1SYL
| Crystal structure of inactive mutant dUTPase complexed with substrate dUTP | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DEOXYURIDINE-5'-TRIPHOSPHATE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | 著者 | Barabas, O, Kovari, J, Pongracz, V, Wilmanns, M, Vertessy, B.G. | 登録日 | 2004-04-01 | 公開日 | 2004-09-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase J.Biol.Chem., 279, 2004
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3TQ5
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2PY4
| Full length structure of the Mycobacterium tuberculosis dUTPase complexed with magnesium and alpha,beta-imido-dUTP. | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | 著者 | Barabas, O, Nagy, N, Takacs, E, Vertessy, B.G. | 登録日 | 2007-05-15 | 公開日 | 2007-05-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor. Biochem.Biophys.Res.Commun., 373, 2008
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2HQU
| Human dUTPase in complex with alpha,beta-iminodUTP and magnesium ion | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | 著者 | Barabas, O, Varga, B, Vertessy, B.G. | 登録日 | 2006-07-19 | 公開日 | 2007-07-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase. Febs Lett., 581, 2007
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1RNJ
| Crystal structure of inactive mutant dUTPase complexed with substrate analogue imido-dUTP | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | 著者 | Barabas, O, Pongracz, V, Kovari, J, Wilmanns, M, Vertessy, B.G. | 登録日 | 2003-12-01 | 公開日 | 2004-09-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase. J.Biol.Chem., 279, 2004
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3IF7
| Structure of Calmodulin complexed with its first endogenous inhibitor, sphingosylphosphorylcholine | 分子名称: | 2-{[(R)-{[(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}(hydroxy)phosphoryl]oxy}-N,N,N-trimethylethanaminium, CALCIUM ION, Calmodulin | 著者 | Kovacs, E, Harmat, V, Toth, J, Vertessy, B.G, Modos, K, Kardos, J, Liliom, K. | 登録日 | 2009-07-24 | 公開日 | 2010-06-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure and mechanism of calmodulin binding to a signaling sphingolipid reveal new aspects of lipid-protein interactions Faseb J., 24, 2010
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3I93
| Crystal structure of Mycobacterium tuberculosis dUTPase STOP138T mutant | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | 著者 | Leveles, I, Harmat, V, Lopata, A, Toth, J, Vertessy, B.G. | 登録日 | 2009-07-10 | 公開日 | 2009-11-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases. Febs Lett., 584, 2010
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3HZA
| Crystal structure of dUTPase H145W mutant | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | 著者 | Leveles, I, Harmat, V, Pecsi, I, Toth, J, Vertessy, B.G. | 登録日 | 2009-06-23 | 公開日 | 2009-11-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase. Nucleic Acids Res., 38, 2010
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3H6D
| Structure of the mycobacterium tuberculosis DUTPase D28N mutant | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | 著者 | Leveles, I, Harmat, V, Nagy, G, Takacs, E, Lopata, A, Toth, J, Vertessy, B.G. | 登録日 | 2009-04-23 | 公開日 | 2009-11-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases. Febs Lett., 584, 2010
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