5FKL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fkl by Molmil](/molmil-images/mine/5fkl) | TetR(D) H100A mutant in complex with anhydrotetracycline and magnesium | Descriptor: | 5A,6-ANHYDROTETRACYCLINE, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Werten, S, Schneider, J, Palm, G.J, Hinrichs, W. | Deposit date: | 2015-10-17 | Release date: | 2016-04-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Modular Organisation of Inducer Recognition and Allostery in the Tetracycline Repressor FEBS J., 283, 2016
|
|
2WET
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wet by Molmil](/molmil-images/mine/2wet) | Crystal structure of tryptophan 5-halogenase (PyrH) complex with FAD (tryptophan) | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... | Authors: | De Laurentis, W, Zhu, X, Naismith, J.H. | Deposit date: | 2009-04-01 | Release date: | 2009-04-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Insights in the Regioselectivity in the Enzymatic Chlorination of Tryptophan. J.Mol.Biol., 391, 2009
|
|
2VSH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2vsh by Molmil](/molmil-images/mine/2vsh) | Synthesis of CDP-activated ribitol for teichoic acid precursors in Streptococcus pneumoniae | Descriptor: | 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Baur, S, Marles-Wright, J, Buckenmaier, S, Lewis, R.J, Vollmer, W. | Deposit date: | 2008-04-23 | Release date: | 2008-12-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Synthesis of Cdp-Activated Ribitol for Teichoic Acid Precursors in Streptococcus Pneumoniae. J.Bacteriol., 191, 2009
|
|
4GGC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ggc by Molmil](/molmil-images/mine/4ggc) | |
2WHV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2whv by Molmil](/molmil-images/mine/2whv) | CRYSTAL STRUCTURE OF MOUSE CADHERIN-23 EC1-2 (ALL CATION BINDING SITES OCCUPIED BY CALCIUM) | Descriptor: | CADHERIN-23, CALCIUM ION, CHLORIDE ION, ... | Authors: | Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. | Deposit date: | 2009-05-07 | Release date: | 2010-04-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Structural Determinants of Cadherin-23 Function in Hearing and Deafness. Neuron, 66, 2010
|
|
2WJH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wjh by Molmil](/molmil-images/mine/2wjh) | Structure and function of the FeoB G-domain from Methanococcus jannaschii | Descriptor: | CITRATE ANION, FERROUS IRON TRANSPORT PROTEIN B HOMOLOG, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Koester, S, Wehner, M, Herrmann, C, Kuehlbrandt, W, Yildiz, O. | Deposit date: | 2009-05-26 | Release date: | 2009-07-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and Function of the Feob G-Domain from Methanococcus Jannaschii J.Mol.Biol., 392, 2009
|
|
5BJP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5bjp by Molmil](/molmil-images/mine/5bjp) | Crystal structure of the Corn RNA aptamer in complex with DFHO, iridium hexammine soak | Descriptor: | (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, DIMETHYL SULFOXIDE, IRIDIUM ION, ... | Authors: | Warner, K.D, Song, W, Filonov, G.S, Jaffrey, S.R, Ferre-D'Amare, A.R. | Deposit date: | 2016-08-21 | Release date: | 2017-09-27 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | A homodimer interface without base pairs in an RNA mimic of red fluorescent protein. Nat. Chem. Biol., 13, 2017
|
|
5FHD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fhd by Molmil](/molmil-images/mine/5fhd) | Structure of Bacteroides sp Pif1 complexed with tailed dsDNA resulting in ssDNA bound complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*CP*CP*GP*GP*GP*GP*CP*CP*GP*CP*GP*C)-3'), MAGNESIUM ION, ... | Authors: | Zhou, X, Ren, W, Bharath, S.R, Song, H. | Deposit date: | 2015-12-22 | Release date: | 2016-03-30 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1 Cell Rep, 14, 2016
|
|
5FRA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fra by Molmil](/molmil-images/mine/5fra) | CBM40_CPF0721-6'SL | Descriptor: | ACETATE ION, N-acetyl-alpha-neuraminic acid, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose, ... | Authors: | Ribeiro, J.P, Pau, W, Pifferi, C, Renaudet, O, Varrot, A, Mahal, L.K, Imberty, A. | Deposit date: | 2015-12-16 | Release date: | 2016-07-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Characterization of a High-Affinity Sialic Acid-Specific Cbm40 from Clostridium Perfringens and Engineering of a Divalent Form. Biochem.J., 473, 2016
|
|
5TO2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5to2 by Molmil](/molmil-images/mine/5to2) | |
5FTB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ftb by Molmil](/molmil-images/mine/5ftb) | Crystal structure of Pif1 helicase from Bacteroides in complex with AMPPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, POTASSIUM ION, ... | Authors: | Chen, W.-F, Dai, Y.-X, Duan, X.-L, Liu, N.-N, Shi, W, Li, M, Dou, S.-X, Li, N, Dong, Y.-H, Rety, S, Xi, X.-G. | Deposit date: | 2016-01-12 | Release date: | 2016-02-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Crystal Structures of the Bspif1 Helicase Reveal that a Major Movement of the 2B SH3 Domain is Required for DNA Unwinding Nucleic Acids Res., 44, 2016
|
|
5FAI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fai by Molmil](/molmil-images/mine/5fai) | EMG1 N1-Specific Pseudouridine Methyltransferase | Descriptor: | CITRIC ACID, Ribosomal RNA small subunit methyltransferase NEP1, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | DONG, A, ZENG, H, LI, Y, TEMPEL, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, WU, H, Structural Genomics Consortium (SGC) | Deposit date: | 2015-12-11 | Release date: | 2016-01-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | EMG1 N1-Specific Pseudouridine Methyltransferase to be published
|
|
5TGP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5tgp by Molmil](/molmil-images/mine/5tgp) | DNA 8mer containing two 2SeT modifications | Descriptor: | DNA/RNA (5'-R(*G)-D(P*(2ST))-R(P*G)-D(P*(2ST))-R(P*AP*CP*AP*C)-3') | Authors: | Zhang, W, Huang, Z. | Deposit date: | 2016-09-28 | Release date: | 2017-10-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | DNA 8mer containing two 2SeT modifications To Be Published
|
|
2WJI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wji by Molmil](/molmil-images/mine/2wji) | Structure and function of the FeoB G-domain from Methanococcus jannaschii | Descriptor: | FERROUS IRON TRANSPORT PROTEIN B HOMOLOG, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Koester, S, Wehner, M, Herrmann, C, Kuehlbrandt, W, Yildiz, O. | Deposit date: | 2009-05-26 | Release date: | 2009-07-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.903 Å) | Cite: | Structure and Function of the Feob G-Domain from Methanococcus Jannaschii J.Mol.Biol., 392, 2009
|
|
5B18
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5b18 by Molmil](/molmil-images/mine/5b18) | Crystal Structure of a Darunavir Resistant HIV-1 Protease | Descriptor: | ACETATE ION, CHLORIDE ION, Protease | Authors: | Suzuki, K, Ode, H, Nakashima, M, Sugiura, W, Watanabe, N, Suzuki, A, Iwatani, Y. | Deposit date: | 2015-11-30 | Release date: | 2016-04-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Unique Flap Conformation in an HIV-1 Protease with High-Level Darunavir Resistance Front Microbiol, 7, 2016
|
|
2WQB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wqb by Molmil](/molmil-images/mine/2wqb) | Structure of the Tie2 kinase domain in complex with a thiazolopyrimidine inhibitor | Descriptor: | 2-[3-(CYCLOHEXYLMETHYL)-5-PHENYL-IMIDAZOL-4-YL]-[1,3]THIAZOLO[4,5-E]PYRIMIDIN-7-AMINE, ANGIOPOIETIN-1 RECEPTOR | Authors: | Brassington, C, Breed, J, Buttar, D, Fitzek, M, Forder, C, Hassall, L, Hayter, B.R, Jones, C.D, Luke, R.W.A, McCall, E, McCoull, W, Norman, R, Paterson, D, McMiken, H, Rowsell, S, Tucker, J.A. | Deposit date: | 2009-08-18 | Release date: | 2009-11-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Novel Thienopyrimidine and Thiazolopyrimidine Kinase Inhibitors with Activity Against Tie-2 in Vitro and in Vivo. Bioorg.Med.Chem.Lett., 19, 2009
|
|
5B24
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5b24 by Molmil](/molmil-images/mine/5b24) | The crystal structure of the nucleosome containing cyclobutane pyrimidine dimer | Descriptor: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Horikoshi, N, Tachiwana, H, Kagawa, W, Osakabe, A, Kurumizaka, H. | Deposit date: | 2015-12-31 | Release date: | 2016-03-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Crystal structure of the nucleosome containing ultraviolet light-induced cyclobutane pyrimidine dimer Biochem.Biophys.Res.Commun., 471, 2016
|
|
2VFW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2vfw by Molmil](/molmil-images/mine/2vfw) | Rv1086 native | Descriptor: | SHORT-CHAIN Z-ISOPRENYL DIPHOSPHATE SYNTHETASE, SULFATE ION | Authors: | Naismith, J.H, Wang, W, Dong, C. | Deposit date: | 2007-11-05 | Release date: | 2007-11-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The structural basis of chain length control in Rv1086. J. Mol. Biol., 381, 2008
|
|
5HZ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hz0 by Molmil](/molmil-images/mine/5hz0) | Plant peptide hormone receptor RGFR1 in complex with RGF2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ASP-PTR-TRP-LYS-PRO-ARG-HIS-HIS-PRO-HYP-ARG-ASN-ASN, ... | Authors: | Song, W, Han, Z, Chai, J. | Deposit date: | 2016-02-02 | Release date: | 2017-04-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Plant Receptor To Be Published
|
|
5HZQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hzq by Molmil](/molmil-images/mine/5hzq) | Crystal structure of cellular retinoic acid binding protein 2 (CRABP2)-aryl fluorosulfate covalent conjugate | Descriptor: | 4'-[(3,6,9,12-tetraoxapentadec-14-yn-1-yl)oxy][1,1'-biphenyl]-4-yl sulfurofluoridate, Cellular retinoic acid-binding protein 2, GLYCEROL | Authors: | Chen, W, Mortenson, D.E, Wilson, I.A, Kelly, J.W. | Deposit date: | 2016-02-02 | Release date: | 2016-06-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue. J.Am.Chem.Soc., 138, 2016
|
|
5H71
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h71 by Molmil](/molmil-images/mine/5h71) | Structure of alginate-binding protein AlgQ2 in complex with an alginate trisaccharide | Descriptor: | 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid, AlgQ2, CALCIUM ION, ... | Authors: | Uenishi, K, Kaneko, A, Maruyama, Y, Mikami, B, Murata, K, Hashimoto, W. | Deposit date: | 2016-11-15 | Release date: | 2017-08-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.549 Å) | Cite: | A solute-binding protein in the closed conformation induces ATP hydrolysis in a bacterial ATP-binding cassette transporter involved in the import of alginate J. Biol. Chem., 292, 2017
|
|
5HLT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hlt by Molmil](/molmil-images/mine/5hlt) | Crystal structure of pyrene- and phenanthrene-modified DNA in complex with the BpuJ1 endonuclease binding domain | Descriptor: | DNA (5'-D(*GP*YPY*TP*AP*CP*CP*CP*GP*TP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*AP*CP*GP*GP*GP*TP*AP*YPY*C)-3'), Restriction endonuclease R.BpuJI | Authors: | Probst, M, Aeschimann, W, Chau, T.-T.-H, Langenegger, S.M, Stocker, A, Haener, R. | Deposit date: | 2016-01-15 | Release date: | 2016-08-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.672 Å) | Cite: | Structural insight into DNA-assembled oligochromophores: crystallographic analysis of pyrene- and phenanthrene-modified DNA in complex with BpuJI endonuclease. Nucleic Acids Res., 44, 2016
|
|
2VVU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2vvu by Molmil](/molmil-images/mine/2vvu) | Aminopyrrolidine Factor Xa inhibitor | Descriptor: | 5-chloro-N-[(3R)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)pyrrolidin-3-yl]thiophene-2-carboxamide, ACTIVATED FACTOR XA HEAVY CHAIN, CALCIUM ION, ... | Authors: | Groebke-Zbinden, K, Banner, D.W, Benz, J.M, Blasco, F, Decoret, G, Himber, J, Kuhn, B, Panday, N, Ricklin, F, Risch, P, Schlatter, D, Stahl, M, Unger, R, Haap, W. | Deposit date: | 2008-06-11 | Release date: | 2009-07-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Design of Novel Aminopyrrolidine Factor Xa Inhibitors from a Screening Hit. Eur.J.Med.Chem., 44, 2009
|
|
2WGU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wgu by Molmil](/molmil-images/mine/2wgu) | Structure of human adenovirus serotype 37 fibre head in complex with a sialic acid derivative, O-Methyl 5-N- methoxycarbonyl -3,5-dideoxy- D-glycero-a-D-galacto-2-nonulopyranosylonic acid | Descriptor: | 3,5-dideoxy-5-[(methoxycarbonyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid, FIBER PROTEIN, ZINC ION | Authors: | Johansson, S, Nilsson, E, Qian, W, Guilligay, D, Crepin, T, Cusack, S, Arnberg, N, Elofsson, M. | Deposit date: | 2009-04-27 | Release date: | 2009-11-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Design, Synthesis, and Evaluation of N-Acyl Modified Sialic Acids as Inhibitors of Adenoviruses Causing Epidemic Keratoconjunctivitis. J.Med.Chem., 52, 2009
|
|
5HI0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hi0 by Molmil](/molmil-images/mine/5hi0) | The Substrate Binding Mode and Chemical Basis of a Reaction Specificity Switch in Oxalate Decarboxylase | Descriptor: | COBALT (II) ION, OXALATE ION, Oxalate decarboxylase OxdC, ... | Authors: | Zhu, W, Easthon, L.M, Reinhardt, L.A, Tu, C, Cohen, S.E, Silverman, D.N, Allen, K.N, Richards, N.G.J. | Deposit date: | 2016-01-11 | Release date: | 2016-04-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.602 Å) | Cite: | Substrate Binding Mode and Molecular Basis of a Specificity Switch in Oxalate Decarboxylase. Biochemistry, 55, 2016
|
|