8EI3
Crystal structure of VHL in complex with H313, a Helicon Polypeptide
Summary for 8EI3
Entry DOI | 10.2210/pdb8ei3/pdb |
Descriptor | Elongin-B, Elongin-C, von Hippel-Lindau disease tumor suppressor, ... (5 entities in total) |
Functional Keywords | e3 ligase, complex, stapled peptide, ligase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 7 |
Total formula weight | 87823.67 |
Authors | Li, K.,Tokareva, O.S.,Thomson, T.M.,Verdine, G.L.,McGee, J.H. (deposition date: 2022-09-14, release date: 2023-10-25, Last modification date: 2023-11-15) |
Primary citation | Tokareva, O.S.,Li, K.,Travaline, T.L.,Thomson, T.M.,Swiecicki, J.M.,Moussa, M.,Ramirez, J.D.,Litchman, S.,Verdine, G.L.,McGee, J.H. Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides. Nat Commun, 14:6992-6992, 2023 Cited by PubMed: 37914719DOI: 10.1038/s41467-023-42395-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.49 Å) |
Structure validation
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