3CIF
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![BU of 3cif by Molmil](/molmil-images/mine/3cif) | Crystal Structure of C153S mutant glyceraldehyde 3-phosphate dehydrogenase from Cryptosporidium parvum | Descriptor: | GLYCERALDEHYDE-3-PHOSPHATE, GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase, ... | Authors: | Cook, W.J, Senkovich, O, Chattopadhyay, D. | Deposit date: | 2008-03-11 | Release date: | 2009-03-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | An unexpected phosphate binding site in Glyceraldehyde 3-Phosphate Dehydrogenase: Crystal structures of apo, holo and ternary complex of Cryptosporidium parvum enzyme BMC STRUCT.BIOL., 9, 2009
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3CQF
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![BU of 3cqf by Molmil](/molmil-images/mine/3cqf) | Crystal structure of anthrolysin O (ALO) | Descriptor: | Thiol-activated cytolysin | Authors: | Bourdeau, R.W, Malito, E, Tang, W.J. | Deposit date: | 2008-04-02 | Release date: | 2009-03-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Cellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted by Bacillus anthracis J.Biol.Chem., 284, 2009
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3CWW
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![BU of 3cww by Molmil](/molmil-images/mine/3cww) | Crystal Structure of IDE-bradykinin complex | Descriptor: | 1,4-DIETHYLENE DIOXIDE, ACETATE ION, Insulin-degrading enzyme, ... | Authors: | Malito, E, Tang, W.J. | Deposit date: | 2008-04-23 | Release date: | 2008-11-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Molecular Bases for the Recognition of Short Peptide Substrates and Cysteine-Directed Modifications of Human Insulin-Degrading Enzyme Biochemistry, 47, 2008
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3CJJ
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![BU of 3cjj by Molmil](/molmil-images/mine/3cjj) | Crystal structure of human rage ligand-binding domain | Descriptor: | ACETATE ION, Advanced glycosylation end product-specific receptor, ZINC ION | Authors: | Koch, M, Dattilo, B.M, Schiefner, A, Diez, J, Chazin, W.J, Fritz, G. | Deposit date: | 2008-03-13 | Release date: | 2009-03-24 | Last modified: | 2011-12-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis for ligand recognition and activation of RAGE. Structure, 18, 2010
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2AMI
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![BU of 2ami by Molmil](/molmil-images/mine/2ami) | Solution Structure Of The Calcium-loaded N-Terminal Sensor Domain Of Centrin | Descriptor: | Caltractin | Authors: | Hu, H.T, Fagan, P.A, Bunick, C.G, Sheehan, J.H, Chazin, W.J. | Deposit date: | 2005-08-09 | Release date: | 2005-08-23 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of the N-terminal calcium sensor domain of centrin reveals the biochemical basis for domain-specific function. J.Biol.Chem., 281, 2006
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2AW0
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7JJM
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![BU of 7jjm by Molmil](/molmil-images/mine/7jjm) | Crystal structure of Importin alpha 2 in complex with LSD1 NLS | Descriptor: | CHLORIDE ION, Importin subunit alpha-1, Lysine-specific histone demethylase 1A | Authors: | Tu, W.J, McGuaig, R, Tan, H.Y.A, Hardy, C, Seddiki, N, Ali, S, Dahlstrom, J.E, Bean, E.G, Dunn, J, Forwood, J.K, Tsimbalyuk, S, Smith, K.M, Yip, D, Malik, L, Prasana, T, Milburn, P, Rao, S. | Deposit date: | 2020-07-27 | Release date: | 2020-08-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch. Front Immunol, 11, 2020
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2BAY
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![BU of 2bay by Molmil](/molmil-images/mine/2bay) | Crystal structure of the Prp19 U-box dimer | Descriptor: | Pre-mRNA splicing factor PRP19 | Authors: | Vander Kooi, C.W, Ohi, M.D, Rosenberg, J.A, Oldham, M.L, Newcomer, M.E, Gould, K.L, Chazin, W.J. | Deposit date: | 2005-10-15 | Release date: | 2006-01-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The Prp19 U-box Crystal Structure Suggests a Common Dimeric Architecture for a Class of Oligomeric E3 Ubiquitin Ligases. Biochemistry, 45, 2006
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2BCT
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2B0Y
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![BU of 2b0y by Molmil](/molmil-images/mine/2b0y) | Solution Structure of a peptide mimetic of the fourth cytoplasmic loop of the G-protein coupled CB1 cannabinoid receptor | Descriptor: | Cannabinoid receptor 1 | Authors: | Grace, C.R, Cowsik, S.M, Shim, J.Y, Welsh, W.J, Howlett, A.C. | Deposit date: | 2005-09-15 | Release date: | 2006-08-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Unique helical conformation of the fourth cytoplasmic loop of the CB1 cannabinoid receptor in a negatively charged environment. J.Struct.Biol., 159, 2007
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2CYG
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![BU of 2cyg by Molmil](/molmil-images/mine/2cyg) | Crystal structure at 1.45- resolution of the major allergen endo-beta-1,3-glucanase of banana as a molecular basis for the latex-fruit syndrome | Descriptor: | beta-1, 3-glucananse | Authors: | Receveur-Brechot, V, Czjzek, M, Barre, A, Roussel, A, Peumans, W.J, Van Damme, E.J.M, Rouge, P. | Deposit date: | 2005-07-07 | Release date: | 2005-11-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure at 1.45-A resolution of the major allergen endo-beta-1,3-glucanase of banana as a molecular basis for the latex-fruit syndrome Proteins, 63, 2006
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2F4M
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![BU of 2f4m by Molmil](/molmil-images/mine/2f4m) | The Mouse PNGase-HR23 Complex Reveals a Complete Remodulation of the Protein-Protein Interface Compared to its Yeast Orthologs | Descriptor: | CHLORIDE ION, UV excision repair protein RAD23 homolog B, ZINC ION, ... | Authors: | Zhao, G, Zhou, X, Wang, L, Kisker, C, Lennarz, W.J, Schindelin, H. | Deposit date: | 2005-11-23 | Release date: | 2006-03-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways. J.Biol.Chem., 281, 2006
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2D82
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![BU of 2d82 by Molmil](/molmil-images/mine/2d82) | Target Structure-Based Discovery of Small Molecules that Block Human p53 and CREB Binding Protein (CBP) Association | Descriptor: | 9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE, CREB-binding protein | Authors: | Sachchidanand, Resnick-Silverman, L, Yan, S, Mujtaba, S, Liu, W.J, Zeng, L, Manfredi, J.J, Zhou, M.M. | Deposit date: | 2005-12-01 | Release date: | 2006-04-04 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Target structure-based discovery of small molecules that block human p53 and CREB binding protein association Chem.Biol., 13, 2006
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3GAE
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![BU of 3gae by Molmil](/molmil-images/mine/3gae) | Crystal Structure of PUL | Descriptor: | CHLORIDE ION, GLYCEROL, Protein DOA1 | Authors: | Zhao, G, Schindelin, H, Lennarz, W.J. | Deposit date: | 2009-02-17 | Release date: | 2009-12-15 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | An Armadillo motif in Ufd3 interacts with Cdc48 and is involved in ubiquitin homeostasis and protein degradation Proc.Natl.Acad.Sci.USA, 106, 2009
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2HOA
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![BU of 2hoa by Molmil](/molmil-images/mine/2hoa) | STRUCTURE DETERMINATION OF THE ANTP(C39->S) HOMEODOMAIN FROM NUCLEAR MAGNETIC RESONANCE DATA IN SOLUTION USING A NOVEL STRATEGY FOR THE STRUCTURE CALCULATION WITH THE PROGRAMS DIANA, CALIBA, HABAS AND GLOMSA | Descriptor: | ANTENNAPEDIA PROTEIN | Authors: | Guntert, P, Qian, Y.-Q, Otting, G, Muller, M, Gehring, W.J, Wuthrich, K. | Deposit date: | 1992-04-04 | Release date: | 1993-10-31 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure determination of the Antp (C39----S) homeodomain from nuclear magnetic resonance data in solution using a novel strategy for the structure calculation with the programs DIANA, CALIBA, HABAS and GLOMSA. J.Mol.Biol., 217, 1991
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2F4O
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![BU of 2f4o by Molmil](/molmil-images/mine/2f4o) | The Mouse PNGase-HR23 Complex Reveals a Complete Remodulation of the Protein-Protein Interface Compared to its Yeast Orthologs | Descriptor: | CHLORIDE ION, PHQ-VAL-ALA-ASP-CF0, XP-C repair complementing complex 58 kDa protein, ... | Authors: | Zhao, G, Zhou, X, Wang, L, Kisker, C, Lennarz, W.J, Schindelin, H. | Deposit date: | 2005-11-23 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways. J.Biol.Chem., 281, 2006
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4ZF7
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![BU of 4zf7 by Molmil](/molmil-images/mine/4zf7) | Crystal structure of ferret interleukin-2 | Descriptor: | DI(HYDROXYETHYL)ETHER, Interleukin 2, PENTAETHYLENE GLYCOL, ... | Authors: | Ren, B, Newman, J, McKinstry, W.J, Adams, T.E. | Deposit date: | 2015-04-21 | Release date: | 2015-11-04 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.893 Å) | Cite: | Structural and functional characterisation of ferret interleukin-2. Dev.Comp.Immunol., 55, 2015
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4OU0
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4Z8I
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![BU of 4z8i by Molmil](/molmil-images/mine/4z8i) | Crystal structure of Branchiostoma belcheri tsingtauense peptidoglycan recognition protein 3 | Descriptor: | ZINC ION, peptidoglycan recognition protein 3 | Authors: | Wang, W.J, Cheng, W, Jiang, Y.L, Luo, M, Cao, D.D, Chi, C.B, Yang, H.B, Chen, Y, Zhou, C.Z. | Deposit date: | 2015-04-09 | Release date: | 2015-10-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.701 Å) | Cite: | Activity Augmentation of Amphioxus Peptidoglycan Recognition Protein BbtPGRP3 via Fusion with a Chitin Binding Domain Plos One, 10, 2015
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2TSS
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![BU of 2tss by Molmil](/molmil-images/mine/2tss) | TOXIC SHOCK SYNDROME TOXIN-1 FROM STAPHYLOCOCCUS AUREUS: ORTHORHOMBICC222(1) CRYSTAL FORM | Descriptor: | TOXIC SHOCK SYNDROME TOXIN-1 | Authors: | Prasad, G.S, Radhakrishnan, R, Mitchell, D.T, Earhart, C.A, Dinges, M.M, Cook, W.J, Schlivert, P.M, Ohlendorf, D.H. | Deposit date: | 1996-12-04 | Release date: | 1997-12-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity. Protein Sci., 6, 1997
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2SCP
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4QIA
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![BU of 4qia by Molmil](/molmil-images/mine/4qia) | Crystal structure of human insulin degrading enzyme (ide) in complex with inhibitor N-benzyl-N-(carboxymethyl)glycyl-L-histidine | Descriptor: | Insulin-degrading enzyme, N-benzyl-N-(carboxymethyl)glycyl-L-histidine, ZINC ION | Authors: | Guo, Q, Deprez-Poulain, R, Deprez, B, Tang, W.J. | Deposit date: | 2014-05-30 | Release date: | 2015-05-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.202 Å) | Cite: | Structure-activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme. Eur.J.Med.Chem., 90, 2015
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2UCZ
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2UYZ
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![BU of 2uyz by Molmil](/molmil-images/mine/2uyz) | Non-covalent complex between Ubc9 and SUMO1 | Descriptor: | SMALL UBIQUITIN-RELATED MODIFIER 1, SODIUM ION, SUMO-CONJUGATING ENZYME UBC9 | Authors: | Knipscheer, P, van Dijk, W.J, Olsen, J.V, Mann, M, Sixma, T.K. | Deposit date: | 2007-04-21 | Release date: | 2007-06-12 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation. EMBO J., 26, 2007
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5C2V
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![BU of 5c2v by Molmil](/molmil-images/mine/5c2v) | Kuenenia stuttgartiensis Hydrazine Synthase | Descriptor: | CALCIUM ION, CHLORIDE ION, HEME C, ... | Authors: | Dietl, A, Ferousi, C, Maalcke, W.J, Menzel, A, de Vries, S, Keltjens, J.T, Jetten, M.S.M, Kartal, B, Barends, T.R.M. | Deposit date: | 2015-06-16 | Release date: | 2015-10-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The inner workings of the hydrazine synthase multiprotein complex. Nature, 527, 2015
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