1UMX
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![BU of 1umx by Molmil](/molmil-images/mine/1umx) | PHOTOSYNTHETIC REACTION CENTER MUTANT WITH ARG M267 REPLACED WITH LEU (CHAIN M, R267L) | 分子名称: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN B, FE (III) ION, ... | 著者 | Fyfe, P.K, Isaacs, N.W, Cogdell, R.J, Jones, M.R. | 登録日 | 2003-09-02 | 公開日 | 2004-06-29 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Disruption of a specific molecular interaction with a bound lipid affects the thermal stability of the purple bacterial reaction centre. Biochim.Biophys.Acta, 1608, 2004
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1QS5
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1QSB
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1Q6T
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![BU of 1q6t by Molmil](/molmil-images/mine/1q6t) | THE STRUCTURE OF PHOSPHOTYROSINE PHOSPHATASE 1B IN COMPLEX WITH COMPOUND 11 | 分子名称: | 6-[4-((2S)-2-(1H-1,2,3-BENZOTRIAZOL-1-YL)-3-{4-[DIFLUORO(PHOSPHONO)METHYL]PHENYL}-2-PHENYLPROPYL)PHENYL]-2-[(1S)-1-METHOXY-3-METHYLBUTYL]QUINOLIN-8-YLPHOSPHONIC ACID, MAGNESIUM ION, Protein-tyrosine phosphatase, ... | 著者 | Scapin, G, Patel, S.B, Becker, J.W, Wang, Q, Desponts, C, Waddleton, D, Skorey, K, Cromlish, W, Bayly, C, Therien, M, Gauthier, J.Y, Li, C.S, Lau, C.K, Ramachandran, C, Kennedy, B.P, Asante-Appiah, E. | 登録日 | 2003-08-13 | 公開日 | 2003-09-30 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Structural Basis for the Selectivity of Benzotriazole Inhibitors of Ptp1B Biochemistry, 42, 2003
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1QF4
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![BU of 1qf4 by Molmil](/molmil-images/mine/1qf4) | DESIGN, SYNTHESIS, AND X-RAY CRYSTAL STRUCTURE OF AN ENZYME BOUND BISUBSTRATE HYBRID INHIBITOR OF ADENYLOSUCCINATE SYNTHETASE | 分子名称: | (C8-R)-HYDANTOCIDIN 5'-PHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Hanessian, S, Lu, P.-P, Sanceau, J.-Y, Chemla, P, Gohda, K, Fonne-Pfister, R, Prade, L, Cowan-Jacob, S.W. | 登録日 | 1999-04-06 | 公開日 | 1999-12-02 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | An enzyme-bound bisubstrate hybrid inhibitor of adenylosuccinate synthetase Angew.Chem.Int.Ed.Engl., 38, 1999
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1QJJ
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1Q6N
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![BU of 1q6n by Molmil](/molmil-images/mine/1q6n) | THE STRUCTURE OF PHOSPHOTYROSINE PHOSPHATASE 1B IN COMPLEX WITH COMPOUND 4 | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Protein-tyrosine phosphatase, ... | 著者 | Scapin, G, Patel, S.B, Becker, J.W, Wang, Q, Desponts, C, Waddleton, D, Skorey, K, Cromlish, W, Bayly, C, Therien, M, Gauthier, J.Y, Li, C.S, Lau, C.K, Ramachandran, C, Kennedy, B.P, Asante-Appiah, E. | 登録日 | 2003-08-13 | 公開日 | 2003-09-30 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Structural Basis for the Selectivity of Benzotriazole Inhibitors of Ptp1B Biochemistry, 42, 2003
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1QTC
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1T8G
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![BU of 1t8g by Molmil](/molmil-images/mine/1t8g) | Crystal structure of phage T4 lysozyme mutant L32A/L33A/T34A/C54T/C97A/E108V | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme, ... | 著者 | He, M.M, Wood, Z.A, Baase, W.A, Xiao, H, Matthews, B.W. | 登録日 | 2004-05-12 | 公開日 | 2004-10-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation. Protein Sci., 13, 2004
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1TH1
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![BU of 1th1 by Molmil](/molmil-images/mine/1th1) | Beta-catenin in complex with a phosphorylated APC 20aa repeat fragment | 分子名称: | Adenomatous polyposis coli protein, Beta-catenin | 著者 | Xing, Y, Clements, W.K, Le Trong, I, Hinds, T.R, Stenkamp, R, Kimelman, D, Xu, W. | 登録日 | 2004-05-31 | 公開日 | 2004-09-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of a beta-Catenin/APC Complex Reveals a Critical Role for APC Phosphorylation in APC Function. Mol.Cell, 15, 2004
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1TIY
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![BU of 1tiy by Molmil](/molmil-images/mine/1tiy) | X-RAY STRUCTURE OF GUANINE DEAMINASE FROM BACILLUS SUBTILIS NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR160 | 分子名称: | Guanine deaminase, ZINC ION | 著者 | Kuzin, A.P, Vorobiev, S, Edstrom, W, Forouhar, F, Acton, T, Shastry, R, Ma, L.-C, Chiang, Y.-W, Montelione, G, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2004-06-02 | 公開日 | 2004-06-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | X-RAY STRUCTURE OF GUANINE DEAMINASE FROM BACILLUS SUBTILIS
NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR160 To be published
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1L0H
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![BU of 1l0h by Molmil](/molmil-images/mine/1l0h) | CRYSTAL STRUCTURE OF BUTYRYL-ACP FROM E.COLI | 分子名称: | ACYL CARRIER PROTEIN, ZINC ION | 著者 | Roujeinikova, A, Baldock, C, Simon, W.J, Gilroy, J, Baker, P.J, Stuitje, A.R, Rice, D.W, Slabas, A.R, Rafferty, J.B. | 登録日 | 2002-02-11 | 公開日 | 2003-02-11 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray crystallographic studies on butyryl-ACP reveal flexibility of the structure around a putative acyl chain binding site Structure, 10, 2002
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1S4Y
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![BU of 1s4y by Molmil](/molmil-images/mine/1s4y) | Crystal structure of the activin/actrIIb extracellular domain | 分子名称: | Activin receptor type IIB precursor, Inhibin beta A chain | 著者 | Greenwald, J, Vega, M.E, Allendorph, G.P, Fischer, W.H, Vale, W, Choe, S, Joint Center for Structural Genomics (JCSG) | 登録日 | 2004-01-19 | 公開日 | 2004-08-10 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A Flexible Activin Explains the Membrane-Dependent Cooperative Assembly of TGF-beta Family Receptors. Mol.Cell, 15, 2004
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1LRW
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![BU of 1lrw by Molmil](/molmil-images/mine/1lrw) | Crystal structure of methanol dehydrogenase from P. denitrificans | 分子名称: | CALCIUM ION, PYRROLOQUINOLINE QUINONE, methanol dehydrogenase subunit 1, ... | 著者 | Xia, Z.-X, Dai, W.-W, He, Y.-N, White, S.A, Mathews, F.S, Davidson, V.L. | 登録日 | 2002-05-16 | 公開日 | 2003-08-12 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | X-ray structure of methanol dehydrogenase from Paracoccus denitrificans and molecular modeling of its interactions with cytochrome c-551i J.Biol.Inorg.Chem., 8, 2003
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1SQO
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![BU of 1sqo by Molmil](/molmil-images/mine/1sqo) | Substituted 2-Naphthamidine Inhibitors of Urokinase | 分子名称: | 8-(PYRIMIDIN-2-YLAMINO)NAPHTHALENE-2-CARBOXIMIDAMIDE, SULFATE ION, Urokinase-type plasminogen activator | 著者 | Wendt, M.D, Geyer, A, McClellan, W.J, Rockway, T.W, Weitzberg, M, Zhao, X, Mantei, R, Stewart, K, Nienaber, V, Klinghofer, V, Giranda, V.L. | 登録日 | 2004-03-19 | 公開日 | 2004-04-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Interaction with the S1beta-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors. Bioorg.Med.Chem.Lett., 14, 2004
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1SOI
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![BU of 1soi by Molmil](/molmil-images/mine/1soi) | CRYSTAL STRUCTURE OF NUDIX HYDROLASE DR1025 IN COMPLEX WITH SM+3 | 分子名称: | MutT/nudix family protein, SAMARIUM (III) ION | 著者 | Ranatunga, W, Hill, E.E, Mooster, J.L, Holbrook, E.L, Schulze-Gahmen, U, Xu, W, Bessman, M.J, Brenner, S.E, Holbrook, S.R, Berkeley Structural Genomics Center (BSGC) | 登録日 | 2004-03-15 | 公開日 | 2004-05-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Studies of the Nudix Hydrolase DR1025 From Deinococcus radiodurans and its Ligand Complexes. J.Mol.Biol., 339, 2004
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2HXT
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![BU of 2hxt by Molmil](/molmil-images/mine/2hxt) | Crystal structure of L-Fuconate Dehydratase from Xanthomonas campestris liganded with Mg++ and D-erythronohydroxamate | 分子名称: | (2R,3R)-N,2,3,4-TETRAHYDROXYBUTANAMIDE, L-fuconate dehydratase, MAGNESIUM ION | 著者 | Fedorov, A.A, Fedorov, E.V, Yew, W.S, Rakus, J.F, Gerlt, J.A, Almo, S.C. | 登録日 | 2006-08-03 | 公開日 | 2006-12-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Evolution of Enzymatic Activities in the Enolase Superfamily: l-Fuconate Dehydratase from Xanthomonas campestris. Biochemistry, 45, 2006
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1SQA
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![BU of 1sqa by Molmil](/molmil-images/mine/1sqa) | Substituted 2-Naphthamidine Inhibitors of Urokinase | 分子名称: | 6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENYL]-4-(PYRIMIDIN-2-YLAMINO)-2-NAPHTHAMIDE, SULFATE ION, Urokinase-type plasminogen activator | 著者 | Wendt, M.D, Geyer, A, McClellan, W.J, Rockway, T.W, Weitzberg, M, Zhao, X, Stewart, K, Nienaber, V, Klinghofer, V, Giranda, V.L. | 登録日 | 2004-03-18 | 公開日 | 2004-04-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Interaction with the S1beta-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors. Bioorg.Med.Chem.Lett., 14, 2004
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2HZN
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![BU of 2hzn by Molmil](/molmil-images/mine/2hzn) | Abl kinase domain in complex with NVP-AFG210 | 分子名称: | 1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA, Proto-oncogene tyrosine-protein kinase ABL1 | 著者 | Cowan-Jacob, S.W, Fendrich, G, Liebetanz, J, Fabbro, D, Manley, P. | 登録日 | 2006-08-09 | 公開日 | 2007-01-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia. ACTA CRYSTALLOGR.,SECT.D, 63, 2007
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1HAF
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1HAE
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1SMO
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![BU of 1smo by Molmil](/molmil-images/mine/1smo) | Crystal Structure of Human Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) at 1.47 . | 分子名称: | L(+)-TARTARIC ACID, triggering receptor expressed on myeloid cells 1 | 著者 | Kelker, M.S, Foss, T.R, Peti, W, Teyton, L, Kelly, J.W, Wilson, I.A. | 登録日 | 2004-03-09 | 公開日 | 2004-09-21 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Crystal Structure of Human Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) at 1.47A. J.Mol.Biol., 342, 2004
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1SOL
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![BU of 1sol by Molmil](/molmil-images/mine/1sol) | A PIP2 AND F-ACTIN-BINDING SITE OF GELSOLIN, RESIDUE 150-169 (NMR, AVERAGED STRUCTURE) | 分子名称: | GELSOLIN (150-169) | 著者 | Xian, W, Vegners, R, Janmey, P.A, Braunlin, W.H. | 登録日 | 1995-09-29 | 公開日 | 1996-03-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Spectroscopic studies of a phosphoinositide-binding peptide from gelsolin: behavior in solutions of mixed solvent and anionic micelles. Biophys.J., 69, 1995
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1VCX
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![BU of 1vcx by Molmil](/molmil-images/mine/1vcx) | Neutron Crystal Structure of the Wild Type Rubredoxin from Pyrococcus Furiosus at 1.5A Resolution | 分子名称: | FE (III) ION, Rubredoxin | 著者 | Kurihara, K, Tanaka, I, Chatake, T, Adams, M.W.W, Jenney Jr, F.E, Moiseeva, N, Bau, R, Niimura, N. | 登録日 | 2004-03-17 | 公開日 | 2004-08-10 | 最終更新日 | 2023-10-25 | 実験手法 | NEUTRON DIFFRACTION (1.5 Å) | 主引用文献 | Neutron crystallographic study on rubredoxin from Pyrococcus furiosus by BIX-3, a single-crystal diffractometer for biomacromolecules Proc.Natl.Acad.Sci.USA, 101, 2004
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2GC0
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