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PDB: 155 件

1MQ0
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Crystal Structure of Human Cytidine Deaminase
分子名称: 1-BETA-RIBOFURANOSYL-1,3-DIAZEPINONE, Cytidine Deaminase, ZINC ION
著者Chung, S.J, Fromme, J.C, Verdine, G.L.
登録日2002-09-13
公開日2003-11-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of human cytidine deaminase bound to a potent inhibitor
J.Med.Chem., 48, 2005
1N39
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Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase
分子名称: CALCIUM ION, DNA complement strand, DNA inhibitor strand, ...
著者Norman, D.P, Chung, S.J, Verdine, G.L.
登録日2002-10-25
公開日2003-03-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase
Biochemistry, 42, 2003
1MWJ
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Crystal Structure of a MUG-DNA pseudo substrate complex
分子名称: 5'-D(*CP*GP*CP*GP*A*GP*(DU)P*TP*CP*GP*CP*G)-3', G/U mismatch-specific DNA glycosylase
著者Barrett, T.E, Scharer, O, Savva, R, Brown, T, Jiricny, J, Verdine, G.L, Pearl, L.H.
登録日2002-09-30
公開日2002-10-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal Structure of a thwarted mismatch glycosylase DNA repair complex
Embo J., 18, 1999
1N3A
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Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase
分子名称: CALCIUM ION, DNA complement strand, DNA inhibitor strand, ...
著者Norman, D.P, Chung, S.J, Verdine, G.L.
登録日2002-10-25
公開日2003-03-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase
Biochemistry, 42, 2003
1N3C
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Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase
分子名称: 8-oxoG-containing DNA, CALCIUM ION, DNA complement strand, ...
著者Norman, D.P, Chung, S.J, Verdine, G.L.
登録日2002-10-25
公開日2003-03-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase
Biochemistry, 42, 2003
1HU0
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CRYSTAL STRUCTURE OF AN HOGG1-DNA BOROHYDRIDE TRAPPED INTERMEDIATE COMPLEX
分子名称: 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-OXOGUANINE, ...
著者Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L.
登録日2001-01-03
公開日2003-02-25
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Product-Assisted Catalysis in base-excision DNA Repair
Nat.Struct.Biol., 10, 2003
3OH6
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AlkA Undamaged DNA Complex: Interrogation of a C:G base pair
分子名称: 5'-D(*GP*AP*CP*AP*(BRU)P*GP*AP*AP*(BRU)P*GP*CP*C)-3', 5'-D(*GP*CP*AP*TP*TP*CP*AP*TP*GP*TP*C)-3', DNA-3-methyladenine glycosylase 2
著者Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
登録日2010-08-17
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.894 Å)
主引用文献Structure of Escherichia coli AlkA in Complex with Undamaged DNA.
J.Biol.Chem., 285, 2010
3OH9
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AlkA Undamaged DNA Complex: Interrogation of a T:A base pair
分子名称: 5'-D(*AP*CP*AP*(BRU)P*GP*AP*AP*(BRU)P*GP*CP*C)-3', 5'-D(*GP*GP*CP*AP*TP*TP*CP*AP*TP*GP*T)-3', DNA-3-methyladenine glycosylase 2
著者Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
登録日2010-08-17
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献Structure of Escherichia coli AlkA in Complex with Undamaged DNA.
J.Biol.Chem., 285, 2010
3OGD
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AlkA Undamaged DNA Complex: Interrogation of a G*:C base pair
分子名称: 5'-D(*CP*AP*(BRU)P*GP*AP*CP*(BRU)P*GP*C)-3', 5'-D(*GP*CP*AP*GP*TP*CP*AP*TP*G)-3', DNA-3-methyladenine glycosylase 2
著者Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
登録日2010-08-16
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Escherichia coli AlkA in Complex with Undamaged DNA.
J.Biol.Chem., 285, 2010
4G4O
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MutM containing M77A mutation bound to oxoG-containing DNA
分子名称: DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*(8OG)P*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3'), DNA (5'-D(P*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), Formamidopyrimidine-DNA glycosylase, ...
著者Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L.
登録日2012-07-16
公開日2013-02-20
最終更新日2013-04-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM.
J.Biol.Chem., 288, 2013
4G4R
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MutM containing F114A mutation bound to oxoG-containing DNA
分子名称: DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*(8OG)P*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3'), DNA (5'-D(P*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), Formamidopyrimidine-DNA glycosylase, ...
著者Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L.
登録日2012-07-16
公開日2013-02-20
最終更新日2013-04-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM.
J.Biol.Chem., 288, 2013
4G4N
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MutM containing M77A mutation bound to undamaged DNA
分子名称: DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*GP*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3'), DNA (5'-D(P*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), Formamidopyrimidine-DNA glycosylase, ...
著者Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L.
登録日2012-07-16
公開日2013-02-20
最終更新日2013-11-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM.
J.Biol.Chem., 288, 2013
4G4Q
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BU of 4g4q by Molmil
MutM containing F114A mutation bound to undamaged DNA
分子名称: DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*GP*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ...
著者Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L.
登録日2012-07-16
公開日2013-02-20
最終更新日2013-04-24
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM.
J.Biol.Chem., 288, 2013
2H6Q
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Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
分子名称: Histone H3 K4-Me3 9-residue peptide, WD-repeat protein 5
著者Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-06-01
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
2I5W
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Structure of hOGG1 crosslinked to DNA sampling a normal G adjacent to an oxoG
分子名称: 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*A)-3', 5'-D(P*CP*CP*AP*GP*(G42)P*TP*CP*TP*AP*C)-3', CALCIUM ION, ...
著者Banerjee, A, Verdine, G.L.
登録日2006-08-26
公開日2006-10-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A nucleobase lesion remodels the interaction of its normal neighbor in a DNA glycosylase complex.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2H6N
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Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
分子名称: Histone H3 K4-Me2 9-residue peptide, WD-repeat protein 5
著者Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-05-31
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
2H68
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Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
分子名称: WD-repeat protein 5
著者Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-05-30
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
2H6K
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Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
分子名称: Histone H3 K4-Me 9-residue peptide, WD-repeat protein 5
著者Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-05-31
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
8EI2
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Crystal structure of the N-terminal domain of CUL5 in complex with H314, a Helicon Polypeptide
分子名称: Cullin-5, H314, N,N'-(1,4-phenylene)diacetamide
著者Li, K, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H.
登録日2022-09-14
公開日2023-10-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides.
Nat Commun, 14, 2023
8EI3
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Crystal structure of VHL in complex with H313, a Helicon Polypeptide
分子名称: Elongin-B, Elongin-C, H313, ...
著者Li, K, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H.
登録日2022-09-14
公開日2023-10-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides.
Nat Commun, 14, 2023
8EI5
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Crystal structure of the WWP2 HECT domain in complex with H301, a Helicon Polypeptide
分子名称: 1,2-ETHANEDIOL, GLYCEROL, H301, ...
著者Li, K, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H.
登録日2022-09-14
公開日2023-10-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides.
Nat Commun, 14, 2023
8EI8
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Crystal structure of the WWP2 HECT domain in complex with H308, a Helicon Polypeptide
分子名称: 1,2-ETHANEDIOL, H308, N,N'-(1,4-phenylene)diacetamide, ...
著者Li, K, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H.
登録日2022-09-14
公開日2023-10-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides.
Nat Commun, 14, 2023
8EI9
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Crystal structure of beta-catenin and the MDM2 p53-binding domain in complex with H332, a Helicon Polypeptide
分子名称: Catenin beta-1, E3 ubiquitin-protein ligase Mdm2, H332, ...
著者Li, K, Travaline, T.L, Swiecicki, J.-M, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H.
登録日2022-09-14
公開日2023-10-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides.
Nat Commun, 14, 2023
8EIC
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Crystal structure of beta-catenin and the MDM2 p53-binding domain in complex with H330, a Helicon Polypeptide
分子名称: Catenin beta-1, E3 ubiquitin-protein ligase Mdm2, H330, ...
著者Li, K, Travaline, T.L, Swiecicki, J.-M, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H.
登録日2022-09-14
公開日2023-10-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides.
Nat Commun, 14, 2023
8EHZ
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Crystal structure of the STUB1 TPR domain in complex with H317, a Helicon Polypeptide
分子名称: E3 ubiquitin-protein ligase CHIP, H317, N,N'-(1,4-phenylene)diacetamide
著者Li, K, Swiecicki, J.-M, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H.
登録日2022-09-14
公開日2023-10-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides.
Nat Commun, 14, 2023

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