6C85

Crystal structure of aspartate semialdehyde dehydrogenase from Blastomyces dermatitidis with p-benzoquinone

Summary for 6C85

Entry DOI	10.2210/pdb6c85/pdb
Descriptor	Aspartate-semialdehyde dehydrogenase, 1,4-benzoquinone (3 entities in total)
Functional Keywords	rossman fold, oxidoreductase, antifungal inhibitor complex
Biological source	Blastomyces gilchristii (Blastomyces dermatitidis)
Total number of polymer chains	2
Total formula weight	80522.14
Authors	Dahal, G.P.,Viola, R.E. (deposition date: 2018-01-24, release date: 2019-01-30, Last modification date: 2023-10-04)
Primary citation	Dahal, G.P.,Viola, R.E. Structural insights into inhibitor binding to a fungal ortholog of aspartate semialdehyde dehydrogenase. Biochem.Biophys.Res.Commun., 503:2848-2854, 2018 Cited by PubMed: 30107909 DOI: 10.1016/j.bbrc.2018.08.053 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation