5LYP
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![BU of 5lyp by Molmil](/molmil-images/mine/5lyp) | Crystal structure of the Tpr Domain of Sgt2. | 分子名称: | BORATE ION, Small glutamine-rich tetratricopeptide repeat-containing protein 2 | 著者 | Krysztofinska, E.M, Morgan, R.M.L, Thapaliya, A, Evans, N.J, Murray, J.W, Martinez-Lumbreras, S, Isaacson, R.L. | 登録日 | 2016-09-28 | 公開日 | 2017-10-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp. Front Mol Biosci, 4, 2017
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5UH9
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![BU of 5uh9 by Molmil](/molmil-images/mine/5uh9) | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 2nt RNA | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | 登録日 | 2017-01-11 | 公開日 | 2017-04-12 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (4.402 Å) | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
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4YC5
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![BU of 4yc5 by Molmil](/molmil-images/mine/4yc5) | Beta1 synthetic solenoid protein | 分子名称: | CHLORIDE ION, beta1 | 著者 | Murray, J.W. | 登録日 | 2015-02-19 | 公開日 | 2016-03-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.755 Å) | 主引用文献 | Synthetic beta-solenoid proteins with the fragment-free computational design of a beta-hairpin extension. Proc.Natl.Acad.Sci.USA, 113, 2016
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3RUB
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![BU of 3rub by Molmil](/molmil-images/mine/3rub) | CRYSTAL STRUCTURE OF THE UNACTIVATED FORM OF RIBULOSE-1,5-BISPHOSPHATE CARBOXYLASE(SLASH)OXYGENASE FROM TOBACCO REFINED AT 2.0-ANGSTROMS RESOLUTION | 分子名称: | ASPARAGINE, RIBULOSE 1,5-BISPHOSPHATE CARBOXYLASE/OXYGENASE, FORM III, ... | 著者 | Schreuder, H, Cascio, D, Curmi, P.M.G, Chapman, M.S, Suh, S.W, Eisenberg, D.S. | 登録日 | 1990-05-25 | 公開日 | 1992-10-15 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the unactivated form of ribulose-1,5-bisphosphate carboxylase/oxygenase from tobacco refined at 2.0-A resolution. J.Biol.Chem., 267, 1992
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4YEC
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![BU of 4yec by Molmil](/molmil-images/mine/4yec) | |
5M04
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![BU of 5m04 by Molmil](/molmil-images/mine/5m04) | Structure of ObgE from Escherichia coli | 分子名称: | GTPase ObgE/CgtA, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Gkekas, S, Singh, R.K, Versees, W. | 登録日 | 2016-10-03 | 公開日 | 2017-03-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural and biochemical analysis of Escherichia coli ObgE, a central regulator of bacterial persistence. J. Biol. Chem., 292, 2017
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4EIN
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![BU of 4ein by Molmil](/molmil-images/mine/4ein) | Crystal structure of mouse thymidylate synthase in binary complex with a substrate analogue and strong inhibitor, N(4)-hydroxy-2'-deoxycytidine-5'-monophosphate | 分子名称: | 2'-deoxy-N-hydroxycytidine 5'-(dihydrogen phosphate), GLYCEROL, Thymidylate synthase | 著者 | Dowiercial, A, Jarmula, A, Rypniewski, W.R, Wilk, P, Kierdaszuk, B, Rode, W. | 登録日 | 2012-04-05 | 公開日 | 2013-04-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structures of complexes of mouse thymidylate synthase
crystallized with N4-OH-dCMP alone or in the presence of
N5,10-methylenetetrahydrofolate PTERIDINES, 2013
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4YGK
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![BU of 4ygk by Molmil](/molmil-images/mine/4ygk) | NaSCN--Interactions between Hofmeister Anions and the Binding Pocket of a Protein | 分子名称: | Carbonic anhydrase 2, HYDROXIDE ION, THIOCYANATE ION, ... | 著者 | Fox, J.M, Kang, K, Sherman, W, Heroux, A, Sastry, G.M, Baghbanzadeh, M, Lockett, M.R, Whitesides, G.M. | 登録日 | 2015-02-26 | 公開日 | 2015-03-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Interactions between Hofmeister Anions and the Binding Pocket of a Protein. J.Am.Chem.Soc., 137, 2015
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1G2V
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![BU of 1g2v by Molmil](/molmil-images/mine/1g2v) | THE STRUCTURAL BASIS OF THE CATALYTIC MECHANISM AND REGULATION OF GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (RMLA). TTP COMPLEX. | 分子名称: | GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, THYMIDINE-5'-TRIPHOSPHATE | 著者 | Blankenfeldt, W, Asuncion, M, Lam, J.S, Naismith, J.H. | 登録日 | 2000-10-21 | 公開日 | 2000-12-27 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The structural basis of the catalytic mechanism and regulation of glucose-1-phosphate thymidylyltransferase (RmlA). EMBO J., 19, 2000
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1K5N
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![BU of 1k5n by Molmil](/molmil-images/mine/1k5n) | HLA-B*2709 BOUND TO NONA-PEPTIDE M9 | 分子名称: | GLYCEROL, beta-2-microglobulin, light chain, ... | 著者 | Hulsmeyer, M, Hillig, R.C, Volz, A, Ruhl, M, Schroder, W, Saenger, W, Ziegler, A, Uchanska-Ziegler, B. | 登録日 | 2001-10-11 | 公開日 | 2002-10-30 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | HLA-B27 Subtypes Differentially Associated with Disease Exhibit Subtle Structural Alterations J.Biol.Chem., 277, 2002
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7WMZ
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![BU of 7wmz by Molmil](/molmil-images/mine/7wmz) | |
5LNT
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![BU of 5lnt by Molmil](/molmil-images/mine/5lnt) | Crystal structure of Arabidopsis thaliana Pdx1K166R-preI320 complex | 分子名称: | PHOSPHATE ION, Pyridoxal 5'-phosphate synthase subunit PDX1.1, [(~{E},4~{S})-4-azanyl-3-oxidanylidene-pent-1-enyl] dihydrogen phosphate | 著者 | Rodrigues, M.J, Windeisen, V, Zhang, Y, Guedez, G, Weber, S, Strohmeier, M, Hanes, J.W, Royant, A, Evans, G, Sinning, I, Ealick, S.E, Begley, T.P, Tews, I. | 登録日 | 2016-08-06 | 公開日 | 2017-01-18 | 最終更新日 | 2017-02-22 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis. Nat. Chem. Biol., 13, 2017
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4H9O
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![BU of 4h9o by Molmil](/molmil-images/mine/4h9o) | Complex structure 2 of DAXX/H3.3(sub5,G90M)/H4 | 分子名称: | Death domain-associated protein 6, Histone H3.3, Histone H4, ... | 著者 | Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J. | 登録日 | 2012-09-24 | 公開日 | 2012-10-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.053 Å) | 主引用文献 | DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out To be Published
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1ES9
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![BU of 1es9 by Molmil](/molmil-images/mine/1es9) | X-RAY CRYSTAL STRUCTURE OF R22K MUTANT OF THE MAMMALIAN BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASES (PAF-AH) | 分子名称: | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB GAMMA SUBUNIT | 著者 | McMullen, T.W.P, Li, J, Sheffield, P.J, Aoki, J, Martin, T.W, Arai, H, Inoue, K, Derewenda, Z.S. | 登録日 | 2000-04-07 | 公開日 | 2000-05-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The functional implications of the dimerization of the catalytic subunits of the mammalian brain platelet-activating factor acetylhydrolase (Ib). Protein Eng., 13, 2000
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4EPI
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![BU of 4epi by Molmil](/molmil-images/mine/4epi) | The crystal structure of pesticin-T4 lysozyme hybrid stabilized by engineered disulfide bonds | 分子名称: | Pesticin, Lysozyme Chimera, SODIUM ION, ... | 著者 | Seddiki, N, Fairman, J.W, Noinaj, N, Lukacik, P, Barnard, T, Buchanan, S.K. | 登録日 | 2012-04-17 | 公開日 | 2012-06-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Structural engineering of a phage lysin that targets Gram-negative pathogens. Proc.Natl.Acad.Sci.USA, 109, 2012
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1K7D
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![BU of 1k7d by Molmil](/molmil-images/mine/1k7d) | Penicillin Acylase with Phenyl Proprionic Acid | 分子名称: | CALCIUM ION, Penicillin Acylase alpha subunit, R-2-PHENYL-PROPRIONIC ACID, ... | 著者 | Hensgens, C.M.H, Keizer, E, Snijder, H.J, Dijkstra, B.W. | 登録日 | 2001-10-19 | 公開日 | 2003-09-02 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural and kinetic studies on ligand binding in wild-type and active-site mutants of penicillin acylase. Protein Eng.Des.Sel., 17, 2004
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6NAQ
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![BU of 6naq by Molmil](/molmil-images/mine/6naq) | Crystal structure of Neisseria meningitidis ClpP protease in Apo form | 分子名称: | ATP-dependent Clp protease proteolytic subunit, POTASSIUM ION | 著者 | Houry, W.A, Mabanglo, M.F, Pai, E.F, Eger, B.T, Bryson, S. | 登録日 | 2018-12-06 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.022 Å) | 主引用文献 | ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores. Commun Biol, 2, 2019
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4H9R
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![BU of 4h9r by Molmil](/molmil-images/mine/4h9r) | Complex structure 5 of DAXX(E225A)/H3.3(sub5,G90A)/H4 | 分子名称: | Death domain-associated protein 6, Histone H3.3, Histone H4, ... | 著者 | Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J. | 登録日 | 2012-09-24 | 公開日 | 2012-10-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.197 Å) | 主引用文献 | DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out To be Published
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4YC2
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![BU of 4yc2 by Molmil](/molmil-images/mine/4yc2) | |
4YBL
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![BU of 4ybl by Molmil](/molmil-images/mine/4ybl) | |
3SRF
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![BU of 3srf by Molmil](/molmil-images/mine/3srf) | Human M1 pyruvate kinase | 分子名称: | GLYCEROL, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Morgan, H.P, O'Reilly, F, Palmer, R, McNae, I.W, Nowicki, M.W, Wear, M.A, Fothergill-Gilmore, L.A, Walkinshaw, M.D. | 登録日 | 2011-07-07 | 公開日 | 2012-08-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.845 Å) | 主引用文献 | Allosetric regulation of M2 pyruvate kinase. To be Published
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7WPQ
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![BU of 7wpq by Molmil](/molmil-images/mine/7wpq) | Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 3.27 angstron resolution (2 units) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ... | 著者 | Zeng, J.W, Shu, Z.M, Zhou, A.W. | 登録日 | 2022-01-24 | 公開日 | 2022-05-25 | 最終更新日 | 2022-06-15 | 実験手法 | ELECTRON MICROSCOPY (3.267 Å) | 主引用文献 | Structural basis of von Willebrand factor multimerization and tubular storage. Blood, 139, 2022
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4YFO
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![BU of 4yfo by Molmil](/molmil-images/mine/4yfo) | beta1_ex1 | 分子名称: | beta1_ex1 | 著者 | Murray, J.W, MacDonald, J.T. | 登録日 | 2015-02-25 | 公開日 | 2016-03-16 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.39 Å) | 主引用文献 | Synthetic beta-solenoid proteins with the fragment-free computational design of a beta-hairpin extension. Proc.Natl.Acad.Sci.USA, 113, 2016
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4GSQ
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![BU of 4gsq by Molmil](/molmil-images/mine/4gsq) | Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains | 分子名称: | CALCIUM ION, GLYCEROL, Probable conserved lipoprotein LPPS | 著者 | Kim, H.S, Kim, J, Im, H.N, Yoon, J.Y, An, D.R, Yoon, H.J, Kim, J.Y, Min, H.K, Kim, S.-J, Lee, J.Y, Han, B.W, Suh, S.W. | 登録日 | 2012-08-28 | 公開日 | 2013-02-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains Acta Crystallogr.,Sect.D, 69, 2013
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3SX0
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![BU of 3sx0 by Molmil](/molmil-images/mine/3sx0) | Crystal structure of Dot1l in complex with a brominated SAH analog | 分子名称: | (2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}sulfanyl)butanoic acid (non-preferred name), Histone-lysine N-methyltransferase, H3 lysine-79 specific, ... | 著者 | Yu, W, Tempel, W, Smil, D, Schapira, M, Li, Y, Vedadi, M, Nguyen, K.T, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Brown, P.J, Structural Genomics Consortium (SGC) | 登録日 | 2011-07-14 | 公開日 | 2011-07-27 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Bromo-deaza-SAH: a potent and selective DOT1L inhibitor. Bioorg. Med. Chem., 21, 2013
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