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PDB: 12380 件

6XV1
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Human Sirt6 13-308 in complex with ADP-ribose and the activator MDL-801
分子名称: 5-[[3,5-bis(chloranyl)phenyl]sulfonylamino]-2-[(5-bromanyl-4-fluoranyl-2-methyl-phenyl)sulfamoyl]benzoic acid, NAD-dependent protein deacetylase sirtuin-6, SULFATE ION, ...
著者You, W, Steegborn, C.
登録日2020-01-21
公開日2020-10-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Binding site for activator MDL-801 on SIRT6.
Nat.Chem.Biol., 17, 2021
6XQB
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SARS-CoV-2 RdRp/RNA complex
分子名称: MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ...
著者Liu, B, Shi, W, Yang, Y.
登録日2020-07-09
公開日2020-07-29
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of SARS-CoV-2 RdRp/RNA complex at 3.4 Angstroms resolution
To Be Published
6XUY
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Human Sirt6 13-308 in complex with ADP-ribose
分子名称: NAD-dependent protein deacetylase sirtuin-6, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者You, W, Steegborn, C.
登録日2020-01-21
公開日2020-10-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Binding site for activator MDL-801 on SIRT6.
Nat.Chem.Biol., 17, 2021
2QK9
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Human RNase H catalytic domain mutant D210N in complex with 18-mer RNA/DNA hybrid
分子名称: 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*T)-3', 5'-R(*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3', CITRATE ANION, ...
著者Nowotny, M, Gaidamakov, S.A, Ghirlando, R, Cerritelli, S.M, Crouch, R.J, Yang, W.
登録日2007-07-10
公開日2007-11-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription
Mol.Cell, 28, 2007
2QQI
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Crystal Structure of the b1b2 Domains from Human Neuropilin-1
分子名称: GLYCEROL, Neuropilin-1
著者Appleton, B.A, Desmarais, W, Wiesmann, C.
登録日2007-07-26
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Embo J., 26, 2007
2QT1
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Human nicotinamide riboside kinase 1 in complex with nicotinamide riboside
分子名称: Nicotinamide riboside, Nicotinamide riboside kinase 1, PHOSPHATE ION, ...
著者Rabeh, W.M, Tempel, W, Nedyalkova, L, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Brenner, C, Park, H, Structural Genomics Consortium (SGC)
登録日2007-07-31
公開日2007-08-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+).
Plos Biol., 5, 2007
2QNC
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Crystal structure of T4 Endonuclease VII N62D mutant in complex with a DNA Holliday junction
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*DAP*DGP*DGP*DCP*DCP*DTP*DAP*DGP*DCP*DGP*DTP*DCP*DCP*DGP*DGP*DAP*DAP*DTP*DTP*DCP*DTP*DTP*DCP*DG)-3'), DNA (5'-D(*DCP*DAP*DCP*DAP*DTP*DCP*DGP*DAP*DTP*DGP*DGP*DAP*DGP*DCP*DCP*DGP*DCP*DTP*DAP*DGP*DGP*DCP*DCP*DT)-3'), ...
著者Biertumpfel, C, Yang, W, Suck, D.
登録日2007-07-18
公開日2008-01-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of T4 endonuclease VII resolving a Holliday junction.
Nature, 449, 2007
2R1Q
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Crystal Structure of Iodinated Human Saposin D in Space Group C2221
分子名称: Proactivator polypeptide
著者Maier, T, Rossman, M, Saenger, W.
登録日2007-08-23
公開日2008-04-29
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2R2O
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Crystal structure of the effector domain of human Plexin B1
分子名称: Plexin-B1, UNKNOWN ATOM OR ION
著者Tong, Y, Tempel, W, Shen, L, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2007-08-27
公開日2007-09-04
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain.
J.Biol.Chem., 282, 2007
2QXJ
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Crystal Structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone and Copper
分子名称: COPPER (II) ION, Kallikrein-7, N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-[(2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]-L-prolinamide
著者Debela, M, Hess, P, Magdolen, V, Schechter, N.M, Bode, W, Goettig, P.
登録日2007-08-11
公開日2008-01-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QKB
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Human RNase H catalytic domain mutant D210N in complex with 20-mer RNA/DNA hybrid
分子名称: 1,2-ETHANEDIOL, 5'-D(*DGP*DGP*DAP*DAP*DTP*DCP*DAP*DGP*DGP*DTP*DGP*DTP*DCP*DGP*DCP*DAP*DCP*DTP*DCP*DT)-3', 5'-R(*GP*GP*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3'), ...
著者Nowotny, M, Gaidamakov, S.A, Ghirlando, R, Cerritelli, S.M, Crouch, R.J, Yang, W.
登録日2007-07-10
公開日2007-11-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription
Mol.Cell, 28, 2007
2QKK
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Human RNase H catalytic domain mutant D210N in complex with 14-mer RNA/DNA hybrid
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*G)-3', ...
著者Nowotny, M, Gaidamakov, S.A, Ghirlando, R, Cerritelli, S.M, Crouch, R.J, Yang, W.
登録日2007-07-11
公開日2007-11-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription
Mol.Cell, 28, 2007
2QSZ
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Human nicotinamide riboside kinase 1 in complex with nicotinamide mononucleotide
分子名称: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, CHLORIDE ION, Nicotinamide riboside kinase 1, ...
著者Rabeh, W.M, Tempel, W, Nedyalkova, L, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Brenner, C, Park, H, Structural Genomics Consortium (SGC)
登録日2007-07-31
公開日2007-08-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+).
Plos Biol., 5, 2007
2QXI
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High resolution structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone
分子名称: Kallikrein-7, N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-[(2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]-L-prolinamide
著者Debela, M, Hess, P, Magdolen, V, Schechter, N.M, Bode, W, Goettig, P.
登録日2007-08-11
公開日2008-01-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QTA
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E. coli Pyruvate dehydrogenase E1 component E401K mutant with thiamin diphosphate
分子名称: MAGNESIUM ION, Pyruvate dehydrogenase E1 component, THIAMINE DIPHOSPHATE
著者Furey, W, Arjunan, P, Chandrasekhar, K.
登録日2007-08-01
公開日2007-08-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A Dynamic Loop at the Active Center of the Escherichia coli Pyruvate Dehydrogenase Complex E1 Component Modulates Substrate Utilization and Chemical Communication with the E2 Component
J.Biol.Chem., 282, 2007
2QNF
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Crystal structure of T4 Endonuclease VII H43N mutant in complex with heteroduplex DNA containing base mismatches
分子名称: DNA (5'-D(*DCP*DAP*DCP*DAP*DTP*DCP*DGP*DAP*DTP*DGP*DGP*DAP*DGP*DCP*DCP*DG)-3'), DNA (5'-D(*DCP*DAP*DCP*DAP*DTP*DCP*DGP*DAP*DTP*DGP*DGP*DAP*DGP*DCP*DGP*DC)-3'), DNA (5'-D(*DCP*DGP*DGP*DCP*DTP*DCP*DCP*DAP*DTP*DCP*DGP*DAP*DTP*DGP*DTP*DG)-3'), ...
著者Biertumpfel, C, Yang, W, Suck, D.
登録日2007-07-18
公開日2008-01-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of T4 endonuclease VII resolving a Holliday junction.
Nature, 449, 2007
2QNU
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Crystal structure of PA0076 from Pseudomonas aeruginosa PAO1 at 2.05 A resolution
分子名称: ACETATE ION, TRIETHYLENE GLYCOL, Uncharacterized protein PA0076
著者Filippova, E.V, Chruszcz, M, Skarina, T, Kagan, O, Cymborowski, M, Savchenko, A, Edwards, A.M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2007-07-19
公開日2007-07-31
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of Pa0076 from Pseudomonas aeruginosa PAO1 at 2.05 A resolution.
To be Published
2QP2
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Structure of a MACPF/perforin-like protein
分子名称: CALCIUM ION, Unknown protein
著者Rosado, C.J, Buckle, A.M, Law, R.H.P, Butcher, R.E, Kan, W.T, Bird, C.H, Ung, K, Browne, K.A, Baran, K, Bashtannyk-Puhalovich, T.A, Faux, N.G, Wong, W, Porter, C.J, Pike, R.N, Ellisdon, A.M, Pearce, M.C, Bottomley, S.P, Emsley, J, Smith, A.I, Rossjohn, J, Hartland, E.L, Voskoboinik, I, Trapani, J.A, Bird, P.I, Dunstone, M.A, Whisstock, J.C.
登録日2007-07-22
公開日2007-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A common fold mediates vertebrate defense and bacterial attack
Science, 317, 2007
2QT0
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Human nicotinamide riboside kinase 1 in complex with nicotinamide riboside and an ATP analogue
分子名称: MAGNESIUM ION, Nicotinamide riboside, Nicotinamide riboside kinase 1, ...
著者Rabeh, W.M, Tempel, W, Nedyalkova, L, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Brenner, C, Park, H, Structural Genomics Consortium (SGC)
登録日2007-07-31
公開日2007-08-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+).
Plos Biol., 5, 2007
2QQ8
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Crystal structure of the putative RabGAP domain of human TBC1 domain family member 14
分子名称: TBC1 domain family member 14, UNKNOWN ATOM OR ION
著者Tong, Y, Tempel, W, Dimov, S, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2007-07-26
公開日2007-08-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the putative RabGAP domain of human TBC1 domain family member 14.
To be Published
2QT5
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Crystal Structure of GRIP1 PDZ12 in Complex with the Fras1 Peptide
分子名称: (ASN)(ASN)(LEU)(GLN)(ASP)(GLY)(THR)(GLU)(VAL), 1,2-ETHANEDIOL, ACETIC ACID, ...
著者Long, J, Wei, Z, Feng, W, Zhao, Y, Zhang, M.
登録日2007-08-01
公開日2008-06-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Supramodular nature of GRIP1 revealed by the structure of its PDZ12 tandem in complex with the carboxyl tail of Fras1.
J.Mol.Biol., 375, 2008
2R13
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Crystal structure of human mitoNEET reveals a novel [2Fe-2S] cluster coordination
分子名称: CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, Zinc finger CDGSH domain-containing protein 1
著者Hou, X, Liu, R, Ross, S, Smart, E.J, Zhu, H, Gong, W.
登録日2007-08-22
公開日2007-09-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystallographic studies of human MitoNEET
J.Biol.Chem., 282, 2007
2R2D
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Structure of a quorum-quenching lactonase (AiiB) from Agrobacterium tumefaciens
分子名称: GLYCEROL, PHOSPHATE ION, ZINC ION, ...
著者Liu, D, Thomas, P.W, Momb, J, Hoang, Q, Petsko, G.A, Ringe, D, Fast, W.
登録日2007-08-24
公開日2007-10-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure and specificity of a quorum-quenching lactonase (AiiB) from Agrobacterium tumefaciens.
Biochemistry, 46, 2007
2R53
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Crystal structure analysis of Bone Morphogenetic Protein-6 variant B2 (B2-BMP-6)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Bone morphogenetic protein 6
著者Mueller, T.D, Sebald, W.
登録日2007-09-03
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand.
Febs J., 275, 2007
2R9H
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Crystal Structure of Q207C Mutant of CLC-ec1 in complex with Fab
分子名称: CHLORIDE ION, Fab fragment, H(+)/Cl(-) exchange transporter clcA
著者Nguitragool, W, Miller, C.
登録日2007-09-12
公開日2007-11-20
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of Q207C Mutant of CLC-ec1 in complex with Fab
To be Published

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