8SCR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8scr by Molmil](/molmil-images/mine/8scr) | Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 4h | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | Authors: | Fang, Z, Lelyveld, V.S, Szostak, J.W. | Deposit date: | 2023-04-05 | Release date: | 2023-10-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
|
|
6Y0R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y0r by Molmil](/molmil-images/mine/6y0r) | Chitooligosaccharide oxidase | Descriptor: | Chitooligosaccharide oxidase, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Savino, S, Fraaije, M.W. | Deposit date: | 2020-02-10 | Release date: | 2020-06-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.611 Å) | Cite: | Analysis of the structure and substrate scope of chitooligosaccharide oxidase reveals high affinity for C2-modified glucosamines. Febs Lett., 594, 2020
|
|
8SCS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8scs by Molmil](/molmil-images/mine/8scs) | Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 8h | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | Authors: | Fang, Z, Lelyveld, V.S, Szostak, J.W. | Deposit date: | 2023-04-05 | Release date: | 2023-10-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
|
|
5AGV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5agv by Molmil](/molmil-images/mine/5agv) | The sliding clamp of Mycobacterium tuberculosis in complex with a natural product. | Descriptor: | (R,R)-2,3-BUTANEDIOL, CALCIUM ION, CYCLOHEXYL GRISELIMYCIN, ... | Authors: | Lukat, P, Kling, A, Heinz, D.W, Mueller, R. | Deposit date: | 2015-02-03 | Release date: | 2015-06-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins. Science, 348, 2015
|
|
8SCT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sct by Molmil](/molmil-images/mine/8sct) | Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 24h | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | Authors: | Fang, Z, Lelyveld, V.S, Szostak, J.W. | Deposit date: | 2023-04-05 | Release date: | 2023-10-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
|
|
7N8L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n8l by Molmil](/molmil-images/mine/7n8l) | |
8SCU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8scu by Molmil](/molmil-images/mine/8scu) | Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 48h (Product State) | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | Authors: | Fang, Z, Lelyveld, V.S, Szostak, J.W. | Deposit date: | 2023-04-05 | Release date: | 2023-10-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
|
|
1IF0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1if0 by Molmil](/molmil-images/mine/1if0) | PSEUDO-ATOMIC MODEL OF BACTERIOPHAGE HK97 PROCAPSID (PROHEAD II) | Descriptor: | PROTEIN (MAJOR CAPSID PROTEIN GP5) | Authors: | Conway, J.F, Wikoff, W.R, Cheng, N, Duda, R.L, Hendrix, R.W, Johnson, J.E, Steven, A.C. | Deposit date: | 2001-04-11 | Release date: | 2001-05-02 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | Virus maturation involving large subunit rotations and local refolding. Science, 292, 2001
|
|
7N8M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n8m by Molmil](/molmil-images/mine/7n8m) | |
7N8E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n8e by Molmil](/molmil-images/mine/7n8e) | |
8HQI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hqi by Molmil](/molmil-images/mine/8hqi) | |
5DZB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dzb by Molmil](/molmil-images/mine/5dzb) | 6beta1 | Descriptor: | 6beta1 | Authors: | Kabasakal, B.V, MacDonald, J.T, Murray, W.W. | Deposit date: | 2015-09-25 | Release date: | 2016-08-31 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.33 Å) | Cite: | Synthetic beta-solenoid proteins with the fragment-free computational design of a beta-hairpin extension. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
6U7O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u7o by Molmil](/molmil-images/mine/6u7o) | HIV-1 wild type protease with GRL-00819A, with phenyl-boronic-acid as P2'-ligand and with a 6-5-5-ring fused crown-like tetrahydropyranofuran as the P2-ligand | Descriptor: | CHLORIDE ION, FORMIC ACID, GLYCEROL, ... | Authors: | Wang, Y.-F, Kneller, D.W, Weber, I.T. | Deposit date: | 2019-09-03 | Release date: | 2019-10-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Potent HIV-1 Protease Inhibitors Containing Carboxylic and Boronic Acids: Effect on Enzyme Inhibition and Antiviral Activity and Protein-Ligand X-ray Structural Studies. Chemmedchem, 14, 2019
|
|
5AA8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5aa8 by Molmil](/molmil-images/mine/5aa8) | Structure of C1156Y,L1198F Mutant Human Anaplastic Lymphoma Kinase in Complex with PF-06463922 ((10R)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile). | Descriptor: | (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile, ALK TYROSINE KINASE RECEPTOR | Authors: | McTigue, M, Deng, Y.-L, Liu, W, Brooun, A, Stewart, A. | Deposit date: | 2015-07-23 | Release date: | 2016-06-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Resensitization to Crizotinib by the Lorlatinib Alk Resistance Mutation L1198F. N.Engl.J.Med., 374, 2016
|
|
3HM6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hm6 by Molmil](/molmil-images/mine/3hm6) | Crystal structure of the cytoplasmic domain of human plexin B1 | Descriptor: | Plexin-B1, UNKNOWN ATOM OR ION, Unknown peptide | Authors: | Tong, Y, He, H, Shen, L, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-05-28 | Release date: | 2009-06-09 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.402 Å) | Cite: | Structure and function of the intracellular region of the plexin-b1 transmembrane receptor. J.Biol.Chem., 284, 2009
|
|
5XS4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xs4 by Molmil](/molmil-images/mine/5xs4) | Structure of Coxsackievirus A6 (CVA6) virus A-particle | Descriptor: | Genome polyprotein | Authors: | Zheng, Q.B, He, M.Z, Xu, L.F, Yu, H, Li, S.W, Cheng, T. | Deposit date: | 2017-06-12 | Release date: | 2017-09-27 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody Nat Commun, 8, 2017
|
|
5DQA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dqa by Molmil](/molmil-images/mine/5dqa) | t3284 loop variant of beta1 | Descriptor: | t3284 | Authors: | Kabasakal, B.V, MacDonald, J.T, Murray, W.W. | Deposit date: | 2015-09-14 | Release date: | 2016-08-31 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.27 Å) | Cite: | Synthetic beta-solenoid proteins with the fragment-free computational design of a beta-hairpin extension. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
4HO8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ho8 by Molmil](/molmil-images/mine/4ho8) | Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with UDP-glucose and thymidine | Descriptor: | Glucose-1-phosphate thymidylyltransferase, SULFATE ION, THYMIDINE, ... | Authors: | Chen, T.J, Chien, W.T, Lin, C.C, Wang, W.C. | Deposit date: | 2012-10-22 | Release date: | 2013-10-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with UDP-glucose and thymidine TO BE PUBLISHED
|
|
8I7L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8i7l by Molmil](/molmil-images/mine/8i7l) | Crystal structure of indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with a novel inhibitor | Descriptor: | 1-[3-[(4-chloranyl-2-fluoranyl-phenyl)carbamoylamino]-4-[cyclohexyl(2-methylpropyl)amino]phenyl]pyrrole-2-carboxylic acid, Indoleamine 2,3-dioxygenase 1, THIOSULFATE | Authors: | Li, K, Liu, W, Dong, X. | Deposit date: | 2023-02-01 | Release date: | 2023-02-15 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Apo-Form Selective Inhibition of IDO for Tumor Immunotherapy. J Immunol., 209, 2022
|
|
4PQG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pqg by Molmil](/molmil-images/mine/4pqg) | Crystal structure of the pneumococcal O-GlcNAc transferase GtfA in complex with UDP and GlcNAc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycosyltransferase Gtf1, URIDINE-5'-DIPHOSPHATE | Authors: | Shi, W.W, Jiang, Y.L, Zhu, F, Yang, Y.H, Wu, H, Ren, Y.M, Chen, Y, Zhou, C.Z. | Deposit date: | 2014-03-03 | Release date: | 2014-06-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of a Novel O-Linked N-Acetyl-d-glucosamine (O-GlcNAc) Transferase, GtfA, Reveals Insights into the Glycosylation of Pneumococcal Serine-rich Repeat Adhesins. J.Biol.Chem., 289, 2014
|
|
3NV6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nv6 by Molmil](/molmil-images/mine/3nv6) | Crystal Structure of Camphor-Bound CYP101D2 | Descriptor: | CAMPHOR, Cytochrome P450, DI(HYDROXYETHYL)ETHER, ... | Authors: | Yang, W, Bell, S.G, Wang, H, Zhou, W.H, Bartlam, M, Wong, L.L, Rao, Z. | Deposit date: | 2010-07-08 | Release date: | 2010-11-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The structure of CYP101D2 unveils a potential path for substrate entry into the active site Biochem.J., 433, 2011
|
|
1WVB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wvb by Molmil](/molmil-images/mine/1wvb) | Crystal structure of human arginase I: the mutant E256Q | Descriptor: | Arginase 1, MANGANESE (II) ION, S-2-(BORONOETHYL)-L-CYSTEINE | Authors: | Di Costanzo, L, Guadalupe, S, Mora, A, Centeno, F, Christianson, D.W. | Deposit date: | 2004-12-14 | Release date: | 2005-09-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of human arginase I: the mutant E256Q To be Published
|
|
4M9X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m9x by Molmil](/molmil-images/mine/4m9x) | Crystal structure of CED-4 bound CED-3 fragment | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CED-3 fragment, Cell death protein 4, ... | Authors: | Huang, W.J, Jinag, T.Y, Choi, W.Y, Wang, J.W, Shi, Y.G. | Deposit date: | 2013-08-15 | Release date: | 2013-10-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.344 Å) | Cite: | Mechanistic insights into CED-4-mediated activation of CED-3. Genes Dev., 27, 2013
|
|
1P7S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1p7s by Molmil](/molmil-images/mine/1p7s) | T4 LYSOZYME CORE REPACKING MUTANT V103I/TA | Descriptor: | LYSOZYME | Authors: | Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W. | Deposit date: | 2003-05-05 | Release date: | 2003-10-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Repacking the Core of T4 Lysozyme by Automated Design J.Mol.Biol., 332, 2003
|
|
7MX0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mx0 by Molmil](/molmil-images/mine/7mx0) | The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988558 | Descriptor: | 2-(2,6-difluorophenyl)-5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-6-oxo-3,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... | Authors: | Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. | Deposit date: | 2021-05-17 | Release date: | 2022-05-18 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988558 To Be Published
|
|