
Structure of Coxsackievirus A10 frozen at -183 degree embedded in crystalline ice
分子名称: Genome polyprotein
著者Shi, H, Wu, C, Zhang, X.
登録日2022-11-21
公開日2023-01-11
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Addressing compressive deformation of proteins embedded in crystalline ice.
Structure, 31, 2023
1R0M
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BU of 1r0m by Molmil
Structure of Deinococcus radiodurans N-acylamino acid racemase at 1.3 : insights into a flexible binding pocket and evolution of enzymatic activity
分子名称: N-acylamino acid racemase
著者Wang, W.-C, Chiu, W.-C, Hsu, S.-K, Wu, C.-L, Chen, C.-Y, Liu, J.-S, Hsu, W.-H.
登録日2003-09-22
公開日2004-09-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural basis for catalytic racemization and substrate specificity of an N-acylamino acid racemase homologue from Deinococcus radiodurans
J.Mol.Biol., 342, 2004
8GUF
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BU of 8guf by Molmil
Crystal structure of cyclic B subunit of type II heat labile enterotoxin
分子名称: Heat-labile enterotoxin IIB, B chain
著者Peng, Y.J, Wu, C.Y, Sue, S.C.
登録日2022-09-12
公開日2023-09-20
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Crystal structure of cyclic B subunit of type II heat labile enterotoxin
To Be Published

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件を2024-06-12に公開中

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