6PKJ
 
 | | MicroED structure of proteinase K from an uncoated, single lamella at 2.17A resolution (#2) | | 分子名称: | Proteinase K | | 著者 | Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T. | | 登録日 | 2019-06-29 | | 公開日 | 2019-09-04 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.176 Å) | | 主引用文献 | Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED.
Structure, 27, 2019
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6PKO
 | | MicroED structure of proteinase K from a platinum coated, unpolished, single lamella at 2.07A resolution (#12) | | 分子名称: | Proteinase K | | 著者 | Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T. | | 登録日 | 2019-06-29 | | 公開日 | 2019-09-04 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.07 Å) | | 主引用文献 | Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED.
Structure, 27, 2019
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3DR0
 | | Structure of reduced cytochrome c6 from Synechococcus sp. PCC 7002 | | 分子名称: | Cytochrome c6, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | 著者 | Bialek, W, Krzywda, S, Jaskolski, M, Szczepaniak, A. | | 登録日 | 2008-07-10 | | 公開日 | 2009-07-14 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | | 主引用文献 | Atomic-resolution structure of reduced cyanobacterial cytochrome c6 with an unusual sequence insertion
Febs J., 276, 2009
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6VIZ
 | | BRD4_Bromodomain1 complex with pyrrolopyridone compound 27 | | 分子名称: | 4-[2-(2,6-dimethylphenoxy)-5-(ethylsulfonyl)phenyl]-N-ethyl-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide, Bromodomain-containing protein 4 | | 著者 | Longenecker, K.L, Park, C.H, Qiu, W. | | 登録日 | 2020-01-14 | | 公開日 | 2020-05-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.391 Å) | | 主引用文献 | Discovery ofN-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide (ABBV-744), a BET Bromodomain Inhibitor with Selectivity for the Second Bromodomain.
J.Med.Chem., 63, 2020
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4FNV
 | | Crystal Structure of Heparinase III | | 分子名称: | Heparinase III protein, heparitin sulfate lyase | | 著者 | Dong, W, Ye, S. | | 登録日 | 2012-06-20 | | 公開日 | 2012-11-28 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis of heparan sulfate-specific degradation by heparinase III.
Protein Cell, 3, 2012
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6PKR
 | | MicroED structure of proteinase K from a platinum-coated, polished, single lamella at 1.79A resolution (#13) | | 分子名称: | Proteinase K | | 著者 | Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T. | | 登録日 | 2019-06-29 | | 公開日 | 2019-09-04 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.79 Å) | | 主引用文献 | Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED.
Structure, 27, 2019
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6PKK
 | | MicroED structure of proteinase K from an uncoated, single lamella at 2.18A resolution (#5) | | 分子名称: | Proteinase K | | 著者 | Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T. | | 登録日 | 2019-06-29 | | 公開日 | 2019-09-04 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.176 Å) | | 主引用文献 | Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED.
Structure, 27, 2019
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6PKP
 | | MicroED structure of proteinase K from a platinum-coated, polished, single lamella at 1.91A resolution (#10) | | 分子名称: | Proteinase K | | 著者 | Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T. | | 登録日 | 2019-06-29 | | 公開日 | 2019-09-04 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.91 Å) | | 主引用文献 | Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED.
Structure, 27, 2019
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6VRO
 | | The structure of the PP2A B56 subunit AIM1 complex | | 分子名称: | Beta/gamma crystallin domain-containing protein 1, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | | 著者 | Wang, X, Page, R, Peti, W. | | 登録日 | 2020-02-08 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment.
Elife, 9, 2020
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6VPS
 | | Cryo-EM structure of the amyloid core of Drosophila Orb2 isolated from head | | 分子名称: | Translational regulator orb2 | | 著者 | Hervas, R, Rau, M.J, Park, Y, Zhang, W, Murzin, A.G, Fitzpatrick, J.A.J, Scheres, S.H.W, Si, K. | | 登録日 | 2020-02-04 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila
Science, 367, 2020
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6PQ0
 | | LCP-embedded Proteinase K treated with MPD | | 分子名称: | CALCIUM ION, Proteinase K | | 著者 | Bu, G, Zhu, L, Jing, L, Shi, D, Gonen, T, Liu, W, Nannenga, B.L. | | 登録日 | 2019-07-08 | | 公開日 | 2020-08-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2 Å) | | 主引用文献 | Structure Determination from Lipidic Cubic Phase Embedded Microcrystals by MicroED.
Structure, 28, 2020
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6VQV
 | | Type I-F CRISPR-Csy complex with its inhibitor AcrF9 | | 分子名称: | AcrF9, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ... | | 著者 | Zhang, K, Li, S, Pintilie, G, Zhu, Y, Huang, Z, Chiu, W. | | 登録日 | 2020-02-06 | | 公開日 | 2020-03-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | | 主引用文献 | Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6POM
 | | Cryo-EM structure of the full-length Bacillus subtilis glyQS T-box riboswitch in complex with tRNA-Gly | | 分子名称: | T-box GlyQS leader (155-MER), tRNAGly (75-MER) | | 著者 | Li, S, Su, Z, Zhang, J, Chiu, W. | | 登録日 | 2019-07-04 | | 公開日 | 2019-11-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Structural basis of amino acid surveillance by higher-order tRNA-mRNA interactions.
Nat.Struct.Mol.Biol., 26, 2019
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6W2D
 | | Structures of Capsid and Capsid-Associated Tegument Complex inside the Epstein-Barr Virus | | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | | 著者 | Liu, W, Cui, Y.X, Wang, C.Y, Li, Z.H, Gong, D.Y, Dai, X.H, Bi, G.Q, Sun, R, Zhou, Z.H. | | 登録日 | 2020-03-05 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus.
Nat Microbiol, 5, 2020
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6PQ4
 | | LCP-embedded Proteinase K treated with lipase | | 分子名称: | CALCIUM ION, NITRATE ION, Proteinase K | | 著者 | Bu, G, Zhu, L, Jing, L, Shi, D, Gonen, T, Liu, W, Nannenga, B.L. | | 登録日 | 2019-07-08 | | 公開日 | 2020-08-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2 Å) | | 主引用文献 | Structure Determination from Lipidic Cubic Phase Embedded Microcrystals by MicroED.
Structure, 28, 2020
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6VIW
 | | BRD4_Bromodomain1 complex with pyrrolopyridone compound 18 | | 分子名称: | 4-[2-(2,4-difluorophenoxy)-5-(methylsulfonyl)phenyl]-N-ethyl-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide, Bromodomain-containing protein 4 | | 著者 | Longenecker, K.L, Park, C.H, Qiu, W. | | 登録日 | 2020-01-14 | | 公開日 | 2020-05-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.429 Å) | | 主引用文献 | Discovery ofN-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide (ABBV-744), a BET Bromodomain Inhibitor with Selectivity for the Second Bromodomain.
J.Med.Chem., 63, 2020
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4H2J
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6PS3
 | | XFEL beta2 AR structure by ligand exchange from Timolol to Carvedilol. | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-1-(8H-CARBAZOL-4-YLOXY)-3-[2-(2-METHOXYPHENOXY)ETHYLAMINO]PROPAN-2-OL, CHOLESTEROL, ... | | 著者 | Ishchenko, A, Stauch, B, Han, G.W, Batyuk, A, Shiriaeva, A, Li, C, Zatsepin, N.A, Weierstall, U, Liu, W, Nango, E, Nakane, T, Tanaka, R, Tono, K, Joti, Y, Iwata, S, Moraes, I, Gati, C, Cherezov, C. | | 登録日 | 2019-07-12 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Toward G protein-coupled receptor structure-based drug design using X-ray lasers.
Iucrj, 6, 2019
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5GRK
 | | Crystal structure of Uracil DNA glycosylase -Xanthine complex from Bradyrhizobium diazoefficiens | | 分子名称: | Blr0248 protein, XANTHINE | | 著者 | Patil, V.V, Ullas, V.C, Ahn, W, Varshney, U, Woo, E. | | 登録日 | 2016-08-11 | | 公開日 | 2017-05-03 | | 最終更新日 | 2017-06-14 | | 実験手法 | X-RAY DIFFRACTION (2.804 Å) | | 主引用文献 | Uracil DNA glycosylase (UDG) activities in Bradyrhizobium diazoefficiens: characterization of a new class of UDG with broad substrate specificity
Nucleic Acids Res., 45, 2017
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6W8T
 | | Crystal structure of metacaspase 4 from Arabidopsis (microcrystals treated with calcium) | | 分子名称: | Metacaspase-4, SULFATE ION | | 著者 | Zhu, P, Yu, X.H, Wang, C, Zhang, Q, Liu, W, McSweeney, S, Shanklin, J, Lam, E, Liu, Q. | | 登録日 | 2020-03-21 | | 公開日 | 2020-05-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for Ca2+-dependent activation of a plant metacaspase.
Nat Commun, 11, 2020
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6PS6
 | | XFEL beta2 AR structure by ligand exchange from Timolol to Timolol. | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol, CHOLESTEROL, ... | | 著者 | Ishchenko, A, Stauch, B, Han, G.W, Batyuk, A, Shiriaeva, A, Li, C, Zatsepin, N.A, Weierstall, U, Liu, W, Nango, E, Nakane, T, Tanaka, R, Tono, K, Joti, Y, Iwata, S, Moraes, I, Gati, C, Cherezov, C. | | 登録日 | 2019-07-12 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Toward G protein-coupled receptor structure-based drug design using X-ray lasers.
Iucrj, 6, 2019
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6WBK
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4H4C
 | | IspH in complex with (E)-4-fluoro-3-methylbut-2-enyl diphosphate | | 分子名称: | (2E)-4-fluoro-3-methylbut-2-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER | | 著者 | Span, I, Eisenreich, W, Jauch, J, Bacher, A, Groll, M. | | 登録日 | 2012-09-17 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of Fluoro, Amino, and Thiol Inhibitors Bound to the [Fe(4) S(4) ] Protein IspH.
Angew.Chem.Int.Ed.Engl., 52, 2013
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6VJV
 | | Crystal structure of the Prochlorococcus phage (myovirus P-SSM2) ferredoxin at 1.6 Angstroms | | 分子名称: | ACETATE ION, FE2/S2 (INORGANIC) CLUSTER, Ferredoxin, ... | | 著者 | Olmos Jr, J.L, Campbell, I.J, Miller, M.D, Xu, W, Kahanda, D, Atkinson, J.T, Sparks, N, Bennett, G.N, Silberg, J.J, Phillips Jr, G.N. | | 登録日 | 2020-01-17 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Prochlorococcusphage ferredoxin: structural characterization and electron transfer to cyanobacterial sulfite reductases.
J.Biol.Chem., 295, 2020
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1DAD
 | | DETHIOBIOTIN SYNTHETASE COMPLEXED WITH ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DETHIOBIOTIN SYNTHETASE | | 著者 | Huang, W, Jia, J, Schneider, G, Lindqvist, Y. | | 登録日 | 1995-05-08 | | 公開日 | 1996-06-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate.
Biochemistry, 34, 1995
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