3VD2
 
 | | structure of p73 DNA binding domain tetramer modulates p73 transactivation | | 分子名称: | DNA (5'-D(*AP*TP*GP*GP*AP*CP*AP*TP*GP*TP*CP*CP*AP*T)-3'), Tumor protein p73, ZINC ION | | 著者 | Ethayathulla, A.S, Tse, P.W, Nguyen, S, Viadiu, H. | | 登録日 | 2012-01-04 | | 公開日 | 2012-04-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Structure of p73 DNA-binding domain tetramer modulates p73 transactivation.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3VDD
 | | Structure of HRV2 capsid complexed with antiviral compound BTA798 | | 分子名称: | 3-ethoxy-6-{2-[1-(6-methylpyridazin-3-yl)piperidin-4-yl]ethoxy}-1,2-benzoxazole, Protein VP1, Protein VP2, ... | | 著者 | Morton, C.J, Feil, S.C, Parker, M.W. | | 登録日 | 2012-01-05 | | 公開日 | 2012-09-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | An Orally Available 3-Ethoxybenzisoxazole Capsid Binder with Clinical Activity against Human Rhinovirus.
ACS Med Chem Lett, 3, 2012
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7D1X
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3VW5
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3VLU
 | | Crystal structure of Sphingomonas sp. A1 alginate-binding protein AlgQ1 in complex with saturated trimannuronate | | 分子名称: | AlgQ1, CALCIUM ION, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid | | 著者 | Nishitani, Y, Maruyama, Y, Itoh, T, Mikami, B, Hashimoto, W, Murata, K. | | 登録日 | 2011-12-05 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Recognition of heteropolysaccharide alginate by periplasmic solute-binding proteins of a bacterial ABC transporter
Biochemistry, 51, 2012
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3VQ9
 | | HIV-1 IN core domain in complex with 6-fluoro-1,3-benzothiazol-2-amine | | 分子名称: | 6-fluoro-1,3-benzothiazol-2-amine, POL polyprotein | | 著者 | Wielens, J, Chalmers, D.K, Parker, M.W, Scanlon, M.J. | | 登録日 | 2012-03-20 | | 公開日 | 2013-01-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?
J Biomol Screen, 18, 2013
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3VQP
 | | HIV-1 IN core domain in complex with 2,3-dihydro-1,4-benzodioxin-5-ylmethanol | | 分子名称: | 2,3-dihydro-1,4-benzodioxin-5-ylmethanol, CADMIUM ION, CHLORIDE ION, ... | | 著者 | Wielens, J, Chalmers, D.K, Parker, M.W, Scanlon, M.J. | | 登録日 | 2012-03-29 | | 公開日 | 2013-01-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?
J Biomol Screen, 18, 2013
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6LVP
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6LTR
 | | Crystal structure of Cas12i2 ternary complex with single Mg2+ bound in catalytic pocket | | 分子名称: | 1,2-ETHANEDIOL, Cas12i2, DNA (35-MER), ... | | 著者 | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | | 登録日 | 2020-01-23 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2.
Nat Commun, 11, 2020
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6LU0
 | | Crystal structure of Cas12i2 ternary complex with 12 nt spacer | | 分子名称: | Cas12i2, DNA (5'-D(*GP*CP*CP*GP*CP*TP*TP*TP*CP*TP*T)-3'), DNA (5'-D(*GP*CP*TP*TP*GP*CP*TP*CP*TP*GP*TP*TP*GP*AP*AP*AP*GP*CP*GP*GP*C)-3'), ... | | 著者 | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | | 登録日 | 2020-01-24 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | | 主引用文献 | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2.
Nat Commun, 11, 2020
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6LXE
 | | DROSHA-DGCR8 complex | | 分子名称: | Microprocessor complex subunit DGCR8, Ribonuclease 3, ZINC ION | | 著者 | Jin, W, Wang, J, Liu, C.P, Wang, H.W, Xu, R.M. | | 登録日 | 2020-02-10 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural Basis for pri-miRNA Recognition by Drosha.
Mol.Cell, 78, 2020
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3CFD
 | | Purple-fluorescent antibody EP2-25C10 in complex with its stilbene hapten | | 分子名称: | 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID, GLYCEROL, PURPLE-FLUORESCENT ANTIBODY EP2-25C10-IGG2B HEAVY CHAIN, ... | | 著者 | Debler, E.W, Heine, A, Wilson, I.A. | | 登録日 | 2008-03-03 | | 公開日 | 2008-03-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
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3CP6
 | | Crystal structure of human farnesyl diphosphate synthase (T201A mutant) complexed with Mg and biphosphonate inhibitor | | 分子名称: | (4aS,7aR)-octahydro-1H-cyclopenta[b]pyridine-6,6-diylbis(phosphonic acid), Farnesyl pyrophosphate synthetase, MAGNESIUM ION | | 著者 | Pilka, E.S, Dunford, J.E, Guo, K, Pike, A.C.W, von Delft, F, Barnett, B.L, Ebetino, F.H, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Russell, R.G.G, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2008-03-31 | | 公開日 | 2008-04-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Human farnesyl diphosphate synthase (T201A mutant) complexed with Mg and biphosphonate inhibitor.
To be Published
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3CPM
 | | plant peptide deformylase PDF1B crystal structure | | 分子名称: | Peptide deformylase, chloroplast, SULFATE ION, ... | | 著者 | Rodgers, D.W, Houtz, R.L, Dirk, L.M.A, Schmidt, J.J, Cai, Y. | | 登録日 | 2008-03-31 | | 公開日 | 2008-07-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Insights into the substrate specificity of plant peptide deformylase, an essential enzyme with potential for the development of novel biotechnology applications in agriculture
Biochem.J., 413, 2008
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4PHT
 | | ATPase GspE in complex with the cytoplasmic domain of GspL from the Vibrio vulnificus type II Secretion system | | 分子名称: | General secretory pathway protein E, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Lu, C, Korotkov, K, Hol, W. | | 登録日 | 2014-05-06 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | | 主引用文献 | Crystal structure of the full-length ATPase GspE from the Vibrio vulnificus type II secretion system in complex with the cytoplasmic domain of GspL.
J.Struct.Biol., 187, 2014
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3CJW
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3CWW
 | | Crystal Structure of IDE-bradykinin complex | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, ACETATE ION, Insulin-degrading enzyme, ... | | 著者 | Malito, E, Tang, W.J. | | 登録日 | 2008-04-23 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Molecular Bases for the Recognition of Short Peptide Substrates and Cysteine-Directed Modifications of Human Insulin-Degrading Enzyme
Biochemistry, 47, 2008
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3CY3
 | | Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and the JNK inhibitor V | | 分子名称: | (2S)-1,3-benzothiazol-2-yl{2-[(2-pyridin-3-ylethyl)amino]pyrimidin-4-yl}ethanenitrile, 1,2-ETHANEDIOL, Pimtide peptide, ... | | 著者 | Filippakopoulos, P, Bullock, A, Fedorov, O, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2008-04-25 | | 公開日 | 2008-07-15 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and the JNK inhibitor V.
To be Published
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3LCC
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3CFC
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4PIN
 | | Ergothioneine-biosynthetic methyltransferase EgtD in complex with N,N-dimethylhistidine | | 分子名称: | Histidine-specific methyltransferase EgtD, N,N-dimethyl-L-histidine, PHOSPHATE ION | | 著者 | Vit, A, Seebeck, F.P, Blankenfeldt, W. | | 登録日 | 2014-05-09 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Ergothioneine Biosynthetic Methyltransferase EgtD Reveals the Structural Basis of Aromatic Amino Acid Betaine Biosynthesis.
Chembiochem, 16, 2015
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3D6U
 | | Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase | | 分子名称: | 4-[3-(TRIFLUOROMETHYL)DIAZIRIDIN-3-YL]-L-PHENYLALANINE, BETA-MERCAPTOETHANOL, Tyrosyl-tRNA synthetase | | 著者 | Liu, W, Tippmann, E, Mack, A.V, Schultz, P.G. | | 登録日 | 2008-05-20 | | 公開日 | 2008-05-27 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A genetically encoded diazirine photocrosslinker in Escherichia coli
ChemBioChem, 8, 2007
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3CFB
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4PE3
 | | CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM RHODOBACTER SPHAEROIDES (Rsph17029_3620, TARGET EFI-510199), APO OPEN STRUCTURE | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, IMIDAZOLE, ... | | 著者 | Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2014-04-22 | | 公開日 | 2014-05-14 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.
Biochemistry, 54, 2015
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2FTE
 | | Bacteriophage HK97 Expansion Intermediate IV | | 分子名称: | major capsid protein | | 著者 | Gan, L, Speir, J.A, Conway, J.F, Lander, G, Cheng, N, Firek, B.A, Hendrix, R.W, Duda, R.L, Liljas, L, Johnson, J.E. | | 登録日 | 2006-01-24 | | 公開日 | 2006-02-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY | | 主引用文献 | Capsid Conformational Sampling in HK97 Maturation Visualized by X-Ray Crystallography and Cryo-EM.
Structure, 14, 2006
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