2XA3
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![BU of 2xa3 by Molmil](/molmil-images/mine/2xa3) | crystal structure of the broadly neutralizing llama VHH D7 and its mode of HIV-1 gp120 interaction | Descriptor: | LLAMA HEAVY CHAIN ANTIBODY D7, SULFATE ION | Authors: | Hinz, A, Lutje Hulsik, D, Forsman, A, Koh, W, Belrhali, H, Gorlani, A, de Haard, H, Weiss, R.A, Verrips, T, Weissenhorn, W. | Deposit date: | 2010-03-29 | Release date: | 2010-05-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of the neutralizing Llama V(HH) D7 and its mode of HIV-1 gp120 interaction. PLoS ONE, 5, 2010
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3RJQ
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![BU of 3rjq by Molmil](/molmil-images/mine/3rjq) | Crystal structure of anti-HIV llama VHH antibody A12 in complex with C186 gp120 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C186 gp120, Llama VHH A12 | Authors: | Chen, L, McLellan, J.S, Kwon, Y.D, Schmidt, S, Wu, X, Zhou, T, Yang, Y, Zhang, B, Forsman, A, Weiss, R.A, Verrips, T, Mascola, J, Kwong, P.D. | Deposit date: | 2011-04-15 | Release date: | 2012-05-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Crystal structure of anti-HIV A12 VHH of llama antibody in complex with C1086 gp120 To be Published
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3R0M
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![BU of 3r0m by Molmil](/molmil-images/mine/3r0m) | Crystal structure of anti-HIV llama VHH antibody A12 | Descriptor: | Llama VHH A12, SULFATE ION | Authors: | Chen, L, McLellan, J.S, Kwon, Y.D, Schmidt, S, Wu, X, Zhou, T, Yang, Y, Zhang, B, Forsman, A, Weiss, R.A, Verrips, T, Mascola, J, Kwong, P.D. | Deposit date: | 2011-03-08 | Release date: | 2012-03-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Single-Headed Immunoglobulins Efficiently Penetrate CD4-Binding Site and Effectively Neutralize HIV-1 To be Published
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1QD0
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![BU of 1qd0 by Molmil](/molmil-images/mine/1qd0) | CAMELID HEAVY CHAIN VARIABLE DOMAINS PROVIDE EFFICIENT COMBINING SITES TO HAPTENS | Descriptor: | 3-HYDROXY-7-(4-{1-[2-HYDROXY-3-(2-HYDROXY-5-SULFO-PHENYLAZO)-BENZYL]-2-SULFO-ETHYLAMINO}-[1,2,5]TRIAZIN-2-YLAMINO)-2-(2-HYDROXY-5-SULFO-PHENYLAZO)-NAPTHALENE-1,8-DISULFONIC ACID, COPPER (II) ION, VHH-R2 ANTI-RR6 ANTIBODY | Authors: | Spinelli, S, Frenken, L.G.J, Hermans, P, Verrips, T, Brown, K, Tegoni, M, Cambillau, C. | Deposit date: | 1999-07-08 | Release date: | 2000-07-19 | Last modified: | 2018-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Camelid heavy-chain variable domains provide efficient combining sites to haptens. Biochemistry, 39, 2000
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4R90
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![BU of 4r90 by Molmil](/molmil-images/mine/4r90) | Anti CD70 Llama glama Fab 27B3 | Descriptor: | Anti CD70 Llama glama Fab 27B3 Heavy chain, Anti CD70 Llama glama Fab 27B3 Light chain, CALCIUM ION, ... | Authors: | Klarenbeek, A, El Mazouari, K, Desmyter, A, Blanchetot, C, Hultberg, A, Roovers, R.C, Cambillau, C, Spinelli, S, Del-Favero, J, Verrips, T, de Haard, H, Achour, I. | Deposit date: | 2014-09-03 | Release date: | 2015-06-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.746 Å) | Cite: | Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform. MAbs, 7, 2015
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4R96
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![BU of 4r96 by Molmil](/molmil-images/mine/4r96) | Structure of a Llama Glama Fab 48A2 against human cMet | Descriptor: | Llama glama Fab 48A2 against human cMet H chain, Llama glama Fab 48A2 against human cMet L chain | Authors: | Klarenbeek, A, El Mazouari, K, Desmyter, A, Blanchetot, C, Hultberg, A, Roovers, R.C, Cambillau, C, Spinelli, S, Del-Favero, J, Verrips, T, de Haard, H, Achour, I. | Deposit date: | 2014-09-03 | Release date: | 2015-06-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform. MAbs, 7, 2015
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5O2U
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![BU of 5o2u by Molmil](/molmil-images/mine/5o2u) | Llama VHH in complex with p24 | Descriptor: | Capsid protein p24, VHH 59H10 | Authors: | Caillat, C, Verrips, T, Weissenhorn, W. | Deposit date: | 2017-05-22 | Release date: | 2017-06-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Unravelling the Molecular Basis of High Affinity Nanobodies against HIV p24: In Vitro Functional, Structural, and in Silico Insights. ACS Infect Dis, 3, 2017
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1SJV
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![BU of 1sjv by Molmil](/molmil-images/mine/1sjv) | Three-Dimensional Structure of a Llama VHH Domain Swapping | Descriptor: | r9 | Authors: | Spinelli, S, Desmyter, A, Frenken, L, Verrips, T, Cambillau, C. | Deposit date: | 2004-03-04 | Release date: | 2004-06-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Domain swapping of a llama VHH domain builds a crystal-wide beta-sheet structure. Febs Lett., 564, 2004
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1SJX
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![BU of 1sjx by Molmil](/molmil-images/mine/1sjx) | Three-Dimensional Structure of a Llama VHH Domain OE7 binding the cell wall protein Malf1 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, immunoglobulin VH domain | Authors: | Dolk, E, van der Vaart, M, Hulsik, D.L, Vriend, G, de Haard, H, Spinelli, S, Cambillau, C, Frenken, L, Verrips, T. | Deposit date: | 2004-03-04 | Release date: | 2005-03-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Isolation of llama antibody fragments for prevention of dandruff by phage display in shampoo. Appl.Environ.Microbiol., 71, 2005
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1U0Q
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![BU of 1u0q by Molmil](/molmil-images/mine/1u0q) | |