2BAY

Crystal structure of the Prp19 U-box dimer

Summary for 2BAY

Entry DOI	10.2210/pdb2bay/pdb
Descriptor	Pre-mRNA splicing factor PRP19 (2 entities in total)
Functional Keywords	prp19, u-box, ubiquitin ligase, e3 ligase, ligase
Biological source	Saccharomyces cerevisiae (baker's yeast)
Cellular location	Nucleus: P32523
Total number of polymer chains	6
Total formula weight	40366.28
Authors	Vander Kooi, C.W.,Ohi, M.D.,Rosenberg, J.A.,Oldham, M.L.,Newcomer, M.E.,Gould, K.L.,Chazin, W.J. (deposition date: 2005-10-15, release date: 2006-01-10, Last modification date: 2024-02-14)
Primary citation	Vander Kooi, C.W.,Ohi, M.D.,Rosenberg, J.A.,Oldham, M.L.,Newcomer, M.E.,Gould, K.L.,Chazin, W.J. The Prp19 U-box Crystal Structure Suggests a Common Dimeric Architecture for a Class of Oligomeric E3 Ubiquitin Ligases. Biochemistry, 45:121-130, 2006 Cited by PubMed: 16388587 DOI: 10.1021/bi051787e PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation