4P8U
 
 | | The crystal structures of YKL-39 in the absence of chitooligosaccharides was solved to resolutions of 2.4 angstrom | | 分子名称: | Chitinase-3-like protein 2, DI(HYDROXYETHYL)ETHER, SULFATE ION | | 著者 | Suginta, W, Ranok, A, Robinson, R.C, Wongsantichon, J. | | 登録日 | 2014-04-01 | | 公開日 | 2014-10-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and Thermodynamic Insights into Chitooligosaccharide Binding to Human Cartilage Chitinase 3-like Protein 2 (CHI3L2 or YKL-39).
J.Biol.Chem., 290, 2015
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3JA1
 | | Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Li, W, Liu, Z, Koripella, R.K, Langlois, R, Sanyal, S, Frank, J. | | 登録日 | 2015-03-30 | | 公開日 | 2015-07-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.
Sci Adv, 1, 2015
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3JB7
 | | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus | | 分子名称: | CPV RNA-dependent RNA polymerase, CYTIDINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Zhang, X, Ding, K, Yu, X.K, Chang, W, Sun, J.C, Zhou, Z.H. | | 登録日 | 2015-08-03 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus.
Nature, 527, 2015
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4PMN
 | | Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein Rv2525c in complex with MES (monoclinic crystal form I) | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, SULFATE ION, ... | | 著者 | Bellinzoni, M, Haouz, A, Shepard, W, Alzari, P.M. | | 登録日 | 2014-05-22 | | 公開日 | 2014-10-08 | | 最終更新日 | 2014-12-10 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c.
J.Struct.Biol., 188, 2014
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8WST
 | | Cryo-EM structure of Melanin-Concentrating Hormone Receptor 2 with MCH | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha-1, ... | | 著者 | Zhao, L, He, Q, Yuan, Q, Gu, Y, Shan, H, Hu, W, Wu, K, Xu, H.E, Zhang, Y, Wu, C. | | 登録日 | 2023-10-17 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Mechanisms of ligand recognition and activation of melanin-concentrating hormone receptors.
Cell Discov, 10, 2024
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3JVK
 | | Crystal structure of bromodomain 1 of mouse Brd4 in complex with histone H3-K(ac)14 | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, histone H3.3 peptide | | 著者 | Vollmuth, F, Blankenfeldt, W, Geyer, M. | | 登録日 | 2009-09-17 | | 公開日 | 2009-10-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution
J.Biol.Chem., 284, 2009
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8VRN
 | | Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus PPTQ | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(4-methylphenyl)-2-phenylquinazolin-4(3H)-one, ... | | 著者 | Chojnacka, W, Teng, J, Kim, J.J, Jensen, A.A, Hibbs, R.E. | | 登録日 | 2024-01-22 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | | 主引用文献 | Structural insights into GABA A receptor potentiation by Quaalude.
Nat Commun, 15, 2024
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8WSS
 | | Cryo-EM structure of Melanin-Concentrating Hormone Receptor 1 with MCH | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Zhao, L, He, Q, Yuan, Q, Gu, Y, Shan, H, Hu, W, Wu, K, Xu, H.E, Zhang, Y, Wu, C. | | 登録日 | 2023-10-17 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | | 主引用文献 | Mechanisms of ligand recognition and activation of melanin-concentrating hormone receptors.
Cell Discov, 10, 2024
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8VQY
 | | Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus methaqualone | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-methyl-3-(2-methylphenyl)quinazolin-4(3H)-one, GAMMA-AMINO-BUTANOIC ACID, ... | | 著者 | Chojnacka, W, Teng, J, Kim, J.J, Jensen, A.A, Hibbs, R.E. | | 登録日 | 2024-01-19 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | | 主引用文献 | Structural insights into GABA A receptor potentiation by Quaalude.
Nat Commun, 15, 2024
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4R3I
 | | The crystal structure of an RNA complex | | 分子名称: | RNA (5'-R(*GP*GP*(6MZ)P*CP*U)-3'), UNKNOWN ATOM OR ION, YTH domain-containing protein 1 | | 著者 | Tempel, W, Xu, C, Liu, K, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2014-08-15 | | 公開日 | 2014-09-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for selective binding of m(6)A RNA by the YTHDC1 YTH domain.
Nat.Chem.Biol., 10, 2014
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3KLL
 | | Crystal structure of Lactobacillus reuteri N-terminally truncated glucansucrase GTF180-maltose complex | | 分子名称: | CALCIUM ION, GLYCEROL, Glucansucrase, ... | | 著者 | Vujicic-Zagar, A, Pijning, T, Kralj, S, Eeuwema, W, Dijkhuizen, L, Dijkstra, B.W. | | 登録日 | 2009-11-08 | | 公開日 | 2010-11-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of a 117 kDa glucansucrase fragment provides insight into evolution and product specificity of GH70 enzymes
Proc.Natl.Acad.Sci.USA, 107, 2010
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4RDX
 | | Structure of histidinyl-tRNA synthetase in complex with tRNA(His) | | 分子名称: | ADENOSINE MONOPHOSPHATE, HISTIDINE, Histidine--tRNA ligase, ... | | 著者 | Xie, W, Tian, Q, Wang, C. | | 登録日 | 2014-09-20 | | 公開日 | 2015-03-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural basis for recognition of G-1-containing tRNA by histidyl-tRNA synthetase
Nucleic Acids Res., 43, 2015
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3KD3
 | | Crystal structure of a phosphoserine phosphohydrolase-like protein from Francisella tularensis subsp. tularensis SCHU S4 | | 分子名称: | GLYCEROL, MAGNESIUM ION, Phosphoserine phosphohydrolase-like protein | | 著者 | Nocek, B, Zhou, M, Peterson, S, Anderson, W, Joachimiak, A, CSGID, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2009-10-22 | | 公開日 | 2009-12-15 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of a phosphoserine phosphohydrolase-like protein from Francisella tularensis subsp. tularensis SCHUS4
TO BE PUBLISHED
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8V4U
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3KH3
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7WXZ
 | | Crystal structure of the recombinant protein HR121 from the S2 protein of SARS-CoV-2 | | 分子名称: | Spike protein S2' | | 著者 | Zheng, Y.T, Ouyang, S, Pang, W, Lu, Y, Zhao, Y.B. | | 登録日 | 2022-02-15 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | A variant-proof SARS-CoV-2 vaccine targeting HR1 domain in S2 subunit of spike protein.
Cell Res., 32, 2022
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3HNU
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3HP8
 | | Crystal structure of a designed Cyanovirin-N homolog lectin; LKAMG, bound to sucrose | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Cyanovirin-N-like protein, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | | 著者 | Koharudin, L.M.I, Furey, W, Gronenborn, A.M. | | 登録日 | 2009-06-03 | | 公開日 | 2009-06-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A designed chimeric cyanovirin-N homolog lectin: Structure and molecular basis of sucrose binding.
Proteins, 77, 2009
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4PNN
 | | Crystal Structure of human Tankyrase 2 in complex with 4HQN. | | 分子名称: | Tankyrase-2, ZINC ION, quinazolin-4(1H)-one | | 著者 | Qiu, W, Lam, R, Romanov, V, Gordon, R, Gebremeskel, S, Vodsedalek, J, Thompson, C, Beletskaya, I, Battaile, K.P, Pai, E.F, Chirgadze, N.Y. | | 登録日 | 2014-05-24 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2.
Acta Crystallogr.,Sect.D, 70, 2014
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3HS8
 | | Intersectin 1-peptide-AP2 alpha ear complex | | 分子名称: | Adaptor protein complex AP-2, alpha 2 subunit, peptide from Intersectin-1, ... | | 著者 | Vahedi-Faridi, A, Pechstein, A, Schaefer, J.G, Saenger, W, Haucke, V. | | 登録日 | 2009-06-10 | | 公開日 | 2010-02-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Regulation of synaptic vesicle recycling by complex formation between intersectin 1 and the clathrin adaptor complex AP2.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3HXF
 | | Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 32) | | 分子名称: | CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ... | | 著者 | Guo, Z, Alexandrov, K, Waldmann, H, Goody, R.S, Blankenfeldt, W. | | 登録日 | 2009-06-20 | | 公開日 | 2009-09-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Design, synthesis, and characterization of Peptide-based rab geranylgeranyl transferase inhibitors
J.Med.Chem., 52, 2009
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3HTO
 | | the hemagglutinin structure of an avian H1N1 influenza A virus | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Wang, G, Li, A, Zhang, Q, Wu, C, Zhang, R, Cai, Q, Song, W, Yuen, K.-Y. | | 登録日 | 2009-06-12 | | 公開日 | 2009-08-11 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | The hemagglutinin structure of an avian H1N1 influenza A virus
Virology, 392, 2009
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3HXC
 | | Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 8) | | 分子名称: | CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ... | | 著者 | Guo, Z, Alexandrov, K, Waldmann, H, Goody, R.S, Blankenfeldt, W. | | 登録日 | 2009-06-20 | | 公開日 | 2009-09-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Design, synthesis, and characterization of Peptide-based rab geranylgeranyl transferase inhibitors
J.Med.Chem., 52, 2009
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3I12
 | | The crystal structure of the D-alanyl-alanine synthetase A from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, D-alanine-D-alanine ligase A | | 著者 | Zhang, R, Maltseva, N, Papazisi, L, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2009-06-25 | | 公開日 | 2009-08-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The crystal structure of the D-alanyl-alanine synthetase A from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
To be Published
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4PDR
 | | Crystal Structure of a K+ selective NaK mutant in Barium and Sodium | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, BARIUM ION, Potassium channel protein, ... | | 著者 | Lam, Y, Zeng, W, Sauer, D.B, Jiang, Y. | | 登録日 | 2014-04-21 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | High Resolution Structural Views of Rubidium, Cesium and Barium Binding within a Potassium Selective Channel Filter
To Be Published
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