8PCE
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![BU of 8pce by Molmil](/molmil-images/mine/8pce) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 250 ms | Descriptor: | BORATE ION, Beta-lactamase, SULFATE ION | Authors: | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | Deposit date: | 2023-06-11 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Time resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification To Be Published
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2W3Z
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![BU of 2w3z by Molmil](/molmil-images/mine/2w3z) | Structure of a Streptococcus mutans CE4 esterase | Descriptor: | PHOSPHATE ION, PUTATIVE DEACETYLASE, ZINC ION | Authors: | Deng, D.M, Urch, J.E, ten Cate, J.M, Rao, V.A, van Aalten, D.M.F, Crielaard, W. | Deposit date: | 2008-11-17 | Release date: | 2008-12-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Streptococcus Mutans Smu.623C Codes for a Functional, Metal Dependent Polysaccharide Deacetylase that Modulates Interactions with Salivary Agglutinin. J.Bacteriol., 191, 2009
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8PCG
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![BU of 8pcg by Molmil](/molmil-images/mine/8pcg) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 2000 ms | Descriptor: | BORATE ION, Beta-lactamase, SULFATE ION | Authors: | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | Deposit date: | 2023-06-11 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Time resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification To Be Published
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8PCV
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![BU of 8pcv by Molmil](/molmil-images/mine/8pcv) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 10000 ms | Descriptor: | BORATE ION, Beta-lactamase, SULFATE ION, ... | Authors: | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | Deposit date: | 2023-06-11 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Time resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification To Be Published
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8PCS
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![BU of 8pcs by Molmil](/molmil-images/mine/8pcs) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 1250 ms | Descriptor: | BORATE ION, Beta-lactamase, SULFATE ION, ... | Authors: | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | Deposit date: | 2023-06-11 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Time resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification To Be Published
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2EPP
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![BU of 2epp by Molmil](/molmil-images/mine/2epp) | Solution structure of the first C2H2 type zinc finger domain of Zinc finger protein 278 | Descriptor: | POZ-, AT hook-, and zinc finger-containing protein 1, ... | Authors: | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2008-02-12 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the first C2H2 type zinc finger domain of Zinc finger protein 278 To be Published
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2EQY
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![BU of 2eqy by Molmil](/molmil-images/mine/2eqy) | Solution structure of the ARID domain of Jarid1b protein | Descriptor: | Jumonji, AT rich interactive domain 1B | Authors: | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2007-10-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the ARID domain of Jarid1b protein To be Published
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2WFG
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![BU of 2wfg by Molmil](/molmil-images/mine/2wfg) | Structure of the Candida albicans cytosolic leucyl-tRNA synthetase editing domain bound to a benzoxaborole-AMP adduct | Descriptor: | CYTOSOLIC LEUCYL-TRNA SYNTHETASE, [(1S,3S,5R,6R,8R)-6-(6-AMINOPURIN-9-YL)-4'-ETHYLAMINO-3'-FLUORO-SPIRO[2,4,7-TRIOXA-3-BORANUIDABICYCLO[3.3.0]OCTANE-3,7'-8-OXA-7-BORANUIDABICYCLO[4.3.0]NONA-1,3,5-TRIENE]-8-YL]METHYL DIHYDROGEN PHOSPHATE | Authors: | Seiradake, E, Mao, W, Hernandez, V, Baker, S.J, Plattner, J.J, Alley, M.R.K, Cusack, S. | Deposit date: | 2009-04-05 | Release date: | 2009-05-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structures of the Human and Fungal Cytosolic Leucyl-tRNA Synthetase Editing Domains: A Structural Basis for the Rational Design of Antifungal Benzoxaboroles. J.Mol.Biol., 390, 2009
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2E5Q
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![BU of 2e5q by Molmil](/molmil-images/mine/2e5q) | Solution structure of the TUDOR domain of PHD finger protein 19, isoform b [Homo sapiens] | Descriptor: | PHD finger protein 19 | Authors: | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-12-22 | Release date: | 2007-06-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the TUDOR domain of PHD finger protein 19,
isoform b [Homo sapiens] To be Published
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8PCO
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![BU of 8pco by Molmil](/molmil-images/mine/8pco) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 150 ms | Descriptor: | BORATE ION, Beta-lactamase, SULFATE ION, ... | Authors: | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | Deposit date: | 2023-06-11 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Time resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification To Be Published
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2E70
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![BU of 2e70 by Molmil](/molmil-images/mine/2e70) | Solution structure of the fifth KOW motif of human transcription elongation factor SPT5 | Descriptor: | Transcription elongation factor SPT5 | Authors: | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-05 | Release date: | 2007-07-10 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the fifth KOW motif of human transcription elongation factor SPT5 To be Published
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2VCM
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![BU of 2vcm by Molmil](/molmil-images/mine/2vcm) | Isopenicillin N synthase with substrate analogue AsMCOV | Descriptor: | FE (II) ION, ISOPENICILLIN N SYNTHETASE, N^6^-[(1R,2S)-1-({[(1R)-1-carboxy-2-methylpropyl]oxy}carbonyl)-2-sulfanylpropyl]-6-oxo-L-lysine, ... | Authors: | Ge, W, Clifton, I.J, Adlington, R.M, Baldwin, J.E, Rutledge, P.J. | Deposit date: | 2007-09-25 | Release date: | 2008-11-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural Studies on the Reaction of Isopenicillin N Synthase with a Sterically Demanding Depsipeptide Substrate Analogue. Chembiochem, 10, 2009
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2V16
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![BU of 2v16 by Molmil](/molmil-images/mine/2v16) | Crystal Structure of Renin with Inhibitor 3 | Descriptor: | METHYL (3R)-1-[(5S,6S,8R)-5-AMINO-9-BUTYLAMINO-6-HYDROXY-3,3,8-TRIMETHYL-9-OXO-NONANOYL]-3,4-DIHYDRO-2H-QUINOLINE-3-CARBOXYLATE, RENIN | Authors: | Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G. | Deposit date: | 2007-05-22 | Release date: | 2008-07-08 | Last modified: | 2019-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin Chem.Biol., 7, 2000
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3TXO
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![BU of 3txo by Molmil](/molmil-images/mine/3txo) | PKC eta kinase in complex with a naphthyridine | Descriptor: | 2-methyl-N~1~-[3-(pyridin-4-yl)-2,6-naphthyridin-1-yl]propane-1,2-diamine, Protein kinase C eta type | Authors: | Stark, W, Rummel, G, Cowan-Jacob, S.W. | Deposit date: | 2011-09-23 | Release date: | 2011-11-30 | Last modified: | 2011-12-07 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | 2,6-Naphthyridines as potent and selective inhibitors of the novel protein kinase C isozymes. Bioorg.Med.Chem.Lett., 21, 2011
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2ECR
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![BU of 2ecr by Molmil](/molmil-images/mine/2ecr) | Crystal structure of the ligand-free form of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase | Descriptor: | flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase | Authors: | Kim, S.H, Hisano, T, Iwasaki, W, Ebihara, A, Miki, K. | Deposit date: | 2007-02-13 | Release date: | 2008-01-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase from Thermus thermophilus HB8: Structural basis for the flavin affinity Proteins, 70, 2008
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2V0A
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![BU of 2v0a by Molmil](/molmil-images/mine/2v0a) | Atomic resolution crystal structure of Human Superoxide Dismutase | Descriptor: | ACETATE ION, COPPER (II) ION, SULFATE ION, ... | Authors: | Strange, R.W, Antonyuk, S, Yong, C.W, Smith, W, Hasnain, S.S. | Deposit date: | 2007-05-11 | Release date: | 2007-06-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Molecular Dynamics Using Atomic-Resolution Structure Reveal Structural Fluctuations that May Lead to Polymerization of Human Cu-Zn Superoxide Dismutase. Proc.Natl.Acad.Sci.USA, 104, 2007
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2V5Y
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![BU of 2v5y by Molmil](/molmil-images/mine/2v5y) | Crystal structure of the receptor protein tyrosine phosphatase mu ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE MU, SODIUM ION | Authors: | Aricescu, A.R, Siebold, C, Choudhuri, K, Chang, V.T, Lu, W, Davis, S.J, van der Merwe, P.A, Jones, E.Y. | Deposit date: | 2007-07-11 | Release date: | 2007-09-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of a Tyrosine Phosphatase Adhesive Interaction Reveals a Spacer-Clamp Mechanism. Science, 317, 2007
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2V0Z
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![BU of 2v0z by Molmil](/molmil-images/mine/2v0z) | Crystal Structure of Renin with Inhibitor 10 (Aliskiren) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALISKIREN, RENIN | Authors: | Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G. | Deposit date: | 2007-05-21 | Release date: | 2007-07-03 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin Chem.Biol., 7, 2000
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2V8F
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![BU of 2v8f by Molmil](/molmil-images/mine/2v8f) | Mouse Profilin IIa in complex with a double repeat from the FH1 domain of mDia1 | Descriptor: | GLYCEROL, ISOPROPYL ALCOHOL, PROFILIN-2, ... | Authors: | Kursula, P, Kursula, I, Downer, J, Witke, W, Wilmanns, M. | Deposit date: | 2007-08-07 | Release date: | 2007-12-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | High-Resolution Structural Analysis of Mammalian Profilin 2A Complex Formation with Two Physiological Ligands: The Formin Homology 1 Domain of Mdia1 and the Proline-Rich Domain of Vasp. J.Mol.Biol., 375, 2008
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1CSB
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![BU of 1csb by Molmil](/molmil-images/mine/1csb) | |
2ED4
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![BU of 2ed4 by Molmil](/molmil-images/mine/2ed4) | Crystal structure of flavin reductase HpaC complexed with FAD and NAD | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, flavin reductase (HpaC) of 4-hydroxyphenylacetate 3-monooxygenae | Authors: | Kim, S.H, Hisano, T, Iwasaki, W, Ebihara, A, Miki, K. | Deposit date: | 2007-02-14 | Release date: | 2008-01-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase from Thermus thermophilus HB8: Structural basis for the flavin affinity Proteins, 70, 2008
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3U3T
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![BU of 3u3t by Molmil](/molmil-images/mine/3u3t) | The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6) | Descriptor: | Tumor necrosis factor receptor superfamily member 21 | Authors: | Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J. | Deposit date: | 2011-10-06 | Release date: | 2012-05-02 | Last modified: | 2012-07-11 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS Acta Crystallogr.,Sect.D, 68, 2012
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2V13
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![BU of 2v13 by Molmil](/molmil-images/mine/2v13) | Crystal Structure of Renin with Inhibitor 7 | Descriptor: | N-[(2R,4S,5S,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXOOCTYL]-2-(3-METHOXYPROPOXY)BENZAMIDE, RENIN | Authors: | Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G. | Deposit date: | 2007-05-21 | Release date: | 2008-07-08 | Last modified: | 2019-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin Chem.Biol., 7, 2000
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2E2D
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![BU of 2e2d by Molmil](/molmil-images/mine/2e2d) | Flexibility and variability of TIMP binding: X-ray structure of the complex between collagenase-3/MMP-13 and TIMP-2 | Descriptor: | CALCIUM ION, Matrix metallopeptidase 13, Metalloproteinase inhibitor 2, ... | Authors: | Maskos, K, Lang, R, Tschesche, H, Bode, W. | Deposit date: | 2006-11-11 | Release date: | 2007-03-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Flexibility and Variability of TIMP Binding: X-ray Structure of the Complex Between Collagenase-3/MMP-13 and TIMP-2 J.Mol.Biol., 366, 2007
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2C1X
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![BU of 2c1x by Molmil](/molmil-images/mine/2c1x) | Structure and activity of a flavonoid 3-O glucosyltransferase reveals the basis for plant natural product modification | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, UDP-GLUCOSE FLAVONOID 3-O GLYCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | Authors: | Offen, W, Martinez-Fleites, C, Kiat-Lim, E, Yang, M, Davis, B.G, Tarling, C.A, Ford, C.M, Bowles, D.J, Davies, G.J. | Deposit date: | 2005-09-22 | Release date: | 2006-01-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of a Flavonoid Glucosyltransferase Reveals the Basis for Plant Natural Product Modification. Embo J., 25, 2006
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