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PDB: 12895 件

2EQM
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Solution structure of the TUDOR domain of PHD finger protein 20-like 1 [Homo sapiens]
分子名称: PHD finger protein 20-like 1
著者Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-30
公開日2007-10-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the TUDOR domain of PHD finger protein 20-like 1 [Homo sapiens]
To be Published
2EPR
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Solution structure of the secound zinc finger domain of Zinc finger protein 278
分子名称: POZ-, AT hook-, and zinc finger-containing protein 1, ...
著者Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-30
公開日2008-04-01
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the secound zinc finger domain of Zinc finger protein 278
To be Published
5K0X
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Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC2541
分子名称: (7S)-7-amino-N-[(4-fluorophenyl)methyl]-8-oxo-2,9,16,18,21-pentaazabicyclo[15.3.1]henicosa-1(21),17,19-triene-20-carboxamide, CHLORIDE ION, Tyrosine-protein kinase Mer
著者McIver, A.L, Zhang, W, Liu, Q, Jiang, X, Stashko, M.A, Nichols, J, Miley, M.J, Norris-Drouin, J, Machius, M, DeRyckere, D, Wood, E, Graham, D.K, Earp, H.S, Kireev, D, Frye, S.V, Wang, X.
登録日2016-05-17
公開日2017-02-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.231 Å)
主引用文献Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.
ChemMedChem, 12, 2017
2V4E
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A non-cytotoxic DsRed variant for whole-cell labeling
分子名称: RED FLUORESCENT PROTEIN DRFP583
著者Strack, R.L, Strongin, D.E, Bhattacharyya, D, Tao, W, Berman, A, Broxmeyer, H.E, Keenan, R.J, Glick, B.S.
登録日2008-09-20
公開日2008-11-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Noncytotoxic Dsred Variant for Whole-Cell Labeling.
Nat.Methods, 5, 2008
2EQP
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Solution structure of the stn_TNFRSF12A_TNFR domain of Tumor necrosis factor receptor superfamily member 12A precursor
分子名称: Tumor necrosis factor receptor superfamily member 12A
著者Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-30
公開日2008-04-01
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the stn_TNFRSF12A_TNFR domain of Tumor necrosis factor receptor superfamily member 12A precursor
To be Published
1CRK
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MITOCHONDRIAL CREATINE KINASE
分子名称: CREATINE KINASE, PHOSPHATE ION
著者Fritz-Wolf, K, Schnyder, T, Wallimann, T, Kabsch, W.
登録日1996-03-08
公開日1997-07-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of mitochondrial creatine kinase.
Nature, 381, 1996
5K2B
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2.5 angstrom A2a adenosine receptor structure with MR phasing using XFEL data
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, ...
著者Batyuk, A, Galli, L, Ishchenko, A, Han, G.W, Gati, C, Popov, P, Lee, M.-Y, Stauch, B, White, T.A, Barty, A, Aquila, A, Hunter, M.S, Liang, M, Boutet, S, Pu, M, Liu, Z.-J, Nelson, G, James, D, Li, C, Zhao, Y, Spence, J.C.H, Liu, W, Fromme, P, Katritch, V, Weierstall, U, Stevens, R.C, Cherezov, V, GPCR Network (GPCR)
登録日2016-05-18
公開日2016-09-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.
Sci Adv, 2, 2016
1L3P
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CRYSTAL STRUCTURE OF THE FUNCTIONAL DOMAIN OF THE MAJOR GRASS POLLEN ALLERGEN Phl p 5b
分子名称: MAGNESIUM ION, PHOSPHATE ION, POLLEN ALLERGEN Phl p 5b
著者Rajashankar, K.R, Bufe, A, Weber, W, Eschenburg, S, Lindner, B, Betzel, C.
登録日2002-02-28
公開日2003-02-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structure of the functional domain of the major grass-pollen allergen Phlp 5b.
Acta Crystallogr.,Sect.D, 58, 2002
2V79
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Crystal Structure of the N-terminal domain of DnaD from Bacillus Subtilis
分子名称: CHLORIDE ION, DNA REPLICATION PROTEIN DNAD, SODIUM ION
著者Schneider, S, Zhang, W, Soultanas, P, Paoli, M.
登録日2007-07-27
公開日2008-01-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the N-Terminal Oligomerization Domain of Dnad Reveals a Unique Tetramerization Motif and Provides Insights Into Scaffold Formation.
J.Mol.Biol., 376, 2008
2V10
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Crystal Structure of Renin with Inhibitor 9
分子名称: (2R,4S,5S,7S)-5-AMINO-N-BUTYL-4-HYDROXY-7-[4-METHOXY-3-(3-METHOXYPROPOXY)BENZYL]-2,8-DIMETHYLNONANAMIDE, RENIN
著者Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G.
登録日2007-05-21
公開日2007-07-03
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
2VG4
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Rv2361 native
分子名称: UNDECAPRENYL PYROPHOSPHATE SYNTHETASE
著者Naismith, J.H, Wang, W, Dong, C.
登録日2007-11-08
公開日2007-11-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The structural basis of chain length control in Rv1086.
J. Mol. Biol., 381, 2008
2B25
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Human putative tRNA(1-methyladenosine)methyltransferase
分子名称: S-ADENOSYLMETHIONINE, UNKNOWN ATOM OR ION, hypothetical protein
著者Tempel, W, Wu, H, Dong, A, Zeng, H, Loppnau, P, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2005-09-16
公開日2005-09-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Human putative tRNA(1-methyladenosine)methyltransferase
To be Published
5K0U
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CryoEM structure of the full virion of a human rhinovirus C
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Liu, Y, Hill, M.G, Klose, T, Chen, Z, Watters, K.E, Jiang, W, Palmenberg, A.C, Rossmann, M.G.
登録日2016-05-17
公開日2016-07-13
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Atomic structure of a rhinovirus C, a virus species linked to severe childhood asthma.
Proc.Natl.Acad.Sci.USA, 113, 2016
2B2Y
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Tandem chromodomains of human CHD1
分子名称: Chromodomain-helicase-DNA-binding protein 1
著者Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S.
登録日2005-09-19
公開日2005-12-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
5KA4
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Protein Tyrosine Phosphatase 1B T178A mutant, open state
分子名称: Tyrosine-protein phosphatase non-receptor type 1
著者Choy, M.S, Peti, W, Page, R.
登録日2016-06-01
公開日2017-03-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.185 Å)
主引用文献Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol. Cell, 65, 2017
5KAB
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Protein Tyrosine Phosphatase 1B Delta helix 7, P185G mutant in complex with TCS401, open state
分子名称: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Choy, M.S, Machado, L.E.S.F, Peti, W, Page, R.
登録日2016-06-01
公開日2017-03-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.968 Å)
主引用文献Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol. Cell, 65, 2017
2VAU
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Isopenicillin N synthase with substrate analogue ACOMP (unexposed)
分子名称: FE (II) ION, ISOPENICILLIN N SYNTHETASE, N6^-[(1R)-2-[(1S)-1-CARBOXY-2-(METHYLSULFANYL)ETHOXY]-2-OXO-1-(SULFANYLMETHYL)ETHYL]-6-OXO-L-LYSINE
著者Ge, W, Clifton, I.J, Adlington, R.M, Baldwin, J.E, Rutledge, P.J.
登録日2007-09-04
公開日2008-07-29
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Isopenicillin N Synthase Mediates Thiolate Oxidation to Sulfenate in a Depsipeptide Substrate Analogue: Implications for Oxygen Binding and a Link to Nitrile Hydratase?
J.Am.Chem.Soc., 130, 2008
2V0G
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LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A tRNA(leu) transcript with 5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1- BENZOXABOROLE (AN2690) forming an adduct to the ribose of adenosine- 76 in the enzyme editing site.
分子名称: AMINOACYL-TRNA SYNTHETASE, LEUCINE, MERCURY (II) ION, ...
著者Rock, F, Mao, W, Yaremchuk, A, Tukalo, M, Crepin, T, Zhou, H, Zhang, Y, Hernandez, V, Akama, T, Baker, S, Plattner, J, Shapiro, L, Martinis, S.A, Benkovic, S.J, Cusack, S, Alley, M.R.K.
登録日2007-05-14
公開日2007-07-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site.
Science, 316, 2007
1D5S
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CRYSTAL STRUCTURE OF CLEAVED ANTITRYPSIN POLYMER
分子名称: P1-ARG ANTITRYPSIN
著者Dunstone, M.A, Dai, W, Whisstock, J.C, Rossjohn, J, Pike, R.N, Feil, S.C, Le Bonneic, B.F, Parker, M.W, Bottomley, S.P.
登録日1999-10-11
公開日2000-04-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Cleaved antitrypsin polymers at atomic resolution.
Protein Sci., 9, 2000
2B2U
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Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and dimethylarginine 2
分子名称: Chromodomain-helicase-DNA-binding protein 1, Histone H3
著者Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S.
登録日2005-09-19
公開日2005-12-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
3RSH
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Structure of 3-ketoacyl-(acyl-carrier-protein)reductase (FabG) from Vibrio cholerae O1 complexed with NADP+ (space group P62)
分子名称: 1,2-ETHANEDIOL, 3-oxoacyl-[acyl-carrier protein] reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Hou, J, Chruszcz, M, Cooper, D.R, Grabowski, M, Zheng, H, Osinski, T, Shumilin, I, Anderson, W, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2011-05-02
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.
J.Bacteriol., 198, 2015
2B2V
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Crystal structure analysis of human CHD1 chromodomains 1 and 2 bound to histone H3 resi 1-15 MeK4
分子名称: Chromodomain-helicase-DNA-binding protein 1, Histone H3
著者Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S.
登録日2005-09-19
公開日2005-12-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
1CJB
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MALARIAL PURINE PHOSPHORIBOSYLTRANSFERASE
分子名称: (1S)-1(9-DEAZAHYPOXANTHIN-9YL)1,4-DIDEOXY-1,4-IMINO-D-RIBITOL-5-PHOSPHATE, MAGNESIUM ION, PROTEIN (HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE), ...
著者Shi, W, Li, C.M, Tyler, P.C, Furneaux, R.H, Cahill, S.M, Girvin, M.E, Grubmeyer, C, Schramm, V.L, Almo, S.C.
登録日1999-04-08
公開日1999-08-18
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor.
Biochemistry, 38, 1999
1CM5
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CRYSTAL STRUCTURE OF C418A,C419A MUTANT OF PFL FROM E.COLI
分子名称: CARBONATE ION, PROTEIN (PYRUVATE FORMATE-LYASE), SODIUM ION
著者Becker, A, Fritz-Wolf, K, Kabsch, W, Knappe, J, Schultz, S, Wagner, A.F.V.
登録日1999-05-14
公開日1999-12-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and mechanism of the glycyl radical enzyme pyruvate formate-lyase.
Nat.Struct.Biol., 6, 1999
2WO7
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Isopenicillin N synthase with substrate analogue L,L,D-ACd2Ab (unexposed)
分子名称: DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VINYLGLYCINE, FE (II) ION, ISOPENICILLIN N SYNTHASE
著者Ge, W, Clifton, I.J, Adlington, R.M, Baldwin, J.E, Rutledge, P.J.
登録日2009-07-22
公開日2010-07-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystallographic Studies on the Binding of Selectively Deuterated Lld- and Lll-Substrate Epimers by Isopenicillin N Synthase.
Biochem.Biophys.Res.Commun., 398, 2010

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