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PDB: 12479 件

3FWW
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The crystal structure of the bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase from Yersinia pestis CO92
分子名称: Bifunctional protein glmU
著者Zhang, R, Gu, M, Stam, J, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2009-01-19
公開日2009-03-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of the bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase from Yersinia pestis CO92
To be Published
8AK5
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BU of 8ak5 by Molmil
Human Sirt6 in complex with ADP-ribose and fragment pyroglutamic acid
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NAD-dependent protein deacetylase sirtuin-6, ...
著者You, W, Steegborn, C.
登録日2022-07-29
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
8AKB
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BU of 8akb by Molmil
Human Sirt6 in complex with ADP-ribose and fragment 4-nitrocatechol
分子名称: 1,2-ETHANEDIOL, 4-NITROCATECHOL, DI(HYDROXYETHYL)ETHER, ...
著者You, W, Steegborn, C.
登録日2022-07-29
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
3KKW
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BU of 3kkw by Molmil
Crystal structure of His-tagged form of PA4794 protein
分子名称: 1,2-ETHANEDIOL, Putative uncharacterized protein, SULFATE ION
著者Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2009-11-06
公開日2009-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Double trouble-Buffer selection and His-tag presence may be responsible for nonreproducibility of biomedical experiments.
Protein Sci., 23, 2014
3KLC
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BU of 3klc by Molmil
Crystal structure of hyperthermophilic nitrilase
分子名称: ACETIC ACID, BROMIDE ION, Beta ureidopropionase (Beta-alanine synthase), ...
著者Raczynska, J, Vorgias, C, Antranikian, G, Rypniewski, W.
登録日2009-11-07
公開日2010-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Crystallographic analysis of a thermoactive nitrilase.
J.Struct.Biol., 173, 2010
8AKF
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BU of 8akf by Molmil
Human Sirt6 in complex with ADP-ribose and fragment 3-aminobenzamide
分子名称: 1,2-ETHANEDIOL, 3-aminobenzamide, CHLORIDE ION, ...
著者You, W, Steegborn, C.
登録日2022-07-29
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
2KR7
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BU of 2kr7 by Molmil
solution structure of Helicobacter pylori SlyD
分子名称: FKBP-type peptidyl-prolyl cis-trans isomerase slyD
著者Cheng, T, Li, H, Xia, W, Sze, K, Sun, H.
登録日2009-12-07
公開日2010-12-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献solution structure of Helicobacter pylori SlyD
To be Published
8AK6
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BU of 8ak6 by Molmil
Human Sirt6 in complex with ADP-ribose and fragment sulfamethoxazole
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NAD-dependent protein deacetylase sirtuin-6, ...
著者You, W, Steegborn, C.
登録日2022-07-29
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
8AK9
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BU of 8ak9 by Molmil
Human Sirt6 in complex with ADP-ribose and fragment Isatin
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者You, W, Steegborn, C.
登録日2022-07-29
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
8AKD
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BU of 8akd by Molmil
Human Sirt6 in complex with ADP-ribose and fragment 1-methyl-L-histidine
分子名称: 4-METHYL-HISTIDINE, DI(HYDROXYETHYL)ETHER, NAD-dependent protein deacetylase sirtuin-6, ...
著者You, W, Steegborn, C.
登録日2022-07-29
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
8AK7
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BU of 8ak7 by Molmil
Human Sirt6 in complex with ADP-ribose and fragment 6-O-methylguanine
分子名称: 1,2-ETHANEDIOL, 6-O-methylguanine, CHLORIDE ION, ...
著者You, W, Steegborn, C.
登録日2022-07-29
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
8AKC
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BU of 8akc by Molmil
Human Sirt6 in complex with ADP-ribose and fragment 3-(acetylamino)thiophene-2-carboxylic acid
分子名称: 3-(acetylamino)thiophene-2-carboxylic acid, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者You, W, Steegborn, C.
登録日2022-07-29
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
1QR9
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BU of 1qr9 by Molmil
INHIBITION OF HIV-1 INFECTIVITY BY THE GP41 CORE: ROLE OF A CONSERVED HYDROPHOBIC CAVITY IN MEMBRANE FUSION
分子名称: GP41 ENVELOPE PROTEIN
著者Ji, H, Shu, W, Burling, F.T, Jiang, S.B, Lu, M.
登録日1999-06-18
公開日1999-11-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Inhibition of human immunodeficiency virus type 1 infectivity by the gp41 core: role of a conserved hydrophobic cavity in membrane fusion.
J.Virol., 73, 1999
2KQQ
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BU of 2kqq by Molmil
NMR structure of human insulin mutant gly-b8-d-ala, his-b10-asp, pro-b28-lys, lys-b29-pro, 20 structures
分子名称: Insulin A chain, Insulin B chain
著者Hua, Q.X, Wan, Z.L, Zhao, M, Jia, W, Huang, K, Weiss, M.A.
登録日2009-11-13
公開日2010-11-24
最終更新日2021-10-13
実験手法SOLUTION NMR
主引用文献Structure and Dynamics of an Turn-Stabilize But Ina Insulin Analog.
To be Published
8AKA
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BU of 8aka by Molmil
Human Sirt6 in complex with ADP-ribose and fragment cis-resveratrol
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者You, W, Steegborn, C.
登録日2022-07-29
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
8AKE
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BU of 8ake by Molmil
Human Sirt6 in complex with ADP-ribose and fragment nicotinamide
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NAD-dependent protein deacetylase sirtuin-6, ...
著者You, W, Steegborn, C.
登録日2022-07-29
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
3K3T
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BU of 3k3t by Molmil
E185A mutant of peptidoglycan hydrolase from Sphingomonas sp. A1
分子名称: Peptidoglycan hydrolase FlgJ, SULFATE ION
著者Maruyama, Y, Ochiai, A, Itoh, T, Mikami, B, Hashimoto, W, Murata, K.
登録日2009-10-04
公開日2010-07-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mutational studies of the peptidoglycan hydrolase FlgJ of Sphingomonas sp. strain A1
J.Basic Microbiol., 50, 2010
8AK8
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BU of 8ak8 by Molmil
Human Sirt6 in complex with ADP-ribose and fragment 4-hydroxybenzamide
分子名称: 4-HYDROXYBENZAMIDE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者You, W, Steegborn, C.
登録日2022-07-29
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
8AKG
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BU of 8akg by Molmil
Human Sirt6 in complex with ADP-ribose and fragment 4-amino-6-chlorobenzene-1,3-disulfonamide
分子名称: 1,2-ETHANEDIOL, 4-AMINO-6-CHLOROBENZENE-1,3-DISULFONAMIDE, CHLORIDE ION, ...
著者You, W, Steegborn, C.
登録日2022-07-29
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
8AMC
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BU of 8amc by Molmil
Crystal Structure of cat allergen Fel d 4
分子名称: Allergen Fel d 4, SULFATE ION
著者Schooltink, L, Sagmeister, T, Gottstein, N, Pavkov-Keller, T, Keller, W.
登録日2022-08-03
公開日2023-08-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal Structure of cat allergen Fel d 4
To Be Published
3JZ9
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BU of 3jz9 by Molmil
Crystal structure of the GEF domain of DrrA/SidM from Legionella pneumophila
分子名称: Uncharacterized protein DrrA
著者Schoebel, S, Oesterlin, L.K, Blankenfeldt, W, Goody, R.S, Itzen, A.
登録日2009-09-23
公開日2010-01-19
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity.
Mol.Cell, 36, 2009
3CKL
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BU of 3ckl by Molmil
Crystal structure of human cytosolic sulfotransferase SULT1B1 in complex with PAP and resveratrol
分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, RESVERATROL, Sulfotransferase family cytosolic 1B member 1
著者Pan, P.W, Tempel, W, Dong, A, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2008-03-16
公開日2008-04-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of human cytosolic sulfotransferase SULT1B1 in complex with PAP and resveratrol.
To be Published
1P1E
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BU of 1p1e by Molmil
Structural Insights into the Inter-domain Chaperoning of Tandem PDZ Domains in Glutamate Receptor Interacting Proteins
分子名称: Glutamate receptor interacting protein
著者Feng, W, Shi, Y, Li, M, Zhang, M.
登録日2003-04-12
公開日2003-11-11
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Tandem PDZ repeats in glutamate receptor-interacting proteins have a novel mode of PDZ domain-mediated target binding
Nat.Struct.Biol., 10, 2003
3CXL
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BU of 3cxl by Molmil
Crystal structure of human chimerin 1 (CHN1)
分子名称: N-chimerin, UNKNOWN ATOM OR ION, ZINC ION
著者Shen, L, Buck, M, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Wilkstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2008-04-24
公開日2008-08-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of human chimerin 1 (CHN1).
To be Published
1OWH
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Substituted 2-Naphthamidine Inhibitors of Urokinase
分子名称: 6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENYL]-2-NAPHTHAMIDE, SULFATE ION, Urokinase-type plasminogen activator
著者Wendt, M.D, Rockway, T.W, Geyer, A, McClellan, W, Weitzberg, M, Zhao, X, Mantei, R, Nienaber, V.L, Stewart, K, Klinghofer, V, Giranda, V.L.
登録日2003-03-28
公開日2003-09-30
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Identification of Novel Binding Interactions in the Development of Potent, Selective 2-Naphthamidine Inhibitors of Urokinase. Synthesis, Structural Analysis, and SAR of N-Phenyl Amide 6-Substitution.
J.Med.Chem., 47, 2004

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件を2024-07-10に公開中

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