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PDB: 34568 件

8B2H
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Muramidase from Thermothielavioides terrestris, catalytic domain
分子名称: 1,2-ETHANEDIOL, SH3b domain-containing protein, ZINC ION
著者Moroz, O.V, Blagova, E, Lebedev, A.A, Skov, L.K, Pache, R.A, Schnorr, K.M, Kiemer, L, Nymand-Grarup, S, Ming, L, Ye, L, Klausen, M, Cohn, M.T, Schmidt, E.G.W, Davies, G.J, Wilson, K.S.
登録日2022-09-13
公開日2023-07-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Module walking using an SH3-like cell-wall-binding domain leads to a new GH184 family of muramidases.
Acta Crystallogr D Struct Biol, 79, 2023
2W6I
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Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration: Hydration State 4B.
分子名称: ATP SYNTHASE SUBUNIT ALPHA HEART ISOFORM, MITOCHONDRIAL, ATP SYNTHASE SUBUNIT BETA, ...
著者Sanchez-Weatherby, J, Felisaz, F, Gobbo, A, Huet, J, Ravelli, R.B.G, Bowler, M.W, Cipriani, F.
登録日2008-12-18
公開日2009-10-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Improving diffraction by humidity control: a novel device compatible with X-ray beamlines.
Acta Crystallogr. D Biol. Crystallogr., 65, 2009
168D
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STABILIZING EFFECTS OF THE RNA 2'-SUBSTITUENT: CRYSTAL STRUCTURE OF AN OLIGODEOXYNUCLEOTIDE DUPLEX CONTAINING 2'-O-METHYLATED ADENOSINES
分子名称: DNA/RNA (5'-D(*GP*CP*GP*TP*)-R(*(A2M)P*)-D(*TP*AP*CP*GP*C)-3')
著者Lubini, P, Zuercher, W, Egli, M.
登録日1994-04-08
公開日1994-08-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Stabilizing effects of the RNA 2'-substituent: crystal structure of an oligodeoxynucleotide duplex containing 2'-O-methylated adenosines.
Chem.Biol., 1, 1994
6BIV
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HLA-DRB1 in complex with citrullinated LL37 peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ...
著者Ting, Y.T, Scally, S.W, Rossjohn, J.
登録日2017-11-03
公開日2018-01-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.
J. Biol. Chem., 293, 2018
1RHK
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Crystal structure of the complex of caspase-3 with a phenyl-propyl-ketone inhibitor
分子名称: Caspase-3, acetyl-asp-glu-val-fpr
著者Becker, J.W, Rotonda, J, Soisson, S.M.
登録日2003-11-14
公開日2004-05-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis.
J.Med.Chem., 47, 2004
7U6Y
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Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of glibenclamide and ATP with Kir6.2-CTD in the down conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11
著者Shyng, S.L, Sung, M.W, Driggers, C.M.
登録日2022-03-06
公開日2022-08-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
6HQM
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Crystal structure of GcoA F169I bound to guaiacol
分子名称: Cytochrome P450, Guaiacol, PROTOPORPHYRIN IX CONTAINING FE
著者Mallinson, S.J.B, Hinchen, D.J, Allen, M.D, Johnson, C.W, Beckham, G.T, McGeehan, J.E.
登録日2018-09-25
公開日2019-07-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Enabling microbial syringol conversion through structure-guided protein engineering.
Proc.Natl.Acad.Sci.USA, 116, 2019
7U7M
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Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the up conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11
著者Shyng, S.L, Sung, M.W, Driggers, C.M.
登録日2022-03-07
公開日2022-08-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
1A36
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TOPOISOMERASE I/DNA COMPLEX
分子名称: DNA (5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*A P*TP*TP*TP*TP*T)- 3'), DNA (5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*C P*TP*TP*TP*TP*T)- 3'), TOPOISOMERASE I
著者Stewart, L, Redinbo, M.R, Qiu, X, Champoux, J.J, Hol, W.G.J.
登録日1998-01-29
公開日1998-08-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A model for the mechanism of human topoisomerase I.
Science, 279, 1998
7U2X
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Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the down conformation
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Shyng, S.L, Sung, M.W, Driggers, C.M.
登録日2022-02-25
公開日2022-08-31
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
150L
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BU of 150l by Molmil
CONSERVATION OF SOLVENT-BINDING SITES IN 10 CRYSTAL FORMS OF T4 LYSOZYME
分子名称: T4 LYSOZYME
著者Faber, H.R, Matthews, B.W.
登録日1994-01-25
公開日1994-04-30
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conservation of solvent-binding sites in 10 crystal forms of T4 lysozyme.
Protein Sci., 3, 1994
2W6H
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BU of 2w6h by Molmil
Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration: Hydration State 4A.
分子名称: ATP SYNTHASE SUBUNIT ALPHA HEART ISOFORM, MITOCHONDRIAL, ATP SYNTHASE SUBUNIT BETA, ...
著者Sanchez-Weatherby, J, Felisaz, F, Gobbo, A, Huet, J, Ravelli, R.B.G, Bowler, M.W, Cipriani, F.
登録日2008-12-18
公開日2009-10-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (5 Å)
主引用文献Improving diffraction by humidity control: a novel device compatible with X-ray beamlines.
Acta Crystallogr. D Biol. Crystallogr., 65, 2009
1A3W
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PYRUVATE KINASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH FBP, PG, MN2+ AND K+
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 2-PHOSPHOGLYCOLIC ACID, MANGANESE (II) ION, ...
著者Jurica, M.S, Mesecar, A, Heath, P.J, Shi, W, Nowak, T, Stoddard, B.L.
登録日1998-01-26
公開日1998-05-27
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate.
Structure, 6, 1998
6HAY
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BU of 6hay by Molmil
Crystal structure of PROTAC 1 in complex with the bromodomain of human SMARCA2 and pVHL:ElonginC:ElonginB
分子名称: (2~{S},4~{R})-~{N}-[[2-[2-[2-[2-[4-[3-azanyl-6-(2-hydroxyphenyl)pyridazin-4-yl]piperazin-1-yl]ethoxy]ethoxy]ethoxy]-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Roy, M, Bader, G, Diers, E, Trainor, N, Farnaby, W, Ciulli, A.
登録日2018-08-09
公開日2019-06-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design.
Nat.Chem.Biol., 15, 2019
1RHR
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BU of 1rhr by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-3 WITH A CINNAMIC ACID METHYL ESTER INHIBITOR
分子名称: (3S)-5-[(2-CHLORO-6-FLUOROBENZYL)SULFANYL]-3-{[N-({2-ETHOXY-5-[(1E)-3-METHOXY-3-OXOPROP-1-ENYL]PHENYL}ACETYL)-D-VALYL]AMINO}-4-OXOPENTANOIC ACID, Caspase-3
著者Becker, J.W, Rotonda, J, Soisson, S.M.
登録日2003-11-14
公開日2004-05-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis.
J.Med.Chem., 47, 2004
5EEI
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Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with SAHA
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ...
著者Hai, Y, Christianson, D.W.
登録日2015-10-22
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
2W8H
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Crystal structure of spin labeled Wza24-345.
分子名称: CHLORIDE ION, PUTATIVE OUTER MEMBRANE LIPOPROTEIN WZA, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
著者Hagelueken, G, Ingledew, W.J, Huang, H, Petrovic-Stojanovska, B, Whitfield, C, ElMkami, H, Schiemann, O, Naismith, J.H.
登録日2009-01-16
公開日2009-02-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Peldor Distance Fingerprinting of the Octameric Outer-Membrane Protein Wza from Escherichia Coli.
Angew.Chem.Int.Ed.Engl., 48, 2009
3JQH
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Structure of the neck region of the glycan-binding receptor DC-SIGNR
分子名称: C-type lectin domain family 4 member M
著者Feinberg, H, Tso, C.K.W, Taylor, M.E, Drickamer, K, Weis, W.I.
登録日2009-09-06
公開日2009-11-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Segmented helical structure of the neck region of the glycan-binding receptor DC-SIGNR.
J.Mol.Biol., 394, 2009
8TS4
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BU of 8ts4 by Molmil
Crystal structure of T. Brucei hypoxanthine guanine phosphoribosyltransferase in complex with [2S,4S]-4-Guanin-9-yl-2-(2-phosphonoethoxymethyl)-1-N-(3-phosphonopropionyl)pyrrolidine
分子名称: (3-{(2S,4S)-4-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-[(2-phosphonoethoxy)methyl]pyrrolidin-1-yl}-3-oxopropyl)phosphonic acid, Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION
著者Guddat, L.W, Guddat, L.W.
登録日2023-08-10
公開日2024-05-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Development of Prolinol Containing Inhibitors of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase: Rational Structure-Based Drug Design.
J.Med.Chem., 67, 2024
6BSR
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Crystal structure of penicillin-binding protein 4 (PBP4) from Enterococcus faecalis in the benzylpenicillin bound form.
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Moon, T.M, D'Andrea, E.D, Peti, W, Page, R.
登録日2017-12-04
公開日2018-10-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
6BTJ
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Crystal structure of pan-H7, anti-hemagglutinin monoclonal antibody H7.5 (Fab fragment)
分子名称: Heavy chain of H7.5 Fab, Light chain of H7.5 Fab
著者Shanshan, L, Ian, A.W.
登録日2017-12-06
公開日2018-12-19
最終更新日2023-02-22
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Crystal structure of pan-H7, anti-hemagglutinin monoclonal antibody H7.5 (Fab fragment)
To Be Published
5ADY
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Cryo-EM structures of the 50S ribosome subunit bound with HflX
分子名称: 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L10, ...
著者Zhang, Y, Mandava, C.S, Cao, W, Li, X, Zhang, D, Li, N, Zhang, Y, Zhang, X, Qin, Y, Mi, K, Lei, J, Sanyal, S, Gao, N.
登録日2015-08-25
公開日2015-10-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Hflx is a Ribosome Splitting Factor Rescuing Stalled Ribosomes Under Stress Conditions
Nat.Struct.Mol.Biol., 22, 2015
7U5J
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Cryo-EM Structure of ALDOA
分子名称: Fructose-bisphosphate aldolase
著者Morgan, C.E, Zhang, Z, Yu, E.W.
登録日2022-03-02
公開日2022-12-14
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献Toward structural-omics of the bovine retinal pigment epithelium.
Cell Rep, 41, 2022
7U5M
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Cryo-EM Structure of GAPDH
分子名称: Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Morgan, C.E, Zhang, Z, Yu, E.W.
登録日2022-03-02
公開日2022-12-14
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.28 Å)
主引用文献Toward structural-omics of the bovine retinal pigment epithelium.
Cell Rep, 41, 2022
2W6F
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Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration: Hydration State 2.
分子名称: ATP SYNTHASE SUBUNIT ALPHA HEART ISOFORM, MITOCHONDRIAL, ATP SYNTHASE SUBUNIT BETA, ...
著者Sanchez-Weatherby, J, Felisaz, F, Gobbo, A, Huet, J, Ravelli, R.B.G, Bowler, M.W, Cipriani, F.
登録日2008-12-18
公開日2009-10-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (6 Å)
主引用文献Improving diffraction by humidity control: a novel device compatible with X-ray beamlines.
Acta Crystallogr. D Biol. Crystallogr., 65, 2009

224004

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