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PDB: 72 件
2QZ9
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crystal structure of aspartate semialdehyde dehydrogenase II from vibrio cholerae
分子名称: Aspartate-semialdehyde dehydrogenase
著者Viola, R.E, Liu, X, Ohren, J.F, Faehnle, C.R.
登録日2007-08-16
公開日2008-04-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae.
Acta Crystallogr.,Sect.D, 64, 2008
2R00
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crystal structure of aspartate semialdehyde dehydrogenase II complexed with ASA from vibrio cholerae
分子名称: 2,2'-oxydiacetic acid, Aspartate-semialdehyde dehydrogenase
著者Viola, R.E, Liu, X, Ohren, J.F, Faehnle, C.R.
登録日2007-08-17
公開日2008-04-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae.
Acta Crystallogr.,Sect.D, 64, 2008
1TB4
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Crystal Structure of Aspartate-Semialdehyde Dehydrogenase From Haemophilus influenzae with a Bound Periodate
分子名称: Aspartate-semialdehyde dehydrogenase, PERIODATE
著者Viola, R.E.
登録日2004-05-19
公開日2004-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis for discrimination between oxyanion substrates or inhibitors in aspartate-beta-semialdehyde dehydrogenase.
Acta Crystallogr.,Sect.D, 60, 2004
1TA4
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Crystal Structure Of Aspartate-Semialdehyde Dehydrogenase From Haemophilus Influenzae with a Bound Arsenate
分子名称: ARSENATE, Aspartate-semialdehyde dehydrogenase
著者Viola, R.E.
登録日2004-05-19
公開日2004-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structural basis for discrimination between oxyanion substrates or inhibitors in aspartate-beta-semialdehyde dehydrogenase.
Acta Crystallogr.,Sect.D, 60, 2004
3C20
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BU of 3c20 by Molmil
Crystal Structure of Threonine-sensitive Aspartokinase from Methanococcus jannaschii with L-aspartate
分子名称: ASPARTIC ACID, FORMIC ACID, Probable aspartokinase
著者Liu, X, Pavlovsky, A.G, Viola, R.E.
登録日2008-01-24
公開日2008-04-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Structural Basis for Allosteric Inhibition of a Threonine-sensitive Aspartokinase.
J.Biol.Chem., 283, 2008
5JW6
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BU of 5jw6 by Molmil
Cystal structure of aspartate semialdehyde dehydrogenase from Aspergillus fumigatus
分子名称: Aspartate-semialdehyde dehydrogenase, SULFATE ION
著者Dahal, G.P, Viola, R.E.
登録日2016-05-11
公開日2017-01-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structure of a fungal form of aspartate-semialdehyde dehydrogenase from Aspergillus fumigatus.
Acta Crystallogr F Struct Biol Commun, 73, 2017
1BRM
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ASPARTATE BETA-SEMIALDEHYDE DEHYDROGENASE FROM ESCHERICHIA COLI
分子名称: ASPARTATE-SEMIALDEHYDE DEHYDROGENASE
著者Hadfield, A.T, Kryger, G, Ouyang, J, Ringe, D, Petsko, G.A, Viola, R.E.
登録日1998-08-24
公開日1999-06-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of aspartate-beta-semialdehyde dehydrogenase from Escherichia coli, a key enzyme in the aspartate family of amino acid biosynthesis.
J.Mol.Biol., 289, 1999
4MXU
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Human brain aspartoacylase mutant K213E complex with intermediate analog (N-phosphonomethyl-L-aspartate)
分子名称: Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION
著者Wijayasinghe, Y.S, Pavlovsky, A.G, Viola, R.E.
登録日2013-09-26
公開日2014-07-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Aspartoacylase catalytic deficiency as the cause of canavan disease: a structural perspective.
Biochemistry, 53, 2014
4MRI
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Human brain aspartoacylase mutant F295S complex with intermediate analog (N-phosphonomethyl-L-aspartate)
分子名称: Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION
著者Wijayasinghe, Y.S, Pavlovsky, A.G, Viola, R.E.
登録日2013-09-17
公開日2014-07-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Aspartoacylase catalytic deficiency as the cause of canavan disease: a structural perspective.
Biochemistry, 53, 2014
4LE5
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Structure of an Unusual S-adenosylmethionine synthetase from Campylobacter jejuni
分子名称: S-adenosylmethionine synthetase
著者Zano, S.P, Pavlovsky, A.G, Viola, R.E.
登録日2013-06-25
公開日2014-02-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of an unusual S-adenosylmethionine synthetase from Campylobacter jejuni.
Acta Crystallogr.,Sect.D, 70, 2014
2YXP
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BU of 2yxp by Molmil
The Effect of Deuteration on Protein Structure A High Resolution Comparison of Hydrogenous and Perdeuterated Haloalkane Dehalogenase
分子名称: Haloalkane dehalogenase
著者Liu, X, Hanson, L, Langan, P, Viola, R.E.
登録日2007-04-27
公開日2007-09-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献The effect of deuteration on protein structure: a high-resolution comparison of hydrogenous and perdeuterated haloalkane dehalogenase.
Acta Crystallogr.,Sect.D, 63, 2007
4R5M
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BU of 4r5m by Molmil
Crystal structure of Vc-Aspartate beta-semialdehyde-dehydrogenase with NADP and 4-Nitro-2-Phosphono-Benzoic acid
分子名称: 4-nitro-2-phosphonobenzoic acid, Aspartate-semialdehyde dehydrogenase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Pavlovsky, A.G, Thangavelu, B, Bhansali, P, Viola, R.E.
登録日2014-08-21
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway.
Acta Crystallogr.,Sect.D, 70, 2014
4R54
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Complex crystal structure of sp-Aspartate-Semialdehyde-Dehydrogenase with 3-carboxy-ethyl-phthalic acid
分子名称: 3-(2-carboxyethyl)benzene-1,2-dicarboxylic acid, ACETATE ION, Aspartate-semialdehyde dehydrogenase, ...
著者Pavlovsky, A.G, Viola, R.E.
登録日2014-08-20
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway.
Acta Crystallogr.,Sect.D, 70, 2014
4TNU
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Human brain aspartoacylase mutant Y231C complex with intermediate analog (N-phosphonomethyl-L-aspartate)
分子名称: Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION
著者Wijayasinghe, Y.S, Pavlovsky, A.G, Viola, R.E.
登録日2014-06-05
公開日2014-07-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Aspartoacylase catalytic deficiency as the cause of canavan disease: a structural perspective.
Biochemistry, 53, 2014
6C07
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BU of 6c07 by Molmil
Crystal Structure of S-Adenosylmethionine synthetase (MetK/Mat) from Cryptosporidium parvum
分子名称: CHLORIDE ION, MAGNESIUM ION, POTASSIUM ION, ...
著者Ohren, J.F, Viola, R.E.
登録日2017-12-28
公開日2019-01-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of a critical metabolic enzyme: S-adenosylmethionine synthetase from Cryptosporidium parvum.
Acta Crystallogr F Struct Biol Commun, 75, 2019
6C8W
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Crystal structure of Aspartate Semialdehyde Dehydrogenase with NADP from Blastomyces dermatitidis
分子名称: Aspartate-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Dahal, G.P, Viola, R.E.
登録日2018-01-25
公開日2019-01-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into inhibitor binding to a fungal ortholog of aspartate semialdehyde dehydrogenase.
Biochem.Biophys.Res.Commun., 503, 2018
6C85
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Crystal structure of aspartate semialdehyde dehydrogenase from Blastomyces dermatitidis with p-benzoquinone
分子名称: 1,4-benzoquinone, Aspartate-semialdehyde dehydrogenase
著者Dahal, G.P, Viola, R.E.
登録日2018-01-24
公開日2019-01-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights into inhibitor binding to a fungal ortholog of aspartate semialdehyde dehydrogenase.
Biochem.Biophys.Res.Commun., 503, 2018
5CEF
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Cystal structure of aspartate semialdehyde dehydrogenase from Cryptococcus neoformans
分子名称: 1,2-ETHANEDIOL, Aspartate-semialdehyde dehydrogenase
著者Dahal, G.P, Viola, R.E.
登録日2015-07-06
公開日2015-11-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of a fungal form of aspartate semialdehyde dehydrogenase from Cryptococcus neoformans.
Acta Crystallogr.,Sect.F, 71, 2015
1GL3
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ASPARTATE BETA-SEMIALDEHYDE DEHYDROGENASE IN COMPLEX WITH NADP AND SUBSTRATE ANALOGUE S-METHYL CYSTEINE SULFOXIDE
分子名称: ASPARTATE-SEMIALDEHYDE DEHYDROGENASE, CYSTEINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Hadfield, A.T, Kryger, G, Ouyang, J, Ringe, D, Petsko, G.A, Viola, R.E.
登録日2001-08-23
公開日2001-11-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Active Site Analysis of the Potential Antimicrobial Target Aspartate Semialdehyde Dehydrogenase.
Biochemistry, 40, 2001
3HSK
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Crystal Structure of Aspartate Semialdehyde Dehydrogenase with NADP from Candida albicans
分子名称: Aspartate-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Arachea, B.T, Pavlovsky, A, Liu, X, Viola, R.E.
登録日2009-06-10
公開日2010-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Expansion of the aspartate beta-semialdehyde dehydrogenase family: the first structure of a fungal ortholog.
Acta Crystallogr.,Sect.D, 66, 2010
4QLO
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BU of 4qlo by Molmil
Crystal Structure of homoserine o-acetyltransferase from Staphylococcus aureus
分子名称: homoserine O-acetyltransferase
著者Thangavelu, B, Pavlovsky, A.G, Viola, R.E.
登録日2014-06-12
公開日2014-08-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure of homoserine O-acetyltransferase from Staphylococcus aureus: the first Gram-positive ortholog structure.
Acta Crystallogr.,Sect.F, 70, 2014
4NFR
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BU of 4nfr by Molmil
Human brain aspartoacylase mutant E285A complex with intermediate analog (N-phosphonomethyl-L-aspartate)
分子名称: Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION
著者Wijayasinghe, Y.S, Pavlovsky, A.G, Viola, R.E.
登録日2013-10-31
公開日2014-07-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Aspartoacylase catalytic deficiency as the cause of canavan disease: a structural perspective.
Biochemistry, 53, 2014
4R41
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Complex Crystal structure of 4-nitro-2-phosphono-benzoic acid with sp-Aspartate-Semialdehyde Dehydrogenase and Nicotinamide-dinucleotide
分子名称: 1,2-ETHANEDIOL, 4-nitro-2-phosphonobenzoic acid, ACETATE ION, ...
著者Pavlovsky, A.G, Viola, R.E.
登録日2014-08-18
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway.
Acta Crystallogr.,Sect.D, 70, 2014
4R4J
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Crystal structure of complex sp_ASADH with 3-carboxypropyl-phthalic acid and Nicotinamide Adenine dinucleotide phosphate
分子名称: 1,2-ETHANEDIOL, 3-(3-carboxypropyl)benzene-1,2-dicarboxylic acid, Aspartate-semialdehyde dehydrogenase, ...
著者Pavlovsky, A.G, Thangavelu, B, Bhansali, P, Viola, R.E.
登録日2014-08-19
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway.
Acta Crystallogr.,Sect.D, 70, 2014
4R51
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Crystal complex structure of sp-Aspartate-Semialdehyde-Dehydrogenase with Nicotinamide Adenine dinucleotide phosphate and phthalic acid
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Aspartate-semialdehyde dehydrogenase, ...
著者Pavlovsky, A.G, Viola, R.E.
登録日2014-08-20
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway.
Acta Crystallogr.,Sect.D, 70, 2014

 

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