6N8U
 
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2LNQ
 | | 40-residue D23N beta amyloid fibril | | 分子名称: | P3(40) | | 著者 | Qiang, W, Yau, W, Luo, Y, Mattson, M.P, Tycko, R. | | 登録日 | 2012-01-03 | | 公開日 | 2012-02-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Antiparallel beta-sheet architecture in Iowa-mutant beta-amyloid fibrils.
Proc.Natl.Acad.Sci.USA, 109, 2012
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6N7T
 | | Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form III) | | 分子名称: | DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ... | | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | | 登録日 | 2018-11-28 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structures and operating principles of the replisome.
Science, 363, 2019
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3SYY
 | | Crystal Structure of an alkaline exonuclease (LHK-Exo) from Laribacter hongkongensis | | 分子名称: | Exonuclease, MAGNESIUM ION | | 著者 | Yang, W, Chen, W.Y, Wang, H, Zhang, Q, Zhou, W, Bartlam, M, Watt, R.M, Rao, Z. | | 登録日 | 2011-07-18 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis.
Nucleic Acids Res., 39, 2011
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3SZ4
 | | Crystal Structure of LHK-Exo in complex with dAMP | | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Exonuclease, MAGNESIUM ION | | 著者 | Yang, W, Chen, W.Y, Wang, H, Zhang, Q, Zhou, W, Bartlam, M, Watt, R.M, Rao, Z. | | 登録日 | 2011-07-18 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis.
Nucleic Acids Res., 39, 2011
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4DPO
 | | Crystal structure of a conserved protein MM_1583 from Methanosarcina mazei Go1 | | 分子名称: | Conserved protein | | 著者 | Agarwal, R, Chamala, S, Evans, R, Gizzi, A, Hillerich, B, Kar, A, LaFleur, J, Foti, R, Siedel, R, Zencheck, W, Villigas, G, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2012-02-13 | | 公開日 | 2012-02-29 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | | 主引用文献 | Crystal structure of a conserved protein MM_1583 from Methanosarcina mazei Go1
To be Published
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8QAV
 | | Medicago truncatula HISN5 (IGPD) in complex with MN and IG2 | | 分子名称: | (2S,3S)-2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl dihydrogen phosphate, Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION | | 著者 | Witek, W, Ruszkowski, M. | | 登録日 | 2023-08-23 | | 公開日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (2.23 Å) | | 主引用文献 | Targeting imidazole-glycerol phosphate dehydratase in plants: novel approach for structural and functional studies, and inhibitor blueprinting.
Front Plant Sci, 15, 2024
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8QAY
 | | Medicago truncatula HISN5 (IGPD) in complex with MN, FMT, ACT, CIT, EDO, SO4 | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CITRIC ACID, ... | | 著者 | Witek, W, Ruszkowski, M. | | 登録日 | 2023-08-23 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Targeting imidazole-glycerol phosphate dehydratase in plants: novel approach for structural and functional studies, and inhibitor blueprinting.
Front Plant Sci, 15, 2024
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4DQX
 | | Crystal structure of a short chain dehydrogenase from Rhizobium etli CFN 42 | | 分子名称: | Probable oxidoreductase protein | | 著者 | Agarwal, R, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, LaFleur, J, Siedel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2012-02-16 | | 公開日 | 2012-02-29 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of a short chain dehydrogenase from Rhizobium etli CFN 42
To be Published
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8QAW
 | | Medicago truncatula HISN5 (IGPD) in complex with MN, IMD, EDO, FMT, GOL and TRS | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | | 著者 | Witek, W, Ruszkowski, M. | | 登録日 | 2023-08-23 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Targeting imidazole-glycerol phosphate dehydratase in plants: novel approach for structural and functional studies, and inhibitor blueprinting.
Front Plant Sci, 15, 2024
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3SX0
 | | Crystal structure of Dot1l in complex with a brominated SAH analog | | 分子名称: | (2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}sulfanyl)butanoic acid (non-preferred name), Histone-lysine N-methyltransferase, H3 lysine-79 specific, ... | | 著者 | Yu, W, Tempel, W, Smil, D, Schapira, M, Li, Y, Vedadi, M, Nguyen, K.T, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Brown, P.J, Structural Genomics Consortium (SGC) | | 登録日 | 2011-07-14 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Bromo-deaza-SAH: a potent and selective DOT1L inhibitor.
Bioorg. Med. Chem., 21, 2013
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6N7S
 | | Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form II) | | 分子名称: | DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ... | | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | | 登録日 | 2018-11-28 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structures and operating principles of the replisome.
Science, 363, 2019
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6Y08
 | | Mouse thymidylate synthase cocrystallized with dUMP and soaked in sulfamethoxazole | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Sulfamethoxazole, Thymidylate synthase | | 著者 | Maj, P, Jarmula, A, Wilk, P, Weiss, M.S, Rode, W. | | 登録日 | 2020-02-06 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.297 Å) | | 主引用文献 | Mouse thymidylate synthase cocrystallized with dUMP and soaked in sulfamethoxazole
To Be Published
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6N7N
 | | Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form I) | | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA primase/helicase, MAGNESIUM ION, ... | | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | | 登録日 | 2018-11-27 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structures and operating principles of the replisome.
Science, 363, 2019
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6N7V
 | | Structure of bacteriophage T7 gp4 (helicase-primase, E343Q mutant) in complex with ssDNA, dTTP, AC dinucleotide, and CTP (from multiple lead complexes) | | 分子名称: | DNA (93-MER), DNA primase/helicase, MAGNESIUM ION, ... | | 著者 | Gao, Y, Fox, T, Val, N, Yang, W. | | 登録日 | 2018-11-28 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structures and operating principles of the replisome.
Science, 363, 2019
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6YAR
 | | Crystal structure of a Selenium-derivatized complex of the bacterial cellulose secretion regulators BcsR and BcsQ, crystallized in the presence of AppCp | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Bacterial cellulose secretion regulator BcsQ, Bacterial cellulose secretion regulator BcsR, ... | | 著者 | Caleechurn, M, Abidi, W, Zouhir, S, Roche, S, Krasteva, P.V. | | 登録日 | 2020-03-12 | | 公開日 | 2021-02-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Architecture and regulation of an enterobacterial cellulose secretion system.
Sci Adv, 7, 2021
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6YAY
 | | Crystal structure of a Selenium-derivatized complex of the bacterial cellulose secretion regulators BcsR and BcsQ, crystallized in the presence of ADP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Bacterial cellulose secretion regulator BcsQ, Bacterial cellulose secretion regulator BcsR, ... | | 著者 | Abidi, W, Caleechurn, M, Zouhir, S, Roche, S, Krasteva, P.V. | | 登録日 | 2020-03-14 | | 公開日 | 2021-02-24 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Architecture and regulation of an enterobacterial cellulose secretion system.
Sci Adv, 7, 2021
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6N9W
 | | Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS2) | | 分子名称: | DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ... | | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | | 登録日 | 2018-12-04 | | 公開日 | 2019-03-06 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structures and operating principles of the replisome.
Science, 363, 2019
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6YB3
 | | Crystal structure of a native BcsRQ complex purified and crystallized in the absence of nucleotide | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Bacterial cellulose secretion regulator BcsQ, Bacterial cellulose secretion regulator BcsR, ... | | 著者 | Caleechurn, M, Abidi, W, Zouhir, S, Roche, S, Krasteva, P.V. | | 登録日 | 2020-03-15 | | 公開日 | 2021-02-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Architecture and regulation of an enterobacterial cellulose secretion system.
Sci Adv, 7, 2021
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6YB5
 | | Orthorhombic crystal structure of a native BcsRQ complex crystallized in the presence of ADP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Bacterial cellulose secretion regulator BcsQ, Bacterial cellulose secretion regulator BcsR, ... | | 著者 | Caleechurn, M, Abidi, W, Zouhir, S, Roche, S, Krasteva, P.V. | | 登録日 | 2020-03-15 | | 公開日 | 2021-02-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Architecture and regulation of an enterobacterial cellulose secretion system.
Sci Adv, 7, 2021
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6YBB
 | | Crystal structure of a native BcsE (217-523) - BcsR-BcsQ (R156E mutant) complex with c-di-GMP and ATP bound | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ADENOSINE-5'-TRIPHOSPHATE, Bacterial cellulose secretion regulator BcsE, ... | | 著者 | Abidi, W, Zouhir, S, Roche, S, Krasteva, P.V. | | 登録日 | 2020-03-16 | | 公開日 | 2021-02-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Architecture and regulation of an enterobacterial cellulose secretion system.
Sci Adv, 7, 2021
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6YBU
 | | Crystal structure of a native BcsE (349-523) RQ complex with c-di-GMP and ATP bound | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ADENOSINE-5'-TRIPHOSPHATE, Bacterial cellulose secretion regulator BcsE, ... | | 著者 | Abidi, W, Zouhir, S, Roche, S, Krasteva, P.V. | | 登録日 | 2020-03-17 | | 公開日 | 2021-02-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Architecture and regulation of an enterobacterial cellulose secretion system.
Sci Adv, 7, 2021
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6NEY
 | | Crystal structure of TcBDF5, a bromodomain containing protein from Trypanosoma cruzi | | 分子名称: | Uncharacterized protein | | 著者 | Loppnau, P, Dong, A, Tempel, W, Lin, Y.H, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Vedadi, M, Harding, R.J, Structural Genomics Consortium (SGC) | | 登録日 | 2018-12-18 | | 公開日 | 2019-03-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Crystal structure of TcBDF5, a bromodomain containing protein from Trypanosoma cruzi
To Be Published
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6NEZ
 | | Trypanosoma brucei - BDF5, Tb427tmp.01.5000 A, solved with PF-CBP1 | | 分子名称: | 5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-2-[2-(4-propoxyphenyl)ethyl]-1H-benzimidazole, UNKNOWN ATOM OR ION, Uncharacterized protein | | 著者 | Lin, Y.H, Dong, A, Tempel, W, McAuley, J, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Vedadi, M, Harding, R.J, Structural Genomics Consortium (SGC) | | 登録日 | 2018-12-18 | | 公開日 | 2019-01-23 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Trypanosoma brucei - BDF5, Tb427tmp.01.5000 A, solved with PF-CBP1
to be published
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6YIZ
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